GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATTM4 17377 bp ds-DNA ROD 28-MAY-1991 DEFINITION Rat TM-4 gene for fibroblast tropomyosin 4 ACCESSION Y00169 KEYWORDS TM-4 gene; actin; microfilament; tropomyosin. SOURCE Rattus norvegicus DNA. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 17377) AUTHORS Lees-Miller,J.P. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 909 to 17100) AUTHORS Lees-Miller,J.P., Yan,A. and Helfman,D.M. TITLE Structure and Complete Nucleotide Sequence of the Gene Encoding Rat Fibroblast Tropomyosin 4 JOURNAL J. Mol. Biol. 213, 399-405 (1990) STANDARD full automatic COMMENT *source: tissue=liver, brain; clone=liver, lambda-[107,108,115, 122]; *source: clone=brain, pOk18; Homologous to equine platelet beta-TM and human TM30pl. No alternative splicing. See also J02780 for cDNA sequence. From EMBL entry RNTM4; dated 07-JAN-1991. FEATURES Location/Qualifiers misc_feature 1113..1437 /note="vestigial exon 2b" misc_feature 1501..1703 /note="promoter region (exon 1b)" CDS 1704..1835 /note="exon 1b (AA 1-44)" /codon_start=1704 CDS 4830..4963 /note="exon 3 (AA 45-89) (4963 is 2nd base in codon)" /codon_start=4830 CDS 8481..8598 /note="exon 4 (AA 90-128) (8481 is 3rd base in codon)" /codon_start=8481 CDS 9605..9675 /note="exon 5 (AA 129-152) (9675 is 2nd base in codon)" /codon_start=9605 CDS 11332..11407 /note="exon 6 (AA 153-177) (11332 is 3rd base in codon)" /codon_start=11332 CDS 11882..11944 /note="exon 7 (AA 178-198)" /codon_start=11882 CDS 12022..12091 /note="exon 8 (AA 199-221) (12091 is 1st base in codon)" /codon_start=12022 misc_feature 12813..12887 /note="vestigial exon 9a" CDS 15498..15577 /note="exon 9d (AA 222-248) (15498 is 2nd base in codon)" /codon_start=15498 BASE COUNT 3975 a 4244 c 4475 g 4683 t ORIGIN 1 aagcttggtc cagcagaagt gggggtgggg ggctgagtac tcctccaggc cacatacagc 61 atcaggggta gcaggagatg cagtagatct gtggagttga ctcaagagcg accctagcag 121 cgagaaggtg tcacatggct gagtggttct cagagagact gatgggatgc ctcaaacggg 181 aaaggggggg ggggtgattc tcagaacaaa cagcactgga ttctgggaaa ggttaaaaga 241 cacgttaatt aaaacggatg catgacaaat gtgcaaaagg tagaggagtg aaaaatctga 301 gctcagaagg gaattggtcc tgagagtgag tctcttctag gacttttcac aaagccaggc 361 acaggagcag gatatgggct caagggtgct ttggtgacac cttcctcagt atcactacca 421 gagcagtggg gagccaagga aggttctcag caggaaatgg acttgcacac tggctgaaag 481 tctctgtcta cgaaactcag ggagtgtcta taggctccac tttgcttaaa cagagattgc 541 ttgagagctg cattcgaaaa atgagaatgc aaactccaat ttgtagtgtt gcaaactaaa 601 gttctgactt cctcatcaga gtggggactc ttggtgagtc caagaataac cagtcccggg 661 ttaggggatt tagctcagtg gtagagcgct tgcctagcaa gctcaaggct ccgaaaaaaa 721 gaaaaaagaa aaaaaaaaaa aaacaaaaac cagtccctag gtcaagagaa gaataaaatc 781 cctctgtatt cagtaatgca cacttaccgt tgtgtgtgtg tgtgtgtggg ggggtgtctt 841 ttatatttta tgtgagtggg tgttttgcct gcctgcatgc