GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS HUMKER18B 756 bp ss-mRNA PRI 28-MAY-1991
DEFINITION Human mRNA fragment for cytokeratin 18
ACCESSION X12876
KEYWORDS cytokeratin; intermediate filament; keratin; keratin type I.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 756)
AUTHORS Romano,V., Hatzfeld,M., Magin,T.M., Zimbelmann,R., Franke,W.W.,
Maier,G. and Ponstingl,H.
TITLE Cytokeratin expression in simple epithelia:I. identification of
mRNA coding for human cytokeratin no. 18 by a cDNA clone
JOURNAL Differentiation 30, 244-253 (1986)
STANDARD full automatic
COMMENT SWISS-PROT; P05783; K1CR$HUMAN.
*source: tissue=liver; library=pEX; clone=pKH18;
From EMBL entry HSKER18A; dated 06-JUL-1989.
FEATURES Location/Qualifiers
mRNA <1..756
/note="cytokeratin 18 mRNA"
CDS <1..696
/note="cytokeratin 18 (232 AA)"
/codon_start=1
misc_feature 46..126
/note="alpha-helical domain 1B"
misc_feature 613..696
/note="alpha-helical domain 2"
polyA_site 756..756
/note="polyA site"
BASE COUNT 210 a 194 c 229 g 123 t
ORIGIN
1 ctggagacac agatcgaggc tctcaaggag gagctgctct tcatgaagaa gaaccacgaa
61 gaggaagtaa aaggcctaca agcccagatt gccagctctg ggttgaccgt ggaggtagat
121 gccccgaaat ctcaggacct ctccaagatc atggcagaca tccgggccca atatgacgag
181 ctggctcgga agaaccgaga ggagctagac aagtactggt ctcagcagat tgaggagagc
241 accacagtgg tcaccacaca gtctgctgag gttggagctg ctgagacgac gctcacagag
301 ctgagacgta cagtccagtc cttggagatc cgactggacc gcatgagaaa tctgaaggcc
361 agcttggaga acagcctgag ggaggtggag gcccgttacg ccctacagat ggagcagctc
421 aacgggatcc tgctgcacct tgagtcagag ctggcacaga cccgggcaga gggacagcgc
481 caggcccagg agtatgaggc cctgctgaac atcaaggtca agctggaggc tgagatcgcc
541 acctaccgcc gcctgctgga agatggcgag gactttaatc ttggtgatgc cttggacagc
601 agcaactcca tgcaaaccat ccaaaagacc accacccgcc ggatagtgga tggcaaagtg
661 gtgtctgaga ccaatgacac caaagttctg aggcattaag ccagcagaag acgggtacct
721 ttggggagca ggaggccaat aaaaagttca gagttc
//