GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATGROW2 2243 bp ds-DNA ROD 2
DEFINITION Rat gene for growth hormone (presomatotropin).
ACCESSION V01238
KEYWORDS germline; growth hormone; signal peptide.
SOURCE Rattus norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2243)
AUTHORS Page,G.S., Smith,S. and Goodman,H.M.
TITLE DNA sequence of the rat growth hormone gene: location of the 5'
terminus of the growth hormone mRNA and identification of an
internal transposon-like element
JOURNAL Nucleic Acids Res. 9, 2087-2104 (1981)
STANDARD full automatic
COMMENT This entry was previously named <RNGROWZ1>.
See also entries <RNGROW1> and <RNGROW3>.
Two 200bp direct repeats are flanked by two 15bp direct repeats in
IVS 2.
From EMBL entry RNGROW2; dated 06-JUL-1989.
FEATURES Location/Qualifiers
precursor_RNA 230..2210
/note="presomatotropin"
CDS 290..299
/note="reading frame (299 is 1st base in codon)"
/codon_start=290
intron 300..484
/note="ivs 1"
CDS 485..645
/note="reading frame (485 is 2nd base in codon)"
/codon_start=485
intron 646..1259
/note="ivs 2"
CDS 1260..1376
/note="reading frame"
/codon_start=1260
intron 1377..1534
/note="ivs 3"
CDS 1535..1696
/note="reading frame"
/codon_start=1535
intron 1697..1908
/note="ivs 4"
CDS 1909..2106
/note="reading frame"
/codon_start=1909
polyA_site 2210..2210
/note="poly A addition site"
BASE COUNT 553 a 605 c 573 g 512 t
ORIGIN
1 cgtaccattg cccataaact tggcaaaggc ggcggtggaa aggtaagatc agggacgtga
61 ccgcaggaga gcagtgggga cgcgatgtgt gggaggagct tctaaattat ccatcagcac
121 aagctgtcag tggctccagc catgaataaa tgtataggga aaaaggcagg agccttgggg
181 tcgaggaaaa caggtagggt ataaaaaggg catgcaaggg accaaatcca gcaccctcga
241 gcccagattc caaactactc aggtcctgtg gacagatcac tgagtggcga tggctgcagg
301 taagcatgcg cagatcccgc tgggtgtggt ttggaccaaa gagccttgaa gatggatctg
361 aggcttctag tgtgagggca tcccaacttc cgcccatgtt gggaacattc tgggacccta
421 tggggattgg gagagattgg tccttgctcc cagcctcctc ctgtcctcct gtctctcttt
481 ctagactctc agactccctg gctcctgacc ttcagcctgc tctgcctgct gtggcctcaa
541 gaggctggtg ctttccctgc catgcccttg tccagtctgt ttgccaatgc tgtgctccga
601 gcccagcacc tgcaccagct ggctgctgac acctacaaag agttcgtaag ttcctcggtg
661 ttgggtgcct gactgtggaa gcaggaaagg ggcacgatcc caccctcgcc ccgaatccct
721 gcccccagga agtcatagga ggaaactatg ccgttagatg agcagaaaaa gaatgggtcg
781 tccataagca gtaatgacag agagggctgg agagatggct cagtggttaa gagcacccga
841 ctgctcttcc aaaggtcctg agttcaattc ccagcaacca catggtggct cacaaccatc
901 tgtaaagaga tccgatgccc tcttctggtg tgtctgaaga cagctacagt gtacttatat
961 aataaacaaa taaatcttta aaaaaaaaaa caaaaacggg gctggagaga tggctcagcg
1021 gttaagagcg cccgactgct cttccagagg tcatgagttc aattcccagc aaccacatgg
1081 tggctcacaa ccatctgtaa agagatctga tgccctcttc tggtgtatct gaagacagct
1141 acagtgtact tatatataat aaataaataa atctttaaaa aaaacaaaac aaaaacaaaa
