[bionet.molbio.genbank.updates] Mouse mRNA for idiotypic anti-NP IgG

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGGNP1     414 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-J (hybridoma
            20.1.43)
ACCESSION   X02562
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGGNP1;  dated 10-JAN-1991.
FEATURES             Location/Qualifiers
     CDS             join(58..351,352..366,367..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-J"
                     /codon_start=58
     sig_peptide     1..57
     misc_feature    58..351
     misc_feature    58..351
                     /note="variable region (aa 1-98)"
     misc_feature    148..162
                     /note="CDR 1"
     misc_feature    205..255
                     /note="CDR 2"
     misc_feature    352..366
     misc_feature    352..366
                     /note="D-region (aa 99-103)"
     misc_feature    367..>414
                     /note="J-region (aa 104-119)"
BASE COUNT      101 a     98 c    118 g     97 t
ORIGIN
        1 atgaaatgca gctgggttat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgg ggcagagctt gtgaggccag gggcctcagt caagttgtcc
      121 tgcacagctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggcct
      181 gaacagggcc tggagtggat tggaaggatt gatcctgcga atggtaatac taaatatgac
      241 ccgaagttcc agggcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag ttataggtac
      361 gagagggcct ggtttgctta ctggggccaa gggactctgg tcactgtctc tgca
//

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGGNP2     420 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J
            (hybridoma 18.1.16)
ACCESSION   X02563
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGGNP2;  dated 10-JAN-1991.
FEATURES             Location/Qualifiers
     mat_peptide     join(58..351,352..375,376..420)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
     CDS             join(1..351,352..375,376..420)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
                     /codon_start=1
     sig_peptide     1..57
     misc_feature    58..351
     misc_feature    58..351
                     /note="variable region (aa 1-98)"
     misc_feature    148..162
                     /note="CDR I"
     misc_feature    205..255
                     /note="CDR II"
     misc_feature    352..375
     misc_feature    352..375
     misc_feature    352..375
                     /note="D-region (aa 99-106)"
     misc_feature    376..>420
                     /note="J-region (aa 107-121)"
BASE COUNT      107 a    106 c    110 g     97 t
ORIGIN
        1 atgaaatgca gctgggttat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgg ggcagagctt gtgaagccag gggcctcagt caagttgtcc
      121 tgcacggctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggcct
      181 gaacagggcc tggagtggat tggaaggatt gatcctgcga atggtaatac taaatatgac
      241 ccgaagttcc agggcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag atacctctat
      361 tactacggta gtagcgactt tgactactgg ggccaaggca ccactctcac agtctcctca
//

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGGNP3     414 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J
            (hybridoma P.5.40.1/group VI)
ACCESSION   X02564
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGGNP3;  dated 10-JAN-1991.
FEATURES             Location/Qualifiers
     mat_peptide     join(58..351,352..371,372..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
     CDS             join(1..351,352..371,372..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
                     /codon_start=1
     sig_peptide     1..57
     misc_feature    58..351
     misc_feature    58..351
                     /note="variable region"
     misc_feature    148..162
                     /note="CDR I"
     misc_feature    205..255
                     /note="CDR II"
     misc_feature    352..371
     misc_feature    352..371
     misc_feature    352..371
                     /note="D-region (aa 99-105)"
     misc_feature    372..>414
                     /note="J-region (aa 106-119)"
BASE COUNT      102 a    101 c    111 g    100 t
ORIGIN
        1 atgaaattca gctgggtcat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgt ggcagagctt gtgaggccag gggcctcagt caagttgtcc
      121 tgcacagctt ctggcttcaa cattaaaaac acctatatgc actgggtgaa gcagaggcct
      181 gaacagggcc tggagtggat tggaaggatt gatcctgcga atggtagtac taagtatgcc
      241 ccgaagttcc agatcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccatctatt actgtgctag gtattactac
      361 gagagtagcc tgtttgctta ctggggccaa gggactctgg tcactgtctc tgca
//

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGGNP6     417 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J
            (hybridoma P.4.6.1; group V)
ACCESSION   X02567
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGGNP6;  dated 10-JAN-1991.
FEATURES             Location/Qualifiers
     mat_peptide     join(58..147,352..>417)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
     CDS             join(1..147,352..>417)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
                     /codon_start=1
     sig_peptide     1..57
     misc_feature    58..147
     misc_feature    58..147
                     /note="V-region (aa 1-98)"
     misc_feature    148..162
                     /note="CDR I"
     misc_feature    205..255
                     /note="CDR II"
     misc_feature    352..360
                     /note="D-region (aa 99-104)"
     misc_feature    361..>417
                     /note="J-region (aa 105-120)"
BASE COUNT      105 a    100 c    112 g    100 t
ORIGIN
        1 atgaaatgca gctggatcat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgg ggcagagctt gtgaagccag gggcctcagt caagttgtcc
      121 tgcacagctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggact
      181 gaacagggcc tggagtggat tggaaggatt gatcctgagg atggtgaaac taaatatgcc
      241 ccgaaattcc tgatcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag atacgattat
      361 tactacgggt cctggtttgc ttactggggc caagggactc tggtcactgt ctctgca
//

