GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSGSU1 1944 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germ line DNA sequence whose of unknown function rearranged
by an aberrant recombination event with J1 of the kappa
immunoglobulin genes.
ACCESSION V01562
KEYWORDS V-J joining; aberrant recombination; f-fragment; germline;
immunoglobulin; kappa-immunoglobulin; reciprocal recombination;
simple sequence DNA.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1721 to 1888)
AUTHORS Hoechtl,J., Mueller,C.R. and Zachau,H.G.
TITLE Recombined flanks of the variable and joining segments of
immunoglobulin genes
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 1383-1387 (1982)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1944)
AUTHORS Hoechtl,J. and Zachau,H.G.
TITLE A novel type of aberrant recombination in immunoglobulin genes and
its implications for V-J joining mechanism
JOURNAL Nature 302, 260-263 (1983)
STANDARD full automatic
COMMENT See the entry <MMARI1> for the recombined DNA sequence, this is the
germ line sequence. Data submitted (17-JAN-1984) on tape to the
EMBL data library by H.G. Zachau and P.S. Neumaier.
From EMBL entry MMGSU1; dated 06-DEC-1983.
FEATURES Location/Qualifiers
misc_feature 252..425
/note="simple sequence region"
misc_feature 884..948
/note="simple sequence region"
misc_feature 1721..1727
/note="conserved heptanucleotide box for the V-J
recombination"
BASE COUNT 438 a 464 c 405 g 637 t
ORIGIN
1 gaattcctgt agaggcccca agagggagtc agatcctgta gaaagttaca ggtaattgtg
61 atccaccaga tgtgggttct ggctcctctg caggagcagc agtgctttca ggctcagagc
121 caccctctgg ccctgggatt ggaattttta aatttcatat tttttatgtg gggtcctggg
181 gatttgaact cagtccctca tgcttgccca gcaagtgttt tactcactga gccctctccc
241 cagcctcttg atttccttcc ttccttcctt ccttccttcc ttccttcctt ccttccttcc
301 ttccttcctc cctccctccc tccctccctc cctccctccc tctctctctc tttctctctc
361 tctctctctc tctctctctc tctctctctc tctctctctt tctttctttc cttttttctt
421 tctttgctaa agaaattgac tttgaagata tttaaaaact gtacacagta agtcttaaat
481 tatcaggttt tactagagaa agatgatcta atggcatggt ttaagctaaa ctttgataag
541 tctttcaatt tgaatggcag atcctcagaa gaaggaaggt agtacaacct ggccttttgc
601 ataactagta agatgctaca gatggaatta tggctcatgt tctggtgtaa agacacagaa
661 gagtggagcc tctagtctga gctttggagt ttgttcagca gtgttcacat gtattgataa
721 cactaagaat acaggcctgg aaaatggctt agtgggtgaa ggcacttgct accaagtctg
781 acaacctgaa tccaagccct agaacttaca tggtagaaga agagaactaa ttcctcccca
841 aagccctttt accttcatat gtatgctatg gtacactcag ggatgtgtgt atgtctctct
901 cggtgcatgt gtgtgtgcgt gtgtgtgtgt ttgtgcatat gtgtgtgtac acatgaatgc
961 atgtgtatgc agacaagtga acaatataaa aaatagcaaa acaatttacc ttcctttgat
1021 ccttccctag gagctgttgt cagtacagtg ataatcacac ccagaagtgt ggtttgttag
1081 atattaaaaa gttacaagtg gggagatgaa gtctaggtaa tgttagcagt ttagtcaagg
1141 ccaaccaacc aggttgagaa ggagctaggg tcataatcag gttcgctagc tttacagctt
1201 gtcattttcc cactgcagtt ttgttagtat actgaagaca tgatgagata tttcctgcct
1261 ttattgacaa atcattccga ggcctgtttc ctttccctag gctgtggagc agacagcatg
1321 gaaccctagg cccttactta tggccaatgg cagtgctgtt ccctctttaa tttaatttcc
1381 cattcttttt gcttaagcag cagacagtgg gactacatac aagccaggat agcaacgatt
1441 ctttcctctg actctgccgt gttttctccc ttggtgttgg ggctcaagct agggtagaga
1501 aaaactggga atcttagggc aaatgtctcc acatctggat ggtctccatg ctgcgacact
1561 tggccccttc acggttgctc atctagcctg tgccctgcac cttcaggcca gctgggcagt
1621 gataaaaatc tgtttcattt cttcttttgc caagtccatc tgcactgcac aggtgcaggg
1681 ctggactctt aaaatagaaa ctttgttctg tgtgatgtgg cacagtggaa acccccctga
1741 cttcattacc tcatgttcag attaacgaaa tggtgatctg tcccttctct gtggcatttc
1801 cctggcttct atgagacctt tcgtttctca tttggcttct ctagtttctc cgtttgtaac
1861 aggacttgat cttggtggtg tcaagcttcc ttctgccttt gattccctgt gcctgtgctt
1921 ctgattagga ctgttttaga attc
//