GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS HIVV2RODX 9671 bp ss-mRNA VRL 28-MAY-1991
DEFINITION Human immunodeficiency virus type 2 ROD isolate RNA genome (HIV-2)
ACCESSION X05291
KEYWORDS acquired immune deficiency syndrome; art gene; env gene; f gene;
gag gene; pol gene; q gene; r gene; tat gene.
SOURCE Human immunodeficiency virus type 2 RNA.
ORGANISM Human immunodeficiency virus type 2
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Lentivirinae.
REFERENCE 1 (sites)
AUTHORS Clavel,F., Guyader,M., Guetard,D., Salle,M., Montagnier,L. and
Alizon,M.
TITLE Molecular cloning and polymorphism of the human immunodeficiency
virus type 2
JOURNAL Nature 324, 691-695 (1986)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 9671)
AUTHORS Alison,M.
JOURNAL Unpublished (1987)
STANDARD full automatic
REFERENCE 3 (bases 1 to 9671)
AUTHORS Guyader,M., Emerman,M., Sonigo,P., Clavel,F., Montagnier,L. and
Alizon,M.
TITLE Genome organization and transactivation of the human immuno-
deficiency virus type 2
JOURNAL Nature 326, 662-669 (1987)
STANDARD full automatic
COMMENT EPD; 16081; HIV-2(ROD). SWISS-PROT; P04577; ENV$HIV2R. SWISS-PROT;
P04584; POL$HIV2R. SWISS-PROT; P04590; GAG$HIV2R. SWISS-PROT;
P04595; VIF$HIV2R. SWISS-PROT; P04600; NEF$HIV2R. SWISS-PROT;
P04605; TAT$HIV2R. SWISS-PROT; P04615; REV$HIV2R. SWISS-PROT;
P06938; VPR$HIV2R. SWISS-PROT; P06939; VPX$HIV2R.
From EMBL entry HIV2RODX; dated 18-DEC-1990.
FEATURES Location/Qualifiers
CDS join(5845..6140,8307..8400)
/product="tat protein"
/codon_start=5845
CDS join(6071..6140,8307..8536)
/product="art protein"
/codon_start=6071
misc_feature 1..9671
/note="HIV-2 RNA corresponding to integrated proviral DNA"
repeat_region 1..299
/note="LTR"
misc_feature 1..173
/note="R region"
misc_feature 174..299
/note="U5 region"
misc_feature 303..320
/note="primer binding site"
CDS 546..2111
/product="gag protein"
/codon_start=546
CDS 1829..4936
/product="pol protein"
/codon_start=1829
misc_feature 4613..4626
/note="polypurine tract 2"
CDS 4869..5513
/product="q protein"
/codon_start=4869
CDS 5682..5996
/product="r protein"
/codon_start=5682
CDS 6147..8720
/product="env protein"
/codon_start=6147
CDS 8557..9324
/product="f protein"
/codon_start=8557
misc_feature 8925..8939
/note="polypurine tract 1"
repeat_region 8942..9671
/note="LTR"
misc_feature 8942..9497
/note="U3 region"
promoter 9329..9339
/note="core enhancer sequence"
promoter 9401..9416
/note="core enhancer sequence"
misc_feature 9420..9427
/note="pot. SP1 factor binding site"
misc_feature 9428..9437
/note="pot. SP1 factor binding site"
misc_feature 9438..9448
/note="pot. SP1 factor binding site"
promoter 9465..9470
/note="TATA-box"
misc_feature 9498..9671
/note="R region"
misc_feature 9649..9654
/note="pot. polyA signal"
polyA_site 9671..9671
/note="polyA site"
BASE COUNT 3314 a 1973 c 2401 g 1983 t
