GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGGNP1 414 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-J (hybridoma 20.1.43) ACCESSION X02562 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 414) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGGNP1; dated 10-JAN-1991. FEATURES Location/Qualifiers CDS join(58..351,352..366,367..414) /product="idiotypic anti-NP IgG(1) heavy chain V-J" /codon_start=58 sig_peptide 1..57 misc_feature 58..351 misc_feature 58..351 /note="variable region (aa 1-98)" misc_feature 148..162 /note="CDR 1" misc_feature 205..255 /note="CDR 2" misc_feature 352..366 misc_feature 352..366 /note="D-region (aa 99-103)" misc_feature 367..>414 /note="J-region (aa 104-119)" BASE COUNT 101 a 98 c 118 g 97 t ORIGIN 1 atgaaatgca gctgggttat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgg ggcagagctt gtgaggccag gggcctcagt caagttgtcc 121 tgcacagctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggcct 181 gaacagggcc tggagtggat tggaaggatt gatcctgcga atggtaatac taaatatgac 241 ccgaagttcc agggcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag ttataggtac 361 gagagggcct ggtttgctta ctggggccaa gggactctgg tcactgtctc tgca //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGGNP2 420 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J (hybridoma 18.1.16) ACCESSION X02563 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 420) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGGNP2; dated 10-JAN-1991. FEATURES Location/Qualifiers mat_peptide join(58..351,352..375,376..420) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" CDS join(1..351,352..375,376..420) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" /codon_start=1 sig_peptide 1..57 misc_feature 58..351 misc_feature 58..351 /note="variable region (aa 1-98)" misc_feature 148..162 /note="CDR I" misc_feature 205..255 /note="CDR II" misc_feature 352..375 misc_feature 352..375 misc_feature 352..375 /note="D-region (aa 99-106)" misc_feature 376..>420 /note="J-region (aa 107-121)" BASE COUNT 107 a 106 c 110 g 97 t ORIGIN 1 atgaaatgca gctgggttat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgg ggcagagctt gtgaagccag gggcctcagt caagttgtcc 121 tgcacggctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggcct 181 gaacagggcc tggagtggat tggaaggatt gatcctgcga atggtaatac taaatatgac 241 ccgaagttcc agggcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag atacctctat 361 tactacggta gtagcgactt tgactactgg ggccaaggca ccactctcac agtctcctca //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGGNP3 414 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J (hybridoma P.5.40.1/group VI) ACCESSION X02564 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 414) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGGNP3; dated 10-JAN-1991. FEATURES Location/Qualifiers mat_peptide join(58..351,352..371,372..414) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" CDS join(1..351,352..371,372..414) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" /codon_start=1 sig_peptide 1..57 misc_feature 58..351 misc_feature 58..351 /note="variable region" misc_feature 148..162 /note="CDR I" misc_feature 205..255 /note="CDR II" misc_feature 352..371 misc_feature 352..371 misc_feature 352..371 /note="D-region (aa 99-105)" misc_feature 372..>414 /note="J-region (aa 106-119)" BASE COUNT 102 a 101 c 111 g 100 t ORIGIN 1 atgaaattca gctgggtcat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgt ggcagagctt gtgaggccag gggcctcagt caagttgtcc 121 tgcacagctt ctggcttcaa cattaaaaac acctatatgc actgggtgaa gcagaggcct 181 gaacagggcc tggagtggat tggaaggatt gatcctgcga atggtagtac taagtatgcc 241 ccgaagttcc agatcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccatctatt actgtgctag gtattactac 361 gagagtagcc tgtttgctta ctggggccaa gggactctgg tcactgtctc tgca //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGGNP6 417 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J (hybridoma P.4.6.1; group V) ACCESSION X02567 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 417) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGGNP6; dated 10-JAN-1991. FEATURES Location/Qualifiers mat_peptide join(58..147,352..>417) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" CDS join(1..147,352..>417) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" /codon_start=1 sig_peptide 1..57 misc_feature 58..147 misc_feature 58..147 /note="V-region (aa 1-98)" misc_feature 148..162 /note="CDR I" misc_feature 205..255 /note="CDR II" misc_feature 352..360 /note="D-region (aa 99-104)" misc_feature 361..