1201 acaaaacagt aatgacagag agtcacaagc tggtccctca gtgactacct ttcctccagg
1261 agcgtgccta cattcccgag ggacagcgct attccattca gaatgcccag gctgcgttct
1321 gcttctcaga gaccatccca gcccccaccg gcaaggagga ggcccagcag agaactgtga
1381 gtaggcccag gccttgtctg tacagatcct cttttcttcc caagcagccc taactgcagt
1441 ccaggccagg gaccagctct tccctgaggc tgaggtaacc tgggagtccc aggcagaggt
1501 cactagctaa tgcacagccc cttttttccc tcaggacatg gaattgcttc gcttctcgct
1561 gctgctcatc cagtcatggc tggggcccgt gcagtttctc agcaggatct ttaccaacag
1621 cctgatgttt ggtacctcgg accgcgtcta tgagaaactg aaggacctgg aagagggcat
1681 ccaggctctg atgcaggtca ggatggaccg ggggcgctag cctgaggtta tactgacctt
1741 tgcctctgct tggagcctag ctggggggct cactgagctc tgtttaccgg tcagacctta
1801 aaccttgaga aggcttccta ctcactttcc cttatgaagc ctccaggcct ttctctaggt
1861 tctggagttg gggagggcac ggctctgagt tcttctttcc cacaacagga gctggaagac
1921 ggcagccccc gtattgggca gatcctcaag caaacctatg acaagtttga cgccaacatg
1981 cgcagcgatg acgctctgct caaaaactat gggctgctct cctgcttcaa gaaggacctg
2041 cacaaggcag agacctacct gcgggtcatg aagtgtcgcc gctttgcgga aagcagctgt
2101 gctttctagg cacacactgg tgtctctgcg gcactccccc gttacccccc tgtactctgg
2161 caactgccac ccctacactt tgtcctaata aaattaagat gcatcatatc actctgctag
2221 acatcttttt tttttttgaa ggc
//GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATGROW3 2557 bp ds-DNA ROD 28-MAY-1991
DEFINITION Rat gene for growth hormone (presomatotropin).
ACCESSION V01239
KEYWORDS germline; growth hormone; signal peptide.
SOURCE Rattus norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2557)
AUTHORS Barta,A., Richards,R.I., Baxter,J.D. and Shine,J.
TITLE Primary structure and evolution of rat growth hormone gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 78, 4867-4871 (1981)
STANDARD full automatic
COMMENT EPD; 07104; Rn growth hormone.
See also entries <RNGROW1> and <RNGROW2>.
From EMBL entry RNGROW3; dated 06-JUL-1989.
FEATURES Location/Qualifiers
precursor_RNA 401..2487
/note="presomatotropin"
CDS 461..470
/note="reading frame (part 1) (470 is 1st base in codon)"
/codon_start=461
intron 471..655
/note="first intron"
CDS 656..816
/note="reading frame (part 2) (656 is 2nd base in codon)"
/codon_start=656
intron 817..1335
/note="second intron"
CDS 1535..1651
/note="reading frame (part 3)"
/codon_start=1535
intron 1652..1810
/note="third intron"
CDS 1811..1972
/note="reading frame (part 4)"
/codon_start=1811
intron 1973..2185
/note="fourth intron"
CDS 2186..2383
/note="reading frame (part 5)"
/codon_start=2186
BASE COUNT 646 a 672 c 648 g 591 t
ORIGIN
1 tcaacaaatt aagaggaata agacaatcat ggggaaaata cctccttgga gaggctctgt
61 tgcccctcgt cccagtgaac aaacgatggt accctgccag agtatcctac ccctggattc
121 aaaaatactc tcaaaaggac acattgggtg gtctctgtag ctgagatctt gcgtgaccat
