GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATPROTH 2045 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for prothrombin
ACCESSION X52835
KEYWORDS preprothrombin; prothrombin.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2045)
AUTHORS Dihanich,M.E.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 2045)
AUTHORS Dihanich,M.E. and Monard,D.
TITLE cDNA Sequence of Rat Prothrombin
JOURNAL Nucleic Acids Res. 18, 4251-4251 (1990)
STANDARD full automatic
COMMENT *source: strain=Sprague Dawley; tissue=liver; library=lambda-Zap
II; *source: developmental stage=7-8 weeks old; clone=RL11;
Data kindly reviewed (16-AUG-1990) by Dimanich M.
From EMBL entry RNPROTH; dated 01-OCT-1990.
FEATURES Location/Qualifiers
precursor_RNA <1..2045
/note="primary transcript"
CDS 81..1931
/note="preprothrombin (AA -43 to 574)"
/codon_start=81
CDS 81..209
/note="signal peptide (-43 to -1)"
/codon_start=81
CDS 210..1931
/note="mature prothrombin (AA 1-574)"
/codon_start=210
misc_feature 1011..1157
/note="thrombin A-chain"
misc_feature 1158..1931
/note="thrombin B-chain"
BASE COUNT 486 a 530 c 595 g 434 t
ORIGIN
1 ggctgtggtg accggaacaa gcccggggtc tacactgacg tggccaatta cctggattag
61 atcccaggag ctgacacact atgttgcacg tccgcggcct ggggctacct ggctgcctgg
121 ctctggctgc cctggctagc ctggtacaca gtcagcatgt gttcctggcc cctcagcaag
181 cactgtcgct gctccagcgg gtccgcagag ccaacagcgg cttcctggag gagctccgaa
241 agggcaacct ggagcgtgag tgcgtggaag agcagtgcag ctatgaggag gcttttgagg
301 ccctggagtc tccccaagac acggatgtgt tctgggccaa gtacacagtg tgtgattcag
361 tgaggaaacc tcgagagacc ttcatggact gtctagaagg tcgctgtgct atggatctgg
421 gtctgaacta ccatgggaat gtgagtgtca cccataccgg catcgagtgt cagctgtggc
481 gaagccgcta cccacacagg cctgacatca actccaccac ccatcctggg gctgacctga
541 aggagaactt ctgccgaaat ccagacagca gtacctcagg gccctggtgc tacaccacag
601 accctactgt gcgcagagag gaatgcagta tccctgtctg tggtcaggag ggccgtacca
661 ctgtgaaaat gactcctcgc tcaagaggtt ccaaggagaa tctgtcgcct ccattgggag
721 agtgcctcct cgagcgtggc cggctgtacc aggggaactt agctgtgaca acacttgggt
781 ccccctgcct ggcctgggac agtttgccaa ccaagaccct gagcaagtac cagaacttcg
841 accctgaggt gaaactcgtg caaaacttct gccgcaatcc agaccgggat gaggagggcg
901 cgtggtgctt tgttgcgcag cagcctggtt ttgaatactg cagcctcaac tactgtgatg
961 aagcggtggg agaggagaac catgacgggg acgagtccat cgcaggacgc accaccgacg
1021 cggagttcca caccttcttc gatgagagga ctttcggcct tggggaggca gactgtggcc
1081 tgcggccttt gttcgagaag aagtccttga cagacaaaac ggaaaaggag cttcttgatt
1141 cttacataga tgggcgcatc gtggagggct gggacgctga gaagggtatc gccccatggc
1201 aggtgatgct ttttcggaag agtccccaag agctgctgtg tggagccagc cttatcagtg
1261 atcgatgggt cctcactgct gcccactgca ttctgtaccc accctgggac aagaacttca
1321 ctgagaatga cctcctggtg cgcattggca agcactccag aaccagatat gagcggaatg
1381 ttgaaaagat ctccatgctg gaaaagatct acatccaccc cagatataac tggcgggaaa
1441 acctagaccg tgacattgct ctgctcaagc taaagaagcc agtgcccttc agtgactaca
1501 ttcaccccgt gtgcttgcca gacaagcaga cagtaaccag tttgctccag gctggttata
1561 aagggcgggt gacaggctgg ggcaaccttc gggagacgtg gacaaccaac atcaacgaga
1621 tacagcccag cgtcctgcag gtggtgaacc tgcccattgt agagcgacca gtgtgcaagg
1681 cctctacccg gatacgcatt actgacaaca tgttctgtgc tggcttcaag gtgaatgaca
1741 ccaagcgagg agatgcttgt gaaggtgaca gtgggggacc ttttgtcatg aagagcccct
1801 acaaccaccg ctggtaccaa atgggtattg tctcctgggg tgaaggctgt gaccggaatg
1861 ggaaatatgg cttctacacg cacgtgttcc gtctgaaaag gtggatgcag aaagtcattg
1921 atcagcatag ataggtttgt gggtgggtga gagacccaca gtatgggatc ctcattgcaa
1981 aatcacagaa accagttcaa aatatttttg tggtttgttt ctgttctcaa taaaagtgat
2041 tgtcg
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