GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS XELHISH2 14942 bp ds-DNA VRT 28-MAY-1991
DEFINITION Xenopus laevis histone gene cluster Xlh1 with genes H3, H4, H2B,
H2A and H1B
ACCESSION X03017
KEYWORDS histone; histone H1B; histone H2A; histone H2B; histone H3;
histone H4; inverted repeat; tandem repeat.
SOURCE Xenopus laevis DNA.
ORGANISM Xenopus laevis
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Amphibia;
Lissamphibia; Anura; Archeobatrachia; Pipoidea; Pipidae.
REFERENCE 1 (bases 1 to 14942)
AUTHORS Perry,M., Thomsen,G.H. and Roeder,R.G.
TITLE Genomic organization and nucleotide sequence of two distinct
histone gene clusters from Xenopus laevis - Identification of novel
conserved upstream sequence elements
JOURNAL J. Mol. Biol. 185, 479-499 (1985)
STANDARD full automatic
COMMENT SWISS-PROT; P02304; H4$HUMAN. SWISS-PROT; P06893; H1B$XENLA.
SWISS-PROT; P06898; H2A2$XENLA. SWISS-PROT; P06900; H2B2$XENLA.
SWISS-PROT; P16105; H32$BOVIN.
Histone genes contain a highly conserved region consisting of an
inverted repeat (FT: INVREP A-F) required for accurate processing
of the 3'end of the histone mRNA. The large intergenic region
between H2B and H1B contains interrupted direct repeats ranging in
size from 5 to 25 nucleotides (especially between position 6180 -
6380).
From EMBL entry XLHISH1; dated 22-DEC-1988.
FEATURES Location/Qualifiers
CDS 1..228
/note="H3"
/codon_start=1
promoter 1318..1324
/note="CCAAT box homologue sequence (H4)"
promoter 1361..1367
/note="TATAA box (H4)"
misc_RNA 1392..1397
/note="put. CAP site (H4)"
CDS 1422..1730
/note="H4 (aa 1-103)"
/codon_start=1422
CDS complement(2351..2740)
/note="H2A (aa 1-130)"
/codon_start=2740
promoter complement(2812..2817)
/note="TATAA box (H2A)"
promoter complement(2837..2841)
/note="CCAAT box (H2A)"
promoter 3006..3011
/note="CCAAT box (H2B)"
promoter 3053..3058
/note="TATAA box (H2B)"
misc_RNA 3073..3078
/note="put.CAP site (H2B)"
CDS 3120..3497
/note="H2B (aa 1-126)"
/codon_start=3120
promoter 10813..10817
/note="CCAAT box (H1B)"
promoter 10839..10843
/note="TATAA box (H1B)"
misc_RNA 10861..10866
/note="put. CAP site (H1B)"
CDS 10902..11561
/note="H1B (aa 1-330)"
/codon_start=10902
promoter 12644..12648
/note="CCAAT box (H3)"
promoter 12667..12670
/note="TATAA box (H3)"
misc_RNA 12687..12692
/note="put. CAP site (H3)"
CDS 12726..13133
/note="H3 (aa 1-136)"
/codon_start=12726
promoter 14185..14190
/note="CCAAT box homologue sequence (H4)"
promoter 14228..14234
/note="TATAA box (H4)"
misc_RNA 14260..14265
/note="put. CAP site (H4)"
