GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH5 451 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germline immunoglobulin V(H)II gene H30
ACCESSION X02458
KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain;
signal peptide; variable region; variable region subgroup VH-II.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 451)
AUTHORS Schiff,C., Milili,M. and Fougereau,M.
TITLE Functional and pseudogenes are similarly organized and may equally
contribute to the extensive antibody diversity of the IgVHII family
JOURNAL EMBO J. 4, 1225-1230 (1985)
STANDARD full automatic
COMMENT From EMBL entry MMIGVH5; dated 02-JUL-1986.
FEATURES Location/Qualifiers
mRNA <1..6
/note="exon 1 fragment"
CDS 1..6
/note="signal peptide fragment (aa -6 to -5) (1 is 2nd
base in codon) (6 is 1st base in codon)"
/codon_start=1
intron 7..89
/note="intron I"
mRNA 90..>89
/note="exon 2 fragment"
CDS 90..100
/note="signal peptide fragment (aa -4 to -1) (90 is 2nd
base in codon)"
/codon_start=90
CDS 101..394
/note="H30 variable region (aa 1-94, kabat numbering)"
/codon_start=101
misc_feature 395..401
/note="rearrangement signal"
misc_feature 425..433
/note="rearrangement signal"
BASE COUNT 129 a 113 c 112 g 97 t
ORIGIN
1 ctgcaggtaa ggggatcacc agttcaaaat ctgaagagga aacagaatct gaggtgacag
61 tgatacctac tatgcctttc tgtccacagg tgtccactcc caggtccagc tgcagcagtc
121 tggggctgaa ctggtcaaga ctggggcctc agtgaagatg tcctgcaagg cttctggcta
181 cacctttact agctacacga tgcactgggt aaaacagagg cctggacagg gtctggaatg
241 gattggatac attaatccta gcagtggtta tactaattac aatcagaagt tcaaggacaa
301 ggccacattg actgcagaca aatcctccag cacagcctac atgcaactga gcagcctgac
361 atctgaggac tctgcagtct attactgtgc aagacacagt ggtgcaacca catcccgact
421 gtgtcacaaa ccctagcaga gcaggaagct t
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH6 469 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germline immunoglobulin V(H)II gene H13-3
ACCESSION X02459
KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain;
signal peptide; variable region; variable region subgroup VH-II.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 469)
AUTHORS Schiff,C., Milili,M. and Fougereau,M.
TITLE Functional and pseudogenes are similarly organized and may equally
contribute to the extensive antibody diversity of the IgVHII family
JOURNAL EMBO J. 4, 1225-1230 (1985)
STANDARD full automatic
COMMENT From EMBL entry MMIGVH6; dated 02-JUL-1986.
FEATURES Location/Qualifiers
mRNA <1..6
/note="exon 1 fragment"
CDS 1..6
/note="signal peptide fragment (aa -6 to -5) (1 is 2nd
base in codon) (6 is 1st base in codon)"
/codon_start=1
intron 7..89
/note="intron I"
mRNA 90..>89
/note="exon 2"
CDS 90..100
/note="signal peptide fragment (aa -4 to -1) (90 is 2nd
base in codon)"
/codon_start=90
CDS 101..394
/note="H13-3 variable region (aa 1-94, kabat numbering)"
/codon_start=101
misc_feature 395..401
/note="rearrangement signal"
misc_feature 425..433
/note="rearrangement signal"
BASE COUNT 137 a 118 c 116 g 98 t
ORIGIN
1 ctgcaggtaa ggggatcacc agttcaaaat ctgaagagga aacagaatct gaggtaacag
61 tgatacctac tatgcctttc tgtccacagg tgtccactcc caggtccagc tgcagcagtc
121 tgcagctgaa ctggcaagac ctggggcctc agtgaagatg tcctgcaagg cttctggcta
181 cacctttact agctacacga tgcactgggt aaaacagagg cctggacagg gtctggaatg
241 gattggatac attaatccta gcagtggata tactgagtac aatcagaagt tcaaggacaa
301 gaccacattg actgcagaca aatcctccag cacagcctac atgcaactga gcagcctgac
361 atctgaggac tctgcggtct attactgtgc aagacacagt ggtgcaacca catcccgact
421 gtgtcagaaa ccctagcaga acaggaagct tacctgggac tgagaattc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH7 676 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germline immunoglobulin V(H)II pseudogene H24
ACCESSION X02460
KEYWORDS enhancer; germline; immunoglobulin; immunoglobulin heavy chain;
pseudogene; signal peptide; variable region;
variable region subgroup VH-II.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 676)
AUTHORS Schiff,C., Milili,M. and Fougereau,M.