ctgtgctacg gggtcatgga 901 agcagaggat gttggctccc ctggaacagg agctgggaat caaacttaag tcctctgtac 961 aaggacttgt ctatataaac cttttacttt ctacattaat gtgggggcgc atacatacat 1021 acatacttat ctatatgtac tttttacttt cacaaatctg tgtcctctga acgagacctt 1081 ctctatatag acctttcatt ttctacatta atgtgggggt gcatgtgtga ggttaatgga 1141 ctctgggcat caggcttggc gacaagcacc tttacccgtg gagccatctc accagctcat 1201 ataggctttg tgttcatttg caggacctca aactcccagt ccttctgcct cagcctccca 1261 aagagtgggc aaagagacca ttaggctgac tcgttccctt ctgtgtcccc gattgcaaga 1321 gcagctgatg tacctccaga agaaattgaa atacaaggag gacgaagtgg acaggcactc 1381 cgaggacctg aaagacatga agaagctaga gcaggcggag aaaaaaacgc ctcccaggta 1441 agtgcgcgac cgctgggcca ggcggggcgg gctgctccgg aggacgagga gcctgcaggg 1501 caaaggcggc cagccatgcc tacgtcagcc accccctgac cccccgcccg gtgctgacgt 1561 cgcggccggc cggggtgacc tcatcggccc gacagcaggg ccggggggcg gggagaggcg 1621 ggggcggccc cggcgtggcc aaggctcgcg ggcccgggcg cagccgccca gctgtcgcct 1681 gagcccagtg gagcgagtga gctatggccg gcctcaactc actggaggcg gtgaagcgca 1741 agatccaggc cctgcagcag caggcggacg acgcagagga ccgtgcgcag ggcctgcagc 1801 gcgagctgga tggcgagcgc gaacggcgcg agaaagtgag agactgggac ccgcgacccc 1861 ccgcccgatc ccagctttcg tcccgcgcgc tccctagcct gcgccgcgtt cccttgcgcc 1921 ctcttttctt cccagctccg cgcgcttcca gcttcccctc cttccgtcct ccgccttggt 1981 catccacatc cgtggacccg gagccccgta cgctggtggg gcaggaactg gggagttgcg 2041 ggaaacggtt ctgcgcgggg ctctccagag cggtggggca gatgccgcgc tcccattgtc 2101 tgcggctgga ccaaggtggg ggcgggggca gcgcgcgctc gctccttcgc gcccgaactt 2161 tcccggcgtg tccctagggt gcggccgcga cgtgtcgctg agggcggggt gggggtagga 2221 gaattcggac gctggcctgc aggatacgca ccaccaccac caccctgtgt ccccaagccc 2281 cagggaatac ccactagggg gcctgtccac cgcagatact agagcgccca ctgttatgcg 2341 ccttccctga gagtccaggg acccgggtgc aggaatagtt tggaaagagg aacgggcctc 2401 cgcgcctcct cttcatcctt gggtcaagcc cggggccaga gacggatctg ggttctaacc 2461 ctagctctgg cacctacaaa gcattcgatt cgtgtctccc aagagtccgc tagaggtggg 2521 tgggaagaca aaactacgga gaggcattcc acacggttcc ggggtacaga gagcacctag 2581 ctggagtagt agagcggcat ttgctagcga aggagactca cagccaaggg aggggtgttc 2641 tgtgatcgcc caggttccct gaagcctgag tgtgggaact cagggcgggg accctagaaa 2701 ctgaaaggcc aggtggagtt ggcagcacag gcaccgcctg gactcctccc aagactgcct 2761 gggcgacagc ccggtctggg tggaagcctt gaatccctca agtacggctc cggctggagg 2821 aagcctcaga accaggcgga agctctgcac agtagctgtt ctggcttctc aaatgcccgt 2881 cccaccctag acatctccaa aatggcttcg agactccgcc aagcgaggaa tttggcggcc 2941 ggggcggggg tgggaggtgg cgcgcgggtg gggggttgta aaactttggg gcttctttaa 3001 aagttcgtgt gggagagcat gcttcttttg gttgtagaaa gacacctcag gttgattctg 3061 ggccagaagc acccagatca gaagtggggt ggggggctgt atggccgact tctgggcctg 3121 tatcccaaca gctggtttca tttagatttt tgtgtgatta accgacgtct tcctgttgct 3181 tggccacaag tagctcgcaa gcctctttta ccttataagg gaaacccttt gtagcccgtg 3241 gaaggctttg