GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGMSMJ 366 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse mRNA for variable region of IgM heavy immunoglobulin chain
ACCESSION X53097
KEYWORDS autoantibody; immunoglobulin heavy chain; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 366; 21 to 366)
AUTHORS Carmarck,C.E.
JOURNAL Unpublished (1990)
STANDARD full automatic
COMMENT *source: strain=SM/J; tissue=spleen; cell type=B-lymphocyte;
*source: cell line=1-6C10 hybridoma (with SP2/0); **map:
chromosome=12;
From EMBL entry MMIGMSMJ; dated 15-AUG-1990.
FEATURES Location/Qualifiers
CDS 1..366
/note="IgM heavy chain variable region (122 AA)"
/codon_start=1
CDS 1..21
/note="leader (7 AA)"
/codon_start=1
CDS 22..108
/note="framework 1 (29 AA)"
/codon_start=22
CDS 109..132
/note="CDR1 (8 AA)"
/codon_start=109
CDS 133..174
/note="framework 2 (14 AA)"
/codon_start=133
CDS 175..222
/note="CDR2 (16 AA)"
/codon_start=175
CDS 223..318
/note="framework 3 (32 AA)"
/codon_start=223
CDS 319..336
/note="CDR3 or D segment (6 AA)"
/codon_start=319
CDS 337..366
/note="joining (2) region (10 AA)"
/codon_start=337
BASE COUNT 85 a 98 c 93 g 90 t
ORIGIN
1 gatgtccagc atatctcctt ccaggttact ctgaaagagt ctggccctgg gatattgcag
61 ccctcccaga ccctcagtct gacttgttct ttctctgggt tttcactgag cacttctggt
121 atgggtgtga gctggattcg tcagccttca ggaaagggtc tggagtggct ggcacacatt
181 tactgggatg atgacaagcg ctataaccca tccctgaaga gccggctcac aatctccaag
241 gatacctcca gaaaccaggt attcctcaag atcaccagtg tggacactgc agatactgcc
301 acatactact gtgctcgaag agagggggga cgtagctact ttgactactg gggccaaggc
361 accact
//