GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGKVD 1307 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse kappa germline V-region gene; subgroup VK-1 idiotype;
anti-GAT.
ACCESSION D00080
KEYWORDS germline; immunoglobulin; immunoglobulin light chain;
kappa-immunoglobulin; variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1307)
AUTHORS Corbet,S., Milili,M., Fougereau,M. and Schiff,C.
TITLE Two V-kappa germ-line genes related to the Gat idiotypic network
(Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse
V-kappa-1 variability subgroup
JOURNAL J. Immunol. 138, 932-939 (1987)
STANDARD full automatic
COMMENT V kappa Ig germ-line genes have been isolated from recombinant
clones prepared in separate libraries constructed from adult BALB/c
liver DNA. Three different clones, K5.1, K1A5, K18.1, that strongly
hybridized with a V kappa-GAT-specific probe were completely
characterized and sequenced.
From EMBL entry MMIGKVA; dated 25-APR-1990.
FEATURES Location/Qualifiers
CDS 342..387
/note="Ig kappa chain, exon 1"
/codon_start=342
CDS 342..387
/note="Ig kappa chain signal peptide"
/codon_start=342
CDS 769..1079
/note="Ig kappa chain, exon 2"
/codon_start=769
CDS 769..779
/note="Ig kappa chain signal peptide"
/codon_start=769
CDS 780..1079
/note="Ig kappa chain mature peptide"
/codon_start=780
BASE COUNT 367 a 266 c 300 g 374 t
ORIGIN
1 aagcttacca ggttattaac aaaatccact cgcaatcgtc tgggtgaaaa ataaatatac
61 atttctttta ttgaggagac agccctgtgt gagtcatatt cctggtatct cgggtgctta
121 tctgtgaaca ctctacagca tagaagaggt tttgtgtcca cttttaaaat cttaactagt
181 ctatataact cttccttcta tactgcaaca ctaaagggag cttttgcata ttgctcccca
241 gggagggccc acccttacta gtctgagata aaagctcagc tgtcttgttt cagtgactga
301 tcagtctcct caggctgtct cctcgaggtt gcctcctcaa aatgaagttg cctgttaggc
361 tgttggtgct gatgttctgg attcctggtg aggagagagg gaagtgaggg aggagaatgg
421 acagggagca ggagcactga atcccattgc tcattccatg tattctgcca tgggtgagaa
481 gatgggtctt atctccagca tggggcctct ggggtgaata cttgttagag ggaggttcca
541 gatgggaaca tgtgctataa tgaagattat gaaatggatg cctgggatgg tctaagtaat
601 gcctagaagt gactagacac ttgcaattca ctttttttgg taagaagaga attttaggat
661 ataaaaaaat ggtatgtaaa aataaacatc acagttgaaa taaaaaaaaa acataaggat
721 gttcatgaat tttgtgtgta actatgtatt tctctctcat tgtttcagct tccagcagtg
781 atgttgtgat gacccaaact ccactctccc tgcctgtcag tcttggagat caagcctcca
841 tctcttgcag atctagtcag agccttgtac acagtaatgg aaacacctat ttacattggt
901 acctgcagaa gccaggccag tctccaaagc tcctgatcta caaagtttcc aaccgatttt
961 ctggggtccc agacaggttc agtggcagtg gatcagggac agatttcaca ctcaagatca
1021 gcagagtgga ggctgaggat ctgggagttt atttctgctc tcaaagtaca catgttcctc
1081 ccacagtgat acagacccta acaaaaatag tcttactttg ggtatcccag ctgctaaata
1141 tgttatttat gtgtgagaga ggttctgagg gactccagat tattggttcc agctgagggc
1201 aagtgcagcc gtgctacaga tcactggtca ttcatttttg gcttcattgc cacaataaca
1261 atgtgaacag gtgccctccc agaagccaga aaaaaaatac ttaaaaa
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGKVB2 1306 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse kappa germline V-region gene; subgroup VK-1 idiotype;
anti-GAT.
ACCESSION D00081
KEYWORDS germline; immunoglobulin; immunoglobulin light chain;
kappa-immunoglobulin; variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1306)
AUTHORS Corbet,S., Milili,M., Fougereau,M. and Schiff,C.
TITLE Two V-kappa germ-line genes related to the Gat idiotypic network
(Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse
V-kappa-1 variability subgroup
JOURNAL J. Immunol. 138, 932-939 (1987)
STANDARD full automatic
COMMENT V kappa Ig germ-line genes have been isolated from recombinant
clones prepared in separate libraries constructed from adult BALB/c
liver DNA. Three different clones, K5.1, K1A5, K18.1, that strongly
hybridized with a V kappa-GAT-specific probe were completely
characterized and sequenced.
From EMBL entry MMIGKVB2; dated 25-APR-1990.
