GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH5 451 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II gene H30 ACCESSION X02458 KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 451) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH5; dated 02-JUL-1986. FEATURES Location/Qualifiers mRNA <1..6 /note="exon 1 fragment" CDS 1..6 /note="signal peptide fragment (aa -6 to -5) (1 is 2nd base in codon) (6 is 1st base in codon)" /codon_start=1 intron 7..89 /note="intron I" mRNA 90..>89 /note="exon 2 fragment" CDS 90..100 /note="signal peptide fragment (aa -4 to -1) (90 is 2nd base in codon)" /codon_start=90 CDS 101..394 /note="H30 variable region (aa 1-94, kabat numbering)" /codon_start=101 misc_feature 395..401 /note="rearrangement signal" misc_feature 425..433 /note="rearrangement signal" BASE COUNT 129 a 113 c 112 g 97 t ORIGIN 1 ctgcaggtaa ggggatcacc agttcaaaat ctgaagagga aacagaatct gaggtgacag 61 tgatacctac tatgcctttc tgtccacagg tgtccactcc caggtccagc tgcagcagtc 121 tggggctgaa ctggtcaaga ctggggcctc agtgaagatg tcctgcaagg cttctggcta 181 cacctttact agctacacga tgcactgggt aaaacagagg cctggacagg gtctggaatg 241 gattggatac attaatccta gcagtggtta tactaattac aatcagaagt tcaaggacaa 301 ggccacattg actgcagaca aatcctccag cacagcctac atgcaactga gcagcctgac 361 atctgaggac tctgcagtct attactgtgc aagacacagt ggtgcaacca catcccgact 421 gtgtcacaaa ccctagcaga gcaggaagct t //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH6 469 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II gene H13-3 ACCESSION X02459 KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 469) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH6; dated 02-JUL-1986. FEATURES Location/Qualifiers mRNA <1..6 /note="exon 1 fragment" CDS 1..6 /note="signal peptide fragment (aa -6 to -5) (1 is 2nd base in codon) (6 is 1st base in codon)" /codon_start=1 intron 7..89 /note="intron I" mRNA 90..>89 /note="exon 2" CDS 90..100 /note="signal peptide fragment (aa -4 to -1) (90 is 2nd base in codon)" /codon_start=90 CDS 101..394 /note="H13-3 variable region (aa 1-94, kabat numbering)" /codon_start=101 misc_feature 395..401 /note="rearrangement signal" misc_feature 425..433 /note="rearrangement signal" BASE COUNT 137 a 118 c 116 g 98 t ORIGIN 1 ctgcaggtaa ggggatcacc agttcaaaat ctgaagagga aacagaatct gaggtaacag 61 tgatacctac tatgcctttc tgtccacagg tgtccactcc caggtccagc tgcagcagtc 121 tgcagctgaa ctggcaagac ctggggcctc agtgaagatg tcctgcaagg cttctggcta 181 cacctttact agctacacga tgcactgggt aaaacagagg cctggacagg gtctggaatg 241 gattggatac attaatccta gcagtggata tactgagtac aatcagaagt tcaaggacaa 301 gaccacattg actgcagaca aatcctccag cacagcctac atgcaactga gcagcctgac 361 atctgaggac tctgcggtct attactgtgc aagacacagt ggtgcaacca catcccgact 421 gtgtcagaaa ccctagcaga acaggaagct tacctgggac tgagaattc //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH7 676 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II pseudogene H24 ACCESSION X02460 KEYWORDS enhancer; germline; immunoglobulin; immunoglobulin heavy chain; pseudogene; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 676) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH7; dated 16-JAN-1991. FEATURES Location/Qualifiers sig_peptide join(147..192,276..286) CDS join(147..192,276..580) /note="(aa 1-94, kabat numbering)" /product="H24 variable region" /codon_start=147 misc_feature 40..49 /note="sequence homologous to SV40 enhancer" promoter 67..72 /note="pot. TATA-box" precursor_RNA 95..>94 /note="pot. H24 primary transcript" mRNA 95..194 /note="pot. H24 mRNA; exon 1" misc_RNA 95..95 /note="put. CAP site" intron 193..275 /note="intron I" mRNA 276..