GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMELA308 306 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human elastase III A gene, exon 8.
ACCESSION M18700 J03516 M18691
KEYWORDS elastase.
SEGMENT 8 of 8
SOURCE Human pancreas, cDNA to mRNA, clone pCL2; DNA, clone ELIII-39.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 306)
AUTHORS Tani,T., Ohsumi,J., Mita,K. and Takiguchi,Y.
TITLE Identification of a novel class of elastase isozyme, human
pancreatic elastase III, by cDNA and genomic gene cloning
JOURNAL J. Biol. Chem. 263, 1231-1239 (1988)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly provided
by T.Tani, 11-DEC-1987.
FEATURES Location/Qualifiers
prim_transcript <1..119
/note="EL III mRNA and introns"
intron <1..8
/note="EL III intron G"
CDS join(M18693:527..569,M18694:79..164,M18695:67..164,
M18696:45..176,M18697:6..142,M18698:21..163,
M18699:46..198,9..26)
/note="elastase III A precursor"
/codon_start=527
mat_peptide join(M18694:120..164,M18695:67..164,M18696:45..176,
M18697:45..176,M18698:21..163,M18699:46..198,9..23)
/note="elastase III A"
/codon_start=120
exon 9..26
/note="elastase III A precursor, exon 8"
mat_peptide 9..23
/note="elastase III A"
misc_feature 121..306
/note="putative VECTOR sequence Bacteriphage lambda
(J02459)"
BASE COUNT 74 a 74 c 70 g 88 t
ORIGIN About 2 kb after segment 7.
1 ttttccagac catagcaagc cactagaacc aaggcccagc tggcagtgct gatcgatccc
61 agctggcagt gctgatcgat cccacatcct gaataagaat aaagatccgg ggccttccca
121 gatccactcg ttattctcgg acgagtgttc agtaatgaac ctctggagag aaccatgtat
181 atgatcgtta tctgggttgg acttctgctt ttaagcccag ataactggcc tgaatatgtt
241 aatgagagaa tcggtattcc tcatgtgtgg catgttttcg tctttgctct tgcattttcg
301 ctagca
//