attgcaggaa ggggcggagc tcaagatgac tgtgtgtgtg tgtgtgtgtg 3301 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtc ttgtgtgtgc ttctgttcat 3361 gcatagttgt ggacgacagc tctttcgatt ttttaaacag ttgaaaatat gccaagattc 3421 aaagtgtgcc tcttcagtct taagttcttt tccttttctc ggagccgact catgaatgag 3481 gaaactcagt gtgactgtgg aagtgattac tacattgggt gtggccttga gccctgcagc 3541 ccaggctacg ggagaggctg cgctgtcact gaatggtgga atgcttgctt gagtaatcac 3601 aacaccctga gggtcccttc tccaggactg ggtgagctgg atgaggtagt acattcctac 3661 acttgagaga ggttgagaca ggggaatcag aagttagggt tagacttggt agttgaaggc 3721 caacctgggc ttcatgaaac ctataacctc aaaaaaaaac gacccaaagc tccccatcta 3781 ctgcagatgg gacttcagga tggggtacat ttttttagaa aatggcaaaa gttaacagta 3841 aaggtgcttg ccactaaggc tggtgacctg agttcagtcc cgaagaccca cattgtggga 3901 ggagacagac ccaagacaca cagcacgtgt tggtgttagg ggaggatgga cacagatcac 3961 aaacttgggg cgggggtcct ctgtatatta acaggcaccc tggtcttgtt cttttacttc 4021 ccctgctgta taaactgagg cagagagggg ccactgggtt ttatagctgc cccccatata 4081 gtggttatcc ctgaaaggaa gctggcagcc tagtttctcc tcatgaagct cacgaaccca 4141 cacattttaa aatgtgcgtg ctgggaatcc aacctcaggt ccttatgctg ggcagcaagt 4201 gcttttacca ctaagcttac tccccagctc cccctctttc tggtattttg acagagatct 4261 tactatataa tagttcaggc tggcctggaa ctctttgtcc tttgacttca atttcctgga 4321 gctgggatca taggtgtgtc accatgccct gctaattagg tctccatgtg accaactttc 4381 catgatcctt cttaagggtg gccacccctc ggtgacaggt cactaagtca ctaaacagaa 4441 ccactgcact gatgggaacc cccttgtccc catctgtaag gtgggtgaga cttgaagata 4501 aaacagtatc agggccagca agttttctta gtcattcagg tgtgtgttcc ccagagtgac 4561 tgggcactgg gcctcggctt gcgtcagcac ccagggagcc tgaggcccca ggatccctga 4621 gtccaggagt tggataccag tctggccaat gcacgaggcc ctgtgtcaca gatcaataat 4681 tttaaaaatc caatgcaaat gagtatgagt tcccttgagc ctgggtccct gggtgggttg 4741 tggctggatc tcagggttac tggggggtgg ggaggaggct gcttgccagc ttgcctcttc 4801 ttaatctggg tgtgtatcta actttccagg ctgaaggaga tgcggccgct ctcaaccgtc 4861 gcatccagct ggtggaggaa gagctggacc gggctcagga gcgactggcc acagccctgc 4921 agaagctgga ggaggcagag aaggctgctg acgagagtga gaggtaggat gcttctgcct 4981 gtggaagact tgggggcgga gccagatgtg gtggagcata cctgtggggt tccgtgctga 5041 ggccagcctg ggcgacataa agcctttcct gactttaaag agatgtgtgt gagggctaat 5101 ggctcagtat ttaagtgctg cttaactctc caccacccac ttgaaaagcc agtgtggtta 5161 cacaggagca ctcgggtttg ctgactgcca gcctacctcc aggttcagtg agagatcctg 5221 tctcaagggg gtgagacaga aagtgacaga gctggacact tgacatcctt ctctggactc 5281 catatgcaca cacagatgca cgtagacatg tatgatgggg aaatattctg taatcgtact 5341 aatgaccttg taatggtgct aatgaccttg gcgctgaagg gattggaaga cctgtttgtt 5401 tttaatccag tccccttttc tgttttattt tgtttgaggc aggatctact atgtaatgct 5461 ggggtgacgg atgcttcacc atgggccctg cttggttttc tttatgagag cctagaagga 5521 cactttgcag cagatagaga aaaacagaga tgtgcaggcc tgggactagg gcctcggggt 5581 gtggttgctt tctggggaag ccccggcgcc tctcttgccc