CDS 14290..14598
/note="H4 (aa 1-103)"
/codon_start=14290
BASE COUNT 4220 a 3193 c 3311 g 4218 t
ORIGIN
1 ctgctgattc gcaaattgcc tttccagcgc ctggttcgtg agatcgctca ggatttcaag
61 actgacctgc gtttccagag ctcggccgtc atggctctgc aggaggccag cgaggcttat
121 ctggttggct tgtttgagga caccaatctg tgcgccatcc atgccaagag ggtcaccatc
181 atgcccaagg atatccagtt ggcccgcagg atccgaggcg agagagctta gatacagttg
241 cgacttttct tactaaacaa caggctcttt taagagccac caaatcccaa attaaatgag
301 ttgaacgctc caatatctgt tcattcgggg aagcccgtga gatccttgtg tagaaccgat
361 ctctaacggc aaccgctgtg gtatcctgtt aatgcttttg tttgtttctg caatctcccg
421 gttatataat gtgtagccat ttcaaacttg tacgacatcc cgctcagtta tccacaaaca
481 taagggctaa tacgaacatc tgcgttatat ctaactagct tctagacctg caacttttat
541 ggtgggatct tcgtttttga aatatttaca ttgtaatagt cgtcgacctc agtgctaaac
601 tcccatcagt cccgctgtat aaccggtaga atgtgacatt tctgtacgga catccttccc
661 gtgaatgtaa catatcatat tagcaaccga accaaggagc agaggccggt ctgagcgatg
721 ttgtggtaga ttgatctatg tattatcagc gccatctagt gtcacatcac atgcagatta
781 aaaaaagtgt aaacgtgttt gggcgattgg gcaatcgtac tgattattac acctaaaaat
841 attagattaa ttagaaaaac gaataaagct cgcagatttg tttacagaat taagatcgtc
901 agtgaacgtg aatcatggta caaagattgt aattctgata tcacaaaggt cttcaaatgg
961 gccaatagga ggtcaacaat tttttttaaa gtagccaata ggacagaaat tccttatcga
1021 gtaccactta aaatcattat cttgtaaatt gtaaatactg cttcactaaa tttctaacgg
1081 cactctataa atgaaattaa atcgtgtatt gcctccaaga aacactggaa attcgcagtt
1141 ggttgaggtt cataagaata agttaatgag cgatagagtt agagaataaa aaatagatac
1201 catataattg acacatcgtt gtaaatagta aattacacac tttgcggaag atttctaaat
1261 gtatatttac tgacagaagt ggaaaacaaa taaaatctag aaggaagcgt ttttagcccc
1321 gcccaaatgt ccagttccct atcaggtcga cttttagtgc tatataatgt gtagctatgg
1381 gggtgactag gcagtttgta cggaacgcat cttaactcat catgtctgga cgtggcaaag
1441 gaggaaaggg cttagggaaa ggaggtgcca agcggcacag gaaggtgctg cgggataaca
1501 ttcagggtat cactaaaccc gccatccgcc gcctggcccg gagaggggga gtcaagcgca
1561 tctcaggtct catctacgag gagactcgtg gcgttctcaa ggttttccta gagaatgtta
1621 ttcgagacgc cgtcacctac acagaacacg ccaagaggaa gacagttacc gccatggatg
1681 tggtgtacgc gctcaagcgc cagggccgca ctctctacgg cttcggaggc taaatgttct
1741 actgcccatt aatcttatac tcaaaggctc ttttcagagc cacccaccca ctcatattaa
1801 gaattgtgat attttgaacg aggtatcttc tagattttta tttaatgctt tatgtgccca
1861 agtgttattg tagttgctgc acttcgattg gagcgcactc ttttctagca ccattataac
1921 tttatactgt ggattgtgcg ccctgccttc ctagagtaga ttttgtcgct gggcatctct
1981 cccgatacag ccaatttgtt tagaaacttt cactgcagca gagtagagct ggacacaaac
2041 cgcatggatc tcccattagc ctctttgaaa tgaattgcta tgggctggag ttaaccatgt