TITLE Functional and pseudogenes are similarly organized and may equally
contribute to the extensive antibody diversity of the IgVHII family
JOURNAL EMBO J. 4, 1225-1230 (1985)
STANDARD full automatic
COMMENT From EMBL entry MMIGVH7; dated 16-JAN-1991.
FEATURES Location/Qualifiers
sig_peptide join(147..192,276..286)
CDS join(147..192,276..580)
/note="(aa 1-94, kabat numbering)"
/product="H24 variable region"
/codon_start=147
misc_feature 40..49
/note="sequence homologous to SV40 enhancer"
promoter 67..72
/note="pot. TATA-box"
precursor_RNA 95..>94
/note="pot. H24 primary transcript"
mRNA 95..194
/note="pot. H24 mRNA; exon 1"
misc_RNA 95..95
/note="put. CAP site"
intron 193..275
/note="intron I"
mRNA 276..>275
/note="H24 mRNA; exon 2"
mat_peptide 287..580
/note="(aa 1-94, kabat numbering)"
/product="H24 variable region"
misc_feature 530..532
/note="in frame stop codon of pseudogene"
misc_feature 581..587
/note="recombination signal"
misc_feature 611..619
/note="recombination signal"
BASE COUNT 174 a 168 c 168 g 166 t
ORIGIN
1 tggactagat ccttactaag taatgcactg ctcatgaata tgcaaatcac gcaagtcttt
61 ggcagtaaat actgggatgt ccacaccctg aaaacaacct aagatcagtg tcctctccac
121 agtccctgaa cacactgact ttcaccatgg aatggagcgg ggtctttatc tttctcctgt
181 cagtaactgc aggtaagggg ctccccattt ccaaatctga agatgataca gggcctgagg
241 tgacaatgcc aaccactctg cctttctctc cacaggtgtc cactcgcagg tccagctgca
301 gcagtctgga gctgagctgg taaggcctgg gacttcagtg aagaagtcct gcaaggtttc
361 tggatacacc ttcgctaact actggatagg ttgggtaaag cagaggcctg gacatggcct
421 tgagtggatt ggagatattt accctggaga cggtgttact aactacaatg agaagttcaa
481 gggcaaggcc acactgactg cagacaaatc ctccagcaca gcctacatgt agctcagcag
541 cctgacatct gaggactctg cggtctatta ctgttcgaga cacagtgttg caaccacatc
601 ctgagtgtgt cagaaaccct ggaggagtag caaactgccc tgggtctgag ttgtctcagt
661 gaaggtttct ttgtag
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH8 377 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germline immunoglobulin V(H)II gene H16
ACCESSION X02461
KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain;
signal peptide; variable region; variable region subgroup VH-II.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 377)
AUTHORS Schiff,C., Milili,M. and Fougereau,M.
TITLE Functional and pseudogenes are similarly organized and may equally
contribute to the extensive antibody diversity of the IgVHII family
JOURNAL EMBO J. 4, 1225-1230 (1985)
STANDARD full automatic
COMMENT From EMBL entry MMIGVH8; dated 02-JUL-1986.