>417 /note="J-region (aa 105-120)" BASE COUNT 105 a 100 c 112 g 100 t ORIGIN 1 atgaaatgca gctggatcat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgg ggcagagctt gtgaagccag gggcctcagt caagttgtcc 121 tgcacagctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggact 181 gaacagggcc tggagtggat tggaaggatt gatcctgagg atggtgaaac taaatatgcc 241 ccgaaattcc tgatcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag atacgattat 361 tactacgggt cctggtttgc ttactggggc caagggactc tggtcactgt ctctgca //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGGNP7 414 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J (hybridoma P.4.16.25; group V) ACCESSION X02568 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 414) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C m ice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGGNP7; dated 10-JAN-1991. FEATURES Location/Qualifiers mat_peptide join(58..147,352..414) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" CDS join(1..147,352..414) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" /codon_start=1 sig_peptide 1..57 misc_feature 58..147 misc_feature 58..147 /note="V-region (aa 1-98)" misc_feature 148..162 /note="CDR I" misc_feature 205..255 /note="CDR II" misc_feature 352..365 /note="D-region (aa 99-103)" misc_feature 366..>414 /note="J-region (aa 104-119)" BASE COUNT 107 a 103 c 108 g 96 t ORIGIN 1 atgaaatgca gctggatcat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgg ggcagagctt gtgaggccag gggcctcagt caagttgtcc 121 tgcacagctt ctggcttcaa cattaaagac tactatatgc actgggtgaa gcagaggact 181 gaacagggcc tggagtggat tggaaggatt gatcctgagg atggtgaaac taaatatgcc 241 ccgaaattcc aggtcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag atattactac 361 ggtgctgact actttgacta ctggggccaa ggcaccactc tcacagtctc ctca //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGGNP8 414 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J (hybridoma P.3.6.5) ACCESSION X02569 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 414) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGGNP8; dated 10-JAN-1991. FEATURES Location/Qualifiers mat_peptide join(58..147,352..414) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" CDS join(1..147,352..414) /product="idiotypic anti-NP IgG(1) heavy chain V-D-J" /codon_start=1 sig_peptide 1..57 misc_feature 58..147 misc_feature 58..147 /note="V-region (aa 1-98)" misc_feature 148..162 /note="CDR I" misc_feature 205..255 /note="CDR II" misc_feature 352..372 /note="D-region (aa 99-105)" misc_feature 373..>414 /note="J-region (aa 106-119)" BASE COUNT 102 a 100 c 114 g 98 t ORIGIN 1 atgaaatgca gctggatcat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgg ggcagagctt gtgaggccag gggcctcagt caagtggtcc 121 tgcacggctt ctggcttcaa cattaaagac acctatatgc actgggtgaa gcagaggact 181 gaacagggcc tggagtggat tggaaggatt gatcctgagg atggtgaaac taaatatgcc 241 ccgaaattcc aggtcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccgtctatt actgtgctag ctattactac 361 ggtagtagct tctttgctta ctggggccaa gggactctgg tcactgtctc tgca //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGNP4 411 bp ss-mRNA ROD 27-MAY-1991 DEFINITION Mouse mRNA for idiotypic anti-NP IgG(1) heavy chain V-D-J (hybridoma P.10.15.1/group VI) ACCESSION X02565 KEYWORDS diversity region; gamma-immunoglobulin; immunoglobulin; immunoglobulin heavy chain; joining region; signal peptide; variable region. SOURCE Mus musculus RNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 411) AUTHORS Boersch-Supan,M.E., Agarwal,S., White-Scharf,M.E. and Imanishi-Kari,T. TITLE Heavy chain variable region Multiple gene segments encode anti-4-(hydroxy-3-nitropheny)acetyl idiotypic antibodies JOURNAL J. Exp. Med. 161, 1272-1292 (1985) STANDARD full automatic COMMENT Serological analysis of hybridomaproteins resulting from the immune response to the hapten NP reveals NP(a) idiotypes expressed by Balb/C mice and NP(b) idiotypes expressed by C57 BL/6 mice. The NP(b) family of antibodies consists of 6 subgroups (I-VI) with I-IV sharing more determinants than V and VI which appear quite distinct. From EMBL entry MMIGNP4; dated 16-JAN-1991. FEATURES Location/Qualifiers CDS join(58..411) /product="idiotypic anti-NP IgG(1) heavy chain V-D- J" /codon_start=58 sig_peptide 1..57 misc_feature 58..351 /note="variable region (aa 1-98)" misc_feature 148..162 /note="CDR I" misc_feature 205..255 /note="CDR II" misc_feature 352..366 /note="D-region (aa 99-103)" misc_feature 367..>411 /note="J-region (aa 104-118)" BASE COUNT 100 a 104 c 111 g 96 t ORIGIN 1 atgaaatgca gctgggtcat gttcttcctg atggcagtgg ttacaggggt caattcagag 61 gttcagctgc agcagtctgt ggcagagctt gtgaggccag gggcctcagt caggttgtcc 121 tgcacagctt ctggcttcaa cattaaaaac acctatatgc actgggtgaa gcagaggcct 181 gaacaaggcc tggagtggat tggaaggatt gatcctgcga atggtaatac taaatatgcc 241 ccgaagttcc aggtcaaggc cactataaca gcagacacat cctccaacac agcctacctg 301 cagctcagca gcctgacatc tgaggacact gccatctatt actgtgcccc ttattactac 361 ggggggtact tcgatgtctg gggcgcaggg accacggtca ctgtttcctc a //