181 tgcccataaa cctgagcaaa ggcggcggtg gaaaggtaag atcagggacg tgaccgcagg
241 agagcagtgg ggacgcgatg tgtgggagga gcttctaaat tatccatcag cacaagctgt
301 cagtggctcc agccatgaat aaatgtatag ggaaaggcag gagccttggg gtcgaggaaa
361 acaggtaggg tataaaaagg gcatgcaagg gaccaagtcc agcaccctcg agcccagatt
421 ccaaactgct caggtcctgt ggacagatca ctgagtggcg atggctgcag gtaagcatgc
481 gcagatcccg ctgggtgtgg tttggaccaa agagccttga agatggatct gaggcttcta
541 gtgtgagggc atcccaactt ccgcccatgt tgggaacatt ctgggaccct atggggattg
601 ggagagattg gtccttgctc ccagcctcct cctgtcctcc tgtctctctt tctagactct
661 cagactccct ggctcctgac cttcagcctg ctctgcctgc tgtggcctca agaggctggt
721 gctttccctg ccatgccctt gtccagtctg tttgccaatg ctgtgctccg agcccagcac
781 ctgcaccagc tggctgctga cacctacaaa gagttcgtaa gttcctcggt gttgggtgcc
841 tgactgtgga agcaggaagg ggcagatccc accctcgccc cgagtccctg cccctaggaa
901 gtcataggag gaaactatgc cgttagatga gcagaaacag aatgggtcgt ccataacagt
961 aatgacagag agggctggag agatggctca gtggttaaga gcacccgact gctcttccaa
1021 aggtcctgag ttcaattccc agcaaccaca tggtggctca caaccatctg taaagagatc
1081 cgatgccctc ttctggtgtg tctgaagaca gctacagtgt acttatataa taaacaaata
1141 aatctttaaa aaaaaaaaca aaaacggggc tggagagatg gctcagcggt taagagcgcc
1201 cgactgctct tccagaggtc atgagttcaa ttcccagcaa ccacatggtg gctcacaacc
1261 atctgtaaag agatctgatg ccctcttctg gtgtatctga agacagctac agtgtactta
1321 tatataataa ataaataaat ctttaaaaaa aaacaaaaca ggggctgggg atttagctca
1381 gtggtagagc gcttacctag gaagcgcaag gccctgggtt cggtccccag ctccgaaaaa
1441 aagaaccaaa aaaaaaaaaa aaaaccaaaa caaaaacaaa acagtaatga cagagagtca
1501 caagctggtc cctcagtgac tacccttcct ccaggagcgt gcctacattc ccgagggaca
1561 gcgctattcc attcagaatg cccaggctgc gttctgcttc tcagagacca tcccagcccc
1621 caccggcaag gaggaggccc agcagagaac tgtgagtagg cccaggcctt gtctgtacag
1681 atcctctttt cctccccaag cagccctaac tgcagtctag gccagggacc agctcttccc
1741 tgaggctgag gtaacttggg agtcccaggc agaggtcact agctaatgca cagccccttt
1801 tttccctcag gacatggaat tgcttcgctt ctcgctgctg ctcatccagt catggctggg
1861 gcccgtgcag tttctcagca ggatctttac caacagcctg atgtttggta cctcggaccg
1921 cgtctatgag aaactgaagg acctggaaga gggcatccag gctctgatgc aggtcaggat
1981 ggaccggggg cgctagcctg aggttatact gacctttgcc tctgcttgga gcctagctgg
2041 ggggctcact gagctctgtt taccggtcag accttaaacc ttgagaaggc ttcctactca
2101 ctttccctta tgaagcctct aggcctttct ctaggttctg gagttgggga ggggcacggc
2161 tctgagttct tctttcccac aacaggagct ggaagacggc agcccccgta ttgggcagat
2221 cctcaagcaa acctatgaca agtttgacgc caacatgcgc agcgatgacg ctctgctcaa
2281 aaactatggg ctgctctcct gcttcaagaa ggacctgcac aaggcagaga cctacctgcg
2341 ggtcatgaag tgtcgccgct ttgcggaaag cagctgtgct ttctaggcac acactggtgt
2401 ctctgcggca ctcccccgtt acccccctgt actctggcaa ctgccacccc tacactttgt
2461 cctaataaaa ttaagatgca tcatatcact ctgctagaca tctttttttt tttaaggcgt
2521 ccggtttttt tttttagatt tatttattta ttataag
//