FEATURES Location/Qualifiers
mRNA <1..6
/note="exon 1 fragment"
CDS 1..6
/note="pot. signal peptide (aa -6 to -5) (1 is 2nd base in
codon) (6 is 1st base in codon)"
/codon_start=1
intron 7..89
/note="intron I"
mRNA 90..>89
/note="H16 mRNA; exon 2"
CDS 90..100
/note="pot. signal peptide (aa -4 to -1) (90 is 2nd base
in codon)"
/codon_start=90
CDS 101..377
/note="H16 variable region (aa 1-88/kabat numbering) (377
is 1st base in codon)"
/codon_start=101
BASE COUNT 101 a 96 c 92 g 88 t
ORIGIN
1 ctgcaggtaa ggggctcacc atttccaaat ctgaagaaaa gaaatggctt gtgatgtcac
61 tgacatccac tctgtctttc tctcctcagg cgtccactct gaggtccagc ttcagcagtc
121 aggacctgag ctggtgaaac ctggggcctc agtgaagata tcctgcaagg cttctggata
181 cacattcact gactacaaca tgcactgggt gaagcagagc catggaaaga gccttgagtg
241 gattggatat atttatcctt acaatggtgg tactggctac aaccagaagt tcaagagcaa
301 ggccacattg actgtagaca attcctccag cacagcctac atggacgtcc gcagcctgac
361 atctgaggac tctgcag
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH9 653 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse germline immunoglobulin V(H)II pseudogene H26-1
ACCESSION X02462
KEYWORDS enhancer; germline; immunoglobulin; immunoglobulin heavy chain;
pseudogene; signal peptide; variable region;
variable region subgroup VH-II.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 653)
AUTHORS Schiff,C., Milili,M. and Fougereau,M.
TITLE Functional and pseudogenes are similarly organized and may equally
contribute to the extensive antibody diversity of the IgVHII family
JOURNAL EMBO J. 4, 1225-1230 (1985)
STANDARD full automatic
COMMENT From EMBL entry MMIGVH9; dated 16-JAN-1991.
FEATURES Location/Qualifiers
sig_peptide join(124..169,253..263)
CDS join(124..169,253..557)
/note="(aa 1- 94, kabat numbering)"
/product="pot. H26-1 variable region"
/codon_start=124
misc_feature 16..25
/note="sequence homologous to SV40 enhancer"
promoter 43..49
/note="pot. TATA-box"
precursor_RNA 72..>71
/note="put. H26-1 primary transcript"
mRNA 72..169
/note="pot. H26-1 mRNA; exon 1"
misc_RNA 72..72
/note="put. CAP-site"
misc_feature 124..126
/note="mutated start codon of pseudogene"
intron 170..252
/note="pot. intron I"
mRNA 253..>252
/note="pot. H26-1 mRNA; exon 2"
mat_peptide 264..557
/note="(aa 1- 94, kabat numbering)"
/product="pot. H26-1 variable region"
misc_feature 558..564
/note="recombination signal"
misc_feature 588..596
/note="recombination signal"
BASE COUNT 185 a 156 c 150 g 162 t
ORIGIN
1 ggcctgctca tgaatatgca tattacctgt gtctatgttg gttaaaaaca gggatatcaa
61 caccctgaaa accacatatg tccaatgtcc tctccatagt cccttaacac actgactcta
121 accataaaat ggagctggat ctttctcttc ctcctgtcag gaactgcacg taaggggctc
181 accagttcca aatctgaaga aagaaaatat cctaagatgt caatgacaac cactctgtct
241 ttcttttcac aggtgtccac tctgaggtcc agctgcagca gtctggacct gagctggtga
301 agctggggcc ttcagtgaag atatcctgca aggcttctgg ttactcattc actggctact
361 acatgcactg ggtgaagcag agccatggaa agagccttga gtggattgga gaaattaatc
421 cttacaatgg tggtactagc tacaaccaga agttcaaggg caaggccaca ttgactgtag
481 acacatcctc cagcacagcg tacatggagc tccacagcct gacatctgag gactctttgg
541 tctattactg tgcaagacac agtgttgtaa ccacagcctg agtgtgtcag aaaactggaa
601 ggtgcagcaa ggtgccttga gactgacaag acttagagaa cagtagcttg tag
//