GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS PVBBKVMM 4963 bp ds-DNA VRL 28-MAY-1991
DEFINITION Human BK virus (strain MM) genome. (Closely related to SV40.)
ACCESSION V01109
KEYWORDS circular; genome.
SOURCE Papovavirus BKV DNA.
ORGANISM Papovavirus BKV
Viridae; ds-DNA nonenveloped viruses; Papovaviridae;
Papillomavirus.
REFERENCE 1 (bases 1 to 4963)
AUTHORS Yang,R.C. and Wu,R.
TITLE BK Virus DNA: Complete Nucleotide Sequence of a Human Tumor Virus
JOURNAL Science 206, 456-462 (1979)
STANDARD full automatic
COMMENT SWISS-PROT; P03071; TALA$POVBK. SWISS-PROT; P03082; TASM$POVBK.
SWISS-PROT; P03085; DNBI$POVBK. SWISS-PROT; P03088; COA1$POVBK.
SWISS-PROT; P03094; COA2$POVBK.
This entry was previously named <PAPSMTZ1>.
The sequence is listed beginning at the second base of the unique
Eco RI site, which is used as map position 0 or 1.0 in the standard
physical map. The polarity is that of the late mRNAs.
From EMBL entry PABKVMM; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS complement(884..2725)
/note="large T antigen (part 2)"
/codon_start=2725
intron complement(2726..2807)
/note="putative IVS for large T antigen"
CDS complement(2748..3047)
/note="small t antigen"
/codon_start=3047
CDS complement(2808..3047)
/note="large T antigen (part 1)"
/codon_start=3047
rep_origin 3144..3166
/note="origin of replication"
CDS 3510..3707
/note="putative VPx"
/codon_start=3510
CDS 3746..4798
/note="VP2"
/codon_start=3746
CDS 4103..4798
/note="VP3"
/codon_start=4103
CDS 4686..811
/note="VP1 (circular; across map position 0)"
/codon_start=4686
BASE COUNT 1478 a 996 c 989 g 1500 t
ORIGIN
1 aattcccctc cccaatttaa atgaggacct aacctgtgga aatctactga tgtgggaggc
61 tgtaactgta caaacagagg ttattggaat aactagcatg cttaaccttc atgcagggtc
121 acaaaaagtg catgagcatg gtggaggaaa acctattcaa ggcagtaatt tccacttctt
181 tgctgttggt ggagacccct tggaaatgca gggagtgcta atgaattaca ggacaaagta
241 cccagatggt actataaccc ctaaaaaccc aacagcccag tcccaggtaa tgaatactga
301 ccataaggcc tatttggaca aaaacaatgc ttatccagtt gagtgctggg ttcctgatcc
361 tagtagaaat gaaaatacta ggtattttgg gactttcaca ggaggggaaa atgttccccc
421 agtacttcat gtgaccaaca cagctaccac agtgttgcta gatgaacagg gtgtggggcc
481 tctttgtaaa gctgatagcc tgtatgtttc agctgctgat atttgtggcc tgtttactaa
541 cagctctgga acacaacagt ggagaggcct tgcaagatat tttaagatcc gcctgagaaa
601 aagatctgta aagaatcctt acctaatttc ctttttgcta agtgacctta taaacaggag
661 aacccagaga gtggatgggc agcctatgta tggtatggaa tcccaggtag aagaggttag
721 ggtgtttgat ggcacagaaa gacttccagg ggacccagat atgataagat atattgacaa
781 acagggacaa ttgcaaacca aaatgcttta aacaggtgct tttattgtac atatacattt
841 aataaatgct gcttttgtat aagccacttt taagcttgtg ttattttggg ggtggtgttt
901 taggcctttt aaaacactga aagcctttac acaaatgcaa ctcttgacta tgggggtctg
961 acctttggga atcttcagca ggggctgaag tatctgagac ttgggaagag cattgtgatt
1021 gggattcagt gcttgatcca tgtccagagt cttcagtttc tgaatcctct tctcttgtaa
1081 tatcaagaat acatttcccc atgcatatat tatatttcat ccttgaaaaa gtatacatac
1141 ttatctcaga atccagcctt tccttccatt caacaattct agattgtata tcagttgcaa
1201 aatcagctac aggcctaaac caaattagca gtagcaacaa ggtcattcca ctttgtaaaa
1261 ttcttttttc aagtaagaac tctgagtttt gtaaggattt tcttaaatat attttgggcc
1321 taaaatctat ttgtcttaca aatctagctt gcagggtttt agggacagga tactcattca
1381 ttgtaaccaa gcctggtgga aatatttggg ttcttttgtt taaatgtttc ttttctaaat
1441 ttaccttaac acttccatct aaataatctc tcaaactgtc taaattgttt attccatgtc
1501 ctgaaggcaa atcctttgat tcagctcctg tcccttttac atcttcaaaa acaaccatgt
1561 actgatctat agctacacct agctcaaagg ttagcctttc catgggtagg tttacattta
1621 aggctttacc tctacacaaa tctaacaacc ctgcagctag tgttgttttt ccactatcaa
1681 tgggaccttt aaataaccag tatcttcttt taggtacatt gaaaacaata cagtgcaaaa
1741 aatcaaatat tacagaatcc attttaggta gcaaacagtg cagccaagca acacctgcca
1801 tatattgttc tagtacagca tttccatgag ctccaaatat taaatccatt ttatctaata
