GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATTPH2 3877 bp ss-mRNA ROD 28-MAY-1991
DEFINITION Rat mRNA for tryptophan hydroxylase (EC 1.14.16.4)
ACCESSION X53501
KEYWORDS tryptophan hydroxylase.
SOURCE Rattus rattus RNA.
ORGANISM Rattus rattus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 3877)
AUTHORS Darmon,M.C., Guibert,B., Leviel,V., Ehret,M., Maitre,M. and
Mallet,J.
TITLE Sequence of two mRNAs encoding active rat tryptophan hydroxylase
JOURNAL J. Neurochem. 51, 312-316 (1988)
STANDARD full automatic
REFERENCE 2 (bases 1 to 3877)
AUTHORS Darmon,M.C.
JOURNAL Unpublished (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P09810; TR5H$RAT.
*source: strain=Wistar; clone=TPH-2; library=lambda gt11; *source:
tissue=pineal gland.
From EMBL entry RRTPH2; dated 18-JUN-1990.
FEATURES Location/Qualifiers
CDS 121..1453
/note="tryptophan hydroxylase (AA 1-444)"
/codon_start=121
BASE COUNT 1118 a 899 c 881 g 979 t
ORIGIN
1 gcttctccta taagaggcgg cagctcccgt ccgcaggtga ccctctgaac tccagtggct
61 ttgaggtcct ctttccagtg ccggatcctg cccactgggt catcttcatt cagattcacc
121 atgattgaag acaacaagga gaacaaagac cattcctcag aaagggggag agtgactctc
181 atcttttcct tgaagaatga agttggagga ctcataaaag cgctgaaaat cttccaggag
241 aaccacgtga acctgttaca tattgagtcc cggaaatcga agcgaagaaa ctcagaattt
301 gagatttttg tggactgcga catcaaccga gaacagctga atgacatctt tcccctgcta
361 aagtcccaca ccacggtcct ctctgtggac tcgcccgatc agctccctga aaaggaagat
421 gttatggaga ctgtcccttg gttcccaaag aagatttctg acctggactt ctgcgccaac
481 agagtgctgt tgtacggatc cgaactcgac gcggaccatc ctggcttcaa agacaatgtc
541 taccgtagaa gacgaaagta tttcgcagag ctggctatga actacaaaca tggggacccc
601 attcccaaga ttgaattcac ggaagaggag attaagacct gggggaccat cttccgagag
661 ctgaacaaac tctacccaac ccacgcctgc agggagtacc tcagaaacct tcctctgctc
721 tcaaaatact gtggctatcg ggaagacaac gtcccgcaac tggaagatgt ctccaacttt
781 ttaaaagaac gcacagggtt ttccatccgt cctgtggctg gttacctctc accgagagat
841 ttcctgtcag ggttagcctt tcgagtcttt cactgcactc agtatgtgag acacagttcg
901 gatcctctct ataccccaga gccagacacc tgccacgaac tcttaggcca cgtccctctc
961 ttggctgaac ccagttttgc tcaattctcc caagaaattg gcctggcttc tcttggagct
1021 tcagaggaga cggttcagaa actggcaacg tgctacttct tcactgtgga gtttggactg
1081 tgcaagcaag atgggcagct gagagtcttt ggtgccggcc tgctttcttc catcagtgag
1141 ctcagacatg cactttctgg acatgccaag gttaagccct ttgatcccaa ggttgcctgc
1201 aaacaggaat gtctcatcac aagcttccag gatgtctact ttgtatcgga gagctttgaa
1261 gatgcaaagg agaagatgag agaatttgcc aaaaccgtga agcgcccgtt tggagtgaag
1321 tacaatccgt acacacagag cattcaggtt ctgagagaca gcaagagcat aaccagcgcc
1381 atgaatgagt tgcggcatga cctcgatgtc gtcaatgatg cccttgctag agtcagcagg
1441 tggcccagtg tgtgaaggtt tccagtgcag aaagcctttg agcatcagtc cagagccagg
1501 gccagttctt gcttccccta aagacctcct tggggaggga cagcagctcc cagcttagca
