GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS HS1HSV1G3 6633 bp ds-DNA VRL 28-MAY-1991
DEFINITION Herpes simplex virus type I immediate early (IE) gene 3 for
transcriptional activator IE175 (= ICP 4)
ACCESSION X06461
KEYWORDS IE gene 3; IE175 protein; IE68 protein; origin of replication;
transcriptional activator.
SOURCE Herpes simplex virus type 1 DNA.
ORGANISM Herpes simplex virus type 1
Viridae; ds-DNA enveloped viruses; Herpesviridae;
Alphaherpesvirinae.
REFERENCE 1 (bases 1 to 6633)
AUTHORS Mcgeoch,D.J., Dolan,A., Donald,S. and Brauer,D.H.
TITLE Complete DNA sequence of the short repeat region in the genome of
herpes simplex virus type 1
JOURNAL Nucleic Acids Res. 14, 1727-1745 (1986)
STANDARD full automatic
COMMENT SWISS-PROT; P08392; IE17$HSV11.
*source: strain=17; **map: R(s) region;
From EMBL entry HEHSV1G3; dated 21-OCT-1988.
FEATURES Location/Qualifiers
mRNA complement(<1..64)
/note="Exon 1 IE68"
precursor_RNA complement(<1..479)
/note="primary transcript of IE68 gene"
intron complement(65..232)
/note="Intron I"
misc_feature complement(113..217)
/note="repetitious region 1"
mRNA complement(233..479)
/note="Exon 2 IE68"
promoter complement(502..509)
/note="TATA-Box (IE68 gene)"
rep_origin 597..663
/note="origin of replication"
promoter 1148..1154
/note="TATA-Box (IE3 gene)"
mRNA 1176..5435
/note="IE175 mRNA"
CDS 1477..5370
/note="IE175 (ICP4) transcriptional activator (AA 1 -
1298)"
/codon_start=1477
misc_feature 5416..5421
/note="polyA signal"
polyA_site 5435..5435
/note="polyA site"
misc_feature 5463..5795
/note="repetitious region 2"
misc_feature 5897..6034
/note="repetitious region 3"
misc_feature 6232..>6231
/note="a' sequence"
misc_feature 6332..6554
/note="repetitious region 4"
BASE COUNT 685 a 2453 c 2818 g 677 t
ORIGIN
1 cccgacgagc aggaagcggt ccacgcaacg gtcgccgccg gtcgcctcga cgaggacgtt
61 cctcctgcgg gaaggcacga acgcgggtga gccccctcct ccgcccccgc gtcccccctc
121 ctccgccccc gcgtcccccc tcctccgccc ccgcgtcccc cctcctccgc ccccgcgtcc
181 cccctcctcc gcccccgcgt ccccccctcc tccgcccacc caaggtgctt acccgtgcaa
241 aaaaggcgga ccggtgggtt tctgtcgtcg gaggcccccg gggtgcgtcc cctgtgtttc
301 gtgggtgggg tgggcgggtc tttccccccc gcgtccgcgt gtccctttcc gatgcgatcc
361 cgatcccgag ccggggcgtc gcgatgccga cgccgtccgc tccgacggcc ctctgcgact
421 cccgctcccg gtccgcgtgc tccgcagccg ctcccgtcgt tcgtggccgg cgccgtctgc
481 gggcgtcggt cgcgccgggc ctttatgtgc gccggagaga cccgcccccc gccgcccggg
