GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATTROASM 1636 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for smooth muscle alpha-tropomyosin
ACCESSION X02411 J00706
KEYWORDS alpha-tropomyosin; protein binding site; tropomyosin.
SOURCE Rattus norvegicus RNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Garfinkel,L.I., Periasamy,M. and Nadal-Ginard,B.
TITLE Cloning and characterization of cdna sequences corresponding to
myosin light chains 1, 2, and 3, troponin-c, troponin-t,
alpha-tropomyosin, and alpha-actin
JOURNAL J. Biol. Chem. 257, 11078-11086 (1982)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 1636)
AUTHORS Ruiz-Opazo,N., Weinberger,J. and Nadal-Ginard,B.
TITLE Comparison of A-tropomyosin sequences from smooth and striated
muscle
JOURNAL Nature 315, 67-70 (1985)
STANDARD full automatic
COMMENT SWISS-PROT; P06469; TPMS$RAT.
From EMBL entry RNTROASM; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 17..856
/note="smooth muscle alpha-tropomyosin (aa 1-280)"
/codon_start=17
misc_feature 137..244
/note="isotype switch peptide (aa 41-76) pot. troponin I
binding domain"
misc_feature 726..856
/note="isotype switch peptide (aa 258-284) pot. troponin T
binding domain"
misc_feature 1611..1617
/note="polyA signal"
polyA_site 1636..1636
/note="polyA site"
BASE COUNT 483 a 348 c 436 g 358 t 11 others
ORIGIN
1 cctcgccacc gccaccatgg acgccatcaa gaagaagatg cagatgctga agctcgacaa
61 agagaacgcc ttggatcgag cagagcaggc cgaggctgac aagaaggctg cggaagaccg
121 gagcaagcag ctcgagagac atctcagcaa aagagaagct ctgcggcgtc gaggacgagc
181 ggaccggtgc tcaggagtca caaggctcga cggaaccttg ctggctgccg acgagaccgg
241 cgaagctgaa gctgacgtag catctctgaa cagacgcatc cagctggttg aggaggagtt
301 ggatcgggct caggagcggc tggccacagc tctacagaag ctggaggagg ctgagaaggc
361 tgcagatgag agtgagagag gcatgaaagt cattgaaagc cgagcccaaa aagatgaaga
421 aaagatggag attcaggaga tccagctgaa agaggccaag cacattgctg aagatgctga
481 ccgaaagtat gaagaggtgg cccgtaagct ggtcatcatc gagagtgatc tggagcgtgc
541 ggaggagagg gctgagctct cggaaggcaa atgtgcggag cttgaagaag agttgaaaac
601 ggtgacgaac aacttgaagt cactggaggc tcaggctgag aagtactctc agaaagaaga
661 caagtatgaa gaggagatca aggttctctc tgacaagctg aaggaggctg agacccgggc
721 tgagtttgca gagagatcag taaccaaatt ggagaaaagc attgatgact tagaagagaa
781 aggtgcacat gccaaagaag aaaaccttag tatgcaccag atgctggacc agactttact
841 ggagctaaac aacatgtgaa accctcctta gctgcggcca cattctctcg tttccccctg
901 ttgttttatt ttgtctttaa acacatgctt accatgaaac cccttcaatg cttttttttt
961 ttatatatat atatacttta ccactgtcac tgcaacatct gcagagggca gggggtggga
1021 agacacacag aaagtcagag gtacttgtta tttaaatgtg ccatttccag gttgacattg
1081 ccacacttca cagagtttag gcatgcagtt tgcttagcca gtgtaggaag ctcagcaaaa
1141 caaaaggatt aacagcctaa gntgccaagt gggtggggtc atcaggaaga ctgatgttgt
1201 agacaatcag gtgcagattg gtctaattta aacaaagaac cctggtgtcc cccgttcagt
1261 ctaatacatt tagacttctg tccaacacta atttatttnn nnnnnnnntt agactctgca
1321 actaattact tgtcctgagt agcactgcga gagatatggt tccatgtgcc ctgtcctcac
1381 agccaaggat ttgaaagcca cgctgttctg gtaagattcc caattccttc ccagctgaca
1441 tgcttgtggt cccttaacta gtgggaagag ggctcagtct tttcgccccc ccccccccag
1501 attctgccaa tgtcagggta agagatctag gcactacata tgtaatggta gaagaaaagg
1561 gcattttctc gagagttata actatgttaa acagtttatg aatgatatga aataaaatgc
1621 acaggtagga cattta
//