GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATFIBRON 8329 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for fibronectin.
ACCESSION X15906
KEYWORDS alternative splicing; extracellular protein; fibronectin;
glycoprotein.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 8329)
AUTHORS Schwarzbauer,J.E., Patel,R.S., Fonda,D. and Hynes,R.O.
TITLE Multiple sites of alternative splicing of the rat fibronectin gene
transcript
JOURNAL EMBO J. 6, 2573-2580 (1987)
STANDARD full automatic
REFERENCE 2 (bases 1 to 8329)
AUTHORS Hynes,R.O.
JOURNAL Unpublished (1989)
STANDARD full automatic
COMMENT *source: strain=fisher; tissue=liver; See m11750 for exon 5
sequence See k01269 for previously reported RNA sequence See
X05831-34 for genomic seqs x15906 reflects the longest form of
fibronectin mRNA. Some segments are omitted in some mRNAs.
From EMBL entry RNFIBRON; dated 13-SEP-1990.
FEATURES Location/Qualifiers
mRNA 1..8329
/note="transcript"
CDS 208..7638
/note="precursor polypeptide (AA -32 to 2445)"
/codon_start=208
CDS 208..303
/note="signal peptide (AA -32 to -1)"
/codon_start=208
CDS 304..7638
/note="fibronectin (AA 1 to 2445)"
/codon_start=304
misc_feature 8308..8313
/note="pot. polyA signal"
polyA_site 8329..8329
/note="polyA signal"
BASE COUNT 2120 a 2348 c 2100 g 1761 t
ORIGIN
1 ctcgcacccg ctgcactgca caggggaaga aaaggagccc agggtgtgag ccggccagcg
61 gccacaactt ctggtcctct cccgtgtcct ccttccatct tcttacaggc gtccccacct
121 caggactttt cctgcaggct gcgaggggaa ccaacttcgt ggccactagc ctcctggaga
181 gggcgactct cctcccatcc actcaagatg ctcaggggtc cgggacccgg gcggctgctg
241 ctgctagcag tcctgtgcct ggggacatcg gtgcgctgca ccgaaaccgg gaagagcaag
301 aggcaggctc agcaaatcgt gcagcctccg tccccggtgg ctgtcagtca gagcaagcct
361 ggctgttttg acaacgggaa gcattatcag ataaatcagc agtgggaacg gacctaccta
421 ggcaacgccc tggtttgtac ctgctatgga ggaagcagag gttttaactg cgagagcaag
481 cctgaacctg aagagacctg ttttgacaaa tacactggaa acacttacaa agtgggtgac
541 acttatgagc gccctaaaga ttccatgatc tgggactgta cctgcattgg ggctgggcga
601 ggcaggatca gctgtaccat tgcaaatcgc tgccatgaag ggggtcagtc ctacaagatt
661 ggtgacaagt ggaggaggcc acatgagact ggtggctata tgttggagtg tttgtgtctg
721 gggaatggaa aaggggaatg gacctgcaag ccaatagctg agaaatgttt tgatcacgct
781 gctgggactt cctacgtcgt gggggagacc tgggaaaagc cctaccaagg ctggatgatg
841 gtggactgta cttgtctggg cgaaggcaat gggcgtatca cctgcacctc ccggaacaga
901 tgcaatgatc aggacaccag gacgtcctac agaattggag acacatggag caagaaggac
961 aacagaggga acctgctcca gtgtgtctgc acaggcaacg gcagagggga gtggaagtgt
1021 gagcgacatg ttctacagag tgcttcagct ggatctggct ccttcacaga tgtccgaaca
1081 gctatttacc aaccccagac ccacccccag cccgcaccgt acggccactg tgtcacagac
1141 agcggtgtgg tctactctgt gggaatgcag tggctgaagt ctcaaggaga caagcagatg
1201 ctgtgcactt gcctgggcaa tggcgtcagc tgccaggaga cagctgtgac ccagacttac
