GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSIGVNP1 606 bp ds-DNA ROD 27-MAY-1991
DEFINITION Mouse genomic DNA fragment of 4 hydroxyl-3-nitrophenacetyl (NP)
specific IgM immunoglobulin heavy chain leader and variable region
(VNP)
ACCESSION X01832
KEYWORDS immunoglobulin; immunoglobulin heavy chain; mu-immunoglobulin;
signal peptide; variable region.
SOURCE Mus musculus DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 606)
AUTHORS Neuberger,M.S.
TITLE Expression and regulation of immunoglobulin heavy chain gene
transfected into lymphoid cells
JOURNAL EMBO J. 2, 1373-1378 (1983)
STANDARD full automatic
COMMENT EPD; 14073; Mm Ig V_NP P1. EPD; 14074; Mm Ig V_NP P2+.
Data kindly reviewed (11-FEB-1986) by M.S. Neuberger
From EMBL entry MMIGVNP1; dated 16-JAN-1991.
FEATURES Location/Qualifiers
sig_peptide join(342..387,470..480)
CDS join(342..387,470..>606)
/product="VNP"
/codon_start=342
promoter 236..240
/note="pot. CAAT-site"
promoter 258..264
/note="pot. TATA-box"
promoter 274..277
/note="pot. TATA-box"
precursor_RNA 280..>606
/note="VNP primary transcript"
mRNA 280..387
/note="exon 1"
misc_RNA 280..280
/note="pot. cap site"
misc_RNA 302..302
/note="pot. alternative cap site"
intron 388..469
/note="intron I"
mRNA 470..>606
mRNA 470..>606
/note="exon 2"
mat_peptide 481..>606
/product="VNP"
BASE COUNT 157 a 142 c 149 g 158 t
ORIGIN
1 aactgtgtta cagtggggcc actgtctcag gatgcaaatc tttttagtgg acaggctcta
61 atgttacatc tatagcctca acacaaagtt cagggatgag gtatgaggta tgaggatgaa
121 tttccacaga gaagattagg actggggctt cagaatcctg attcctgacc caggtgtccc
181 ttcttctcca gcaggagtag gtgttcatct aatatgtatc ctgctcatga atatgcaaat
241 cctctgaatc tacatggtaa atataggttt gtctatacca caaacagaaa aacatgagat
301 cacagttctc tctacagtta ctgagcacac aggacctcac catgggatgg agctgtatca
361 tcctcttctt ggtagcaaca gctacaggta aggggctcac agtagcaggc ttgaggtctg
421 gacatatata tgggtgacaa tgacatccac tttgcctttc tctccacagg tgtccactcc
481 caggtccaac tgcagcagcc tggggctgag cttgtgaagc ctggggcttc agtgaagctg
541 tcctgcaagg cttctggcta caccttcacc agctactgga tgcactgggt gaagcagagg
601 cctgga
//