actctacagg caatcaagtt 5641 tctagatgac gtgaagagaa gaggaagtaa agatagactg ggcaggcatg gcagtgtaga 5701 cagactttta tccaaggacc agggacacag aggcagggtg acctctgcca tgtccctaca 5761 tggcagttct cattgctgtg gcaagctcta agcttttggg tgcccgctgt attttgggga 5821 cagcgcatgc ataaccagcc atcgctgtgc ctgcagctga ctgtgctgct ctggtgacat 5881 tgtgcagcgt ttgggcttcc atggggagct ctatccaact gtccccagga atgagtggct 5941 ctggcatgtc ttggcttggg gggctgaggg aaaactgtgt ggctgcagaa gctccagtca 6001 cagataatgt ggccagccca gtgctgaggg tttcccaggg aaggctcctc ccaaaaaact 6061 ggtttcaaat tgtgctgcta tgactctaaa ccaggcacta gacagcaact agggactggg 6121 atgtcgctcg acagcaaata cctgcatagc atacatatat acatatatgt attgtgcatg 6181 tgtgtgtgtg tgtatgcaat atatgtatat atatatgtgt gtgtatatat gtatatgtat 6241 gtatgtatgt atgtatatac atacatgagg ttactcagta ggtaagggca tttattgcca 6301 cctgtgacag cccgagttca gttagtgcct gagacccaca ctggagaagg agaggtccag 6361 cccctctagg catcttccac cctctacaca gtgtgctggg gtacatgcat tagtgcacaa 6421 ataaataaat gtaaaattat aattaataaa ccaggtgttt tgtcatattc cacactttta 6481 ataatgtgtg tcaccaagcc ttgtgcctag ttcctatctt tgtatcttgg gggtactgtg 6541 cagggcatca cttgacccac agccatctct ctggtgccca ttaccttgtc tgttccgatc 6601 catatatctc tgccagagca ggctttgctc tgaggctgct aagctgttct ggctgcctga 6661 ggacatcctt ctgacctgga tgaacatagg tgtccttctc tgacatgctc gggacgaaat 6721 acttaggagt ctgggtatct ccagattcgg ggatatttgc ataggtataa tgatctatct 6781 taaaggtggg atcagagtct aaacaaggag ttcatatgca tcctatatcc cttgtgtacg 6841 gggtgtgagg gacatttcat gtgtttctag acctcctttg aacagcggcc tgccacacaa 6901 ggaattctct gtctgtcctg ggactgtgct cacaggttca ggttgtgggt aggccttagt 6961 ggtataactt acttcagact cacactgcac tgggtatcat aaaggttgtt ttgaaagtca 7021 ggcatggtgg tgcaggcctt tcactctagt aataaagcca aaagatgaaa ccctacttca 7081 ttttgtagca ctttgtgctg ctcaggctgt gcctgccttt cctgtagcct ttgcactcca 7141 ggttgtctgt tttgtttcca ttcggttctg gctctagaag cttccagtaa ttcccctttc 7201 cccccagcat aaacatcccg cccatcctgc ccatgtgttc tttcacccct gtgtggtgtt 7261 ttggctcgtt ggtttggaga ggtgtctttt ttctttgttt ttgtttttta atacaaattc 7321 tcactttata actcttgagg gccgggacta aaggtgggtt caccacacag tgcagccccg 7381 acattattgt ttcctgtctt gttgttctta gtattgagac aagatcctgt tatatagctc 7441 gggcttgcct ggtctcaaag gcctgtctca gtctccccag tgctgggatg acagcattcg 7501 cctgccaggc tcctccagtt ccctcctaac ctcagctgag cctctgctct ccctggctcc 7561 tacaccagtt cctcagcttt cctgtaggtg tggctgcgca ttccacactg actcgactct 7621 ctgatcctca ggcttgtctt cctgtgaggg agacaaaaca gggggagcac cctcagaggc 7681 cagccctgct ctgctactta gcagctctgt aaccttaatc tttctctgcc tcggtttctt 7741 tatttgtaaa ctggggagag tagacccaca gagtagtgtg attgtaaaac gtggcgcatt 7801 tgctagtgtc tggaggtcca tgggtcatgg tggggatgca cgcctgtcaa tctagtgctc 7861 ctgaatgctg agcgaggtgt agtagcctgg gctaagtagc aaagtcctgt cttctaagac 7921 ctaaaaaacg ggttgtgggg gtgggtagga gtgaagctca gttgataaga atgcttgcct 7981 ggcatccaca