GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIFNA1 1515 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse gene for interferon alpha 1 (MuIFN-alpha 1)
ACCESSION X01974 K01237 X01968
KEYWORDS alpha-interferon; interferon; signal peptide.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Shaw,G.D., Boll,W., Taira,H., Mantei,N., Lengyel,P. and
Weissmann,C.
TITLE Structure and expression of cloned murine ifn-alpha genes
JOURNAL Nucleic Acids Res. 11, 555-573 (1983)
STANDARD full staff_review
REFERENCE 2 (sites)
AUTHORS Zwarthoff,E.C., Mooren,A.T. and Trapman,J.
TITLE Organization, structure and expression of murine interferon alpha
genes
JOURNAL Nucleic Acids Res. 13, 791-804 (1985)
STANDARD full staff_review
REFERENCE 3 (bases 1 to 1515)
AUTHORS Kelley,K.A. and Pitha,P.M.
TITLE Characterization of a mouse interferon gene locus I. Isolation of a
cluster of four alpha interferon genes
JOURNAL Nucleic Acids Res. 13, 805-823 (1985)
STANDARD full automatic
COMMENT EPD; 17073; Mm IFN-a'1. SWISS-PROT; P01572; INA1$MOUSE.
Data kindly reviewed (06-NOV-1985) by P.M. Pitha-Rowe
From EMBL entry MMIFNA1; dated 06-JUL-1989.
FEATURES Location/Qualifiers
promoter 272..278
/note="TATA-box"
misc_feature 305..305
/note="mRNA 5' end"
CDS 372..938
/note="put. precursor MuIFN-alpha 1"
/codon_start=372
CDS 372..440
/note="put. signal peptide (aa -24 to -1)"
/codon_start=372
CDS 441..938
/note="put. mature MuIFN-alpha 1 (aa 1 to 166)"
/codon_start=441
BASE COUNT 452 a 302 c 320 g 441 t
ORIGIN
1 agactatttt acagaaaact ttgatttata ctaaatatgt aaatttcaag taaggacagt
61 ttatcagtac tgtaacagtt aatgaaagtt caaattagga aaagaaatgt aagaaagctt
121 ttgatgagga ccagtgaaag aggaagcaat aatgaaaacc acaatggttt agaaaacacc
181 cagacgcaag cagagaatga gttaaagaaa gtgaaaagac aagtggaaag tgatggaagg
241 gcattcagaa agtaaaaacc agtgtttgcc ctatttaaga cacattcacc caggatggtc
301 ttcagagaac ctagagggga aggatcagga ccaaacagtc cagaagacca gaagctttgg
361 caacactcac catggctagg ctctgtgctt tcctgatggt cctggcggtg atgagctact
421 ggccaacctg ctctctagga tgtgacctgc ctcagactca taacctcagg aacaagagag
481 ccttgacact cctggtacaa atgaggagac tctcccctct ctcctgcctg aaggacagga
541 aggactttgg attcccgcag gagaaggtgg atgcccagca gatcaagaag gctcaagcca
601 tccctgtcct gagtgagctg acccagcaga tcctgaacat cttcacatca aaggactcat
661 ctgctgcttg gaatgcaacc ctcctagact cattctgcaa tgacctccac cagcagctca
721 atgacctgca aggttgtctg atgcagcagg tgggggtgca ggaatttccc ctgacccagg
781 aagatgccct gctggctgtg aggaaatact tccacaggat cactgtgtac ctgagagaga
841 agaaacacag cccctgtgcc tgggaggtgg tcagagcaga agtctggaga gccctgtctt
901 cctctgccaa tgtgctggga agactgagag aagagaaatg agtcctgagc caaagtgtag
961 aggactcttc cagactagaa cactgtacct ctctgctcat atctctgtca tctcaaaact
1021 gtcattcatt ttggcaggaa ttcaaacaat ttgcctaaat atttctgtaa aggcacttgt
1081 tctctttcaa ttcagttcta tgtatacatg tatgtatgca tgtatgtatg tatgcttgta
1141 cgtatttatt tatttattta tttgtgttta tttattcact tatttaacta tctgtgtgat
1201 gtaacatata ttgcagcata atttggtaaa gttatgtttt ttataaatta ttactaaatg
1261 taacttgttt tatttgttca ttctttaatt attttaaaat tttatgttgt gtatactggt
1321 atttttcagt aaagaaatta tatacataat caagcttcca agtattgtag tacatatgac
1381 attgcatagt gttcaggcga ttagatttat ttctcatcca ttcatggtta attcctacgt
1441 cttttctttt ctcctgtgat cgtattcttc tgaatgccca gacaacacac tgttcaggga
1501 tcaggcataa gatct
//