GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS FLBFLBL40 2381 bp ss-mRNA VRL 28-MAY-1991
DEFINITION Influenza B/lee/40 virus, polymerase PB1, complete genome.
ACCESSION D00004 N00004
KEYWORDS PB1 protein; RNA polymerase; complete genome; polymerase.
SOURCE Influenza virus type B RNA.
ORGANISM Influenza virus type B
Viridae; ss-RNA enveloped viruses; Negative strand RNA viruses;
Orthomyxoviridae; Influenzavirus.
REFERENCE 1 (bases 1 to 2381)
AUTHORS Kemdirim,S., Palefsky,J. and Briedis,D.J.
TITLE Influenza B virus PB1 protein: Nucleotide sequence of the genome
RNA segment predicts a high degree of structural homology with the
corresponding influenza A virus polymerase protein
JOURNAL Virology 152, 126-135 (1986)
STANDARD full automatic
COMMENT PB1 genome RNA segment is 2368 nucleotides. Sequence comparison
between the influenza A and B virus PB1 proteins reveals that they
share the highest homology (61% amino acid homology, reported in
[1]) yet seen between proteins encoded by these disparate viruses.
In [1], first non-viral 13 nucleotides are presumably derived from
the 5' end of an influenza mRNA to which they had been transferred
from a cellular mRNA during the transcription initiation process of
virus mRNA synthesis.
From EMBL entry ORFLBL40; dated 17-JAN-1991.
FEATURES Location/Qualifiers
precursor_RNA <1..13
/note="non-viral HeLa mRNA"
precursor_RNA complement(14..2381)
/note="polymerase PB1 complete genome"
CDS 34..2292
/note="PB1 peptide (497th a may be t to code leu.)"
/codon_start=34
BASE COUNT 868 a 406 c 529 g 578 t
ORIGIN
1 aggatctagc agcagcagaa gcggagcttt aagatgaata taaatccata ttttcttttc
61 atagatgtac ctatacaggc agcaatttca acaacattcc catacaccgg tgttccccct
121 tattctcatg gaacgggaac aggctacaca atagacaccg tgattagaac acacgagtac
181 tcaaacaagg gaaaacaata catttctgat gttacaggat gtgtaatggt agatccaaca
241 aatgggccat tacccgaaga caatgaaccg agtgcctatg cacaattgga ttgtgttctg
301 gaggctttgg atagaatgga tgaagaacat ccaggtctgt ttcaagcagg gtcacagaat
361 gccatggagg cactaatggt cacaacagtg gacaaattga ctcaggggag acagaccttt
421 gattggacgg tgtgtagaaa ccaacctgct gcaacggcac tgaacacaac aataacctct
481 tttaggttga atgattaaaa tggagccgac aagggtggat tagtgccctt ttgccaagat
541 atcattgatt cattagacaa acctgaaatg attttcttca cagtaaagaa tataaagaaa
601 aaattgcctg ctaaaaacag aaagggtttc cttataaaaa gaatacctat gaaggtaaaa
661 gacagaataa caagagtgga atacatcaaa agagcattat cattaaacac aatgactaaa
721 gatgctgaaa gaggcaaact aaaaagaaga gcaattgcca ccgctgggat acaaatcaga
781 ggatttgtat tagtagttga aaacttggct aaaaatatct gtgaaaatct agagcaaagt
841 ggtttacccg taggtggaaa cgaaaagaag gccaaactat caaatgcagt ggctaaaatg
901 ctcagtaatt gtccaccagg agggatcagt atgactgtga caggagacaa tactaaatgg
961 aatgaatgct taaatccaag aatctttttg gctatgactg aaagaataac cagagacagc
1021 ccaatttggt tccgggattt ttgtagtata gcaccggtct tgttctccaa taaaatagct
1081 agattgggaa aagggttcat gataacaagt aaaacaaaaa gcctaaaagc tcaaatacct
1141 tgtcccgatc tgtttaatat accattagaa agatataatg aagaaacaag ggcaaaactg
1201 aaaaagctaa aacctttctt caatgaagaa ggaacggcat ctctttcgcc aggaatgatg
1261 atgggaatgt ttaatatgct atctacagta ttaggagtag ccgcactagg gataaaaaac
1321 attggaaaca aagaatactt atgggatgga ctgcagtctt cggatgattt tgctctgttt
1381 gttaatgcaa aagatgaaga gacatgtatg gaaggaataa acgattttta ccgaacatgt
1441 aagctattgg gaataaacat gagcaaaaag aaaagttact gtaatgaaac tgggatgttt
1501 gaatttacca gcatgtttta cagagatgga tttgtatcta attttgcaat ggaactccct
1561 tcatttggag tcgctggagt gaatgaatca gcagacatgg caataggaat gacaataata
1621 aagaacaata tgatcaacaa tgggatgggc ccagcaacgg cacaaacagc catacaatta
1681 ttcatagctg actatagata cacctacaaa tgccacaggg gagattccaa agtggaaggg
1741 aagagaatga aaattataaa ggagctatgg gaaaacacta aaggaagaga tggtctatta
1801 gtagcagatg gtgggcctaa tctttacaat ttgagaaacc tgcatattcc agaaataata
1861 ttaaaataca acataatgga ccctgagtac aaaggacggt tactgcatcc tcaaaatccc
1921 tttgtaggac atttgtctat tgagggtatc aaagaagcag atataacacc tgcacatggc
1981 ccaataaaga aaatggacta cgatgcggta tctggaactc atagttggag aaccaaaagg
2041 aacagatcta tactaaacac tgatcagagg aacatgattc ttgaggaaca atgctacgct
2101 aagtgttgca acctttttga ggcttgcttt aacagtgcgt catacaggaa accagtaggc
2161 cagcacagca tgcttgaagc tatggcccac agattaagaa tggatgcacg actggactat
2221 gagtcaggaa ggatgtcaaa agaggatttc gaaaaagcaa tggctcacct tggtgagatt
2281 gggtacatgt aagctccgga aatgtctatg gggttattgg tcatcgttga atacatgcgg
2341 tgcacaaatg attaaaatga aaaaaggctc gtgtttctac t
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