aagctgggtt caatgctcaa taccacacaa gtctatcact ccagcactga 8041 gggggaagag gcaggaggat caggagttca ctgcagagtg agtttgagac cagtctcaaa 8101 aagaccctat gtggctgggg agattgctct ctgggttaag ttcttgctgc aggagcctga 8161 gttagtattc ctgccgactt cgcataaaaa gctatgcatg gcagggggcc tgcagtcccg 8221 gtgctggaga ggctgaaacc aaagggtccc tggggttcca tgaccagccg gtctacggtc 8281 tacggggaac agcaggcttc aggttcaatg agagacctgt caaagatacc acaggctgga 8341 gcggaggctc tgaagttcgt ccagacggct cctcaatgaa atgaatacag aagttgacca 8401 taggcttttg tccttccctg ggtgctgggt gggcgcattt gaggaccttg ccgtgatacc 8461 ccaccctacc ccacttgcag aggcatgaag gtgatagaga accgagccat gaaagacgag 8521 gagaagatgg agatccagga gatgcagctc aaagaagcca agcacatcgc tgaggaggct 8581 gaccggaagt atgaggaggt gagttggcct atgggatagc cgcaggaagt gtgaggaaat 8641 ggtgctgccg ataggagccc atcggaagcc cacactcaag acgattacct ctgtgggaac 8701 atctgtgttt ccagacccag ccacttggct gggaaactgt cttgatgggt accaaacaaa 8761 agtacagtgg tcacttgtcc gagctgctgg agaccaagcg atcagctcat tccgcttgtc 8821 ccgtaagctg gacgcagacc agctgggata agctgagggt cacgattgcc aggctgactc 8881 tgttgtcctt tttttttttt ttttaaatct tcatggacat agaatctcca ctagctcagg 8941 ctggcctaga atttctgttg cccaggctag ccatgatctc ttgactgtcc actgcctcag 9001 ctttccaaac gctaggatta taggtgtgaa ccactatgcc tgactgtctt gtttttggtt 9061 ttccaatata tatttgtttt ggtttttttt ctgagaaagg ttctactgta atccaggctg 9121 tcctccctgt gtaggaaatt atgcaaggat ggccttgaac ccctgactct tgcctccatc 9181 tccaaagtgc tgggattaca gccatgaaca agctggctga attttgtttt tgaagaaagg 9241 gtctgaggta tctcagggtg gcttcatgat cccttttata cagcccgggg taacctttaa 9301 ttcctaattc tcctgcctct gcctcccaag tgctggaatt agaggtcacc gtgcctagtt 9361 ttgttttggt tttgagaccg ggcctcccaa acagaaggac atgtgtcccc accacaacgg 9421 gctcttgtac ttcttccctc tgtgcccagg tggctcagct cgaccttttc ctcccctgcc 9481 tcactgtggg acctgggatg ttccatctct tgcggactcc ggagctcttg gatttggagg 9541 gaccagcgtc tgtagggatg gatggtagtg ggcatgggtc tcagttggtt cttctgactt 9601 tcaggttgct cgtaagttgg tcatcctgga gggtgagctg gagagagcag aggagcgggc 9661 ggaggtgtct gaactgtaag tggcagaacg ggcctgagct gctcatctgg ctctaggcag 9721 aggacgggta gtgggctgtg ctggctggga actgcttgtg gctggggcct ctgaggctca 9781 agagtttcag cattcagagt tcagggctca cccacccttt ggtcattggc tgacagaaca 9841 gctgctgctg ctgattctta ctaacaaggg aagctttcct gcatcgtttt cccaccaaga 9901 tactgtgcag ttgagacccc aggacagcat agaggcccca agtttccttc tcccagcaaa 9961 gcctactgct gggccttcct tccttccttc tttctttcct ttctttcttt ctttctttct 10021 ttctttgttg ttgttttgtt ttgtttcttt gttttgcttt ttgtttcttt gagacagggt 10081 ctcatggcct ggaatgcctg gtcttcttgt ctctgactca tgcactacca cactgagttt 10141 ttttaatttt tgtttttccc aattttattc atagatttat aaacacacac acatcatacc 10201 ataattacaa cacaccctct tttaacaacc tcccaccaac ccccttttcc tcacctccta 10261 agtttgattt cttgtgagac cctctgcagt gtatctatga ttagcatgag cacgaatagg 10321 ggttatttac cgagcaaggc gacttgctga gaagttatac