GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS XELTGFB2 3500 bp ss-mRNA VRT 28-MAY-1991
DEFINITION Xenopus laevis TGF-beta2 mRNA for transforming growth factor-beta2
ACCESSION X51817
KEYWORDS growth factor; transforming growth factor.
SOURCE Xenopus laevis RNA.
ORGANISM Xenopus laevis
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Amphibia;
Lissamphibia; Anura; Archeobatrachia; Pipoidea; Pipidae.
REFERENCE 1 (bases 1 to 3500)
AUTHORS Rebbert,M.L.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 3500)
AUTHORS Rebbert,M.L., Bhatia-Dey,N. and Dawid,I.B.
TITLE The sequence of TGF-beta 2 from Xenopus laevis.
JOURNAL Nucleic Acids Res. 18, 2185-2185 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17247; TGF2$XENLA.
*source: cell line=XTC cells; library=lambda ZAP;
Data kindly reviewed (16-AUG-1990) by Rebbert .M.L.
From EMBL entry XLTGFB2; dated 16-AUG-1990.
FEATURES Location/Qualifiers
CDS 79..1317
/note="prepro-polypeptide (AA -301 to 112)"
/codon_start=79
CDS 79..135
/note="signal peptide (AA -19 to -1) (by similarity)"
/codon_start=79
CDS 136..1317
/note="pro-TGF-beta2 (AA 1 to 394)"
/codon_start=136
CDS 982..1317
/note="mature TGF-beta2 (AA 282 to 394)"
/codon_start=982
BASE COUNT 1052 a 743 c 739 g 966 t
ORIGIN
1 ccacataggt tctatttaca tttttttttg tatatacttt tcaattttgg gacttgtgga
61 tcattagcaa agaagaaaat gcactactat gtcctgttca ccttcctgac cctggacctg
121 gcccccgtgg ccctcagtct gtccacctgc agtgccctcg acatggatca attcatgcgc
181 aagaggatcg aggccattag ggggcagatc ctgagcaaac tgaaattaaa cagcccccct
241 gaggattacc cggaacccgg agaggtttcc caggatgtca tttctatcta caacagcacc
301 agagaccttc ttcaggagaa ggccaacgag agagctacct cctgtgagag ggagaggagt
361 gaagatgagt attatgccaa agaggtttac aaaattgaca tgctacccta ttacacctct
421 gaaaatgtca ttccaccaag ttataccacc ccatacttcc gaatcgtacg atttgatgtc
481 tcttcaatgg agaaaaatgc ttccaacctg gtgaaggcag aatttagagt gtttcgttta
541 atgaatacaa aggcacgggt atcagaacaa cggatagaat tatatcagat tctaaagtcg
601 aaagatttgg cttcaccaac gcaacgctat attgatagca aagtagtaaa gacaagagca
661 gagggagaat ggctatcctt cgatgtcaca gaggcagtca atgaatggct ccatcacaaa
721 gacagaaatc ttggatttaa gataagtttg cactgtccct gctgcacctt tattccttct
781 aataactaca tcattccaaa caaaagtgaa gaattggaaa ccaggtttgc aggtattgat
841 gatgcctaca tgtatgctgg tggggattcc aagagcaaga ctggccggaa gaagcacaca
901 ggcagaactc cccacctcct gctcatgctt ttgccttcat ataggcttga gtctcagcaa
961 tccagccgaa ggaagaaaag agctctcgat gccgcctact gctttaggaa cgtccaggac
1021 aattgctgtc tacgtccctt atacattgac tttaaaaagg accttggttg gaagtggata
1081 catgaaccca aaggttacaa tgcaaatttc tgtgctggag cttgtccgta tctgtggagc
1141 tcagatactc aacatagccg ggtgctaagc ctgtacaaca ccattaatcc ggaagcatct
1201 gcctccccgt gttgcgtgtc tcaagattta gactccttga ccatcttgta ctacatcggg
