GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS RATALPHPR 852 bp ds-DNA ROD 27-MAY-1991
DEFINITION Rat bone/liver/kidney alkaline phosphatase gene promoter and exon 1
region
ACCESSION X07768
KEYWORDS alkaline phosphatase.
SOURCE Rattus norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 852)
AUTHORS Zernik,J.
JOURNAL Unpublished (1988)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Zernik,J., Thiede,M.A., Twarog,K., Stover,M.L., Rodan,G.A.,
Upholt,W.B. and Rowe,D.W.
TITLE Cloning and analysis of the 5' region of the rat bone/liver/kidney
/placenta alkaline phosphatase gene. A dual function promoter
JOURNAL Matrix 10, 38-47 (1990)
STANDARD full staff_review
COMMENT *source: strain=Sprague-Dawley; library=lambda Charon 4A; *source:
clone=RAP114.
From EMBL entry RNALPHPR; dated 05-JUL-1990.
FEATURES Location/Qualifiers
promoter 454..463
/note="two overlapping SP1 binding sites"
promoter complement(473..486)
/note="SP1 binding site"
precursor_RNA 504..>852
/note="transcript"
promoter 504..510
/note="TATA-box"
mRNA 546..613
/note="exon 1"
BASE COUNT 169 a 263 c 292 g 128 t
ORIGIN
1 cccgggtcag gtcctggggc ctctgactgg gacagacaga atgtcctgag tccctatttc
61 tgaaggcatt agggagggaa ggccctgccg gagggatctc cctctgcttc ctactgactt
121 cgctaagggc gaaaaagaaa gtggctagga aaggggtaag ggtgagaggg ctcagaggcg
181 tacatggtta cagacaagga tgtctaggca gaaagataga gacttaagag aagccaagtg
241 gattcataga cgcgccagtt caggcacagg aaaacaacca tcaagggaca aacattccta
301 cagagaaact caaacctaac gacgccagcc ctaggccagg atgagcaagg gcgctaacct
361 gcctgtgcca gtacgggccg ggtcagggcc ggctcccggc agggggcgcc ctggcaacgc
421 agagcaccag cctggggctc cgggtgcggg ccggggcggg cggccggggg cggggaggcc
481 ggcgggtgct cagccgggcc gccttcataa gcaggcgggg aaggtggccg ccagagtagc
541 tcgcccacgg cgctccttag ggccagccct cggcgcgccg ggacagaccc tccccactcc
601 tgcctgcctg caggtaagga aagcatgctg cgcccgcggc tggtgcgact ctcacgcgcg
661 cgctccgccg gtcccgtagt gactgtccca gccactgtgg ggaacgtgga aggtcaggct
721 ccctggggac tcacgacctc ccgctccgga ccccgcgtgc atctcttggg gcctggctgg
781 atgacggtcg tgtcgcccgc ggagccgcta ctcaggaccc taccctggtg ctaagccatg
841 ctcccggtgc cc
//