1261 ggtggcaact caaacgggga gccctgtgtt ctcccgtttc actacaacgg taggaccttc
1321 tactcctgca ccaccgaagg gcggcaagac ggacatctgt ggtgtagcac aacttcaaat
1381 tatgaacaag accagaagta ttctttctgc acagaccacg cggttttggt tcagactcga
1441 ggtgggaatt ccaatggtgc cttgtgccac ttccccttcc tgtacagcaa ccggaattac
1501 agcgactgta cttctgaggg taggcgggac aacatgaaat ggtgcggcac cacccagaac
1561 tacgatgccg atcagaagtt tggattctgc ccaatggctg cccatgagga gatctgcacg
1621 accaacgaag gggtcatgta tcgcattggg gaccagtggg ataagcagca tgacctgggc
1681 cacatgatga ggtgcacgtg tgttgggaac ggccgtggac aatgggcctg catcccctac
1741 tcccagctcc gagatcagtg catcgttgat gacattactt acaacgtcaa cgacacgttc
1801 cacaagcgtc acgaggaggg acatatgctg aactgtacct gcttcggtca gggccggggc
1861 agatggaaat gtgaccccat cgaccgatgc caagattcag agacccggac attttaccag
1921 attggtgact cctgggagaa gtttgtgcat ggtgtcagat accagtgtta ctgttacggc
1981 cgtggcattg gggagtggca ctgccagcct ctgcagacct acccaggcac aactggacct
2041 gttcaagtaa ttatcacgga gacccccagc cagcccaatt cccaccccat ccagtggaat
2101 gccccggagc cttcacacat caccaagtac attctcaggt ggagacctaa aacctctacg
2161 ggtcgctgga aggaagctac cattccaggc caccttaact cctataccat caaaggcctg
2221 accccaggtg tgatctacga gggacagctc atcagcatcc agcagtacgg gcaccaagaa
2281 gtgactcgct ttgacttcac caccagcgcc agcacacctg tgaccagcaa cacagtgact
2341 ggagagactg cgcccttttc tcctgttgtg gccacttccg aatctgtcac tgaaatcaca
2401 gccagcagct tcgtggtctc ctgggtctca gcttccgaca cggtgtcagg attccgagtg
2461 gagtacgaac tgagcgagga aggagatgag cctcagtacc ttgatcttcc aagcacagcc
2521 acttctgtga acattcctga cctgctcccg ggcagaaagt acatcgtcaa cgtctatcag
2581 atatctgaag agggaaagca gagcttgatc ctgtctacat cacagactac agcacctgat
2641 gcgcctccag accctactgt ggaccaggtt gatgacactt ccattgttgt tcgatggagc
2701 agaccccagg cacctatcac agggtacagg attgtctatt caccttcagt agaaggcagt
2761 agcacagaac tcaaccttcc tgaaacggcc aactccgtca ccctcagcga cctgcagccc
2821 ggtgttcagt acaacatcac tatctatgct gtggaggaga accaggagag cacacccgtt
2881 ttcatccagc aggagactac tggcgtccca cgatccgatg atgttcccgc tccaaaggac
2941 ctacagtttg tggaagtgac cgacgtgaaa gtcaccatca tgtggacacc tcctaatagc
3001 gcagtgactg gataccgtgt ggatgtcctg cctgtcaacc tgccagggga acatgggcag
3061 aggctgcctg tcaacaggaa cacctttgct gaagtcaccg gactgtcccc aggggtcacg
3121 tacctcttca aagtctttgc tgtgcatcag ggcagggaaa gcaagcctct gacagcacaa
3181 cagaccacca aactcgatgc tcccactaac ctccagtttg tcaatgaaac ggacagaaca
3241 gttctggtaa cttggactcc acctcgagcc cggatagcag gctaccgact gacagtgggc
3301 ctcacccgag gaggccagcc caagcagtac aatgtgggac ccatggcttc caagtatccc
3361 ctgagaaatc tgcagcctgg gtctgagtac actgtgacct tgatggctgt gaaaggcaac
3421 cagcagagtc ccaaagccac cggagtcttt actaccctgc agcctctgcg ctccattcca
3481 ccttataaca ccgaggtgac agagaccaca atcgtgatca cctggacccc cgctccaagg
3541 attggcttca agctgggtgt acgaccaagc cagggaggtg aagcaccccg agaagtgact
3601 tcagactcag gaagcatcgt tgtgtctggc ttgactccag gcgtggaata cacgtacacc