>275 /note="H24 mRNA; exon 2" mat_peptide 287..580 /note="(aa 1-94, kabat numbering)" /product="H24 variable region" misc_feature 530..532 /note="in frame stop codon of pseudogene" misc_feature 581..587 /note="recombination signal" misc_feature 611..619 /note="recombination signal" BASE COUNT 174 a 168 c 168 g 166 t ORIGIN 1 tggactagat ccttactaag taatgcactg ctcatgaata tgcaaatcac gcaagtcttt 61 ggcagtaaat actgggatgt ccacaccctg aaaacaacct aagatcagtg tcctctccac 121 agtccctgaa cacactgact ttcaccatgg aatggagcgg ggtctttatc tttctcctgt 181 cagtaactgc aggtaagggg ctccccattt ccaaatctga agatgataca gggcctgagg 241 tgacaatgcc aaccactctg cctttctctc cacaggtgtc cactcgcagg tccagctgca 301 gcagtctgga gctgagctgg taaggcctgg gacttcagtg aagaagtcct gcaaggtttc 361 tggatacacc ttcgctaact actggatagg ttgggtaaag cagaggcctg gacatggcct 421 tgagtggatt ggagatattt accctggaga cggtgttact aactacaatg agaagttcaa 481 gggcaaggcc acactgactg cagacaaatc ctccagcaca gcctacatgt agctcagcag 541 cctgacatct gaggactctg cggtctatta ctgttcgaga cacagtgttg caaccacatc 601 ctgagtgtgt cagaaaccct ggaggagtag caaactgccc tgggtctgag ttgtctcagt 661 gaaggtttct ttgtag //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH8 377 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II gene H16 ACCESSION X02461 KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 377) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH8; dated 02-JUL-1986. FEATURES Location/Qualifiers mRNA <1..6 /note="exon 1 fragment" CDS 1..6 /note="pot. signal peptide (aa -6 to -5) (1 is 2nd base in codon) (6 is 1st base in codon)" /codon_start=1 intron 7..89 /note="intron I" mRNA 90..>89 /note="H16 mRNA; exon 2" CDS 90..100 /note="pot. signal peptide (aa -4 to -1) (90 is 2nd base in codon)" /codon_start=90 CDS 101..377 /note="H16 variable region (aa 1-88/kabat numbering) (377 is 1st base in codon)" /codon_start=101 BASE COUNT 101 a 96 c 92 g 88 t ORIGIN 1 ctgcaggtaa ggggctcacc atttccaaat ctgaagaaaa gaaatggctt gtgatgtcac 61 tgacatccac tctgtctttc tctcctcagg cgtccactct gaggtccagc ttcagcagtc 121 aggacctgag ctggtgaaac ctggggcctc agtgaagata tcctgcaagg cttctggata 181 cacattcact gactacaaca tgcactgggt gaagcagagc catggaaaga gccttgagtg 241 gattggatat atttatcctt acaatggtgg tactggctac aaccagaagt tcaagagcaa 301 ggccacattg actgtagaca attcctccag cacagcctac atggacgtcc gcagcctgac 361 atctgaggac tctgcag //
GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVH9 653 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II pseudogene H26-1 ACCESSION X02462 KEYWORDS enhancer; germline; immunoglobulin; immunoglobulin heavy chain; pseudogene; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 653) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH9; dated 16-JAN-1991. FEATURES Location/Qualifiers sig_peptide join(124..169,253..263) CDS join(124..169,253..557) /note="(aa 1- 94, kabat numbering)" /product="pot. H26-1 variable region" /codon_start=124 misc_feature 16..25 /note="sequence homologous to SV40 enhancer" promoter 43..49 /note="pot. TATA-box" precursor_RNA 72..>71 /note="put. H26-1 primary transcript" mRNA 72..169 /note="pot. H26-1 mRNA; exon 1" misc_RNA 72..72 /note="put. CAP-site" misc_feature 124..126 /note="mutated start codon of pseudogene" intron 170..252 /note="pot. intron I" mRNA 253..>252 /note="pot. H26-1 mRNA; exon 2" mat_peptide 264..557 /note="(aa 1- 94, kabat numbering)" /product="pot. H26-1 variable region" misc_feature 558..564 /note="recombination signal" misc_feature 588..596 /note="recombination signal" BASE COUNT 185 a 156 c 150 g 162 t ORIGIN 1 ggcctgctca tgaatatgca tattacctgt gtctatgttg gttaaaaaca gggatatcaa 61 caccctgaaa accacatatg tccaatgtcc tctccatagt cccttaacac actgactcta 121 accataaaat ggagctggat ctttctcttc ctcctgtcag gaactgcacg taaggggctc 181 accagttcca aatctgaaga aagaaaatat cctaagatgt caatgacaac cactctgtct 241 ttcttttcac aggtgtccac tctgaggtcc agctgcagca gtctggacct gagctggtga 301 agctggggcc ttcagtgaag atatcctgca aggcttctgg ttactcattc actggctact 361 acatgcactg ggtgaagcag agccatggaa agagccttga gtggattgga gaaattaatc 421 cttacaatgg tggtactagc tacaaccaga agttcaaggg caaggccaca ttgactgtag 481 acacatcctc cagcacagcg tacatggagc tccacagcct gacatctgag gactctttgg 541 tctattactg tgcaagacac agtgttgtaa ccacagcctg agtgtgtcag aaaactggaa 601 ggtgcagcaa ggtgccttga gactgacaag acttagagaa cagtagcttg tag //