cagtgagaaa tgtgtctcct 10381 cctcccccag agaccattaa ctgctgatag ctacctgggg agggtagccc gcctgagccc 10441 atccctcctc cgtgatggaa tgttgacagg ccccatcccc tgcaggtctt gtgtaggcag 10501 tcactagccc tgtcccgtgc agaagatggc gtttcacagc cctgctgccc acttgcaagc 10561 gcccatgttc cttccaccgc ctcacatttt ctctactgtt ccttgtcggc tgttttgaaa 10621 attttttttt ttcttttttc tttttttcgg agctggggac cgaacccagg gccttgcgct 10681 tgttaggcaa gcactgtttt gaaattttta agacagagtt tttctgtata gccaagctgg 10741 cctggaactt gggatcctcc ttcctgcctc cactttgcac atcaagccag gccatttggt 10801 cctcacagaa tgctgtccgt aggtggcaga tattccacaa gtatttcagg gcgtggcttc 10861 tgatattgct attggtacct gacacattcc ggtggagaca actcagctag aatgtcacag 10921 gtcccaacag acaaaacact cctcctcctt ggccttggac caaggattca gctccacaga 10981 gagcccggaa ggctgggagc accctggttt cacagatgca ttctaggctt gcttcctgga 11041 gtgtcctgtg aactctgaat gccacttccc acctcccacc tcccaccatt gtctatttgc 11101 acaccttcct gagaaaaccc agccagtcac agatttcaca agtccctgtt gcctcatccc 11161 tggcagatgc ccaggttgct ttgcaaaccc tccaaatgcc ctcctgccct gattctgcct 11221 gtgccctgca ggagagggta ggataagctc ccagccgtgg gggttggggg gggtggactt 11281 gctggaaggg aattgcctcc atgaccgcaa atcttttctg ctttggtgca gaaagagtag 11341 cgacctggaa gaggagctca agaacgtaac taacaatctg aaatcactgg aggctgcttc 11401 tgaaaaggtg ggatgcaggg aaacttagta cattttgttc tgtccaggtg acctggcgtg 11461 tcccagggta ttggtgtgca ggcctttgtc aatgggaata gtactgaggc tgagtctctc 11521 acctgaagct catctcgtct agttagccag cttattccat caccacagag ggcgccacgc 11581 catccagctt ttatgcggat gctggggtcc tcgctgccag gcaaatgctt cactccctga 11641 accatctccc cagttccttc ctttcctgaa gtatttattt catgtgtgta agtgcatgta 11701 tgtctgcact gcagggcagg gtgtcagatc ccctggcacc gaacttacaa atggttgtga 11761 gcctctatgt gggtactggg tcctgaaccc cagccctccg taaaagcaac aagagccctt 11821 aacctatctc tagcctcttt ccctctttta agaaccgcct tttgggcttt ctttcctata 11881 gtactctgaa aaggaggata aatatgaaga agaaatcaag cttctgtctg acaaactgaa 11941 agaggtgagc gaccgcaccc agctgcaccc acattttcgg gagctaatct aaaacagggt 12001 agtgactctt cccttcccta ggctgagacc cgagctgagt ttgcggaaag gacagtttct 12061 aaactggaga agacaatcga tgacctggaa ggtaggaatc tccattttcc taagtgacat 12121 gaaagttgag tgaggaggtc tgtggaggga cagagctgtg ctttgtttcc agagtgaggt 12181 cttcagaatt ctcacagaga tgccttgcat attttaaatg cctccagttc ttgctggcct 12241 ctctcccaga ggcagggctt atcttagtgt gaggaaagag aaaaaaggag gctgcaggac 12301 ctcagttccc cagggaacac aactcagcat ttcctgaagt gactgtgtta ctcttcatga 12361 tagagcatgg aaattccaga cacttagggc tgggatcctc caggctgtct catccaggaa 12421 gggagactca ttgtttacat ctttgtccat ataagggaaa atgctccatt ccgaagatga 12481 cctatggcag ggtgattaag ctctcagaag ccatcttggc cccggggaga tggcagtggg 12541 gttatttatc ttgagacggg tcttaagagt gtgaaccagg ccaggcttgc ctctgcctcc 12601 catatgctgg gattaaaagt atgtgccacc acgcccatct ccccattatt tcaagggctc 12661 atctaggcta ctcctgttca gaagctcaga cctgtttgac