2101 accactgtac ttacagggta gaaatgcccg attgattggt tgctctaccc ctgccctaat
2161 ggattgcacg ggggatacat tgttacgggt tatggttgtt tcttctacac cttcgagcct
2221 catacaaaca ccagtcgctc gcaatgagca aatttagtta ctctaaatat gaaagaatat
2281 cagccttttt agcaggtgtg ggtggctctg aaaagagcct ttgtgttcag attgcggaca
2341 gggcagctca cttgctcttt gtggatttag aactctcggt tttcttgggc agcagcacgg
2401 actggatgtt gggcaggact ccaccctgag cgatagtcac ccctccgagc agtttgttca
2461 attcctcatc gttgcacagc gagttgcagg tgcctgggga taatacgggt ctttttgtta
2521 tctcgggcag tcgttcccag gccaattcca ggatctcagc agtcagatac tcgagcactg
2581 cagccaaata gaccggagct ccggctccca cccgttcagc atagttgcct tttctcaaca
2641 gacgatgaac acgaccaact gggaattgca gcccagcacg agatgagcga gtcttggact
2701 tagcacgggt ttttcctcct tgtttgcctc tgccagacat gttaacaaaa ctcttttctc
2761 accgactaga taaattctaa aataatacgc aaagagccgc tgaaccgctt atttatagag
2821 tgtactcggt tcgttgattg ggtgagtttc aatgcagcca atggtagagg tgctttaaca
2881 ggaaccaacc aaaagatcac agggctaatc tttgtgttga atggataata atgcatactt
2941 ccccccctca taaattcgtc agtgagctct ttgaagtagg cgtttcagtc atgtgacaaa
3001 aatggccaat agaaaactca aagacagagc tgcctcgttt gcatgggagg actataaaaa
3061 tgatcagcga tagagtttgg gtacagtgta tagagacaga atagcgagtt ttgttgaaaa
3121 tgcctgaacc agcaaagtcc gcgccagccc cgaagaaggg atccaagaaa gcggtgacta
3181 aaaccccaaa gaaagatggg aagaagcgta gaaagagcag gaaggaaagt tacgccattt
3241 acgtgtacaa ggtgatgaag caagtgcacc ccgacaccgg tatttcctcc aaggccatgg
3301 gtattatgaa ttcctttgtc aacgatatat ttgagcgcat tgcaggggaa gcctcccgcc
3361 tggctcatta taacaaacgc tccaccatca cctcccggga gatccagacc gcggtccgcc
3421 tgctgctgcc tggggaactg gccaaacacg ccgtgtccga gggcaccaag gctgtcacca
3481 aatacaccag cgccaagtaa ctgctccttc ccttgtccta ctcccaacaa cacaaaggct
3541 cttttaagag cccccacatc ttattttagg aagatctgta acttctctga ggcgtgctaa
3601 tgaaaagtaa tattttaggg cttcatattc tatagtgtgt ctgtctcttc tcggacttta
3661 caagaaaatg cttttggcgt tcgtgacatc cctaactttc tataaatact tgagctttaa
3721 cctcgctgtg tgagtccctg gttctacagt gttatctata gacaatatag tacgagatgt
3781 cactcgcgtt ctcagtttcc ttgtttattc tgctcggttc ttttctacaa ctttctcatc
3841 tttctttctt ggcccacgtt ctcactggct ttttctccca taagtcctcg cttgctctgt
3901 ttcctacagt tccccaaaca ctccccacca taggtaacgc tcagctgggg ctctacagta
3961 gcctgatgtg ggtgtctgga gtattggcat tatgggtaat gggggggggg atatattacc
4021 tgcacaaaaa aataaaccca ggtccccaga tatgccaata aaaccactcc agaagatgga
4081 tagattggga gcattgcctc cccccatgct tgcacaagct gaacacccct agtttctctt
4141 taatatttat cacatgaagt aatgttgata ttgataatat agatgaatta tgggagatta
4201 cttgcctttt aaatgaggtt ggatatagga aaagtgaatc acttttagtg gaatctgtct