3661 atccaagtcc tgagggacgg ccaggagaga gatgcaccaa ttgtcaaccg agtagtgaca
3721 ccgctgtctc ccccaaccaa cttgcacctg gaggccaatc ctgacactgg agtgcttacc
3781 gtctcctggg agaggagcac caccccagat attactggct acagaataac caccaccccc
3841 acaaacgggc agcagggaac cgctttggaa gaagtggttc atgccgatca gagttcctgc
3901 acttttgaaa accgtaatcc tggcctggag tacaatgtca gtgtttacac tgtcaaagat
3961 gacaaggaaa gtgcccctat ctctgatacc gtcatcccag aggtgcccca gctcactgac
4021 ctaagctttg ttgatataac tgactcaagc atcggcctga ggtggacccc gctaaactct
4081 tccaccatta tcgggtaccg aatcacagta gttgcggcag gagaagggat ccccattttt
4141 gaagattttg tggactcctc agtaggatac tacacagtta cagggctgga acccggcatt
4201 gactatgaca tcagcgttat cactctcatt aatggcggag agagtgcccc tactacactg
4261 acacagcaaa cggccgtccc tcctcccacg gatctgcgat tcaccaatat cggtccggac
4321 actatgcggg tcacttgggc cccgcctccg tccattgagc taaccaacct cttggtgcgc
4381 tactcacctg tgaagaacga ggaggatgtg gcagagctgt ccatttcacc ctcagacaac
4441 gccgtggtcc taacaaatct cctgcctggg actgagtacc tagtcagtgt ctccagcgtg
4501 tacgaacagc atgagagcat acctctcaga ggaagacaga aaacaggtct ggactcccca
4561 actggttttg attcttctga tgtcaccgcc aactcattca ccgtccactg ggtggctcct
4621 cgggccccca tcaccggcta catcatccgc catcacgccg agcattctgc cggaagaccc
4681 aggcaagacc gagtgccgcc ctcaaggaat tctatcaccc tcaccaacct taatccgggc
4741 acggagtaca ttgtcaccat cattgctgtt aatggcagag aggagagccc cccactgatt
4801 ggccagcaat ccacggtttc cgatgtcccg agagatctgg aggtcatcgc ttccaccccc
4861 accagcctgc tcatcagttg ggaacccccc gccgtctctg tgcgctatta cagaatcacc
4921 tatggagaga caggaggaaa tagccctgtc caggaattca ctgtgcccgg aagcaagtcc
4981 accgccacca tcaacaacat taaaccagga gcagactaca ccatcaccct gtatgctgtc
5041 actggccgtg gggacagtcc agccagcagc aagccagttt ccatcaatta tcaaacagaa
5101 attgacaagc catcccagat gcaggtgacg gatgtccagg acaacagcat cagtgtcagg
5161 tggctgcctt caacttctcc tgtgacaggt tacagagtga ccaccgctcc caaaaatggc
5221 ctaggaccaa caaaatctca aactgtcagt ccagatcaaa cagaaatgac cattgaaggt
5281 ttgcaaccca ccgtggagta tgtggttagt gtctatgctc agaaccggaa cggagaaagc
5341 cagcccctgg ttcagactgc agtgaccaac attgaccgcc ctaaaggact ggcattcact
5401 gatgtggatg tcgattccat caaaattgcc tgggaaagcc cacaggggca agtttccagg
5461 tacagggtga cctactcaag ccctgaggat ggaatccatg agcttttccc tgcgcctgat
5521 ggtgacgagg acacggcaga gctgcacggc ctcaggccgg gttctgagta cacagtcagt
5581 gtggttgcct tgcacggtgg catggagagc cagcccctga ttggagtcca gtccacagcc
5641 attcctgcgc caaccaatct gaagttcact caggtgtcac ccaccacctt gactgcccag
5701 tggacagcgc ccagtgttaa gctcactggc taccgagtgc gggtgacccc gaaggagaag
5761 acaggaccaa tgaaagaaat caacctttct ccagacagca cctccgtgat tgtgtcaggg
5821 ctcatggtgg ccaccaagta tgaagtcagc gtctatgctc tcaaggacac attgacaagc
5881 agaccagctc agggagtcgt cacgactctg gagaatgtca gccctccaag aagggcccgt
5941 gtgaccgacg ctacagaaac taccatcact attagctgga gaacgaagac agagacgatc
