GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIG15GV 420 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse mAB-15C5 mRNA for immunoglobulin gamma-1 chain, V-CH1 (part.)
ACCESSION X56392
KEYWORDS gamma-immunoglobulin; immunoglobulin.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 420)
AUTHORS Vandamme,A.M.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 420)
AUTHORS Vandamme,A.M., Bulens,F., Bernar,H., Nelles,L., Lijnen,H.R. and
Collen,D.
TITLE Construction and characterization of a recombinant murine
monoclonal antibody directed against human fibrin fragment-D dimer
JOURNAL Eur. J. Biochem. 192, 767-775 (1990)
STANDARD full automatic
COMMENT *source: strain=BALB/c; isolate=MA15C5; tissue=plasma; *source:
cell type=myeloma hybridoma (P3X63-Ag.8-6.5.3), rearranged;
*source: cell line=hybridoma 15C5; library=lambda ZapI; *source:
clone=lambda Zap-gamma(1)2. **map:chromosome=chromosome 12. This
sequence is of cDNA corresponding to themRNA for the antibody
MA1515 directed agains crosslinked human fibrin fragment D-dimer
Data kindly reviewed (27-NOV-1990) by Vandamme A.M.
From EMBL entry MMIG15GV; dated 21-DEC-1990.
FEATURES Location/Qualifiers
CDS <1..>420
/note="partial 15C5 Ig gamma-1 precursor"
/codon_start=1
CDS <1..33
/note="partial signal sequence (AA -11 to -1)"
/codon_start=1
misc_feature 34..384
/note="variable region (AA 1 - 117)"
CDS 34..>420
/note="mature 15C5 Ig gamma-1 (AA 1 - 129)"
/codon_start=34
misc_feature 385..>420
/note="partial constant region (AA 118 - 129)"
BASE COUNT 110 a 113 c 97 g 100 t
ORIGIN
1 tgcctggtga cattcccaag ctgtgtccta tcccaggtgc agctgaagca gtcaggacct
61 ggcctagtgc agccctcaca gagcctgtcc atcacctgca cagtctctgg tttctcatta
121 actacctatg gtgtacactg gattcgccag tctccaggaa agggtctgga gtggctggga
181 gtgatatgga gtggtggaag cacagactat aatgcagctt tcatatccag actgagcatc
241 aacaaggaca attccaagag ccaagttttc tttaaaatga acagtctgca agctaatgac
301 acagccatat attactgtgc cagaaattat tggggaacct ctatggacta ctggggtcaa
361 ggaacctcag tcaccgtctc ctcagccaaa acgacacccc catctgtcta tccactggcc
//