GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATCATHED 1934 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for preprocathepsin D (EC 3.4.23.5)
ACCESSION X54467
KEYWORDS aspartic protease; cathepsin; cathepsin D; lysosomal endoprotease.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1934)
AUTHORS Birch,N.P.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1934)
AUTHORS Birch,N.P. and Loh,Y.P.
TITLE Cloning, sequence and expression of rat cathepsin D
JOURNAL Nucleic Acids Res. 18, 6445-6446 (1990)
STANDARD full automatic
COMMENT *source: strain=Sprague Dawley; tissue=pituitary; *source: library=
Okayama Berg plasmid; clone=pCD-RAT; *source: developmental stage=
adult;
From EMBL entry RNCATHED; dated 15-JAN-1991.
FEATURES Location/Qualifiers
CDS 57..1277
/note="preprocathepsin D"
/codon_start=57
CDS 57..116
/note="signal peptide"
/codon_start=57
CDS 117..1277
/note="cathepsin D"
/codon_start=117
BASE COUNT 429 a 543 c 525 g 437 t
ORIGIN
1 cctataagcc ggcgacctct ggcattaagc tttgctctct tcgggccgtc gcgaccatgc
61 agacccccgg cgtcttgctg ctcattctcg gcctcctgga tgcgtcctcc tccgcgctta
121 tcagaatccc cctgcgcaag ttcacatcca tccgtcggac tatgacggaa gtgggaggct
181 ctgtggaaga cctgatcctt aaaggtccca taaccaagta ctccatgcag tcatctccta
241 ggaccaagga gccagtgtca gagttactaa aaaactacct ggatgcccag tactatggtg
301 agatcggcat tgggactccc ccacagtgtt tcacagtcgt ctttgacact ggctcctcta
361 acctgtgggt cccctccatt cattgcaagc tgctggacat agcctgctgg gtccaccaca
421 agtacaacag tgacaagtcc agcacctatg tgaagaatgg cacatccttc gacatccact
481 acggctcagg tagcctctct gggtacctga gccaggacac tgtgtcggtt ccatgtaagt
541 cagacttagg aggtatcaag gtggagaaac agatctttgg ggaagccacc aagcagcctg
601 gagtcgtatt catcgcagcc aagtttgatg gcatcttggg catgggctac ccttttatct
661 ctgttaacaa ggtgctcccg gtcttcgaca acctgatgaa acagaagctg gtggaaaaga
721 acatcttctc cttctacctg aacagggacc caaccgggca acctggagga gaactaatgc
781 ttggcggcac tgactccaga tactaccacg gggagctgtc ctacctgaac gtcacccgaa
841 aggcctactg gcaggtgcac atggaccagc tggaggtggg cagcgagctg accctgtgca
901 agggaggctg tgaggctatt gtggacacag ggacgtctct tctggtgggg cctgtggacg
961 aggtgaagga actacagaag gccattgggg cagtgcctct catccagggc gagtatatga
1021 tcccttgtga gaaggtgtcc agcctgccca ttatcacctt taagctagga ggccaaaact
1081 atgaactaca cccagagaag tacatactca aggtatcgca ggctggaaag acgatctgcc
1141 tgagtggctt catggggatg gacatacccc ctcccagtgg gccgctctgg atcctgggcg
1201 atgtctttat tggctgctac tacaccgtgt ttgacagaga atacaatagg gtcggctttg
1261 ccaaggctgc cacactctaa cttgctcctt cttcactgtc agggaactgg atcagagtcc
1321 agtagagaaa gccagccagc cccatccctc cacctgcccc actcacacat attcacactc
1381 gcctagtgtt gctgggccct tgggaggcct ggctggagct ggtccagctg ttctgttctg
1441 tggtccctgt ccctgggttc agattgctgc cctccgcctg tctgaaggag gccaaggcct
1501 acccagtaca aaaggctgcc tttaaaggcc cctactggct tggtagctgc cgggatgaat
1561 tgtcttgtcc tgctgccctt tgctgcgtgg gcagcactct gaagcaggca aatgggtctt
1621 gggatccctc ccagaaacct gctctgacca gaccctcagg cagcctgggg atggcaccaa
1681 gctctactgc cccactatct ctggcctggc aaaggctgaa ggtgagcaga aggagcaaga
1741 ggacagaagc aaaactatat gaacctgggg ggggttacct gggacctgac cccaccctcc
1801 tgggaaggca tgcttcagcc tggggcagag gtaggatggc tgactggttt tggctggcct
1861 ctgctgccct catcctgggc tagtcagatg ggagccaaag ttgatataca aataaagttg
1921 ttttgggcct cttt
//