541 cccgcccccg gggccggcgc ggagtcgggc acggcgccag tgctcgcact tcgccctaat
601 aatatatata tattgggacg aagtgcgaac gcttcgcgtt ctcacttctt ttacccggcg
661 gccccgcccc cttggggcgg tcccgcccgc cggccaatgg gggggcggca aggcgggcgg
721 cccttgggcc gcccgccgtc ccgttggtcc cggcgtccgg cgggcgggac cggggggccc
781 ggggacggcc aacgggcgcg cggggctcgt atctcattac cgccgaaccg ggaagtcggg
841 gcccgggccc cgccccctgc ccgttcctcg ttagcatgcg gaacggaagc ggaaaccgcc
901 ggatcgggcg gtaatgagat gccatgcggg gcggggcgcg gacccacccg ccctcgcgcc
961 ccgcccatgg cagatggcgc ggatgggcgg ggccgggggt tcgaccaacg ggccgcggcc
1021 acgggccccc ggcgtgccgg cgtcggggcg gggtcgtgca taatggaatt ccgttcgggg
1081 tgggcccgcc gggggggcgg ggggccggcg gcctccgctg ctcctccttc ccgccggccc
1141 ctgggactat atgagcccga ggacgccccg atcgtccaca cggagcgcgg ctgccgacac
1201 ggatccacga cccgacgcgg gaccgccaga gacagaccgt cagacgctcg ccgcgccggg
1261 acgccgatac gcggacgaag cgcgggaggg ggatcggccg tccctgtcct ttttcccacc
1321 caagcatcga ccggtccgcg ctagttccgc gtcgacggcg ggggtcgtcg gggtccgtgg
1381 gtctcgcccc ctccccccat cgagagtccg taggtgacct accgtgctac gtccgccgtc
1441 gcagccgtat ccccggagga tcgccccgca tcggcgatgg cgtcggagaa caagcagcgc
1501 cccggctccc cgggccccac cgacgggccg ccgcccaccc cgagcccaga ccgcgacgag
1561 cggggggccc tcgggtgggg cgcggagacg gaggagggcg gggacgaccc cgaccacgac
1621 cccgaccacc cccacgacct cgacgacgcc cggcgggacg ggagggcccc cgcggcgggc
1681 accgacgccg gcgaggacgc cggggacgcc gtctcgccgc gacagctggc tctgctggcc
1741 tccatggtag aggaggccgt ccggacgatc ccgacgcccg accccgcggc ctcgccgccc
1801 cggacccccg cctttcgagc cgacgacgat gacggggacg agtacgacga cgcagccgac
1861 gccgccggcg accgggcccc ggcccggggc cgcgaacggg aggccccgct acgcggcgcg
1921 tatccggacc ccacggaccg cctgtcgccg cgcccgccgg cccagccgcc gcggagacgt
1981 cgtcacggcc ggtggcggcc atcggcgtca tcgacctcgt cggactccgg gtcctcgtcc
2041 tcgtcgtccg catcctcttc gtcctcgtcg tccgacgagg acgaggacga cgacggcaac
2101 gacgcggccg accacgcacg cgaggcgcgg gccgtcgggc ggggtccgtc gagcgcggcg
2161 ccggcagccc ccgggcggac gccgcccccg cccgggccac cccccctctc cgaggccgcg
2221 cccaagcccc gggcggcggc gaggaccccc gcggcctccg cgggccgcat cgagcgccgc
2281 cgggcccgcg cggcggtggc cggccgcgac gccacgggcc gcttcacggc cgggcagccc
2341 cggcgggtcg agctggacgc cgacgcgacc tccggcgcct tctacgcgcg ctatcgcgac
2401 gggtacgtca gcggggagcc gtggcccggc gccgggcccc cgcccccggg gcgggtgctg
2461 tacggcggcc tgggcgacag ccgcccgggc ctctgggggg cgcccgaggc ggaggaggcg
2521 cgacgccggt tcgaggcctc gggcgccccg gcggccgtgt gggcgcccga gctgggcgac
