GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIG71 792 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germ line equivalent of the rearranged V kappa pseudogene T2
(see entry <MMIG21>).
ACCESSION V01564
KEYWORDS germline; immunoglobulin; kappa-immunoglobulin; signal peptide;
somatic mutations; variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 792)
AUTHORS Pech,M., Hoechtl,J., Schnell,H. and Zachau,H.G.
TITLE Differences between germ-line and rearranged immunoglobulin V kappa
coding sequences suggest a localized mutation mechanism
JOURNAL Nature 291, 668-670 (1981)
STANDARD full automatic
COMMENT Sequence is from strain BALB/c. Data submitted (17-JAN-1984) on
tape to the EMBL data library by H.G. Zachau and P.S. Neumaier.
From EMBL entry MMIG71; dated 06-DEC-1983.
FEATURES Location/Qualifiers
CDS 54..102
/note="first exon (signal peptide)"
/codon_start=54
intron 103..308
/note="first intron"
CDS 309..604
/note="second exon (signal and variable region gene L7)"
/codon_start=309
mutation 467..467
/note="point mutation, not silent"
mutation 481..481
/note="point mutation, silent"
mutation 537..537
/note="point mutation, not silent"
mutation 574..574
/note="point mutation, not silent"
mutation 593..593
/note="point mutation, not silent"
mutation 598..598
/note="point mutation, not silent"
misc_feature 607..613
/note="conserved heptanucleotide box for the V-J
recombination"
BASE COUNT 220 a 149 c 172 g 251 t
ORIGIN
1 gatctttctc agggatgtgt catggtccac acaaactcag ggaaagtttg aagatggtat
61 ccacacctca gttccttgta tttttgcttt tctggattcc aggtatgact gtttgggtgt
121 ggcaaaaaag tggagatgtt atttaaatac aaaattttct tgctttattt ggaagccaat
181 gtcacatggg aattgacttt cagtttaaag aaattgatac aataaaagtc atttattttt
241 ctaagttgtt tagaagtgac tttcatattc agtgttgtga tctactaatg tatcttctat
301 ttttccagcc tccagaggtg acatcttgct gactcagtct ccagccatcc tgtctgtgag
361 tccaggagaa agagtcagtt tctcctgcag ggccagtcag agcattggca caagcataca
421 ctggtatcag caaagaacaa atggttctcc aaggcttctc ataaagtatg cttctgagtc
481 tatctctggg atcccttcca ggtttagtgg cagtggatca gggacagatt ttactcttag
541 catcaacagt gtggagtctg aagatattgc agattattac tgtcaacaaa gtaatagctg
601 gccaaccaca gtgatgcaga ccatagcaaa aatcaccagg aaagcagaag gctgggttgc
661 tttagctatt tctggtggtg tctcaaactt cttcagagtg tttcacagat gcagccatgt
721 gtgatgttta caaaaatatg tggaatgaag aagccctaaa gttctgcttg actgtaacat
781 ctttgcattc ta
//