GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS HEFL141 3385 bp ds-DNA VRT 28-MAY-1991
DEFINITION Heterodontus fransciscii lambda 141 gene for immunoglobulin light
chain
ACCESSION X15315 X17646
KEYWORDS immunoglobulin; immunoglobulin light chain.
SOURCE Heterodontus francisci DNA.
ORGANISM Heterodontus francisci
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Chondrichthyes;
Elasmobranchii; Euselachii; Neoselachii; Galeomorphii;
Heterodontiformes; Heterodontidae.
REFERENCE 1 (bases 1 to 3385)
AUTHORS Litman,G.W.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 256 to 3385)
AUTHORS Shamblott,M.J. and Litman,G.W.
TITLE Genomic organization and sequences of immunoglobulin light chain
genes in a primitive vertebrate suggest coevolution of
immunoglobulin gene organisation
JOURNAL EMBO J. 8, 3733-3739 (1989)
STANDARD full automatic
COMMENT *source: developmental stage=germ line; tissue=liver; *source:
library=lambda-DASH; See also <X51316>.
From EMBL entry HFL141; dated 30-JUL-1990.
FEATURES Location/Qualifiers
misc_feature 300..307
/note="regulatory octamer"
CDS 442..478
/note="variable region (AA 1-12) (478 is 1st base in
codon)"
/codon_start=442
intron 479..629
/note="intron I"
CDS 630..955
/note="variable region (AA 13-121) (630 is 2nd base in
codon)"
/codon_start=630
conflict 635..635
/note="c is absent in [1]"
CDS 1340..1376
/note="joining region (AA 122-133) (1376 is 1st base in
codon)"
/codon_start=1340
intron 1377..2707
/note="intron II"
CDS 2708..3033
/note="constant region (AA 134-242) (2708 is 2nd base in
codon)"
/codon_start=2708
misc_feature 3366..3371
/note="polyA signal"
BASE COUNT 890 a 807 c 720 g 968 t
ORIGIN
1 gaatttaagg cactggattc tgaagggctt ttgtttttgt ccatctggga taaaatgtgc
61 aatttctaca gttgttcttt taaatctcac actcttgaca tgagaagggg gggttaaaat
121 cagaaattat tgtgaattaa ccctcaactc ggtggaaata aatacatgga aatgtttaat
181 tggggaccaa tagaggctca ataaaaaaaa tctggtctgg tccacccccc cccacccccc
241 acccaccacc cccccccccc caaccccccg ccgcccctgc tcctctcaac cctccctgta
301 tttgcataca ggttcatata atagatactg gtctcacctt gtccggcact gtaactggat
361 ccactttctg gagttacagt aaaaccctgc tcactaattc ttcacgggtt tttttccccc
421 ccggagggaa tggctgcagt aatgtatctc ctggggaccc tgctactcca tttaacaggt
481 gagacactta tgttaacaga acgttactca attattcatt agattaggaa gcaaagggat
541 ttggtagccc agcctgttta tttatcagtg tgtttttttg ctccaataaa ctgaatgtgt
601 ttttctctct cttgtgtttt gtgttgaagg tgtcctggcg gttcctgtcc tcaatcagac
661 cccaatttca gacccagtct ccgccggtga gacctccgag ttaaagtgtg cgatgcagaa
721 cggcaacgtg ggcagttact acatgagctg gtatcgacag agacccgggg aggctccggt
781 gttcgtgtta taccaatcta caagtggtag catctatcga ggcaccggct tcacggaccg
841 ttttaaacct tccagagaca cctccagtaa cagtcacatt ctgaccatcg gcagcttgga
901 accgggagac tccgccgtct attactgtgc tgccaacgat ggctcagcag ctacatacac
961 agtgagacag ggcaatacaa aaactgcacc aacagaacca ctcagaattc caacagctac