4261 tgtttttttt tctctttttt tttttttcgt tctttttccc accgctgtta tatatgaggt
4321 gcagtactcc ggtatgtttt agaaatgttt tcatcccaat aacaatatat agatcttcac
4381 ctgctgggcc tacttgtcct gccacccagg ctttgagtac catccccctt ttcaccaggt
4441 gggatccaaa gaggctgagc acatggcttc ttcttttaat gtataggtaa gccttttatt
4501 ttaaaattca ctaaaattac tctaaacagt tcagaagaat aaataaaggt cagcatttgc
4561 tccatgtcac tctttgttcc tatcacactg ctgatataga ctttatatat tatataagat
4621 tccttcccat ggcagacagg gatattaaaa actaaatgta ccctatagaa ctgcacttat
4681 cccagcagca aaactctggt catgatgctc cccccacatg gttcccaatt tcccacttgg
4741 tctctgttga tgtgaaaccc accagcagag gcatctctgc ctttagccct aaccaaacag
4801 ctttccaaaa cgtgcctgtg catctgatca atgttttctg agctattcta ttcagggctt
4861 cagcatccat tacaacaaaa caggggccta aggacagtct gaaatttagg gttcagggaa
4921 aatcctcaga gaggctttag ccaagccttg cagtataagg ctcatattaa ccagtttact
4981 catcatacat atcacctatt atttggcata taaaacgtat acccttgtcc attttagctc
5041 tacactattc ctgaaatcat cagggtcaaa tttgggggga taaataatgc ttgaacaggc
5101 tttaacacta gaaccagctt tggacttacc tctaaacccc accaataaaa tacagtaacc
5161 ccatcatgcc catgatatca ctgtagatta tggattgaga agcattttta ttaatccaag
5221 atacaccagt aaggttagaa tgtggatcac gcaaatcttg acctttagct ttgtataatt
5281 tgcacaagag aaaggccaat aggaaatctg cagccacaca caagaccagc acattctgaa
5341 agccccacac cagtcagatc aggggaagta agggggttag tcttttatat gactgttgga
5401 tttcagtgtg tctctcattt cagatgggtt ttctctgtca ggatgtctcg gaatgagagc
5461 agtcatggca ggtttgttgc atatgatggg tggtagtggt gggacatctt tactttactt
5521 tgtgcccacc tctaaagagg tctgagaaga gggcaacaga cagaaaagac atgataacga
5581 gactgagaaa aaccaagata tttcttatgt tccatagtga ctgggagagg taaaagacca
5641 gacagattga tggactgaca accaatcata tggattgatt tgattccatc atgaaatttt
5701 ttatgttgat gaacaaggaa attgagatgg gtttggtgtt caggggaccc agagaaattc
5761 tttttgccag agtgaggata ttgatggaca taatttcctt ggtgagggac agacataaga
5821 caaatgaggt ttccacgggg ggatcttagc ccctccaccg cctaagacag cttgctgctt
5881 ccccccaatc tcgcctttat gtgctggagg ggtccaggga gtccacaaca tctgcagggg
5941 gcccctggag gcagggctga tcctatcaaa tgtggggccc aattgggacc atgttggcgg
6001 gcccctagac aaagtgttgc tggctactga catttaggaa aataagggca tacaggcaga
6061 aaattgaaag gaaaggggca gacaaggtaa gagagtgaga gggatgaaat aggggcacat
6121 aataggggca cacagggtaa gagagagagg gaggaaatag gagagtggac tgggccaatt
6181 agtttggggc aggctgggcc gattcagctt gggagcaggc ttggttggat tgggggcagg
6241 cagggctatc aaggttggag gaaagctggg cctatgagag ttgggggcag gctagaccta
6301 tggagttggg ggataggctg gcttatcaga gttgggggtg ggctggacct atggatttgg
6361 ggatgggctg gactttcaaa gttgggggca ggccaggcac catcatgtgt tgagggaaat