gtggcactca actttgtctt 12721 ggttcacact gtgtcctcac tactctcgtt tgtctattct caaccctcca tcctatttct 12781 tcaacctctt tcctggggac accaccctgt agacggagtg cccaaaagct ccggtaaata 12841 gctatcagca aggatgtgaa ccatttctca gtgacacctc tctctgaggg cagtgggcgt 12901 caccttggat gctagccatc tccaggtgaa ctggctctgg tgcctaggag ccccagggaa 12961 cccaccttct ggcctggaaa ggggtgggca gttggctctc tgttcctcac agattaaact 13021 ctctttacca aaagaaaact gaggcccact ggtccttttc tgaaaataag gagacaatct 13081 agcatggttc ctcaaacaca acactagctc accaggatgg cagtgcagtc attgtttctt 13141 tttttttttt ttttcttttt tttcggagct ggggaccgaa cccagggcct tgggtttgct 13201 aggcaagcgc tctaccactg agctaaatcc ccaaccccca gtcattgttt cttaatggag 13261 agtgtctgaa attgagtcag cccttgattg gggtccaggc tatgaattcc agtggttgct 13321 tgcactctta tgtgacattt accctaaccc attttgtaag ctgggcagtg gttgtacatg 13381 cctttaatgc caagttggga agcaggggca ggcggatctg agttcaagaa cagcctggtc 13441 tacagagggc aatgccatgc ggaaacactg gggatgagtg ggtgggcatt ttttaaaccc 13501 taccccccat acaccttgct ttgcataagc cctgggacag atcactggcc ttgctcaaac 13561 tttcattgtt tgctcagtat ttccctgaga aatttccaga cacgaatagc ctccaccctt 13621 tgaaatatcc cttcctatct gtctaataat tctactggag ccctacaaga gttcagtccc 13681 ttcttgttgt ctaactgagc tgtgttgagg gtctcaagga cagggagaac tttgggggtt 13741 ggggtgaggc cctttcatct cacttaatta acaaaacttg ctagagaggc caggccagac 13801 ctgggttgca gctcacctcc actactggaa ctgtgcaaca ctgagcatgc cacttagctt 13861 ttctgtaaaa caaaggtgca gtctgggtca ccagagagtt gcctaagaac atggacagct 13921 ggctcacaag agcatccagg tagtaagtct tcacacagct aggtcacagt agtttgtacc 13981 atgaaggctc ctattgctgt agagactgcc gtcttctgca gtctaagctg tttttctttc 14041 tgaaaatttc caggttgatc ttatcacagt ttaggaagcc gtttgctttc ttccagaact 14101 ttaatgaccc ctgtcacgca cgtaaaccag ttttccttca tgcttagtca tgcagagctc 14161 cccgtggctt tttaaaatta ttgtatttat ttacctactt ggtggtgtag aacacacaca 14221 tgccaccgtg cacacatgtg gggacagatg taggacaact caaagggatc aagtctctcc 14281 ttccaccatg tgggtcctgg ggatggaact caggtcttca ggctcttgac ctgatgggcc 14341 atctcacaaa ctgccctttt attttcctct taatcaacac agttatggaa tagttttcct 14401 gctgtcctag gttgcagtct tgtgttattt acctgggatt tgcctgggtt gccaggggca 14461 ccctgagagt aaacactgta tgcctggaat tacagtagct gccccaggta ctccaaaggg 14521 aaacgggttg taggatttac actttcctaa cagatgcact aagccgtctg tatctgggag 14581 caaagcacag cacctcctga attctgaagc atgtctcagt tctcataagg catctgtcac 14641 tcgcacacac tggtggtgct ctccccacct catagagggg cagacataag acctagaaag 14701 gttaaatgac tccagtgatg caccttaggg cttcagtcct agtgctctct ctggctcgtg 14761 gacggctgaa tttatttggg aaggaaaaca cagcacagta agttgagttt taccaaggca 14821 ggaaagttta gtttgtatat tgcattttat gcgacatttg agatgttaaa attttatttg 14881 tagtttgctt gttggcgagg tgcacagtgc catggttcat gtgtggaggt cagaaactgg 14941 ttgtaggagt ctgttctctt cccactacgt gaatcccagg aataaaactg attatcagtc 15001 ctggcagcaa gtgccttttc ttgatgagaa gccagatccg