1861 tatgattgaa tctttctgtt agcatttctt ccctggtcat atgaagggta tctactcttt
1921 ttttagctaa aactgtatct actgcttgct gacaaataac ttttttgttt ttactttctg
1981 caaaaataat agcatttgca aagtgctttt catgatactt aaagtgataa ggctggtctt
2041 ttttctgaca ctttttacac tcctctacat tgtattgaaa ttctaaatac atacctaata
2101 ataaaaacac atcctcacac tttgtctcta ctgcatactc agtaattaat ttccaagaca
2161 cctgctttgt ttcttcaggc tcttctgggt taaaatcatg ctcctttaag cccccttgaa
2221 tgctttcttc tatagtatgg tatggatctc tagttaaggc actatatagt aagtattcct
2281 tattaacacc cttacaaatt aaaaaactaa aggtacacag cttttgacag aaattattaa
2341 ttgcagaaac tctatgtcta tgtggagtta aaaagaatat aatattatgc ccagcacaca
2401 tgtgtctact aataaaagtt acagaatatt tttccataag ttttttatac agaatttgag
2461 ctttttcttt agtagtatac acagcaaagc aggcaagggt tctattacta aatacagctt
2521 gactaagaaa ctggtgtaga tcagagggaa agtctttagg gtcttctacc tttctttttt
2581 ttttgggtgg tgttgagtgt tgagaatctg ctgttgcttc ttcatcactg gcaaacatat
2641 cttcatggca aaataaatct tcatcccatt tttcattaaa ggaactccac caggactccc
2701 actcttctgt tccataggtt ggcacctata aaaaaaataa ttacttaggg cataggccat
2761 tccttgcagt acagggtatc tgggcaaaga ggaaaatcag cacaaacctc tgagctactc
2821 caggttccaa aatcaggctg atgagctacc tttacatcct gctccatttt tttatacaaa
2881 gtattcattc tcttcatttt atcctcgtcg ccccctttgt cagggtgaaa ttccttacac
2941 ttccttaaag cttttctcat taagggaaga tttccccagg cagctctttc aaggcctaaa
3001 aggtccatga gctccatgga ttcttccctg ttaagaactt tatccatttt tgcaaaaatt
3061 gcaaaagaat agggatttcc ccaaatagtt ttgctaggcc tcagaaaaag cctccacacc
3121 cttactactt gagagaaagg gtggaggcag aggcggcctc ggcctcttat atattataaa
3181 aaaaaaggcc acagggagga gctgcttacc catggaatgc agccaaacca tgacctcagg
3241 aaggaaagtg catgactggg cagccagcca gtggcagtta atagtgaaac cccgccccta
3301 aaatctctct tacccatgga atgcagccaa accatgacct caggaaggaa agtgcatgac
3361 tgggcagcca gccagtggca gttaatagtg aaaccatgcc aaaccatgac ctcaggaagg
3421 aaagtgcatg actgggcagc cagccagtgg cagttaattt gcgagcctag gaatcttggc
3481 cttgtcccca gttaaactgg acaaaggcca tggttctgcg ccagctgtca cgacaagctt
3541 cagtgaaagt tggtaaaacc tggactggaa caaaaaaaag agctcagagg atttttattt
3601 ttattttaga gcttttgctg gaattttgta gaggtgaaga cagtgtagac gggaaaaaca
3661 aaagtaccac tgctttacct gctgtaaaag actctgtaaa agactcctag gtaagtaatc
3721 cctttttttt tgtatttcca ggttcatggg tgctgctcta gcacttttgg gggacctagt
3781 tgccagtgta tctgaggctg ctgctgccac aggattttca gtggctgaaa ttgctgctgg
3841 ggaggctgct gctgctatag aagttcaaat tgcatccctt gctactgtag agggcataac
3901 aagtacctca gaggctatag ctgctatagg cctaactcct caaacatatg ctgtaattgc
3961 tggtgctcct ggggctattg ctgggtttgc tgctttaatt caaactgtta gtggtattag
4021 ttccttggct caagtagggt ataggttctt tagtgattgg gatcacaaag tttccactgt
4081 aggcctctat cagcaatcag gcatggcttt ggaattgttt aacccagatg agtactatga
4141 tattctgttt cctggtgtaa atacttttgt taataatatt caataccttg atcctaggca
4201 ttggggtcct tctttgtttg ctactatttc ccaggctttg tggcatgtta ttagggatga
4261 tataccttct ataacctcac aggaattgca gagaagaaca gaaagatttt ttagagactc
4321 cttggctaga tttttggagg aaactacctg gacaattgta aatgccccta taaactttta
4381 taattatatt caacaatatt attctgatct ttcccctatt aggccctcaa tggttagaca
4441 agtagctgaa agggaaggta cccgtgtaca ttttggccat acttatagta tagatgatgc
4501 tgacagtata gaagaagtta cacaaagaat ggacttaaga aatcaacaaa gtgtacattc
4561 aggagagttt atagaaaaaa ctattgcccc aggaggtgct aatcaaagaa ctgctcctca
4621 atggatgttg cctttacttc taggcctgta cgggactgta acacctgctc ttgaagcatg
4681 tgaagatggc cccaaccaaa agaaaaggag agtgtccagg ggcagctccc aaaaagccaa
4741 aggaacccgt gcaagtgcca aaactactaa taaaaggagg agtagaagtt ctagaagtta
4801 aaactggggt agatgctatt acagaggtag aatgcttcct aaacccagaa atgggggatc
4861 cagatgaaaa ccttaggggc tttagtctaa agctaagtgc tgaaaatgac tttagcagtg
4921 atagcccaga gagaaaaatg cttccctgtt acagcacagc aag
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