2581 gccgcgcagc agtacgccct gatcacgcgg ctgctgtaca ccccggacgc ggaggccatg
2641 gggtggctcc agaacccgcg cgtggtcccc ggggacgtgg cgctggacca ggcctgcttc
2701 cggatctcgg gcgccgcgcg caacagcagc tccttcatca ccggcagcgt ggcgcgggcc
2761 gtgccccacc tgggctacgc catggcggcc ggccgcttcg gctggggcct ggcgcacgcg
2821 gcggccgccg tggccatgag ccgccgatac gaccgcgcgc agaagggctt cctgctgacc
2881 agcctgcgcc gcgcctacgc gcccctgttg gcgcgcgaga acgcggcgct gacgggggcc
2941 gcggggagcc ccggcgccgg cgcagatgac gagggggtcg ccgccgtcgc cgccgccgca
3001 ccgggcgagc gcgcggtgcc cgccgggtac ggcgccgcgg ggatcctcgc cgccctgggg
3061 cggctgtccg ccgcgcccgc ctcccccgcg gggggcgacg accccgacgc cgcccgccac
3121 gccgacgccg acgacgacgc cgggcgccgc gcccaggccg gccgcgtggc cgtcgagtgc
3181 ctggccgcct gccgcgggat cctggaggcg ctggccgagg gcttcgacgg cgacctggcg
3241 gccgtcccgg ggctggccgg ggcccggccc gccagccccc cgcggccgga gggacccgcg
3301 ggccccgctt ccccgccgcc gccgcacgcc gacgcgcccc gcctgcgcgc gtggctgcgc
3361 gagctgcggt tcgtgcgcga cgcgctggtg ctcatgcgcc tgcgcgggga cctgcgcgtg
3421 gccggcggca gcgaggccgc cgtggccgcc gtgcgcgccg tgagcctggt cgccggggcc
3481 ctgggccccg cgctgccgcg ggacccgcgc ctgccgagct ccgcggccgc cgccgccgcg
3541 gacctgctgt ttgacaacca gagcctgcgc cccctgctgg cggcggcggc cagcgcaccg
3601 gacgccgccg acgcgctggc ggccgccgcc gcctccgccg cgccgcggga ggggcgcaag
3661 cgcaagagtc ccggcccggc ccggccgccc ggaggcggcg gcccgcgacc cccgaagacg
3721 aagaagagcg gcgcggacgc ccccggctcg gacgcccgcg cccccctccc cgcgcccgcg
3781 cccccctcca cgcccccggg gcccgagccc gcccccgccc agcccgcggc gccccgggcc
3841 gccgcggcgc aggcccgccc gcgccccgtg gccgtgtcgc gccggcccgc cgagggcccc
3901 gaccccctgg gcggctggcg gcggcagccc ccggggccca gccacacggc ggcgcccgcg
3961 gccgccgccc tggaggccta ctgctccccg cgcgccgtgg ccgagctcac ggaccacccg
4021 ctgttccccg tcccctggcg accggccctc atgtttgacc cgcgggccct ggcctcgatc
4081 gccgcgcggt gcgccgggcc cgcccccgcc gcccaggccg cgtgcggcgg cggcgacgac
4141 gacgataacc cccaccccca cggggccgcc gggggccgcc tctttggccc cctgcgcgcc
4201 tcgggcccgc tgcgccgcat ggcggcctgg atgcgccaga tccccgaccc cgaggacgtg
4261 cgcgtggtgg tgctgtactc gccgctgccg ggcgaggacc tggccggcgg cggggcctcg
4321 ggggggccgc cggagtggtc cgccgagcgc ggcgggctgt cctgcctgct ggcggccctg
4381 gccaaccggc tgtgcgggcc ggacacggcc gcctgggcgg gcaattggac cggcgccccc
4441 gacgtgtcgg cgctgggcgc acagggcgtg ctgctgctgt ccacgcggga cctggccttc
4501 gccggggccg tggagtttct ggggctgctc gccagcgccg gcgaccggcg gctcatcgtg
4561 gtcaacaccg tgcgcgcctg cgactggccc gccgacgggc ccgcggtgtc gcggcagcac