FEATURES Location/Qualifiers
CDS 347..392
/note="Ig kappa chain, exon 1"
/codon_start=347
CDS 770..1080
/note="Ig kappa chain, exon 2"
/codon_start=770
BASE COUNT 365 a 262 c 293 g 386 t
ORIGIN
1 aagcttacca ggttattaac aaaatcactc tcaatcgtct gggtgaaaaa taaatataca
61 tttcttttat tgaggagaca gctctgtgtg agtcacattc ctggtatttc gggtgcttat
121 ctgtgaacac tcatgctgtc tacagcatag aagaggtttt gtgtcatttt tacaatcata
181 acaagtctgt ataactcttc cttctatact gcaacactaa agggagcttt tgcatattgc
241 tccccaggga gggcccaccc ttactagtct gagataaaag ctcagctgtc ttgtttcagt
301 gactgatcag tctcctcagg ctgtctcctc aggttgcctc ctcaaaatga agttgcctgt
361 taggctgttg gtgctgatgt tctggattcc tggtgaggag agagggaagt gagggaggag
421 aatgaacagg gagcaggagc actgaatccc attgctcatt ccatatattc tgccatgggt
481 gagaagatgg gtcttatctc cagcatgggg cctcgggagt gaatacttgt tagagggagg
541 ttccagatgg gaacatgtac tataatgaag attatgacat ggatgcattg gatggtctgt
601 tatgcctaga agtgacttga cacttgcatt ttactttttt ggtaacaaga gaattttagg
661 atataaaaaa atggtatgta aaaataaaca tcacagttga aataaaaaaa atcataagga
721 tgttcatgaa ttttgtgtgt aactctgtat ttctctctca ttgtttcagc ttccagcagt
781 gatgttttga tgacccaaac tccactctcc ctgcctgtca gtcttggaga tcaagcctcc
841 atctcttgca gatctagtca gagcattgta catagtaatg gaaacaccta tttagaatgg
901 tacctgcaga aaccaggcca gtctccaaag ctcctgatct acaaagtttc caaccgattt
961 tctggggtcc cagacaggtt cagtggcagt ggatcaggga cagatttcac actcaagatc
1021 agcagagtgg aggctgagga tctgggagtt tattactgct ttcaaggttc acatgttcct
1081 cccacagtga tacagaccct aacaaaaata gtcttacttt gggtatcaca gctgctaaat
1141 atgttattca tgtttgagag aggttctgag ggactccagt ttattggttc cagctgaggg
1201 caagtgcagc ctggctacag ctcactggtc attcattttt ggcttcattg ccacaataac
1261 aatatgaaca gtgccctccc agaagccaga aaaaaatatt taaaaa
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGKVH 878 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse Kappa germline V-region gene; subgroup VK-1 idiotype;
anti-GAT.
ACCESSION D00082
KEYWORDS germline; immunoglobulin; immunoglobulin light chain;
kappa-immunoglobulin; variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 878)
AUTHORS Corbet,S., Milili,M., Fougereau,M. and Schiff,C.
TITLE Two V-kappa germ-line genes related to the Gat idiotypic network
(Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse
V-kappa-1 variability subgroup
JOURNAL J. Immunol. 138, 932-939 (1987)
STANDARD full automatic
COMMENT V kappa Ig germ-line genes have been isolated from recombinant
clones prepared in separate libraries constructed from adult BALB/c
liver DNA. Three different clones, K5.1, K1A5, K18.1, that strongly
hybridized with a V kappa-GAT-specific probe were completely
characterized and sequenced.
From EMBL entry MMIGKVC; dated 25-APR-1990.
FEATURES Location/Qualifiers
CDS 83..128
/note="Ig kappa chain, exon 1"
/codon_start=83
CDS 517..827
/note="Ig kappa chain, exon 2"
/codon_start=517
BASE COUNT 239 a 176 c 222 g 241 t
ORIGIN
1 ggcccatcct tactaggatg agataaaagt tcagttgtca tgttgcagtg actgatcagt
61 ctcctcaggc tccctcctca aaatgaagtt gcctgttagg ctgttggtgc tgatgttctg
121 gattcctggt gaggagagag ggaagtgagg gaggagaatg gacagggagc aggagcactg
181 aatcccattg ctcattccat atattctgcc atgggtgaga agatgggtct tatctccagc
241 atggggcctc ggggatgaat atttgttaga gggaggttcc agatgggaac atgtgctata
301 atgaagatta tgacatggat gcatgggatg gtttaagata tgcctagaag tgccttggga
361 cttgcttggg actcactttt ttggtaagaa gagaatttta gggtattaaa aatggtatgt
421 aaaaataaac aacatagttg aaattaaaaa acaaaaggcc acaaggatgt tcagaaattt
481 tgtgtataac tttgtacttc tctctcattg tttcagcttc cagcagtgat gctgtgatga
541 cccaaactcc actctccctg cctgtcagtc ttggagatca agcctccatc tcttgcaggt
601 ctagtcagag ccttgaaaac agtaatggaa acacctattt gaactggtac ctccagaaac
661 caggccagtc tccacagctc ctgatctaca gggtttccaa ccgattttct ggggtcctag
721 acaggttcag tggtagtgga tcagggacag atttcacact gaaaatcagc agagtggagg
781 ctgaggattt gggagtttat ttctgcctcc aagttacaca tgtccctccc acagtgatgc
841 agaccctaac aaaaacattt tgctagggat gcccagct
//