GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGKL 938 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse mRNA for Ig C.C58 M75 kappa light chain (VK Ser-group)
ACCESSION X02816
KEYWORDS constant region; immunoglobulin; immunoglobulin light chain;
joining region; signal peptide; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 938)
AUTHORS Goldrick,M.M., Boyd,R.T., Ponath,P.D., Lou,S.Y. and Gottlieb,P.D.
TITLE Molecular genetic analysis of the VkSer group associated with two
mouse light chain genetic markers
JOURNAL J. Exp. Med. 162, 713-728 (1985)
STANDARD full automatic
COMMENT BALB/C mice germline V(K1) region see MMIG25, C(K) region see
MMIGKC
Data kindly reviewed (24-FEB-1986) by P.D. Gottlieb
From EMBL entry MMIGKL; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 36..737
/note="(K)L-chain precursor"
/codon_start=36
CDS 36..95
/note="signal peptide (aa -20 to -1)"
/codon_start=36
CDS 96..737
/note="mature (K)L-chain (aa 1-214)"
/codon_start=96
CDS 96..380
/note="V region"
/codon_start=96
misc_feature 165..197
/note="put. CDR1"
misc_feature 243..263
/note="put. CDR2"
misc_feature 360..380
/note="put. CDR3"
misc_feature 381..382
/note="CC is TG in germline J(K1) of BALB/ C"
CDS 381..416
/note="J region"
/codon_start=381
misc_feature 416..416
/note="T is A in germline J(K1) of BALB/C"
CDS 417..737
/note="C region"
/codon_start=417
misc_feature 710..710
/note="C is T in germline C(K) of BALB/C"
BASE COUNT 248 a 260 c 206 g 224 t
ORIGIN
1 gcgcggggat acatcaggca ggcaaaggca tcaagatgaa gtcacagacc caggtcttca
61 tatttctact gctctgtgtg tctggtgctc atgggagtat tgtgatgacc cagactccca
121 aattcctgcc tgtatcagca ggagacaggg ttaccatgac ctgcaaggcc agtcagagtg
181 tgggtaataa tgtagcctgg taccaacaga agccaggaca gtctcctaaa ttgctgatat
241 actatgcatc caatcgctac actggagtcc ctgatcgctt cactggcagt ggatctggga
301 cagatttcac tttcaccatc agcagtgtgc aggttgaaga cctggcagtt tatttctgtc
361 agcaacatta tacctctcct ccgacgttcg gtggaggcac caagctggaa atcaatcggg
421 ctgatgctgc accaactgta tccatcttcc caccatccag tgagcagtta acatctggag
481 gtgcctcagt cgtgtgcttc ttgaacaact tctaccccaa agacatcaat gtcaagtgga
541 agattgatgg cagtgaacga caaaatggcg tcctgaacag ttggactgat caggacagca
601 aagacagcac ctacagcatg agcagcaccc tcacgttgac caaggacgag tatgaacgac
661 ataacagcta tacctgtgag gccactcaca agacatcaac ttcacccatc gtcaagagct
721 tcaacaggaa tgagtgttag agacaaaggt cctgagatgc caccaccagc tccccagctc
781 catcctatct tcccttctaa ggtcttggag gcttccccac aagcgaccta ccactgttgc
841 ggtgctccaa acctcctccc cacctccttc tcctcctcct ccctttcctt ggcttttatc
901 atgctaatat ttgcagaaaa tattcaataa agtgagtc
//