ORIGIN
1 ggtcgctctg cggagaggct ggcagattga gccctgggag gttctctcca gcactagcag
61 gtagagcctg ggtgttccct gctagactct caccagcact tggccggtgc tgggcagacg
121 gccccacgct tgcttgctta aaaacctctt aataaagctg ccagttagaa gcaagttaag
181 tgtgtgctcc catctctcct agtcgccgcc tggtcattcg gtgttcacct gagtaacaag
241 accctggtct gttaggaccc ttcttgcttt gggaaaccga ggcaggaaaa tccctagcag
301 gttggcgcct gaacagggac ttgaagaaga ctgagaagtc ttggaacacg gctgagtgaa
361 ggcagtaagg gcggcaggaa caaaccacga cggagtgctc ctagaaaggc gcgggccgag
421 gtaccaaagg cagcgtgtgg agcgggagga gaagaggcct ccgggtgaag gtaagtacct
481 acaccaaaaa ctgtagccga aagggcttgc tatcctacct ttagacaggt agaagattgt
541 gggagatggg cgcgagaaac tccgtcttga gagggaaaaa agcagatgaa ttagaaagaa
601 tcaggttacg gcccggcgga aagaaaaagt acaggctaaa acatattgtg tgggcagcga
661 ataaattgga cagattcgga ttagcagaga gcctgttgga gtcaaaagag ggttgtcaaa
721 aaattcttac agttttagat ccaatggtac cgacaggttc agaaaattta aaaagtcttt
781 ttaatactgt ctgcgtcatt tggtgcatac acgcagaaga gaaagtgaaa gatactgaag
841 gagcaaaaca aatagtgcgg agacatctag tggcagaaac aggaactgca gagaaaatgc
901 caagcacaag tagaccaaca gcaccatcta gcgagaaggg aggaaattac ccagtgcaac
961 atgtaggcgg caactacacc catataccgc tgagtccccg aaccctaaat gcctgggtaa
1021 aattagtaga ggaaaaaaag ttcggggcag aagtagtgcc aggatttcag gcactctcag
1081 aaggctgcac gccctatgat atcaaccaaa tgcttaattg tgtgggcgac catcaagcag
1141 ccatgcagat aatcagggag attatcaatg aggaagcagc agaatgggat gtgcaacatc
1201 caataccagg ccccttacca gcggggcagc ttagagagcc aaggggatct gacatagcag
1261 ggacaacaag cacagtagaa gaacagatcc agtggatgtt taggccacaa aatcctgtac
1321 cagtaggaaa catctataga agatggatcc agataggatt gcagaagtgt gtcaggatgt
1381 acaacccgac caacatccta gacataaaac agggaccaaa ggagccgttc caaagctatg
1441 tagatagatt ctacaaaagc ttgagggcag aacaaacaga tccagcagtg aagaattgga
1501 tgacccaaac actgctagta caaaatgcca acccagactg taaattagtg ctaaaaggac
1561 tagggatgaa ccctacctta gaagagatgc tgaccgcctg tcagggggta ggtgggccag
1621 gccagaaagc tagattaatg gcagaggccc tgaaagaggt cataggacct gcccctatcc
1681 cattcgcagc agcccagcag agaaaggcat ttaaatgctg gaactgtgga aaggaagggc
1741 actcggcaag acaatgccga gcacctagaa ggcagggctg ctggaagtgt ggtaagccag
1801 gacacatcat gacaaactgc ccagatagac aggcaggttt tttaggactg ggcccttggg
1861 gaaagaagcc ccgcaacttc cccgtggccc aagttccgca ggggctgaca ccaacagcac
1921 ccccagtgga tccagcagtg gatctactgg agaaatatat gcagcaaggg aaaagacaga
1981 gagagcagag agagagacca tacaaggaag tgacagagga cttactgcac ctcgagcagg
2041 gggagacacc atacagggag ccaccaacag aggacttgct gcacctcaat tctctctttg
2101 gaaaagacca gtagtcacag catacattga gggtcagcca gtagaagtct tgttagacac
2161 aggggctgac gactcaatag tagcaggaat agagttaggg aacaattata gcccaaaaat
2221 agtaggggga atagggggat tcataaatac caaggaatat aaaaatgtag aaatagaagt
2281 tctaaataaa aaggtacggg ccaccataat gacaggcgac accccaatca acatttttgg
2341 cagaaatatt ctgacagcct taggcatgtc attaaatcta ccagtcgcca aagtagagcc