1261 aataagccaa aaattgaaca gctttcaaat atgattgtaa aatcatgcaa gtgcagctaa
1321 aagaacaaaa aggggtaatg actccaactt attgatagtg ttttatgttc agataatgcc
1381 cgatgacttt gtcatgcagc tccaccgatt ttgagaacga cagcgacttc cgtcccagcc
1441 gtgccaggtg ctgcctcaga ttcaggttat gccgctcaat tcgctgcgta tatcgcttgc
1501 tgattacgtg cagctttccc ttcaggcggg attcatacag cggccagcca tccgtcatcc
1561 atatcaccac gtcaaagggt gacagcaggc tcataagacg ccccagcgtc gccatagtgc
1621 gttcaccgaa tacgtgcgca acaaccgtct tccggagact gtcatacgcg taaaacagcc
1681 agcgctggcg cgatttagcc ccgacatagc cccactgttc gtccatttcc gcgcagacga
1741 tgacgtcact gcccggctgt atgcgcgagg ttaccgactg cggcctgagt tttttaagtg
1801 acgtaaaatc gtgttgaggc caacgcccat aatgcgggct gttgcccggc atccaacgcc
1861 attcatggcc atatcaatga ttttctggtg cgtaccgggt tgagaagcgg tgtaagtgaa
1921 ctgcagttgc catgttttac ggcagtgaga gcagagatag cgctgatgtc cggcggtgct
1981 tttgccgtta cgcaccaccc cgtcagtagc tgaacaggag ggacagctga tagaaacaga
2041 agccactgga gcacctcaaa aacaccatca tacactaaat cagtaagttg gcagcatcac
2101 ccaaaaaggg caggattttt ttagggataa aaaaaaaaat gaaaatagtt caatcagtgt
2161 tacattgaaa aaaataaaat aaaatgcggt acttgtatgt ggaagatttt taggaaacaa
2221 aaattaaact ggcaacagat gcaaacattg aaggttttaa acttgcgttc cactggctta
2281 ataagacatt taatggagat ctttaaataa aaaatccctg tgttaaagca agacattcag
2341 gtgccaaaaa tgtctctcca gaatgcctgc caggatgagc ccatcaatta ttttttttac
2401 gttgattatg acctgattcc tttaccggta cgctatatta agcgttgaaa tagtacgtat
2461 tagtcttagt ttacctttga tgcctgtggc atagtcagta cacaaatctc ccatttaaaa
2521 aatagaaaca aaaagcaaca aaaagaattt ctaattttgg cccaaaaaaa aatgtagata
2581 tcaacatagg aaattctgcc taatgcagac aaaatttaga aatagaatgt ctcgctgttt
2641 ataaaccttt ttttttttaa cagtgtagag acgtttattt aaaaaataat aaacactgga
2701 agaatttgtt agtgttttta tgtgaaagga aaagaaaaac aggaataacc cattttgtgg
2761 tgttgctgtc ccatgcctta cttgatttct ctctattgtt ctgccttaag gcatcgtacc
2821 cattcctttt agtttgtagt tttgacagac attatttatt tgtgtggaat taagaagcag
2881 cctgtttttt tttgttacca ttgagtatgt ggacaaatga agaccaaaat aaactgctca
2941 aaccatgtaa tgctcaagag cacgtgttcc aacagtacac ggatatggcg accaccttca
3001 gtcatgcacc acttaaatgg ttccaatggc ccaaggcaca gtggacagta gcaaaatagt
3061 gtcttttctg gtactgaaaa ataatcccaa agcctgaaaa tggaaggtgc cgtagaatac
3121 cggagaatga tatactctgc cgatgagtag attttcaagt ctttgtttat ggttcggaca
3181 gaagggaaaa gctcaatcat aatgtcgcat gggactttga tcttgtgggt caatgggttt
3241 ttttttttat accaaaagac tttatttcaa cctggaaagg ctggaattga caatttttgg
3301 aaactttatt aaatatctta ataattccat cttgctgtcc acttaatcac agagggactg
3361 gaaatgtata ttgagtgata tcttccatgc gattatatat gctgtgtgtt aaagggacaa
3421 tttacaaagc tgaataaaac ctgcacattt ttttatgcat atacgccaat tttgccttta
3481 gtaaatgttg ttcttattgt
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