GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIG71 792 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germ line equivalent of the rearranged V kappa pseudogene T2 (see entry <MMIG21>). ACCESSION V01564 KEYWORDS germline; immunoglobulin; kappa-immunoglobulin; signal peptide; somatic mutations; variable region. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 792) AUTHORS Pech,M., Hoechtl,J., Schnell,H. and Zachau,H.G. TITLE Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism JOURNAL Nature 291, 668-670 (1981) STANDARD full automatic COMMENT Sequence is from strain BALB/c. Data submitted (17-JAN-1984) on tape to the EMBL data library by H.G. Zachau and P.S. Neumaier. From EMBL entry MMIG71; dated 06-DEC-1983. FEATURES Location/Qualifiers CDS 54..102 /note="first exon (signal peptide)" /codon_start=54 intron 103..308 /note="first intron" CDS 309..604 /note="second exon (signal and variable region gene L7)" /codon_start=309 mutation 467..467 /note="point mutation, not silent" mutation 481..481 /note="point mutation, silent" mutation 537..537 /note="point mutation, not silent" mutation 574..574 /note="point mutation, not silent" mutation 593..593 /note="point mutation, not silent" mutation 598..598 /note="point mutation, not silent" misc_feature 607..613 /note="conserved heptanucleotide box for the V-J recombination" BASE COUNT 220 a 149 c 172 g 251 t ORIGIN 1 gatctttctc agggatgtgt catggtccac acaaactcag ggaaagtttg aagatggtat 61 ccacacctca gttccttgta tttttgcttt tctggattcc aggtatgact gtttgggtgt 121 ggcaaaaaag tggagatgtt atttaaatac aaaattttct tgctttattt ggaagccaat 181 gtcacatggg aattgacttt cagtttaaag aaattgatac aataaaagtc atttattttt 241 ctaagttgtt tagaagtgac tttcatattc agtgttgtga tctactaatg tatcttctat 301 ttttccagcc tccagaggtg acatcttgct gactcagtct ccagccatcc tgtctgtgag 361 tccaggagaa agagtcagtt tctcctgcag ggccagtcag agcattggca caagcataca 421 ctggtatcag caaagaacaa atggttctcc aaggcttctc ataaagtatg cttctgagtc 481 tatctctggg atcccttcca ggtttagtgg cagtggatca gggacagatt ttactcttag 541 catcaacagt gtggagtctg aagatattgc agattattac tgtcaacaaa gtaatagctg 601 gccaaccaca gtgatgcaga ccatagcaaa aatcaccagg aaagcagaag gctgggttgc 661 tttagctatt tctggtggtg tctcaaactt cttcagagtg tttcacagat gcagccatgt 721 gtgatgttta caaaaatatg tggaatgaag aagccctaaa gttctgcttg actgtaacat 781 ctttgcattc ta //