2401 aataaaaata atgctaaagc cagggaaaga tggaccaaaa ctgagacaat ggcccttaac
2461 aaaagaaaaa atagaagcac taaaagaaat ctgtgaaaaa atggaaaaag aaggccagct
2521 agaggaagca cctccaacta atccttataa tacccccaca tttgcaatca agaaaaagga
2581 caaaaacaaa tggaggatgc taatagattt cagagaacta aacaaggtaa ctcaagattt
2641 cacagaaatt cagttaggaa ttccacaccc agcagggttg gccaagaaga gaagaattac
2701 tgtactagat gtaggggatg cttacttttc cataccacta catgaggact ttagaccata
2761 tactgcattt actctaccat cagtgaacaa tgcagaacca ggaaaaagat acatatataa
2821 agtcttgcca cagggatgga agggatcacc agcaattttt caacacacaa tgagacaggt
2881 attagaacca ttcagaaaag caaacaagga tgtcattatc attcagtaca tggatgatat
2941 cttaatagct agtgacagga cagatttaga acatgatagg gtagtcctgc agctcaagga
3001 acttctaaat ggcctaggat tttctacccc agatgagaag ttccaaaaag accctccata
3061 ccactggatg ggctatgaac tatggccaac taaatggaag ttgcagaaaa tacagttgcc
3121 ccaaaaagaa atatggacag tcaatgacat ccagaagcta gtgggtgtcc taaattgggc
3181 agcacaactc tacccaggga taaagaccaa acacttatgt aggttaatca gaggaaaaat
3241 gacactcaca gaagaagtac agtggacaga attagcagaa gcagagctag aagaaaacag
3301 aattatccta agccaggaac aagagggaca ctattaccaa gaagaaaaag agctagaagc
3361 aacagtccaa aaggatcaag agaatcagtg gacatataaa atacaccagg aagaaaaaat
3421 tctaaaagta ggaaaatatg caaaggtgaa aaacacccat accaatggaa tcagattgtt
3481 agcacaggta gttcagaaaa taggaaaaga agcactagtc atttggggac gaataccaaa
3541 atttcaccta ccagtagaga gagaaatctg ggagcagtgg tgggataact actggcaagt
3601 gacatggatc ccagactggg acttcgtgtc taccccacca ctggtcaggt tagcgtttaa
3661 cctggtaggg gatcctatac caggtgcaga gaccttctac acagatggat cctgcaatag
3721 gcaatcaaaa gaaggaaaag caggatatgt aacagataga gggaaagaca aggtaaagaa
3781 actagagcaa actaccaatc agcaagcaga actagaagcc tttgcgatgg cactaacaga
3841 ctcgggtcca aaagttaata ttatagtaga ctcacagtat gtaatgggga tcagtgcaag
3901 ccaaccaaca gagtcagaaa gtaaaatagt gaaccagatc atagaagaaa tgataaaaaa
3961 ggaagcaatc tatgttgcat gggtcccagc ccacaaaggc atagggggaa accaggaagt
4021 agatcattta gtgagtcagg gtatcagaca agtgttgttc ctggaaaaaa tagagcccgc
4081 tcaggaagaa catgaaaaat atcatagcaa tgtaaaagaa ctgtctcata aatttggaat
4141 acccaattta gtggcaaggc aaatagtaaa ctcatgtgcc caatgtcaac agaaagggga
4201 agctatacat gggcaagtaa atgcagaact aggcacttgg caaatggact gcacacattt
4261 agaaggaaag atcattatag tagcagtaca tgttgcaagt ggatttatag aagcagaagt
4321 catcccacag gaatcaggaa gacaaacagc actcttccta ttgaaactgg caagtaggtg
4381 gccaataaca cacttgcata cagataatgg tgccaacttc acttcacagg aggtgaagat
4441 ggtagcatgg tggataggta tagaacaatc ctttggagta ccttacaatc cacagagcca
4501 aggagtagta gaagcaatga atcaccatct aaaaaaccaa ataagtagaa tcagagaaca
4561 ggcaaataca atagaaacaa tagtactaat ggcaattcat tgcatgaatt ttaaaagaag
4621 ggggggaata ggggatatga ctccatcaga aagattaatc aatatgatca ccacagaaca
4681 agagatacaa ttcctccaag ccaaaaattc aaaattaaaa gattttcggg tctatttcag
4741 agaaggcaga gatcagttgt ggaaaggacc tggggaacta ctgtggaaag gagaaggagc
4801 agtcctagtc aaggtaggaa cagacataaa aataatacca agaaggaaag ccaagatcat
