GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATTGFB1 1585 bp ss-mRNA ROD 28-MAY-1991 DEFINITION Rat mRNA for transforming growth factor-beta 1 ACCESSION X52498 KEYWORDS TGF-beta 1; growth factor; transforming growth factor-beta 1. SOURCE Rattus norvegicus RNA. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 1585) AUTHORS Su,W.Q. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 1 to 1585) AUTHORS Qian,S.W., Kondaiah,P., Roberts,A.B. and Sporn,M.B. TITLE cDNA cloning by PCR of rat transforming growth factor-beta 1 JOURNAL Nucleic Acids Res. 18, 3059-3059 (1990) STANDARD full automatic COMMENT SWISS-PROT; P17246; TGF1$RAT. *source: strain=Sprague Dawley; tissue=heart; *source: developmental stage=adult; From EMBL entry RNTGFB1; dated 04-JUN-1990. FEATURES Location/Qualifiers CDS 413..1582 /note="prepro-TGF-beta 1 (AA -23 to 367)" /codon_start=413 CDS 413..481 /note="signal peptide (AA -23 to -1)" /codon_start=413 CDS 482..1582 /note="pro-TGF-beta 1 (AA 1 to 367)" /codon_start=482 CDS 1247..1582 /note="mature TGF-beta 1 (AA 255 to 367)" /codon_start=1247 BASE COUNT 337 a 538 c 403 g 307 t ORIGIN 1 accgcctccc gcaaagactt caccccaaag ctggggcgca ccccttgcac gccaccctcc 61 ccccagcctg cttcttgagt cccccgcatc ccaggaccct ctctcctctg ggaggccgat 121 ctccctcgga cctgctggca atagcttcct atttaagaac accccacttt tgggtcccag 181 agagcgctca tctcgatttt tatcccggtg gcatactgag acactctggt gtcagagcgt 241 caccgcgact cctgctgctt tctccctcaa cctcaaatta ttcaggacta tcacctacct 301 ttccttggga gaccccaccc caccccacaa gccctgcagg ggcggggcct ccgcatccca 361 cctttgcccg gggttcgcgc tctccgaagt tccgtggggc gccgcctccc ccatgccgcc 421 ctcggggctg cggctgctgc cgcttctgct cccactcccg tggcttctag tgctgacgcc 481 cgggaggcca gccgcgggac tctccacctg caagaccatc gacatggagc tggtgaaacg 541 gaagcgcatc gaagccatcc gtggccagat cctgtccaaa ctaaggctcg ccagtccccc 601 gagccagggg gaggtaccgc cgggcccgct gcccgaggcg gtgctcgctt tgtacaacag 661 cacccgcgac cgggtggcag gcgagagcgc tgacccggag cccgagcccg aggcggacta 721 ctacgccaaa gaagtcaccc gcgtgctaat ggtggaccgc aacaacgcaa tctatgacaa 781 aaccaaagac atcacacaca gtatatatat gttcttcaat acgtcagaca ttcgggaagc 841 agtgccagaa cccccattgc tgtcccgtgc agagctgcgc ctgcagagat tcaagtcaac 901 tgtggagcaa cacgtagaac tctaccagaa atatagcaac aattcctggc gttaccttgg 961 taaccggctg ctgaccccca ctgatacgcc tgagtggctg tcttttgacg tcactggagt 1021 tgtccggcag tggctgaacc aaggagacgg aatacagggc tttcgcttca gtgctcactg 1081 ctcttgtgac agcaaagata atgtactcca cgtggaaatc aatgggatca gtcccaaacg 1141 tcgaggtgac ctgggcacca tccatgacat gaaccgaccc ttcctgctcc tcatggccac 1201 ccccctggaa agggctcaac acctgcacag ctccaggcac cggagagccc tggataccaa 1261 ctactgcttc agctccacag agaagaactg ctgtgtacgg cagctgtaca ttgactttag 1321 gaaggacctg ggttggaagt ggatccacga gcccaagggc taccatgcca acttctgtct 1381 ggggccctgc ccctacattt ggagcctgga cacacagtac agcaaggtcc ttgccctcta 1441 caaccaacac aacccgggtg cttccgcatc accgtgctgc gtgccgcagg ctttggagcc 1501 actgcccatc gtctactacg tgggtcgcaa gcccaaggtg gagcagttgt ccaacatgat 1561 cgtgcgctcc tgcaagtgca gctga //