GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATCONN43 2768 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat heart mRNA for gap junction protein connexin43
ACCESSION X06656
KEYWORDS connexin; connexin43; gap junction protein;
integral membrane protein.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2768)
AUTHORS Beyer,E.C., Paul,D.L. and Goodenough,D.A.
TITLE Connexin43: A Protein from Rat Heart Homologous to a Gap Junction
Protein from Liver
JOURNAL J. Cell Biol. 105, 2621-2629 (1987)
STANDARD full automatic
COMMENT SWISS-PROT; P08050; GAP1$RAT.
*source: tissue=heart; library=cDNA in lambda gt11; *source: clone=
D7, G1, G2, G3; authors suggest term "connexin" for gap junction
integral membrane protein (hexamer complex)
Data kindly reviewed (27-May-1988) by Beyer E.C
From EMBL entry RNCONN43; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 202..1347
/note="connexin43 (AA 1-382)"
/codon_start=202
BASE COUNT 735 a 634 c 637 g 762 t
ORIGIN
1 ggcttttacg aggtatcagc acttttcttt cattgggggg aaggcgtgag gaaagtacca
61 aacagcagca gacttttaaa ctttaaacag acaggtctga gagcctgaac tctcattttt
121 cctttgactt cagcctccaa ggagttccac caactttggc ggcggcttca ctttcattaa
181 gtgaaagaga ggtgcccaga catgggtgac tggagtgcct tggggaagct tctggacaag
241 gtccaagcct actccaccgc tggagggaag gtgtggctgt cagtgctctt catattcaga
301 atcctgctcc tggggacagc tgttgagtca gcttggggtg atgaacagtc tgcctttcgc
361 tgtaacactc aacaacctgg ctgcgaaaac gtctgctatg acaagtcctt ccccatctct
421 cacgtgcgct tctgggtcct tcagatcata ttcgtgtctg tgcccaccct cctgtacttg
481 gcccatgtgt tctatgtgat gaggaaggaa gagaagctaa acaagaaaga agaggagctc
541 aaagtggccc agactgacgg ggtcaacgtg gagatgcacc tgaagcagat tgaaatcaag
601 aagttcaagt acgggattga agagcacggc aaggtgaaaa tgaggggcgg cttgctgaga
661 acctacatca tcagcatcct cttcaagtct gtcttcgagg tggccttcct gctcatccag
721 tggtacatct atgggttcag cttgagcgcg gtctacacct gcaagagaga tccctgcccc
781 caccaggtag actgcttcct ctcacgtccc acggagaaaa ccatcttcat catcttcatg
841 ctggtggtgt ccttggtgtc tctcgctttg aacatcattg agctcttcta cgtcttcttc
901 aaaggcgtta aggatcgcgt gaagggaaga agcgatcctt accacgccac cactggccca
961 ctgagcccat caaaagactg cggatctcca aaatacgcct acttcaatgg ctgctcctca
1021 ccaacggctc cactctcgcc tatgtctcct cctgggtaca agctggttac tggtgacaga
1081 aacaattcct cgtgccgcaa ttacaacaag caagctagcg agcaaaactg ggcgaactac
1141 agcgcagagc aaaatcgcat ggggcaggcc ggaagcacca tctccaactc gcacgcccag
1201 ccgttcgatt tccccgacga caaccagaat gccaaaaaag ttgctgctgg acatgaactc
1261 cagccattag ccatcgtgga ccaacgacct tccagcagag ccagcagccg cgccagcagc
1321 aggcctcggc ctgatgacct ggagatttaa accggcttga gcatcgagct gtcgattatg
1381 gaggagaaaa aaaggtgctt gcagaacatg cacctagggt gttcattttc gttcccgtgg
1441 agttggtact caacaacctc agcaatgagg ccatagaaaa caaagacatt acaataccta
1501 ggttccttgg gggtgcttgg gatagctggg cgaacaggtg gggataaggg aggtacacat
1561 tgatatttaa tgtagaagat tcaaagaact taaattctag taagagtcgc attgggtgaa
1621 catagataag ggctttctct ctctgccccc atcccccaac tgaaccttaa gaatgagtct
1681 gtgtattgtg tgtgtttgtg tgtgtgtgtg attattcatc agtcactgag cattaaactt
1741 tcctgtcttg actattataa aagatgtaca cttgagaatg tggatatctc tttgagatcc
1801 tgatttcaac tcttttctga aagtattgaa atgtaatgtc actcagtcat gtgtcagctc
1861 tggttttact ttttgaaaga cttttataat ccctggccta ggattgcacc attttatgtt
1921 acgttcaaca gagcactgaa gtccaatctc accgtcaata ccttactaat acacatgttt
1981 actttctaag catttgattt tacttaacac agagagagag agagacagag agagagacag
2041 acagagagag agagagagag agagagagag agagagagag agatgcacat acatgtatct
2101 atgaagtcca gaagaggggg taggatctcc tggagctgga gttacatgtg tttctgagct
2161 gctcagttta aatgctggaa cagaacccag gtcctctgtg agggcagaat ggctcttaat
2221 ctctgagtcc tctctccagc ccccacttct ttcctttcat actagctgtg ctgacgagca
2281 tgaagtaata ctttcttgga gccgtgtagc tgtggattat gctaatttag taagtgatgg
2341 tttgtggttc tctcacatcc atgagttcac taaccctgaa tagttagcta ggttttcagt
2401 aggaagcctg gtttccattt tgttgagtgg atttcaagtc ccattaggag ctattggtta
2461 caccaaccat gccattgcta caccctaaca gttactgcac cagatcaaca acgaaaagca
2521 ggtttctcat tcctgaaatt gaaggatttt gttaggtgat ctttgactct tgatcattgt
2581 cagcccagat aagaagattt tatttaaact acatatgaat atttatacac acaattattc
2641 ttattatact ttttatttat aattgcttat atttatttat aagtttttat ttacatttgt
2701 ggttaataga atgattcctt ataacctttt cagatatcct tattgttaat ttacctccat
2761 cctcttcc
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