4861 cagagactat ggaggaagac aagagatgga tagtggttcc cacctggagg gtgccaggga
4921 ggatggagaa atggcatagc cttgtcaagt atctaaaata caaaacaaag gatctagaaa
4981 aggtgtgcta tgttccccac cataaggtgg gatgggcatg gtggacttgc agcagggtaa
5041 tattcccatt aaaaggaaac agtcatctag agatacaggc atattggaac ttaacaccag
5101 aaaaaggatg gctctcctct tattcagtaa gaataacttg gtacacagaa aagttctgga
5161 cagatgttac cccagactgt gcagatgtcc taatacatag cacttatttc ccttgcttta
5221 cagcaggtga agtaagaaga gccatcagag gggaaaagtt attgtcctgc tgcaattatc
5281 cccgagctca tagagcccag gtaccgtcac ttcaatttct ggccttagtg gtagtgcaac
5341 aaaatgacag accccagaga gacagtacca ccaggaaaca gcggcgaaga gactatcgga
5401 gaggccttcg cctggctaaa caggacagta gaagccataa acagagaagc agtgaatcac
5461 ctaccccgag aacttatttt ccaggtgtgg cagaggtcct ggagatactg gcatgatgaa
5521 caagggatgt cagaaagtta cacaaagtat agatatttgt gcataataca gaaagcagtg
5581 tacatgcatg ttaggaaagg gtgtacttgc ctggggaggg gacatgggcc aggagggtgg
5641 agaccagggc ctcctcctcc tccccctcca ggtctggtct aatggctgaa gcaccaacag
5701 agctcccccc ggtggatggg accccactga gggagccagg ggatgagtgg ataatagaaa
5761 tcttgagaga aataaaagaa gaagctttaa agcattttga ccctcgcttg ctaattgctc
5821 ttggcaaata tatctatact agacatggag acacccttga aggcgccaga gagctcatta
5881 aagtcctgca acgagccctt ttcacgcact tcagagcagg atgtggccac tcaagaattg
5941 gccagacaag gggaggaaat cctctctcag ctataccgac ccctagaaac atgcaataac
6001 tcatgctatt gtaagcgatg ctgctaccat tgtcagatgt gttttctaaa caaggggctc
6061 gggatatgtt atgaacgaaa gggcagacga agaaggactc caaagaaaac taagactcat
6121 ccgtctccta caccagacaa gtgagtatga tgaatcagct gcttattgcc attttattag
6181 ctagtgcttg cttagtatat tgcacccaat atgtaactgt tttctatggc gtacccacgt
6241 ggaaaaatgc aaccattccc ctcttttgtg caaccagaaa tagggatact tggggaacca
6301 tacagtgctt gcctgacaat gatgattatc aggaaataac tttgaatgta acagaggctt
6361 ttgatgcatg gaataataca gtaacagaac aagcaataga agatgtctgg catctattcg
6421 agacatcaat aaaaccatgt gtcaaactaa cacctttatg tgtagcaatg aaatgcagca
6481 gcacagagag cagcacaggg aacaacacaa cctcaaagag cacaagcaca accacaacca
6541 cacccacaga ccaggagcaa gagataagtg aggatactcc atgcgcacgc gcagacaact
6601 gctcaggatt gggagaggaa gaaacgatca attgccagtt caatatgaca ggattagaaa
6661 gagataagaa aaaacagtat aatgaaacat ggtactcaaa agatgtggtt tgtgagacaa
6721 ataatagcac aaatcagacc cagtgttaca tgaaccattg caacacatca gtcatcacag
6781 aatcatgtga caagcactat tgggatgcta taaggtttag atactgtgca ccaccgggtt
6841 atgccctatt aagatgtaat gataccaatt attcaggctt tgcacccaac tgttctaaag
6901 tagtagcttc tacatgcacc aggatgatgg aaacgcaaac ttccacatgg tttggcttta
6961 atggcactag agcagagaat agaacatata tctattggca tggcagagat aatagaacta
7021 tcatcagctt aaacaaatat tataatctca gtttgcattg taagaggcca gggaataaga
7081 cagtgaaaca aataatgctt atgtcaggac atgtgtttca ctcccactac cagccgatca
7141 ataaaagacc cagacaagca tggtgctggt tcaaaggcaa atggaaagac gccatgcagg
7201 aggtgaagga aacccttgca aaacatccca ggtatagagg aaccaatgac acaaggaata