1561 atgtctctca cctctctgta accaatcact cactgtctct gaaaacgcat acctggatgc
1621 tctagtactg cttgtcttct acttctgttt tgatttctgt cacctgctta gggaaatata
1681 attcacatgc cacatgactc acaggatgca catttaaaat attttatttc attaaaatat
1741 aattatatcg ttctccccct tccctctctt ctctccaatc cctccctctc aaattcatgg
1801 cttacttttg atgggtgagt tgcctgacac tggccagagc tggactcatg gtgatgccgt
1861 ttttcccagt cagccattag cagatggtca gtctggatgc tatgatgagt gttttctgta
1921 tctgttacca gcaccacttt gtgacagccc aggcatagtc acacactaga cttcaaggag
1981 acaagctgaa acagaagtgc agatggcttt gctctagagc acagctagta aagagtaagc
2041 tggcttcacg tgcatgtctg acagggacat agaaatcacc agggcacagc caggcatgag
2101 gatgcctatg atagcagtgc ttcctagcac tttattccaa aatgtcacaa ggtgtggggc
2161 acagagggta ggaaacgggg ctgggaatgg agaagggcca aggagagcag tttgtatcag
2221 attgtaactc tgtgagggct gtaaggattg gagcacgtgt ggtgtcagca gtgtagcctt
2281 ggcataagca gttgtataaa cttttcatta ctgtaacaaa gtgtcaggga caatcagctt
2341 ataaagagga aaagtttgtt ttgggtgtta tggtccatta gacgtcgttc ctgtggttta
2401 agccagtggt gaaacaaggc atgatgagag aatgtggcag agcaaacttc ataaaggatg
2461 gaaagagaaa aagtgaaggg tttagagaaa gaagaagaga gagatggaat gagagaggga
2521 gaacacacac atgggtacgc gcacacacac acacacacac acacacacac acacggggtg
2581 agagagagtc agagacagac agaaagatcc tacagtacag tttaagagtt cattaccagg
2641 gtaagagaga gggctctgca gttaagagta ctcgctgctc ttccagagga ccctgctttg
2701 attcccagca cccacactgt ggctcacaac catccgtcac tccagttcca gagggtccaa
2761 tgttttctgg cctccacaga tagcatgcaa gtggtgcaga gatagaaata cagcgacaga
2821 ttcaaacaca gaaaataaac attgaaagac cccacctctg cctttcacat taatagtaaa
2881 attatatacc attgatcatg cttcttttca agcccactag atgtatgttt atgctagatt
2941 tgtaaaagac accttttaag aattcagagg aaactactga aaactgtatt tcatcctgtg
3001 cttctcaagg aagccggtcg agagagtgta ataaagccat ctcagaactt tataaacaca
3061 ttagctgcca ttgagcatgc acacatcagt aagtaaatac gttcgttctg aaatcacgcc
3121 aagtatggac cagctagttc ccagtctgct tgatcaccag gagagcacta taaagaagcc
3181 ctatagataa caaacatggg agagcagtct gctctctctg gttatttccg caagactctg
3241 gtgatgctgg agaatcagtc actggctttt aaaatggttg tgccctgact aaagcacttt
3301 aaaataaaca gtgaaagcca caaccttacc aagtgtaact tcaagataat agaaatagta
3361 ggtgatagac ttgaccttgc cttggatatg gttctgcgat atttggcaga tcagggttcc
3421 aagagcctca gagttttcaa aacacctaag aaccttttaa taattatgca aacaccagga
3481 cagactcaaa ccaaaagcat ggcctgtaat tctttcccag agagagccat tccttgacat
3541 gtagcatgta tgcgtgactt tttgaagaag acacaaatgc taatcttacg aatgcctgca
3601 ttccttaatc tcatgcttgg gcatttagaa ttacataagt agcaagatac agcaaatgca
3661 caggattact gctcatttta aagttccgtt ccaaaccaga gaaagaaaaa aaagcactca
3721 aaacactcaa taacagagac cgtatgttaa tttccaggac gtggatagag ataactgtga
3781 tctgtttcac tctcgtcttc gtgttactgt ggtgtataca tgtataattt aaacgtttgt
3841 tattccactg ggtaataaac tcaaagttca tgatctt
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