6421 attatctgtg ctgccctgtg tgcgggccca atcagttgtc caataggcct aagcccctcc
6481 tggaggttcc aggaaacatt ttttgattcc ttttctgcac aatggtattc atccatgcat
6541 tgctggtctt gccctgtcca agagtttcca gagtcagact gtaaatcata ttatgtctcg
6601 ttaaaacccc tgtttgtccc atgcatttat tgttcagctg tacagtgttg cgtgcattag
6661 tagtgccaaa ttattaaaac acacacacat atactgtata tatacaaaca tgtattgttt
6721 tatagaatac aattttccat tagctgagga tgcagtagta gtagagcatt gaacgtgaag
6781 gcatgtaact agcctcgttg ccccacaccc aaacatgcct tcatcggata gccacctggg
6841 ttctgatttt tcggcatctt acaagggctg ggtaaaagtt cattccccag ggttctagac
6901 ctttccacac ggaacctgca tcagttatcc agtcatttat ctaaagtggg atctgtcatt
6961 taaaccggtt tttgttctgt agaatgtgtt tgatctatga ctgtaattca ggaagggcac
7021 tcctgaaaag gtcagctatt accctcttct tttcatgact cgaagtgctt tttgtatttt
7081 tcgagaagag tctgatggag aatattagag aaacgttcaa aagccttttt aagtgatgac
7141 aaattaaaac ccctagacca gacttttttt tggcatgaac aacattcaga tgtagaagga
7201 gttgggagca aaataagcat gaaaaaaggt tcctggggct gccaaataag ggctctgatt
7261 ggctatttgg taaccctatg tggactggta gcctacaaga ggttcttttt ggccagtaca
7321 cctgggtttt atgcaaccaa acttccctcc aaaccattaa ttcaaaaata agcacctact
7381 ttgaggccac tgggaccaac atccaagggg ttcgtgagtg acatgttgct ggttggggat
7441 tacttgctta aactatacaa gattttaaaa taaatttttt aagatcaact acacctaaag
7501 tggagtaact gaccaaaggt atgttttttt taatatgcgg agggtgatta gatgaatttt
7561 ataagatggt agttgctgta cctttttttt taacaaaaag ggggtattta tgcatcctcc
7621 ctgccctgat atctggacat caaggtagtg aatagtgtcg atccctcaac tcaaaagtaa
7681 atgtcaattt taagttttta tcaatattgc agccatataa atgttttttt aatgggatgc
7741 tgttgttata aagagacctg tactcctcca gcccatctgt aaatgaacaa atgcaggagc
7801 aagatatcaa tgtgtccaga cttatactgt gcatacttcc tgtcagctta aaagtgaaag
7861 ttactgttgt gtaatgcttg catgagcctg ctaataaagc actgttatac tctattcatc
7921 ctcgactacc aaaacatact aacgagcgcc atcatctttc ttcggtcttt ttcggcagtt
7981 gttcgcgcat agcctgggag taaaatcccg atcccgcacc actgtgattg cgaagaaagt
8041 catgaaaatt taaaaaaaaa gtctgaaatt tacgtgattt tcagcgcatg catagttgtt
8101 caagaccgga aatttactcc aactgcgcat cggcgaaaat accatcaaga cacgaagatt
8161 accggagaat aagaagatgg ctgccgtgaa ctccgaggcc agaatctgca cggaggggtg
8221 agtaaaaatt aggggcatat ccccgggggg gagggcatgt aggctggggg gagggttttt
8281 tttttattag aagttgaatt ctcatttaag gaggtcacct gtagtgttgg ccaatcaatg
8341 atggaaggtt tgtcaatata aatcacagga ccactgttcc tgatacagga aggaagatgt
8401 gataacattc atcaaaataa tttttgaccc ctatgaaaga gtgtgtctgt gtactggagt
8461 ttttttattt tcatttatta taggtgtaga cataaagttt cttttttttt tttggataaa
8521 tcctttggca tcttcaactg tcccaaacag atttaggtcc aagaagggct gaaggatttt