1021 tgaaatattc ctgcctgaga ctgtgtgatg agcttcagaa atattcctta tgtaacttgt
1081 ggaaaatctc actggaattc catgggttta tttggatttt ccccaatatt tgggctatta
1141 tctgggtagg taaacactga tattctcaag gtttcctcac tgatatgtga aaatccttct
1201 ccagactctc agcattccgg ccccagtgaa aggcagaatg tgaaagggaa tgtaataaag
1261 gacagattat taatattttc ccctctttct tcccagcctg tgttttaagt gacccgtccc
1321 attaaaacac tgcactgtgt ttaccttcgg acctgggacc gccctgagtt tacggagtaa
1381 gtaattccct catcctatca ttcatattgt ttcaattatt tattcattta ttgttgcaga
1441 atcggatctg ccctgataac ggtgaaaaaa aattgggtca gatttttatt tttctgtcca
1501 ctgattcagt gctgggaatt tggattctgg agggtagaaa aataaacact aaaatagcag
1561 caaaacaatt gcggatgctg gaaatctgaa ataaaaaaaa cagaagatgt tggaaatact
1621 cagcaggtct gggcagcctc tgcggagaga gagggagaaa cggtgaacag tttcgggtct
1681 ctgacctttc ctcagaaccg aggaaaaact ccattggcaa aaaaaaatgc agaatgaaca
1741 ggggagaaag gccattcagc ccctcgagtc tgttcggcca ggtctgcagt gtgcaggtgt
1801 ggacttctcc gtctattcgc tgcactgttg tataaatagc gagcctgccc cgggtgttgc
1861 tggaagattt acaaacagga attttactca cactcaaagg gggtcgagtt tgacactagc
1921 accccctccc ccacctcaaa aaaagactcc caaagttggg aagtggatta tgctgcggca
1981 gggactcgat ggaccgaatg gcctcattct gcgccccccc catcttgtct gttcctaacg
2041 cacccggtcc cactaccccc cagtccccgc ctcccttccc agccccctcc ttccggctgt
2101 cgttcgttca tgtgaagtgt ctaacctact ttctaaatgg aaaccgcccc gaactttatt
2161 acttttaaaa ctcttttttt ttaaataaag aatttttcct agtgaggtga tcaccgaact
2221 ctgagtgtgg atctgggagg ttgagttact cccaatacat actccgagca cctccataag
2281 acctccagta cagcctatcc gaaatgtgaa acttcctcaa tttttaaact tttgatttta
2341 atctgcccct gaattttaaa caattcgata ttgtctgttg tatttaatat tcagttaatt
2401 aatttatctg aatgtctcga atccatgtac aagtccagct ctcaattgac agggagttaa
2461 gattggacta aatatttaat tttaatccaa tcaaagcaaa atcctgcaga tgctggaaat
2521 ctgaaatcga gtgctggaaa cactcaggct attatattat ttactgtctc tacctaagtc
2581 tgaagtcaag ttaaatgttt gttttaaatt atagtatgtg ttactaattc tggatgtgcc
2641 ttttagaaaa aatgattgat actaacagtg agattccttt cttccaccct gtctctcaca
2701 cacacaggta gtgaggatcg gaaaccatca gttctcctgc tccctccttc ctcggaagaa
2761 atagactccg gatgggctac tctgtcctgc ctggtgagcc gctttaagcc gggtttcgtg
2821 cgggttctct ggagagtgga tgataaagag acagacagcg gggtgaccac aggcaccgtg
2881 tccacggaca gtgatcaaag ctacagcctg agcagttacc tgagagtccc cgccactgcc
2941 tggaataagg gctccagcta tacctgcagt gtggaccacg gctctctgag ctcacctctc
3001 ctcaaaacca tcagctccac cgcttgttcc gactgagagg gggcaactgg ggtttagagt
3061 ttgatttatt gctgatgaaa tattattcaa tatgtggaat gttgttgttg ttgttttaca
3121 atgtaatcac tgtagcaaat gtggccaacg atgttgaaac agtcacttca atcgcagttt
3181 aacgatccaa ttttggatcc aattttaact ggggggcgca ggtgggtgac agtgaatatc
3241 aggaccacct atcccgggag tacattccca tttggagctg gatgggttct gctccctctc
3301 tcctttctct cagtagtacc atttgttaga attgaaaagt gtatctctct gtgtgtggct
3361 gttttaataa agatgacatg aattc
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