GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSTCRA26 282 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse nonproductive mRNA for T-cell receptor alpha chain (TA26)
ACCESSION X02930
KEYWORDS T-cell receptor; T-cell receptor alpha; constant region;
joining region; signal peptide; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 282)
AUTHORS Arden,B., Klotz,J.L., Siu,G. and Hood,L.
TITLE Diversity and structure of genes of the alpha family of mouse
T-cell antigen receptor
JOURNAL Nature 316, 783-787 (1985)
STANDARD full automatic
COMMENT *source: strain=C57Bl/Ka; clone=TA26; tissue=thymus; Except the
frameshifting deletion the sequence is nearly identical to that of
clone pHD558 described in Saito, H. et al., Nature 312,
136-140(1984). The deletion is thought to be a cloning artefact or
indicates a rearranged and transcribed pseudogene.
From EMBL entry MMTCRA26; dated 02-APR-1988.
FEATURES Location/Qualifiers
CDS 1..60
/note="put. signal peptide"
/codon_start=1
CDS 61..213
/note="put. V(alpha) 3 segment (pot. aa 1-34 and 78-94)"
/codon_start=61
misc_feature 162..163
/note="deletion site causing frame shift"
CDS 214..216
/note="put. junctional diversity region"
/codon_start=214
CDS 217..277
/note="put. J(alpha) segment (277 is 1st base in codon)"
/codon_start=217
CDS 278..>282
/note="C(alpha) segment (278 is 2nd base in codon)"
/codon_start=278
BASE COUNT 62 a 77 c 72 g 71 t
ORIGIN
1 atgctcctgg cgctcctccc agtgctgggg atacactttg tcctgagaga tgcccaagct
61 cagtcagtga cacagcccga tgctcgcgtc actgtctctg aaggagcctc tctgcagctg
121 agatgcaagt attcctactc tgcgacacct tatctgttct gaaaagcctc tgtgcactgg
181 agcgactcgg ctgtgtactt ctgtgctctc ccgaatactg gaggactaag tggtaaatta
241 acattcgggg aagggaccca agtgacggta atatctgaca tc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSTCRA27 427 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse nonproductive mRNA for T-cell receptor alpha chain (TA27)
ACCESSION X02935
KEYWORDS T-cell receptor; T-cell receptor alpha; constant region;
joining region; signal peptide; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 427)
AUTHORS Arden,B., Klotz,J.L., Siu,G. and Hood,L.
TITLE Diversity and structure of genes of the alpha family of mouse
T-cell antigen receptor
JOURNAL Nature 316, 783-787 (1985)
STANDARD full automatic
COMMENT *source: clone=TA27; strain=C57Bl/Ka; The V-J rearrangement shifts
the J-sequence out of the correct reading frame, the transcript is
thought to be nonproductive.
From EMBL entry MMTCRA27; dated 02-APR-1988.
FEATURES Location/Qualifiers
CDS 1..63
/note="put. signal peptide (aa -21 to -1)"
/codon_start=1
CDS 64..345
/note="put. V(alpha) 7 segment (aa 1-94)"
/codon_start=64
misc_feature 346..358
/note="frameshifting junctional region"
CDS 359..413
/note="put. J(alpha) segment"
/codon_start=359
CDS 414..>427
/note="C(alpha) segment"
/codon_start=414
BASE COUNT 106 a 103 c 104 g 114 t
ORIGIN
1 atgcctcctc acagcctgtt ctgtgtgctg gtggccttgc gtttctctgg atctaatgtg
61 gccgagaaag tgattcaggt ctggtcaaca gcaagcaggc aggagggcga agaactcacc
121 ctggactgtt catatgagac aagtcaggtc ttataccatc ttttctggta caagcacctt
181 cttagtggag agatggtttt ccttattcga caaacgtctt cttctactgc aaaagagagg
241 agcggccgct attctgtagt cttccagaaa tcactcaaat ccatcagcct tatcatttca
301 gctttacaac cagacgattc gggaaagtat ttctgtgctc tctgggagct ccaatcaagg
361 agggtctgcg aagctcatct ttggggaggg gacaaagctg acagtgagct catacatcca
421 gaaccca
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSTCRA31 398 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse nonproductive mRNA for T-cell receptor alpha chain (TA31)
ACCESSION X02928
KEYWORDS T-cell receptor; T-cell receptor alpha; constant region;
joining region; signal peptide; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 398)
AUTHORS Arden,B., Klotz,J.L., Siu,G. and Hood,L.
TITLE Diversity and structure of genes of the alpha family of mouse
T-cell antigen receptor
JOURNAL Nature 316, 783-787 (1985)
STANDARD full automatic
COMMENT *source: clone=TA31; strain=C57Bl/Ka; tissue=thymus; The V-J
rearrangement shifts the J-sequence out of the correct reading
frame, the transcript is thought to be nonproductive.
From EMBL entry MMTCRA31; dated 02-APR-1988.