8581 attgttttac tgtaagctgg agtcagtagg atttgttaac ttatgcattg agcacgaggg
8641 catgtcaaca ccagtcatcc tgatcctagc actgggcatg ggcaatgatt tacagacttg
8701 agagggctaa gagaaggcac attttgacat gtattattct attttttaga ctttttttcc
8761 ccgctgtgca taatgcgcta ttttttggct tcttttgacg tggcttttgg atagttttgg
8821 gctggttttg tgatgacatt ggctcctccc ttttaaagtg catttttgtg ggtttcttaa
8881 attgctatcc ttttattttt aattcttgac cgtttttcca aaattgaagt ttatagttta
8941 atgttcttgt ctctggtgtt ttagtctggc agttctgtga tccagatcag attcttctta
9001 caatttgcta cattcagttg atacatttct taaccgcatc tgtagaatat tagcaactat
9061 tctatcaatt gtaacagctg tctttaatga aactcaggga ttctgctcag gcaggctaaa
9121 gataagaagt gtatcaatta aatgtatcga tttagaacca tttacagggt cataagctga
9181 aaaattaaac tttaaacttc agtattagag aaacagtgac aaatagataa tagaaattga
9241 aaaatgttaa cccttttaac tctcaggatg tctgtaaagt gaaagagggc agccgttctc
9301 tacaaccacc agaggaatac cattccctat ttgaaaaact aacaggtgtt ggttcatttt
9361 tcataactgc tggtttcgga gtgctagtag tgctagagaa agttcctaca tgtattgtgt
9421 gggtgtctat taaatctaga ctaattataa accaccgtta attcagattt catttattct
9481 aatttgttat actagttttt atcaaatgaa ttatattcct attgttttca aaaccactga
9541 actcaatcct gagtttcctg atgtctcttt gtatgttatc acatacattt cagagaacaa
9601 ttggaaataa caaatcaaac cggttataca atttataata gggatgcacc gaatccactt
9661 ttttggattt gcgccgaacc cccaaatcct tcacgataga tttggccgat gcaaaattag
9721 gggcgggaag ggtaaaaacc taatttccat atgcaaatta ggggtgggaa gggtaaaaca
9781 tcttttactt ccttgttttc tgacaaaaag tcacgcattt tccctcctgc ccctaatttg
9841 catatgtaaa tcaggattcg gttctgctgg gcagaaggat tcggccaaat ctgaatcctg
9901 ctgaaaaagg ctagatcctg gctgaatccc gaactgaatc ctaatttatg tcctcaaata
9961 agttggaaac aaaggccgcc aggataattt tagctacatg ttgcacctag tggcttcaca
10021 gcaggcattt aatttttaat accaggcatg aggcaagttt tggttgagta aaaaactaga
10081 tatactgcca aaataagctt cctgtgggct gccagttcac ataggggcta cagtagttaa
10141 tcaaagctca tatttggcaa ctaaagtaac tttttgcatg cttgtgttgc tctccaactt
10201 cgaattacat ttggatgtag ctcagaggta gagctcagag gtagaaatgg ttggggatcc
10261 ctgatctata atgtaaggac taattaaatc cattgcagtg agtgggaccc tcccctgagt
10321 gcctgcactc cagatcccac agcaaagcct cctgcactgt gttacttgaa tgggagtccc
10381 gagcccacac attccccata ttgcctcctc tctcaaccac atctgcccat attgtacccg
10441 gggggctcct ctatctctgg gggggaccgt ggaagagaaa gaatttatgg aacatgatac
10501 aaatgtgata gaaatgagcc catagaaaga accagaatat tttcatggag aatcctgaat
10561 aaactggagc tgttccggcc aatctctgta accagcgacc aaataagccc tttagtgggc
10621 acgggcatat actagggaac aggatcccac acaaactggg cgcatttatc atcagagaga
