GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSEGF1 4704 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse mRNA encoding the precursor of the epidermal growth factor.
ACCESSION V00741
KEYWORDS epidermal growth factor; polyprotein.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 4704)
AUTHORS Gray,A., Dull,T.J. and Ullrich,A.
TITLE Nucleotide sequence of epidermal growth factor cDNA predicts a 128,
000-molecular weight protein precursor
JOURNAL Nature 303, 722-725 (1983)
STANDARD full automatic
COMMENT SWISS-PROT; P01132; EGF$MOUSE.
Data kindly reviewed (23-JUL-1985) by A. Ullrich
From EMBL entry MMEGF1; dated 06-JUL-1989.
FEATURES Location/Qualifiers
mRNA 1..4704
/note="messenger RNA"
CDS 310..3960
/note="polyprotein"
/codon_start=310
CDS 3288..3396
/note="epidermal growth factor"
/codon_start=3288
polyA_site 4704..4704
/note="polyA addition site"
BASE COUNT 1217 a 1098 c 1245 g 1144 t
ORIGIN
1 atctgcatat ttcgttgtta gcaccatccc tcatcccggt ggggcttgga actttccatc
61 aattctttcc tgtctcgttt ctctttcatc ctttgcctgg ttgtgcctgt ctcagggaga
121 aatcagtcac ctgcaggcct tgcagggctc ttaggctctg ggaaatttgt catacgggtg
181 tcaggtactt cttattgctg tccaaaggga aaaaaaaagt gagacaaaga actctcccgg
241 agcctttccg gctgcactca gaggctctcg agaggtgcag aaggacctgg aaaggcagct
301 aaataaaaga tgccctgggg ccgaaggcca acctggctgt tgctcgcctt cctgctggtg
361 tttttaaaga ttagcatact cagcgtcaca gcatggcaga ccgggaactg tcagccaggt
421 cctctcgaga gaagcgagag aagcgggact tgtgccggtc ctgccccctt cctagttttc
481 tcacaaggaa agagcatctc tcggattgac ccagatggaa caaatcacca gcaattggtg
541 gtggatgctg gcatctcagc agacatggat attcattata aaaaagagag actctattgg
601 gtggatgtag aaagacaagt tttgctaaga gttttcctta acgggacagg actagagaaa
661 gtgtgcaatg tagagaggaa ggtgtctggg ctggccatag actggataga tgatgaagtt
721 ctctgggtag accaacagaa cggagtcatc accgtaacag atatgacagg gaaaaattcc
781 cgagttcttc taagttcctt aaaacatccg tcaaatatag cagtggatcc aatagagagg
841 ttgatgtttt ggtcttcaga ggtgaccggc agccttcaca gagcacacct caaaggtgtt
901 gatgtaaaaa cactgctgga gacaggggga atatcggtgc tgactctgga tgtcctggac
961 aaacggctct tctgggttca ggacagtggc gaaggaagcc acgcttacat tcattcctgt
1021 gattatgagg gtggctccgt ccgtcttatc aggcatcaag cacggcacag tttgtcttca
1081 atggcctttt ttggtgatcg gatcttctac tcagtgttga aaagcaaggc gatttggata
1141 gccaacaaac acacggggaa ggacacggtc aggattaacc tccatccatc ctttgtgaca
1201 cctggaaaac tgatggtagt acaccctcgt gcacagccca ggacagagga cgctgctaag
1261 gatcctgacc ccgaacttct caaacagagg ggaagaccat gccgcttcgg tctctgtgag
1321 cgagacccca agtcccactc gagcgcatgc gctgagggct acacgttaag ccgagaccgg
1381 aagtactgcg aagatgtcaa tgaatgtgcc actcagaatc acggctgtac tcttgggtgt
1441 gaaaacaccc ctggatccta tcactgcaca tgccccacag gatttgttct gcttcctgat
1501 gggaaacaat gtcacgaact tgtttcctgc ccaggcaacg tatcaaagtg cagtcatggc
1561 tgtgtcctga catcagatgg tccccggtgc atctgtcctg caggttcagt gcttgggaga
1621 gatgggaaga cttgcactgg ttgttcatcg cctgacaatg gtggatgcag ccagatctgt
1681 cttcctctca ggccaggatc ctgggaatgt gattgctttc ctgggtatga cctacagtca
1741 gaccgaaaga gctgtgcagc ttcaggacca cagccacttt tactgtttgc aaattcccag
1801 gacatccgac acatgcattt tgatggaaca gactacaaag ttctgctcag ccggcagatg
1861 ggaatggttt ttgccttgga ttatgaccct gtggaaagca agatatattt tgcacagaca
1921 gccctgaagt ggatagagag ggctaatatg gatgggtccc agcgagaaag actgatcaca