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGGNP7     414 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J
            (hybridoma P.4.16.25; group V)
ACCESSION   X02568
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C m ice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGGNP7;  dated 10-JAN-1991.
FEATURES             Location/Qualifiers
     mat_peptide     join(58..147,352..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
     CDS             join(1..147,352..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
                     /codon_start=1
     sig_peptide     1..57
     misc_feature    58..147
     misc_feature    58..147
                     /note="V-region (aa 1-98)"
     misc_feature    148..162
                     /note="CDR I"
     misc_feature    205..255
                     /note="CDR II"
     misc_feature    352..365
                     /note="D-region (aa 99-103)"
     misc_feature    366..>414
                     /note="J-region (aa 104-119)"
BASE COUNT      107 a    103 c    108 g     96 t
ORIGIN
        1 atgaaatgca gctggatcat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgg ggcagagctt gtgaggccag gggcctcagt caagttgtcc
      121 tgcacagctt ctggcttcaa cattaaagac tactatatgc actgggtgaa gcagaggact
      181 gaacagggcc tggagtggat tggaaggatt gatcctgagg atggtgaaac taaatatgcc
      241 ccgaaattcc aggtcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag atattactac
      361 ggtgctgact actttgacta ctggggccaa ggcaccactc tcacagtctc ctca
//

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGGNP8     414 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J
            (hybridoma P.3.6.5)
ACCESSION   X02569
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGGNP8;  dated 10-JAN-1991.
FEATURES             Location/Qualifiers
     mat_peptide     join(58..147,352..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
     CDS             join(1..147,352..414)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D-J"
                     /codon_start=1
     sig_peptide     1..57
     misc_feature    58..147
     misc_feature    58..147
                     /note="V-region (aa 1-98)"
     misc_feature    148..162
                     /note="CDR I"
     misc_feature    205..255
                     /note="CDR II"
     misc_feature    352..372
                     /note="D-region (aa 99-105)"
     misc_feature    373..>414
                     /note="J-region (aa 106-119)"
BASE COUNT      102 a    100 c    114 g     98 t
ORIGIN
        1 atgaaatgca gctggatcat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgg ggcagagctt gtgaggccag gggcctcagt caagtggtcc
      121 tgcacggctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggact
      181 gaacagggcc tggagtggat tggaaggatt gatcctgagg atggtgaaac taaatatgcc
      241 ccgaaattcc aggtcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag ctattactac
      361 ggtagtagct tctttgctta ctggggccaa gggactctgg tcactgtctc tgca
//

GenBank-Updates@genbank.bio.net (05/27/91)

LOCUS       MUSIGNP4      411 bp ss-mRNA            ROD       27-MAY-1991
DEFINITION  Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J
            (hybridoma P.10.15.1/group VI)
ACCESSION   X02565
KEYWORDS    diversity region; gamma-immunoglobulin; immunoglobulin;
            immunoglobulin heavy chain; joining region; signal peptide;
            variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and
            Imanishi-Kari,T.
  TITLE     Heavy chain variable region Multiple gene segments encode
            anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies
  JOURNAL   J. Exp. Med. 161, 1272-1292 (1985)
  STANDARD  full automatic
COMMENT     Serological analysis of hybridomaproteins resulting from the immune
            response to the hapten NP reveals NP(a) idiotypes expressed by
            Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The
            NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV
            sharing more determinants than V and VI which appear quite
            distinct.
            
            From EMBL    entry MMIGNP4;  dated 16-JAN-1991.
FEATURES             Location/Qualifiers
     CDS             join(58..411)
                     /product="idiotypic anti-NP IgG(1) heavy chain V-D- J"
                     /codon_start=58
     sig_peptide     1..57
     misc_feature    58..351
                     /note="variable region (aa 1-98)"
     misc_feature    148..162
                     /note="CDR I"
     misc_feature    205..255
                     /note="CDR II"
     misc_feature    352..366
                     /note="D-region (aa 99-103)"
     misc_feature    367..>411
                     /note="J-region (aa 104-118)"
BASE COUNT      100 a    104 c    111 g     96 t
ORIGIN
        1 atgaaatgca gctgggtcat gttcttcctg atggcagtgg ttacaggggt caattcagag
       61 gttcagctgc agcagtctgt ggcagagctt gtgaggccag gggcctcagt caggttgtcc
      121 tgcacagctt ctggcttcaa cattaaaaac acctatatgc actgggtgaa gcagaggcct
      181 gaacaaggcc tggagtggat tggaaggatt gatcctgcga atggtaatac taaatatgcc
      241 ccgaagttcc aggtcaaggc cactataaca gcagacacat cctccaacac agcctacctg
      301 cagctcagca gcctgacatc tgaggacact gccatctatt actgtgcccc ttattactac
      361 ggggggtact tcgatgtctg gggcgcaggg accacggtca ctgtttcctc a
//