10681 agagaaaccc cccatttttg agactctgga aacacagacc gatatatgtc ccaaagcttc
10741 caccagcgac aatacatggg cggggtttta catatcaccc aatagcaaat aaagtctaac
10801 tctgagagtt gaccaatcag cgagccggaa aacctgaata taaggacatc tggaagaatc
10861 gagtttagat tttagctcgt gtgagagaat ttggatcaag aatgacagct acaactgaaa
10921 ccgctcctgt cgctcccccg gcagaaccag ccgctgccaa gaagacaaag aagcagcagc
10981 ctaagaaagt agcgggaggc gcaaaagcca agaaaccctc cgggcccagc gcatctgaac
11041 tgatcgttaa agccgtgtcc tcctctaagg agcgcagcgg ggtgtccctg gccgctctca
11101 agaaggctct ggctgccgga ggatacgatg tggacaagaa caacagccgc ctcaagctgg
11161 ctctcaaggc cttggtcact aaggggactc tgacccaagt caaagggagc ggagcctccg
11221 gatccttcaa gctcaacaag aagcaactgg agaccaagga caaggcggcc aagaagaagc
11281 cagcggcgcc caaagccaag aaaaccgcag ccggggcaaa gaaggcgccc aagtccccta
11341 aaaagcccaa gaaggtctcg gcagcagcaa agagccccaa gaaggtgaag aaactggcaa
11401 aggccgccaa aagccccaag aaaccgaagg ctgttaaagc caagaaggtg gccaagagtc
11461 ccgctaaaaa ggccaccaag cccaaaactg ccaagagccc agcaaaggcc aaagtcgcca
11521 aacccaaagc ggctaaagcc aagaagcctg cgcctaagaa gtaatgtgcc cgcaaccccc
11581 gctcatccca ccaaaggctc ttttcagagc caccacttcc tccattaaaa gagccccgat
11641 actgtatcaa tgggttaatt gtctcacagg gggttctttc cggcattcgt tgaaatttgc
11701 catcaaatta tacttttata tatgcaccat ttcatttgta tcacaggcaa ctctgagcaa
11761 atttacagtc ttacactgcc accgtgtggc aaattgcacg taattcacat aagtacttcc
11821 aatgctttgc aaaatgcttt gggtttcctg ctgtgctttt taaagatgac tgtgaaatcc
11881 agctggattt ttttaaaatt aatataggcc gattttttct tgtgtaataa aactacattt
11941 aacaattttt cctttccttt gggattgggt ttaagcaccc tgggaatgtg aatgatccca
12001 gtctcccctc ccccttttta tctctattaa tattggatac aactgtatat gaacggaagg
12061 gacttgtact ggatacattt atatccttct cttgctgtac ccacggctga ttttagacag
12121 ttttaatgac ttcatggaat aaaacctacg tttttatttt aacaattgaa tccatgcgtt
12181 atgattggaa ggtgccaatc aatgttcgtt tattgaggta tgatctattt atgttcaatt
12241 gttttaaact gaaatgttcc cctgcgtgag attaatatgc cttcacggga tggcgcaggc
12301 tacaatacaa tctattatct ataaacggaa tatacgaatg gggcaaatac tgaccgtgcc
12361 ttatagagac tgagattttg gcgggctggc tatggcaggg tttttttttt tcaccggtcc
12421 aaaaggagtt gtgacgttac atgacttcaa gttccttatt agcaaatcaa agcagaatat
12481 ttagagcggg ctcttttaaa tttgaattct agccttcccg ccaaggtata attacgtcac
12541 agaacgactg gttattgatc agcaaatcaa atcaaattcg atttttttag ccttcccccc
12601 aaccaataag attcgagttc agtcaatgac ttaatttagg tatccaatga aaaacgagag
12661 cctgtgtata aataagaggc aggaagcgat ttgcttcata acattttttg ttgcgttaaa
12721 tagctatggc tcgtactaaa cagaccgccc gcaagtccac cggagggaag gctcctcgca
12781 aacagttggc cactaaggca gccaggaaga gcgctccggc cactgggggt gtcaagaagc
