GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATMAP01 1390 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for major acute phase alpha-1 protein (MAP)
ACCESSION X02299
KEYWORDS bradykinin; glycoprotein; major acute phase protein.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1390)
AUTHORS Cole,T., Inglis,A.S., Roxburgh,C.M., Howlett,G.J. and Schreiber,G.
TITLE Major acute phase alpha1-protein of the rat is homologous to bovine
kininogen and contains the sequence for bradykinin: its synthesis
is regulated at the mRNA level
JOURNAL FEBS Lett. 182, 57-61 (1985)
STANDARD full automatic
COMMENT SWISS-PROT; P01048; KNT1$RAT.
Data kindly reviewed (23-Jul-1985) by T.Cole
The amino acid composition of rat low-Mr kininogen agrees closely
with that of MAP suggesting possible identity.
From EMBL entry RNMAP01; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS <1..36
/note="put. signal peptide"
/codon_start=1
CDS 37..1272
/note="major acute phase alpha-1"
/codon_start=37
CDS 1114..1140
/note="bradykinin sequence"
/codon_start=1114
misc_feature 1366..1370
/note="polyadenylation signal"
polyA_site 1390..1390
/note="polyadenylation site"
BASE COUNT 403 a 328 c 345 g 314 t
ORIGIN
1 gtgctcctct gctccaggct cctgccaagt ttagcgcagg aagaaggcgc ccaggaattg
61 aactgcaatg atgagactgt atttcaggct gtggatactg ctctgaagaa atataacgct
121 gagttagaaa gcggcaacca gtttgtgttg taccgagtga ctgagggcac taagaaggat
181 ggcgctgaaa cattgtattc cttcaagtat caaatcaagg agggcaactg ctctgttcag
241 agtggcctca cctggcagga ctgtgacttc aaggacgctg aggaagccgc tactggcgaa
301 tgcacaacaa ctttggggaa gaaagaaaat aaattctccg tagccaccca gatctgcaat
361 attactccag gtaagggtcc taagaagaca gaggaggacc tctgtgtcgg gtgtttccaa
421 cccataccga tggatagctc agacctgaag cctgttctga aacacgctgt ggagcatttc
481 aacaacaaca cgaagcacac ccacctcttt gctctcagag aagtaaagag tgcccactca
541 caggtggtgg ctggcatgaa ttataaaatt atctactcca ttgtgcaaac aaattgttca
601 aaggaggatt ttccttccct ccatgaagac tgtgtacccc ttccctatgg cgatcatggt
661 gagtgtacgg gtcataccca cgtggatatt cataacacaa ttgccggctt ctcacagagc
721 tgtgaccttt atccaggaga tgatttgttt gaactacttc ccaagaattg ccgtggctgc
781 cccagggaga tacctgtaga cagcccggag ctgaaggagg cacttggtca ttccattgcg
841 agacttaatg cacagcataa ccatattttc tatttcaaga ttgacaccgt gaaaaaggca
901 acatcacagg tggttgctgg agtaatatat gtgattgagt tcatagccag agaaactaac
961 tgttccaagc aaagtaaaac agaactgaca gcggattgtg agaccaaaca cctcggtcaa
1021 agcctcaact gcaatgctaa cgtgtacatg agaccttggg agaacaaagt cgtcccgact
1081 gtcagatgcc aagcactaga tatgatgatt tctaggcctc caggattttc acctttccgg
1141 ctggtgcgag tacaagaaac taaagaagga acgactaggc tcctaaactc atgtgagtac
1201 aagggcagac tctcaaaggc aggggcaggc ccagcacctg agcgtcaggc agaagcttca
1261 accgtgacac catagcccgg caaagacccg gagtggaagg accagaagac tcctgggatg
1321 tgtgcagcat ggaagcatgt ttcttcatca cctgatcctg ggtgaaataa agttcagact
1381 cgacgagttc
//