GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGF3 222 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse reciprocal recombination product of a rearrangement between
L10 (see entry <MMGSU1>) and the kappa immunoglobulin J1 gene
segment; contains the 5'-flank of J1 and the 3'-flank of L10;
f-fragment f-41.
ACCESSION V01568
KEYWORDS aberrant recombination; f-fragment; immunoglobulin; joining region;
kappa-immunoglobulin; rearranged DNA; reciprocal recombination;
variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 54)
AUTHORS Sakano,H., Hueppi,K., Heinrich,G. and Tonegawa,S.
TITLE Sequences at the somatic recombination sites of immunoglobulin
light-chain genes
JOURNAL Nature 280, 288-294 (1979)
STANDARD full automatic
REFERENCE 2 (bases 1 to 54)
AUTHORS Max,E.E., Seidman,J.G. and Leder,P.
TITLE Sequences of five potential recombination sites encoded close to an
immunoglobulin kappa constant region gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 76, 3450-3454 (1979)
STANDARD full automatic
REFERENCE 3 (bases 1 to 54)
AUTHORS Max,E.E., Maizel,J.V.Jr.. and Leder,P.
TITLE The nucleotide sequence of a 5.5-kilobase DNA segment containing
the mouse kappa immunoglobulin J and C region genes
JOURNAL J. Biol. Chem. 256, 5116-5120 (1981)
STANDARD full automatic
REFERENCE 4 (bases 1 to 222)
AUTHORS Hoechtl,J., Mueller,C.R. and Zachau,H.G.
TITLE Recombined flanks of the variable and joining segments of
immunoglobulin genes
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 1383-1387 (1982)
STANDARD full automatic
REFERENCE 5 (bases 6 to 93)
AUTHORS Hoechtl,J. and Zachau,H.G.
TITLE A novel type of aberrant recombination in immunoglobulin genes and
its implications for V-J joining mechanism
JOURNAL Nature 302, 260-263 (1983)
STANDARD full automatic
COMMENT Sequence is taken from strain BABL/c. This f-fragment is the
reciprocal recombination product of the aberrant recombination
leading to the formation of the K-41 fragment (see entry <MMARI1>
for the sequence of K-41). Data submitted (17-JAN-1984) on tape to
the EMBL data library by H.G. Zachau and P.S. Neumaier.
From EMBL entry MMIGF3; dated 06-JUL-1989.
FEATURES Location/Qualifiers
misc_feature 1..54
/note="5'-flank of J1"
misc_feature 48..54
/note="heptanucleotide box"
misc_feature 55..222
/note="3'-flank of L10 (see entry <MMGSU1>)"
misc_feature 55..61
/note="heptanucleotide box"
BASE COUNT 42 a 54 c 49 g 77 t
ORIGIN
1 ctcttcagtg aggagggttt ttgtacagcc agacagtgga gtactaccac tgtgcacagt
61 ggaaaccccc ctgacttcat tacctcatgt tcagattaac gaaatggtga tctgtccctt
121 ctctgtggca tttccctggc ttctatgaga cctttcgttt ctcatttggc ttctctagtt
181 tctccgtttg taacaggact tgatcttggt ggtgtcaagc tt
//