1981 gaaggagtag atacgcttga aggtcttgcc ctggactgga ttggccggag aatctactgg
2041 acagacagtg ggaagtctgt tgttggaggg agcgatctga gcgggaagca tcatcgaata
2101 atcatccagg agagaatctc gaggccgcga ggaatagctg tgcatccaag ggccaggaga
2161 ctgttctgga cggacgtagg gatgtctcca cggattgaaa gcgcttccct tcaaggttcc
2221 gaccgggtgc tgatagccag ctccaatcta ctggaaccca gtggaatcac gattgactac
2281 ttaacagaca ctttgtactg gtgtgacacc aagaggtctg tgattgaaat ggccaatctg
2341 gatggctcca aacgccgaag acttatccag aacgacgtag gtcacccctt ctctctagcc
2401 gtgtttgagg atcacctgtg ggtctcggat tgggctatcc catcggtaat aagggtgaac
2461 aagaggactg gccaaaacag ggtacgtctt caaggcagca tgctgaagcc ctcgtcactg
2521 gttgtggtcc atccattggc aaaaccaggt gcagatccct gcttatacag gaatggaggc
2581 tgtgaacaca tctgccaaga gagcctgggt acagctcggt gtttgtgtcg tgaaggtttt
2641 gtgaaggcct gggatgggaa aatgtgtctc cctcagtatt atccaatcct gtcaggtgaa
2701 aatgctgatc ttagtaaaga ggtgacatca ctgagcaact ccactcaggc tgaagtacca
2761 gacgatgatg ggacagaatc ttccacacta gtggctgaaa tcatggtgtc aggcatgaac
2821 tatgaagatg actgtggtcc cggggggtgt ggaagccatg ctcgatgcgt ttcagacgga
2881 gagactgctg agtgtcagtg tctgaaaggg tttgccaggg atggaaacct gtgttctgat
2941 atagatgagt gtgtgctggc tagatcggac tgccccagca cctcgtccag gtgcatcaac
3001 actgaaggtg gctacgtctg cagatgctca gaaggctacg aaggagacgg gatctcctgt
3061 ttcgatattg acgagtgcca gcggggggcg cacaactgcg ctgagaatgc cgcctgcacc
3121 aacacggagg gaggctacaa ctgcacctgc gcaggccgcc catcctcgcc cggacggagt
3181 tgccctgact ctaccgcacc ctctctcctt ggggaagatg gccaccattt ggaccgaaat
3241 agttatccag gatgcccatc ctcatatgat ggatactgcc tcaatggtgg cgtgtgcatg
3301 catattgaat cactggacag ctacacatgc aactgtgtta ttggctattc tggggatcga
3361 tgtcagactc gagacctacg atggtgggag ctgcgtcatg ctggctacgg gcagaagcat
3421 gacatcatgg tggtggctgt ctgcatggtg tcactggtcc tgctgctcct cttggggatg
3481 tgggggactt actactacag gactcggaag cagctatcaa accccccaaa gaacccttgt
3541 gatgagccaa gcggaagtgt gagcagcagc gggcccgaca gcagcagcgg ggcagctgtg
3601 gcttcttgtc cccaaccttg gtttgtggtc ctagagaaac accaagaccc caagaatggg
3661 agtctgcctg cggatggtac gaatggtgca gtagtagatg ctggcctgtc tccctccctg
3721 cagctcgggt cagtgcatct gacttcatgg agacagaagc cccacataga tggaatggga
3781 acagggcaaa gctgctggat tccaccatca agtgacagag gaccccagga aatagaggga
3841 aactcccacc taccctccta cagacctgtg gggccggaga agctgcattc tctccagtca
3901 gctaatggat cgtgtcacga aagggctcca gacctgccac ggcagacaga gccagttcag
3961 tagaaactgg gagtagacag aaggtacaga agggaaaata acaaaccagg ctgatgatgg
4021 tagagtgcta cagacttggt actccagttt ccacggctaa tcactgctcg ctcagggtcc
4081 tgaagatagc tgcacagctg cagagctgca cagcgggata gctgcgactt ttgcttcttg
4141 ctttaagcag ttccactgaa gatactcaaa agagaagtgg agaaaatcat tagaaaccaa
4201 agtcaagaca ttcatatata agctgtgtct tcttcactgg acggtttgcc tcttttcctt
4261 ttgcctcaga aggagtgggt taaagcaggt gaccccatgc tctgtcaacc cctgaataaa
4321 tgatgtgatc tacatagaag tcttagctca ctctcaggaa cgcttggaac actataactt
4381 ttgctatgat atactgccaa gtgtggccca tgctcataat tgtgccttct gaattgtgat
4441 aaattagtga aaaaactgta actagaatct gatttattta ggattagatc atctttttat
4501 actataaaaa tcttcgaatg aaaatattta actttaaaaa cattacctta atcattgtct
4561 tttcttcttg aagtctttcc cagtgaaaac gctcaattct gctgtttcca tagaattttt
4621 aatttatttt aagacatgag attctaaaca aattgcttga tttattttat cctaattatt
4681 taaataaaat caccctaaag catc
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