4621 gcctacctgg cgtgcgagct gctgcccgcc gtgcagtgcg ccgtgcgctg gccggcggcg
4681 cgggacctgc gccgcacggt gctggcctcg ggccgcgtgt tcggcccggg ggtcttcgcg
4741 cgcgtggagg ccgcgcacgc gcgcctgtac cccgacgcgc cgccgctgcg cctgtgccgc
4801 ggcggcaacg tgcgctaccg cgtgcgcacg cgcttcggcc cggacacgcc ggtgcccatg
4861 tccccgcgcg agtaccgccg ggccgtgctg ccggcgctgg acggccgggc ggcggcctcg
4921 gggaccaccg acgccatggc gcccggcgcg ccggacttct gcgaggagga ggcccactcg
4981 cacgccgcct gcgcgcgctg gggcctgggc gcgccgctgc ggcccgtgta cgtggcgctg
5041 gggcgcgagg cggtgcgcgc cggcccggcc cggtggcgcg ggccgcggag ggacttttgc
5101 gcccgcgccc tgctggagcc cgacgacgac gcccccccgc tggtgctgcg cggcgacgac
5161 gacggcccgg gggccctgcc gccggcgccg cccgggattc gctgggcctc ggccacgggc
5221 cgcagcggca ccgtgctggc ggcggcgggg gccgtggagg tgctgggggc ggaggcgggc
5281 ttggccacgc ccccgcggcg ggaagttgtg gactgggaag gcgcctggga cgaagacgac
5341 ggcggcgcgt tcgaggggga cggggtgctg taacgggccg ggacggggcg gggcgcttgt
5401 gagacccgaa gacgcaataa acggcaacaa cctgattaag ttttgcagta gcgttgttta
5461 ttcgaggggc gggagggggc gaggggcggg agggggcgag gggcgggagg gggcgagggg
5521 cgggaggggg cgaggggcgg gagggggcga ggggcgggag ggggcgaggg gcgggagggg
5581 gcgaggggcg ggagggggcg aggggcggga gggggcgagg ggcgggaggg ggcgaggggc
5641 gggagggggc gaggggcggg agggggcgag gggcgggagg gggcgagggg cgggaggggg
5701 cgaggggcgg gagggggcga ggggcgggag ggggcgaggg gcgggagggg gcgaggggcg
5761 ggagggggcg aggggcggga gggggcgagg ggcggtggtg gtgcgcgggc gcccccggag
5821 ggtttggatc tctgacctga gattggcggc actgaggtag agatgcccga acccccccga
5881 gggagcgcgg gacgcgccgg ggagggctgg ggccggggag ggctggggcc ggggagggct
5941 ggggccgggg agggctgggg ccggggaggg ctggggccgg ggagggctgg ggccggggag
6001 ggctggggct ggggagggct ggggctgggg agggggcggt ggtgtgtagc aggagcggtg
6061 tgttgcgccg gggtacgtct ggaggagcgg gaggtgcgcg gtgacgtgtg gatgaggaac
6121 aggagttgtt gcgcggtgag ttgtcgctgt gagttgtgtt gttgggcagg tgtggtggat
6181 gacgtgacgt gtgacgtgcg gagtgcgccg tgctctgttg gtttcacctg tggcagcccg
6241 ggccccccgc gggcgcgcgc gcgcgcaaaa aaggcgggcg gcggtccggg cggcgtgcgc
6301 gcgcgcggcg ggcgtggggg gcggggccgc gggagcgggg ggaggagcgg ggggaggagc
6361 ggggggagga gcggggggag gagcgggggg aggagcgggg ggaggagcgg ggggaggagc
6421 ggggggagga gcggggggag gagcgggggg aggagcgggg ggaggagcgg ggggaggagc
6481 ggggggagga gcggggggag gagcgggggg aggagcgggg ggaggagcgg ggggaggagc
6541 ggggggagga gcggccagac gccgaaaacg ggcccccccc aaaacacacc ccccgggggt
6601 cgcgcgcggc cctttaaagc ggtggcggcg ggc
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