GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATCP45AS 2693 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for aldosterone synthase cytochrome P-450
ACCESSION X52766
KEYWORDS cytochrome P-450.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2693)
AUTHORS Imai,M.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 2693)
AUTHORS Imai,M., Shimada,H., Okada,Y., Matsushima-Hibiya,Y., Ogishima,T.
and Ishimura,Y.
TITLE Molecular cloning of a cDNA encoding aldosterone synthase
cytocchrome P-450 in rat adrenal cortex
JOURNAL FEBS Lett. 263, 299-302 (1990)
STANDARD full automatic
COMMENT *source: tissue=adrenal gland
From EMBL entry RNCP45AS; dated 09-NOV-1990.
FEATURES Location/Qualifiers
CDS 1..1500
/note="aldosterone synthase cytochrome P-450 precursor"
/codon_start=1
CDS 1..72
/note="transit peptide"
/codon_start=1
CDS 73..1500
/note="mature aldosterone synthase cytochrome P-450"
/codon_start=73
BASE COUNT 681 a 656 c 722 g 634 t
ORIGIN
1 atggctctca gggtgacagc agatgtgtgg ctggcaagac cctggcagtg cctgcacagg
61 acgagggcac tgggcactac ggcaacactg gcccctaaga cactgaagcc ctttgaagcc
121 ataccacaat actccaggaa caagtggctg aagatgatac agatcctgag ggagcagggc
181 caagagaacc tacacctgga gatgcaccag gccttccagg agctggggcc cattttcagg
241 cacagtgcag ggggagcaca gattgtgtct gtgatgctgc ctgaggacgc tgagaagctg
301 caccaggtgg agagtatcct cccgcgtcgg atgcacctgg agccgtgggt ggcccacagg
361 gaactccgtg gcctgagacg tggtgtgttc ttgctaaatg gggctgaatg gcgcttcaac
421 cgactgaaac tgaacccaaa cgtgctgtca ccaaaagctg ttcaaaattt tgtccccatg
481 gtggacgagg tagcaaggga cttcttggag gccctgaaaa agaaggtgcg tcagaatgct
541 cgagggagcc ttaccatgga tgtccagcaa agtctcttca actacactat agaagccagc
601 aactttgcac tttttggaga gaggctgggc ctccttggtc atgacctgaa ccctggtagc
661 ctgaagttca tccatgccct acattcaatg ttcaagtcca ccacacagct cctgttctta
721 cccagaagct tgactcgctg gacaagcacc caggtgtgga aagaacattt tgatgcctgg
781 gatgtcatct ctgagtatgc caacagatgt atctggaagg tgcaccagga actcagactc
841 ggcagctctc agacctacag tggcattgtg gcagcactaa taactcaggg agctttacct
901 ctggacgcca tcaaagccaa ctctatggag ctcactgctg ggagcgttga cacgacagca
961 atccccttgg taatgacact ttttgagctg gctcggaacc cagatgttca gcaggccctg
1021 cggcaggaga ccctggcagc tgaggccagc atcgctgcta atccccagaa ggccatgtca
1081 gacctgccct tgctgcgggc tgcccttaaa gagaccttga gactctaccc tgttggtggc
1141 tttttggaga gaatcctaaa ctcagacctg gtgcttcaga actatcatgt ccctgctggg
1201 acgttggtcc tactttatct gtactccatg ggccgaaacc ctgcagtgtt cccaagacct
1261 gagcgctata tgcctcagcg ctggctggag aggaaaagga gtttccagca tctggccttc
1321 ggctttgggg tgcgccagtg cctggggcgg cgcctggcag aggtggagat gctgctcctg
1381 cttcaccata tgctgaaaac cttccaggtg gagacactga gacaagagga tgtgcagatg
1441 gcctatcgct ttgttttgat gcccagctct agtcctgtcc tcactttccg gcccatcagc
1501 tagtcacctt acatctgggg ccctaatcag tccaccggcc tacttctgtc ctgacgccca
1561 aggtcacgct tctctgccag cagaaatctt ggggggggga agaggtcaca ttgtcatcat
1621 tcaacacaac tgtacacagt ttacagctga agacctccag catcaggtac aagcaaggcc
1681 agggaagaga ttaggagtat cttcagggca ataggtagtc tctcctgagc ggtcttcccc
1741 attctttcca acggtcactc caggtggcca cggccttcaa agggtctcag agtaaagcca
1801 gaagtaatct cctccttatg gatccattat tttgacatga cccacaaaaa cattttcaca
1861 cacagatggg tttttggggg gcaaaagata catagatgat agatatgata tatgatattg
1921 atagatagat agatgataga tagatagata gatagataga tagatagata gatagataga
1981 tgatggatga ccagtcattt atgtctgtgt tttgtttgaa gcctttcaca gtggagctgg
2041 cacatatgag ttggtgactc tacagtgttt taagagtaga cacagctgca cttgctaagg
2101 actgggtggt tgtggtatca gagatgcagg caggaggacc tgctggaacc cagatagtgt
2161 gtgaagtccc cacagggacg gtggtcttcc atgaggtcaa ggtgttttcc tgacttctgc
2221 cagtgcatgc tgcttgggca aaggtaattc tcttgacttg tgaaagtggc ccaaagcata
2281 agaatttttt caggtatcct ttcagctgca agtcggtagg gcgaaaagtt ttggccaaga
2341 acaaccactt cacaggatct cctgtgctca gcaccaaagc acaaatctac tggagatgtg
2401 tgtgccaaat tccaaggtct taggcctttg agtgtgaggc agtatagagt cagggccttt
2461 aatgatataa ttcgtgtgaa atgagattac tgggttgtgc ctactccaat gcccagagag
2521 cacccaagaa gagagtgagg tgccaggtca cagagacaga ccccatgtgg aagacaggaa
2581 gtcagacttc tgtagccgag gaaagcagtt ggaactcctg tagtcttggc tccatcactc
2641 aatcacttcc ctggctgtga aaaataaact tgtgttgttg aagtcccaaa aaa
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