FEATURES Location/Qualifiers
CDS 1..54
/note="put. signal peptide (aa -18 to -1)"
/codon_start=1
CDS 55..324
/note="put. V(alpha) 1 segment"
/codon_start=55
misc_feature 325..341
/note="put. frameshifting junctional region"
CDS 342..393
/note="put. J(alpha) segment"
/codon_start=342
CDS 394..>398
/note="C(alpha) segment"
/codon_start=394
BASE COUNT 107 a 106 c 92 g 93 t
ORIGIN
1 ttgagtgttt tactagtggt cctgtggctc cagttaaact gcgtgaggag ccagcagaag
61 gtgcagcaga gcccagaatc cctcagtgtc ccagagagca tggcctctct caactgcact
121 tcaagtgatc gtaattttca gtacttctgg tggtacagac agcattctgg agaaggcccc
181 aaggcactga tgtccatctt ctctgatggt gacaagaaag aaggcagatt cacagctcac
241 ctcaataagg ccagcctgca tgtttccctg cacatcagag actcccagcc cagtgactcc
301 gctctctact tctgtgcagc tagtgagcat gagccaacta tggaaatgag aaaataactt
361 ttggggctgg aaccaaactc accattaaac ccaacatc
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSTCRA37 191 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse nonproductive mRNA for T-cell receptor alpha chain (TA37)
ACCESSION X02937
KEYWORDS T-cell receptor; T-cell receptor alpha; constant region;
joining region; pseudogene; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 191)
AUTHORS Arden,B., Klotz,J.L., Siu,G. and Hood,L.
TITLE Diversity and structure of genes of the alpha family of mouse
T-cell antigen receptor
JOURNAL Nature 316, 783-787 (1985)
STANDARD full automatic
COMMENT *source: clone=TA37; strain=C57Bl/Ka; The frameshifting single base
deletion in the V(alpha) segment indicates that the sequence
represents probably a transcript derived from the rearrangement of
pseudogenes. The 3' end of V(alpha) segment was determined
referring to germline V(alpha) 5H gene segment (see X02833). The 5'
end of the J(alpha) segment was determined by assuming that it
begins one codon after the end of the V(alpha) segment.
From EMBL entry MMTCRA37; dated 02-APR-1988.
FEATURES Location/Qualifiers
CDS <1..119
/note="put. V(alpha) 9 segment"
/codon_start=1
misc_feature 91..92
/note="single base deletion site causing frameshift"
CDS 120..122
/note="put. junctional diversity region"
/codon_start=120
CDS 123..177
/note="put. J(alpha) segment"
/codon_start=123
CDS 178..>191
/note="C(alpha) segment"
/codon_start=178
BASE COUNT 51 a 43 c 53 g 44 t
ORIGIN
1 ggaaatgtgc aaagagctgc gacgttcctt agtgactgtg gtggatgtca gtcttccagt
61 gtgctttgtc ccagaaggat tggacaacag gctcaggcac ttatctctgt gctatgaata
121 ataatgcagg tgccaagctc acattcggag ggggaacaag gttaacggtc agacccgaca
181 tccagaaccc a
//GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS MUSTCRA80 293 bp ss-mRNA ROD 27-MAY-1991
DEFINITION Mouse nonproductive mRNA for T-cell receptor alpha chain (TA80)
ACCESSION X02939
KEYWORDS T-cell receptor; T-cell receptor alpha; constant region;
joining region; variable region.
SOURCE Mus musculus RNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 293)
AUTHORS Arden,B., Klotz,J.L., Siu,G. and Hood,L.
TITLE Diversity and structure of genes of the alpha family of mouse
T-cell antigen receptor
JOURNAL Nature 316, 783-787 (1985)
STANDARD full automatic
COMMENT *source: strain=C57Bl/Ka; clone=TA80; The substitution changing the
put. important cys residue and the frameshifting V-J rearrangement
indicate that the sequence is probably a transcript derived from
rearrangement of pseudogenes. The 3' end of V(alpha) segment was
determined referring to germline V(alpha) 5H gene segment (see
X02833). The 5' end of J(alpha) segment was determined in
comparison to corresponding germline segment (see X02859).
From EMBL entry MMTCRA80; dated 02-APR-1988.
FEATURES Location/Qualifiers
CDS <1..219
/note="put. V(alpha) 5 segment (put. aa 20-93)"
/codon_start=1
misc_feature 7..9
/note="put. substitution site changing cys to ala"
misc_feature 220..224
/note="frameshifting junctional region"
CDS 225..282
/note="J(alpha) segment"
/codon_start=225
CDS 283..>293
/note="C(alpha) segment"
/codon_start=283
BASE COUNT 90 a 78 c 64 g 61 t
ORIGIN
1 ataacggcac cctacacaga ccctaacagt tattacttct tctggtacaa gcaagagccg
61 ggggcaagtc ttcagttgct tatgaaggtt ttctcaagta cggaaataaa cgaaggacaa
121 ggattcactg tcctactgaa caagaaagac aaacgactct ctctgaacct cacagctgcc
181 catcctgggg actcagccgc gtacttctgc gcagtcagtg aaagacagaa ggtgcagata
241 gactcacctt tgggaaagga actcagctga tcatccagcc ctacatccag aac
//