GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATCHMCA 3275 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for cytosolic 3-hydroxy 3-methylglutaryl coenzyme A
synthase (EC 4.1.3.5)
ACCESSION X52625
KEYWORDS hydroxymethyl-CoA synthetase.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 3275)
AUTHORS Hegardt,F.G.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (sites)
AUTHORS Ayte,J., Gil-Gomez,G. and Hegardt,F.G.
TITLE Nucleotide sequence of a rat liver cDNA encoding the cytosolic
3-Hydroxy 3-methylglutaryl Coenzyme A synthase
JOURNAL Nucleic Acids Res. 18, 3642-3642 (1990)
STANDARD full staff_review
COMMENT SWISS-PROT; P17425; HMCS$RAT.
*source: strain=Sprague Dawley; clone=lambda-cCS1; tissue=liver;
From EMBL entry RNCHMCA; dated 18-OCT-1990.
FEATURES Location/Qualifiers
precursor_RNA 1..3275
/note="primary transcript"
old_sequence 31..70
/note="revised by [3]"
CDS 92..1651
/note="cytosolic 3-hydroxy 3-methylglutaryl coenzyme A
synthase (AA 1-520)"
/codon_start=92
BASE COUNT 934 a 634 c 789 g 918 t
ORIGIN
1 cccagggtcc gatcgcgttt ggtgcctgaa ggaggaaccg gtgacagacc tggagactac
61 agttctctgt ccttcacaca gctctttcac catgcctggg tcacttcctt tgaatgcaga
121 ggcttgctgg ccaaaagatg tgggaatcgt tgcccttgaa atctactttc cttctcagta
181 tgttgatcaa gctgagttgg aaaaatacga tggtgtagat gctggaaagt ataccattgg
241 cctgggccag gccaggatgg gcttctgcac ggatcgcgaa gacatcaact ctctctgcct
301 gactgtggtt cagaaactga tggagagaaa tagcctttcc tatgactgca ttgggcggct
361 ggaagtcggg acagagacaa tcatcgacaa atcaaaatcc gtgaagtcta atttgatgca
421 gctgtttgag gagtctggga atacagatat agaaggaata gatacaacta atgcatgcta
481 tgggggcaca gccgcagtct tcaatgctgt gaactggatc gaatccagct cttgggatgg
541 acgatacgct ttggtagttg caggagacat cgctatatat gcctcaggaa acgccaggcc
601 tacaggtgga gttggagctg tggctctgct aattgggcca aatgctcctg taatttttga
661 ccgagggctt cgtgggacac acatgcagca tgcctacgac ttttacaagc ctgacatgct
721 ctctgaatac cctgtggtag atggaaaact ctccatacag tgctacctca gcgcattgga
781 ccgctgctat tctgtctacc gcaaaaagat ccgggcccag tggcagaaag agggaaagga
841 taaagatttt accctgaatg attttggctt catgatcttt cactcgccat actgtaaact
901 ggtgcagaaa tctctagcta ggatgttcct gaatgacttt cttaacgatc aaaacagaga
961 caaaaacagt atttacagtg ggctggaagc ctttggggat gtgaaattag aagatactta
1021 cttcgacaga gatgtggaaa aggcatttat gaaggctagt gctgagctat tcaaccagaa
1081 aacaaaggca tctttgcttg tatcgaatca aaatggaaac atgtacacat cctctgtata
1141 cggttccctt gcttctgttc tggcacagta ctcacctcaa cagttggccg ggaagaggat
1201 tggagtgttc tcttacggtt ctggcttggc tgccacactc tactccctta aagtcacaca
1261 agatgccaca ccaggatctg ctcttgacaa aataacagca agtttatgtg accttaagtc
1321 aaggcttgac tcaagaacgt gtgtggcacc agacgtcttt gctgaaaaca tgaagctcag
1381 agaggacaca catcacttag ccaactatat tccccagtgt tcaatagatt cactcttcga
1441 aggaacatgg tatctagtca gagtggatga aaagcacaga agaacttacg cccggcgtcc
1501 ctccacaaat gaccacagtt tggatgaagg agtgggactt gtgcattcaa acacagctac
1561 agagcatatt ccaagcccgg ctaagaaagt gccaagactt cctgcgacct cgggcgaacc
1621 tgagtcggct gtcatcagta acggggagca ctgagagccg tggccttcac agaggctcgg
1681 ggctggatgg ggtatgggaa acgttagagg aatggatgtc ttgggacaat tttacagatt
1741 acgtgttgct taaaaatgta atgtaactga cacagagccc agaaaactgt tgtgtttttg
1801 gagaagtctc gctgagctcc taacacactt cctgctgtgg gctggccaat ggtgaatgta
1861 ctgcgatggt gttaagggct ctgcagaacg tcatacctcg ctgcatgttt acacgcatgc
1921 gggttaggct tcaaactcgg tctgaactga gtgcttctga ctgcaaaggc agaggtactg
1981 ctgtccagtt taaaaaattg tttttttttt ttttaatgtg taagaatttt tatacttaaa
2041 taaaaaaaag tacctgtagc ttttggggga aaaaaaaaaa cctttttcta ggttggggat
2101 tgtggaattt aaatgttaca cataaactct gcttaatggc aaggcaaaca tttatctttt
2161 tcgaagattt ataaatcctg aagagaaaaa aagagggtat ggttctagga tctggatgaa
2221 ccatcagtga gaaaggttag tcataatcaa gtgagcagaa ggatgctggc gttgagcagg
2281 cctctgtcac agcaaccagg gctctgtggg cacagctgag ggaactttct ggccaggtgc
2341 ccgtgactgc tgctcagctg cactgagatg cagtggagct gctgcacgga agcttgctgt
2401 ggtgctgaac gccttacctg cggataaagt gtaaagtagg agggatgggc agggcactat
2461 taggttacag tgttacagac ccaggttata gacttgacag ctcaaactca ccagacacct
2521 ttttcccttt gtggtttgtg tattttttgt gttttgtttg ttttttttta tattgttcaa
2581 tttaaaaaat ttagaaaatt ttaaccttac gttttcacat agtgtgatta gccaaaagga
2641 atttcacttc aagatctaga aatagaattc ataacatttt ttcctaaact ttgactttta
2701 aaacaacgaa aattaccaca tgagatgaac aagaaaattc attagaaagt tctctgggtg
2761 atttttggtg ctgaactgac atgagcctca tagactgtaa aacagaggta gttgaaacta
2821 atgtacagaa ctacattttt taattttatt tgcatttaat tctgtgaagt ttcagttatc
2881 taaaataaac acataaacgt gtaatgtttc agattgcaag gtgagatgta atgtagcatt
2941 tgtaagatat tcttgtcaat attaactggt aggattttga tttgtacagt tttaattggt
3001 taaaatgatc tcattttaac atccactgct atagatgaat gatgtaagct cagatttaat
3061 gaatggtggg gaaatggtgc atgtaatttt ttcgcaagta tcgagagttc tgtatgtttt
3121 gaaaagaata atttaacgtt tgggttgcca ggaagggggc tttcccagag tccattgcca
3181 ggcgttgggc aagcctcgca atgttggcac ggagcgttaa ccacacctta ctaatagcaa
3241 ggggaataac tttgaaataa agttttagac aaata
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