gtatttttct ttgggtttgg 15061 ggtggtattg tcacatacag cccaggttgg cctcgaattg actgtagccc agggcggcct 15121 ctgcctcctg atcctcctgc ctccttccag gctgggttgt ctagtatgca tcacaaagcc 15181 aggctttttc tggacacttg ttttgttttt gtttttgaga catgatctgg tgagatcata 15241 gctctggcta gcctggaact tgctgggtag accaggctgg tcgcctgcct cctgagtgct 15301 gggattcaga taatgcacca gcactcccag cctaatgtcc catactgtct tgtttgctct 15361 ttgatcccta ttactctgtg gtattctgtg agattcttag ctgtgtcttt cactgtcaca 15421 gcttgagctg accagtttcc cttcccttaa caaagatgct tattaattca tttttcctct 15481 gtcttaatct ttaccagaaa aacttgccca ggccaaagaa gagaacgtgg gcttgcatca 15541 gacactggac cagacactaa acgaacttaa ctgtatataa accaaaccag aagagtcctg 15601 tcttgacacc aactccactc cagagagtgc accctgtcct cctctcttat aagaagttcc 15661 gcttactacc atgtctccac cttgctggaa aggccaagca gaaaatgaat tcatgaccaa 15721 acattctgtg ttagacaagc tttgagcacc agttaagttt aatccttcct tttccattca 15781 aatggcacca gcttctttgg ctattcttat tcttaaattg catttattcc taaaatgggc 15841 agggaatttc acactgcgta tagctgctta aggctgaggg catttggttc tcgggaatta 15901 gtcagcccca caccttgaaa cacaggctca agtatctaat cgtgactggt cgctgctggg 15961 gaagtttgtg aggctagggg ttgttgcaag aaaaatgtag aaattttcca cccagagcaa 16021 aaattaaaaa ccgtctatgg gaagtcataa agcacaacta gattggcccg atcttactga 16081 gtctgttcca cactccgccg tggagaacag atttatttac ttcagctttc caggtgagaa 16141 tgctggggtg atcactgctg cccatgtgcc ttccgatcga gctttaattg ctgttccatg 16201 tacacactcc cttcactcca gaattgttct ctgaggagca agtgtcttat tcaggacttc 16261 tctgctgtgg tctaaccata cgctcagcag ggaatatggc agagtccaac ccttttcaga 16321 tcagtcctgt ctggatcaag actgctagca aagccaggta ccagcgctac acagcgagac 16381 tctgtctcaa ataatataaa ggttgccagc catcagaaca ttgatgccaa gggttaggca 16441 acaaagggtc tctccagccg caaagtagtg atagaaaaag aaattggctt aacttcatct 16501 ccattgttca gggaacaaga aatgggagct tgagtttgct gagacttgaa ttcctttggg 16561 aatgacacta ataaagaccg agaactcctg actgaactgg acgtggagcg ctctagaggc 16621 tgcacatatt ttttggcttt gtagttttgc tttttcagtt aacatctcac tgaaacattc 16681 cacattcccc agcagtgtgg ggccacctcg agtttacagt gctgacggag agtcacctgc 16741 ttctagctta tctgaaccct gcccctcact cctatttatt aagcatcaca ctaccaggga 16801 gatgaacttt tagcaaactg tgcaattgat aaaatctact ctgttcttta gattcttgcg 16861 attgtatcat acgtaatggt atcacttttt ctacattttg gtcaaataaa tttttgcata 16921 aataatgtgt gtgggtttac tcgtttagtt gacaattttg taggtatata tgatacattc 16981 tggttattat gcatacacat tctcatcttt tttttttaag attcatttat tatatctttg 17041 tggttttttt tttttttttt ggttcttttt ttcggagctg gggaccgaac ccagggcctt 17101 gcgcttccta ggcaagcgct ctaccactga actaaatccc caaccccaat tcatttatta 17161 tatataagta cactgtagct gtcttcagat acaccagaag ggggcatcgg atcccattat 17221 agatggttgt gagccaccat gtgttgctgg gaattgaact caggacctct ggaagagtag 17281 tcaggtgctc ttaaccgctg agccatctct ccagtccaca ttctcatctc tttacccatc 17341 cctgtttatc ctacctccat ccaataacag cctctca //