GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIG72 1176 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germ line immunoglobulin V kappa light chain gene segment.
ACCESSION V01565
KEYWORDS f-fragment; germline; immunoglobulin; kappa-immunoglobulin;
signal peptide; variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 893 to 1006)
AUTHORS Steinmetz,M., Altenburger,W. and Zachau,H.G.
TITLE A rearranged DNA sequence possibly related to the translocation of
immunoglobulin gene segments
JOURNAL Nucleic Acids Res. 8, 1709-1720 (1980)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1176)
AUTHORS Hoechtl,J., Mueller,C.R. and Zachau,H.G.
TITLE Recombined flanks of the variable and joining segments of
immunoglobulin genes
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 1383-1387 (1982)
STANDARD full automatic
COMMENT Sequence is taken from strain BALB/c. The 3'-flank of this V gene
segment is involved in recombination leading to the f-fragment T3
(see entry <MMIGF1> for the sequence). Data submitted
(17-JAN-1984) on tape to the EMBL data library by H.G. Zachau and
P.S. Neumaier.
From EMBL entry MMIG72; dated 06-DEC-1983.
FEATURES Location/Qualifiers
CDS 359..407
/note="first exon (signal peptide)"
/codon_start=359
intron 408..583
/note="first intron"
CDS 584..891
/note="second exon (signal peptide and variable region
gene L8)"
/codon_start=584
misc_feature 893..899
/note="conserved heptanucleotide box for the V-J
recombination"
BASE COUNT 339 a 243 c 218 g 376 t
ORIGIN
1 atataggtca aactagtcaa ttgaacatcc cttgtttagt ggatcaaata aatcttgtat
61 ttagggaaaa tatatggata atactatagg ataaggcttt tcctcataaa aatgaaaaat
121 gaggaaacag aaatttgctt ctttttcagt gtagtgaatg caaataaata gatattgtca
181 tggcttaacc tgatttgcct tagttaacag accaagttat aagccaagaa ctgcttatac
241 tatatcttgc tatttgcata cttcatcttc tgtaaccaca aatatctcac agttctttta
301 aagcaaagta cttgtgagaa tagcaggaat tagccaggga ctaaaattca aagacacaat
361 ggatttacag gtgcagatta tcagcttcct gctaatcatt gtcacaggta acagagggca
421 gggagtttga gatcagaatg caactaaaat tcttttttcc tggggaattt gagtctaaaa
481 tgtacttttt ttctttttct tacatctaaa tgttgaatgg tataaaatta ttttttacct
541 ctatttctac taatccatct tcctctatgt ctcttctttt cagtcataat gtccagagga
601 gaaaatgtgc tcacccagtc tccagcaata atggctgcct ctctggggga gaaggtcacc
661 atgacctgca gtgccagctc aagtgtaagt tccagctact tgcactggta ccagcagaag
721 tcaggcactt cccccaaact ctggatttat ggcacatcca acctggcttc tggagtccca
781 gctcgcttca gtggcagtgg ggctgggatc tcttactctc tcacaatcag cagcatggag
841 gctgaaaatg atgcaactta ttactgccag cagtggagtg gttacccatt cacacagtgc
901 tacagactgg aacaaaaaca ctgtaactcc ttagggccct gctacttcct cctagaaata
961 aactgtggcc agtggtttga ttgcagtagt ccacacaggg tgttctgctt cacaaagtca
1021 tttgcatctt tggatgactg tctctttaat aatccactgc tcttctcaaa taattcagtg
1081 ctgttctcaa ataatctttt tattgccagt gtttatttat tctcaatatt tttcctgatt
1141 tttgaagaca agtgtgacag gcacttctca tcagct
//