GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH81 785 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse DNA germ-line VH81X segment
ACCESSION X01113
KEYWORDS complementarity determining region; immunoglobulin;
immunoglobulin heavy chain; signal peptide.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 785)
AUTHORS Yancopoulos,G.D., Desiderio,S.V., Paskind,M., Kearney,J.F.,
Baltimore,D. and Alt,F.W.
TITLE Preferential utilization of the most JH-proximal VH gene segments
in pre-B-cell lines
JOURNAL Nature 311, 727-733 (1984)
STANDARD full automatic
COMMENT Data kindly reviewed (06-MAR-1986) by F.W. Alt
From EMBL entry MMIGVH81; dated 16-JAN-1991.
FEATURES Location/Qualifiers
sig_peptide join(204..251,383..394)
CDS join(204..251,383..>690)
/product="VH81X segment"
/codon_start=204
misc_feature 1..203
/note="5' flanking region"
intron 252..382
/note="intron"
mat_peptide 395..>690
/product="VH81X segment"
misc_feature 485..499
/note="CDR1 (complementarity determining region) (aa
31-35)"
misc_feature 542..592
/note="CDR2 (aa 50-66)"
misc_feature 691..785
/note="3' flanking region"
misc_feature 691..697
/note="Heptamer-joining signal"
misc_feature 721..729
/note="Nonamer-joining signal"
BASE COUNT 209 a 178 c 183 g 215 t
ORIGIN
1 ggatgtctta tatctatgat gatcactggg ttcagcccag tccggctcca gagcatgcta
61 tagcaggacc acatgcaaat aagccttctc tgtgcccatg aaaaacagct ctgcacttat
121 cctgcagctc tgacagagaa gctcagccct agattctcag gtcctcccat ccagtgatca
181 gaactgaaca gagtccactc gccatggact tcgggctcag cttggttttc cttgtcctta
241 ttttaaaaag taatttatag agatgagatt ctgtctgttg tatgcacttt agaaatagta
301 caaatatttt gtttctttag attctttttt ttatttttat ttatttacgt gacagttttc
361 tgaccagcac tctttgtttg caggtgtaca gtgtgaggtg cagctggtgg agtctggggg
421 aggcttagtg cagcctagag agtccctgaa actctcctgt gaatccaatg aatacgaatt
481 cccttcccat gacatgtctt gggtccgcaa gactccggag aagaggctgg agttggtcgc
541 agccattaat agtgatggtg gtagcaccta ctatccagac accatggaga gacgattcat
601 catctccaga gacaatacca agaagaccct gtacctgcaa atgagcagtc tgaggtctga
661 ggacacagcc ttgtattact gtgcaagaca cacaatgagc aaaagttact gtgagctcaa
721 actaaaacct cctgcagagc atctaggacc agcagggggc gcggagagac acagagttgt
781 gaaat
//