GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATTGFB1 1585 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for transforming growth factor-beta 1
ACCESSION X52498
KEYWORDS TGF-beta 1; growth factor; transforming growth factor-beta 1.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 1585)
AUTHORS Su,W.Q.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1585)
AUTHORS Qian,S.W., Kondaiah,P., Roberts,A.B. and Sporn,M.B.
TITLE cDNA cloning by PCR of rat transforming growth factor-beta 1
JOURNAL Nucleic Acids Res. 18, 3059-3059 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17246; TGF1$RAT.
*source: strain=Sprague Dawley; tissue=heart; *source:
developmental stage=adult;
From EMBL entry RNTGFB1; dated 04-JUN-1990.
FEATURES Location/Qualifiers
CDS 413..1582
/note="prepro-TGF-beta 1 (AA -23 to 367)"
/codon_start=413
CDS 413..481
/note="signal peptide (AA -23 to -1)"
/codon_start=413
CDS 482..1582
/note="pro-TGF-beta 1 (AA 1 to 367)"
/codon_start=482
CDS 1247..1582
/note="mature TGF-beta 1 (AA 255 to 367)"
/codon_start=1247
BASE COUNT 337 a 538 c 403 g 307 t
ORIGIN
1 accgcctccc gcaaagactt caccccaaag ctggggcgca ccccttgcac gccaccctcc
61 ccccagcctg cttcttgagt cccccgcatc ccaggaccct ctctcctctg ggaggccgat
121 ctccctcgga cctgctggca atagcttcct atttaagaac accccacttt tgggtcccag
181 agagcgctca tctcgatttt tatcccggtg gcatactgag acactctggt gtcagagcgt
241 caccgcgact cctgctgctt tctccctcaa cctcaaatta ttcaggacta tcacctacct
301 ttccttggga gaccccaccc caccccacaa gccctgcagg ggcggggcct ccgcatccca
361 cctttgcccg gggttcgcgc tctccgaagt tccgtggggc gccgcctccc ccatgccgcc
421 ctcggggctg cggctgctgc cgcttctgct cccactcccg tggcttctag tgctgacgcc
481 cgggaggcca gccgcgggac tctccacctg caagaccatc gacatggagc tggtgaaacg
541 gaagcgcatc gaagccatcc gtggccagat cctgtccaaa ctaaggctcg ccagtccccc
601 gagccagggg gaggtaccgc cgggcccgct gcccgaggcg gtgctcgctt tgtacaacag
661 cacccgcgac cgggtggcag gcgagagcgc tgacccggag cccgagcccg aggcggacta
721 ctacgccaaa gaagtcaccc gcgtgctaat ggtggaccgc aacaacgcaa tctatgacaa
781 aaccaaagac atcacacaca gtatatatat gttcttcaat acgtcagaca ttcgggaagc
841 agtgccagaa cccccattgc tgtcccgtgc agagctgcgc ctgcagagat tcaagtcaac
901 tgtggagcaa cacgtagaac tctaccagaa atatagcaac aattcctggc gttaccttgg
961 taaccggctg ctgaccccca ctgatacgcc tgagtggctg tcttttgacg tcactggagt
1021 tgtccggcag tggctgaacc aaggagacgg aatacagggc tttcgcttca gtgctcactg
1081 ctcttgtgac agcaaagata atgtactcca cgtggaaatc aatgggatca gtcccaaacg
1141 tcgaggtgac ctgggcacca tccatgacat gaaccgaccc ttcctgctcc tcatggccac
1201 ccccctggaa agggctcaac acctgcacag ctccaggcac cggagagccc tggataccaa
1261 ctactgcttc agctccacag agaagaactg ctgtgtacgg cagctgtaca ttgactttag
1321 gaaggacctg ggttggaagt ggatccacga gcccaagggc taccatgcca acttctgtct
1381 ggggccctgc ccctacattt ggagcctgga cacacagtac agcaaggtcc ttgccctcta
1441 caaccaacac aacccgggtg cttccgcatc accgtgctgc gtgccgcagg ctttggagcc
1501 actgcccatc gtctactacg tgggtcgcaa gcccaaggtg gagcagttgt ccaacatgat
1561 cgtgcgctcc tgcaagtgca gctga
//