6001 actggcttcc aagtcgatgc cattccagcc aatggccaga ccccggttca gaggaccatc
6061 agcccggatg tcagaagcta tactattaca ggtttacagc caggcactga ctacaagatc
6121 cacctgtaca cgctcaacga caatgcccgg agctctcctg tggtcattga tgcctccacg
6181 gccattgatg ccccatccaa cctgcggttc ctgaccacca cacccaactc cttgctggta
6241 tcatggcagg caccccgtgc caggattact ggctacatta tcaagtatga gaagcctgga
6301 tcccctccca gagaagtggt ccctcggccc cgccctggtg tcacggaggc caccatcact
6361 ggtctggagc caggaaccga gtacaccatc tatgtcatcg cactgaagaa caatcagaag
6421 agtgagcccc tgattgggag gaaaaagaca gatgagcttc cccaactggt tacccttcca
6481 caccccaatc ttcatggacc agagatcttg gatgttccct ccacagttca aaagaccccc
6541 ttcgtcacca accctgggta tgacaccgaa aatggtattc agcttcctgg cacatcccac
6601 caacaaccca gtgttgggca acaaatgatc tttgaggaac atggctttag gcgaaccacg
6661 ccacccactg cggccacccc cgtcaggctt aggccaagac catacctgcc gaatgtagat
6721 gaggaggtcc aaatcggtca tgttcccagg ggagacgtag actaccacct ctatcctcat
6781 gttccggggc tcaatccaaa tgcctctaca ggacaagaag ctctctctca gacaaccatc
6841 tcttggacgc cattccagga gagttctgag tacatcattt catgccaacc tgttggcact
6901 gacgaagagc ccttacagtt ccaagttcct ggaacttcta ccagtgcgac tctgactggc
6961 cttaccagag gggtcaccta caacatcata gtggaggccc tgcacaacca gaggaggcac
7021 aaggtccgag aagaggttgt tactgtaggc aacactgtca acgaaggcct gaaccagcct
7081 acggatgact catgctttga cccttacacg gtttcccatt acgccgttgg agaggaatgg
7141 gagcggttat ctgactctgg ctttaagctc acttgccagt gcttgggctt tggcagtggt
7201 catttcagat gcgattcatc taaatggtgc catgacaacg gtgtcaacta caagatcgga
7261 gagaagtggg atcgtcaggg agaaaatggc cagcggatga gctgcacatg tctcgggaat
7321 ggaaagggag aattcaaatg cgatccccat gaagcaacgt gttatgacga cgggaagacc
7381 taccacgtag gagaacagtg gcagaaagag tatctcggag ccatttgctc ctgcacgtgt
7441 ttcgggggcc agcggggctg gcgctgtgac aactgccgca gacctggggc tgctgaaccc
7501 agtcccgatg gtaccactgg ccacacctac aaccagtata cacagagata ccatcagaga
7561 acgaacacta atgtaaattg cccaattgaa tgcttcatgc cgttggacgt gcaggctgac
7621 agagatgatt ccagagagta atctttccat ccagcccaag ccaacaagtg tctctctacc
7681 aaggtcaatc cacaccccag tgatgttagc agaccctcca tttctgagtg gtcatttcac
7741 ccttaagcct tctgctctgg agtcaagttc tcagcttcag ctcaacttac agcttctcca
7801 agcatcgccc cgcgggatgt tttgagactt ccctcttaaa tggtgacagt tggtgccctg
7861 ttctgcttca gggtattcag tactgctcag tattattgtc taagagaatc aaaagttctt
7921 gtgatttggt ctgggatcaa agggaaacac aggtagccaa ccacgatgca atgaattgaa
7981 tggtagtacc caagagcggg agcaggaagt taaaccagac agttctgctt tcttttgccg
8041 tctgatctgc agcactgtca ggaggcctgt cctgtggctg tgtccaaaca ccccacagga
8101 ctcactgtcc caacaatcct aattgcctag aaatatcttt ctcttacctg ttatttatca
8161 atttttccca gtatttttat acggaaaaaa ttgtattgaa gacactttgt atgcagttga
8221 taagaggaat tcagtataat tatggttggt gactattttt ataatgtaca tgccaacact
8281 ttactactgt ggaaagacaa gtgttttaat aaaaagattt acattccat
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