12841 cacatcgtta ccgcccaggt actgtcgctc tccgagaaat ccgacgttac cagaaatcca
12901 ctgagctgct gattcgcaag ttgcctttcc agcgcttggt tcgtgagatc gctcaggatt
12961 tcaagactga cctgcgtttc cagagctcgg ccgtcatggc tctgcaggag gccagcgagg
13021 cttatctggt tggcttgttt gaggacacca atctgtgcgc catccatgcc aagagggtca
13081 ccatcatgcc caaggacatc cagttggccc gcaggatccg aggcgagaga gcttagatac
13141 agttgcgact tttcttacta aacacaaagg ctcttttcag agccaccaaa tcccaaatta
13201 aatgagttga acgctccact gtctgatgtt ttttcggggg aacattgggt aaatattgcc
13261 ttaattttcc gctcatttat ccagacacac aaactaatac taatgtattt acattgcaac
13321 agtcgtccac cccagtgcta aactcccatt tgtcccgctg tataatcggt acaatgacat
13381 ttctgtacgc acatccttcc agtgaatgta acggcatgtt agcaaccgaa ccaaggagca
13441 gaggccggtc tgagttatgt tgtgtagatc ttccatatgt attattagcg ccacctagtg
13501 tcatgcggat aaaaaaaaaa aactttgtgg ttttagagat tcgatacggg tggtggttgg
13561 gcacttggtc aatcgtactg attattacac ctaaaaaata tagagtgata aacacggaca
13621 aactaataaa gctcgcagat ttgtttacag agtttaagct cgttagtgac gatgaatcac
13681 ggaacaaaga ttgtgatgtc tgacatcaag ggcttcaaac ggcccaatag gatgtcaaca
13741 atatatttaa gagtagccaa taggacggat tttcataatt cgtgtaccgt agagcaaatt
13801 taaaacttaa aatcattatc ttgtaaattg taaatatgct ccctaatttc tacggcatct
13861 ataaattgaa ttaaaatcgt gtaccgcccc caagtaacac tggaaattcg agttggttga
13921 ggttcataag aatctgttaa tgagcgatat agttagagaa taaaaactag ataccatata
13981 attggcactt cattgattcc ccaaaccttt caatgataca tcatgacaat gtgtttatca
14041 ttggatgaga ttcattattt cggttaaagc ctaaatagca aatgacacac actttgcgga
14101 agattctaaa tatttctaaa tgtatatttg ctgacgggag tggaaaacag aaataaaatc
14161 taactacacg gaagcgttat tagccccgcc aaatttgtcc agttccctat caggtcgact
14221 ttagtgctat ataaggttgt agctatgtga gtgactaggc agtttgtacg gaacgcatca
14281 ctactgatta tgtctggacg cggcaaagga ggaaagggct tagggaaagg aggcgctaag
14341 cggcacagga aggtgttgcg ggataacatc cagggtatca ctaaacccgc catccgccga
14401 ctggcccgga gagggggagt caagcgcatc tcaggtctca tctacgagga gactcgtggc
14461 gttcttaagg ttttcctaga gaatgttatt cgagacgctg tcacctacac agaacacgct
14521 aagaggaaga ctgttaccgc catggatgtg gtgtacgctc tgaagcgcca gggccgcact
14581 ctctacggct tcggaggcta aatcttctac tgcccattaa tcttataccc aaaggctctt
14641 ttcagagcca cccacccact catatcaaga gattgtgata ttttgaatga gagattattt
14701 tctgtgtttt cattaactgc tttatggtga ttgttatatt gtatttgctt cacttctatt
14761 tatggattgg agcgcgctct cttcttgcgc cattataact ttatactgtg gtctggtgga
14821 gtgtgcccgt tgtacagtaa atgtgcgccc tgccttccta gaatagattg tgtcgctggg
14881 catctctcac gatacagcca atttgtttgg agattttcac tgcagcagag tagagggaat
14941 tc
//