7261 ttagctttgc agcgccagga aaaggctcag acccagaagt agcatacatg tggactaact
7321 gcagaggaga gtttctctac tgcaacatga cttggttcct caattggata gagaataaga
7381 cacaccgcaa ttatgcaccg tgccatataa agcaaataat taacacatgg cataaggtag
7441 ggagaaatgt atatttgcct cccagggaag gggagctgtc ctgcaactca acagtaacca
7501 gcataattgc taacattgac tggcaaaaca ataatcagac aaacattacc tttagtgcag
7561 aggtggcaga actatacaga ttggagttgg gagattataa attggtagaa ataacaccaa
7621 ttggcttcgc acctacaaaa gaaaaaagat actcctctgc tcacgggaga catacaagag
7681 gtgtgttcgt gctagggttc ttgggttttc tcgcaacagc aggttctgca atgggcgcgg
7741 cgtccctgac cgtgtcggct cagtcccgga ctttactggc cgggatagtg cagcaacagc
7801 aacagctgtt ggacgtggtc aagagacaac aagaactgtt gcgactgacc gtctggggaa
7861 cgaaaaacct ccaggcaaga gtcactgcta tagagaagta cctacaggac caggcgcggc
7921 taaattcatg gggatgtgcg tttagacaag tctgccacac tactgtacca tgggttaatg
7981 attccttagc acctgactgg gacaatatga cgtggcagga atgggaaaaa caagtccgct
8041 acctggaggc aaatatcagt aaaagtttag aacaggcaca aattcagcaa gagaaaaata
8101 tgtatgaact acaaaaatta aatagctggg atatttttgg caattggttt gacttaacct
8161 cctgggtcaa gtatattcaa tatggagtgc ttataatagt agcagtaata gctttaagaa
8221 tagtgatata tgtagtacaa atgttaagta ggcttagaaa gggctatagg cctgttttct
8281 cttccccccc cggttatatc caacagatcc atatccacaa ggaccgggga cagccagcca
8341 acgaagaaac agaagaagac ggtggaagca acggtggaga cagatactgg ccctggccga
8401 tagcatatat acatttcctg atccgccagc tgattcgcct cttgaccaga ctatacagca
8461 tctgcaggga cttactatcc aggagcttcc tgaccctcca actcatctac cagaatctca
8521 gagactggct gagacttaga acagccttct tgcaatatgg gtgcgagtgg atccaagaag
8581 cattccaggc cgccgcgagg gctacaagag agactcttgc gggcgcgtgc aggggcttgt
8641 ggagggtatt ggaacgaatc gggaggggaa tactcgcggt tccaagaagg atcagacagg
8701 gagcagaaat cgccctcctg tgagggacgg cagtatcagc agggagactt tatgaatact
8761 ccatggaagg acccagcagc agaaagggag aaaaatttgt acaggcaaca aaatatggat
8821 gatgtagatt cagatgatga tgaccaagta agagtttctg tcacaccaaa agtaccacta
8881 agaccaatga cacatagatt ggcaatagat atgtcacatt taataaaaac aaggggggga
8941 ctggaaggga tgttttacag tgaaagaaga cataaaatct taaatatata cttagaaaag
9001 gaagaaggga taattgcaga ttggcagaac tacactcatg ggccaggagt aagataccca
9061 atgttctttg ggtggctatg gaagctagta ccagtagatg tcccacaaga aggggaggac
9121 actgagactc actgcttagt acatccagca caaacaagca agtttgatga cccgcatggg
9181 gagacactag tctgggagtt tgatcccttg ctggcttata gttacgaggc ttttattcgg
9241 tacccagagg aatttgggca caagtcaggc ctgccagagg aagagtggaa ggcgagactg
9301 aaagcaagag gaataccatt tagttaaaga caggaacagc tatacttggt cagggcagga
9361 agtaactaac agaaacagct gagactgcag ggactttcca gaaggggctg taaccaaggg
9421 agggacatgg gaggagctgg tggggaacgc cctcatattc tctgtataaa tatacccgct
9481 agcttgcatt gtacttcggt cgctctgcgg agaggctggc agattgagcc ctgggaggtt
9541 ctctccagca gtagcaggta gagcctgggt gttccctgct agactctcac cagcacttgg
9601 ccggtgctgg gcagacggcc ccacgcttgc ttgcttaaaa acctccttaa taaagctgcc
9661 agttagaagc a
//