GenBank-Updates@genbank.bio.net (05/27/91)
LOCUS BOVDMC 4870 bp ss-mRNA MAM 27-MAY-1991
DEFINITION Bovine desmocollin mRNA, complete cds.
ACCESSION M67489 M61750
KEYWORDS cadherin; cell adhesion molecule; desmocollin.
SOURCE Bovine snout epitelial cell, cDNA to mRNA.
ORGANISM Bos taurus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE 1 (bases 1 to 4870)
AUTHORS Mechanic,S., Raynor,K., Hill,J.E. and Cowin,P.
TITLE Desmocollins form a novel subset of the cadherin family of cell
adhesion molecules
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88, 4476-4480 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 207..2726
/function="One of four major glycoproteins in the adhesive
cores of desmosomes; they are suggested to have a role in
initiating desmosome assembly and possibly in desmosomal
adhesion."
/product="'Desmocollin'"
/product="desmocollin"
/gene="desmocollin"
/codon_start=207
sig_peptide 207..293
/gene="desmocollin"
/codon_start=207
mat_peptide 603..2723
/product="desmocollin"
/gene="desmocollin"
/evidence=EXPERIMENTAL
/codon_start=603
polyA_signal 3251..3256
/note="'rare ATTAAA poly-adenylation signal'"
/gene="desmocollin"
/evidence=EXPERIMENTAL
polyA_signal 4829..4834
/gene="desmocollin"
/evidence=EXPERIMENTAL
BASE COUNT 1537 a 909 c 990 g 1428 t 6 others
ORIGIN
1 ggaaagcagt tgtcccattg ctccctctcc tgtcatttct cccgtttgcc tgctgacttt
61 tctccaaaca aagttcatcc cgcgccaaag tcggcaacag gttacctgcc caggtgccgg
121 ctgtggggaa tctgccgaag ccgccctgtg tattccaagc tgccctgtta tccagtcacc
181 atccctgagc atcaggacca cttctgatgg ctgtggcctc tgccgcccca gggagcatct
241 tctggaagca gctcctattc tctctcctgg ttttaatatt attttgcgat gcttgtcaga
301 aaatttctct tcaagttcct tctcatcttc gggctgaagc acttgtaggc aaagtgaatc
361 tgaaggagtg tctccagtcg gccagcctaa tcctgtcaag tgatcctgac ttcaggattc
421 tagaagatgg ctccatttac acaacacatg accttgtttt gtcttctgga aagagttttt
481 cgattttgct ctcagacagt cagggacagg ggcagaagga gatagaaatc atactggaag
541 caggaggaaa gaaggttcct aagagacata tgaaagacgc agtcctcagg cgaacgaaga
601 ggcgatgggc gcctattccg tgttcgctga tggagaactc actaggtcca tttccacagc
661 atgtgcagca ggttcagtct gatgctgcac aaaactacac catcttttac tccataagcg
721 gaccaggggt agacaaagag cccttcaatc tgttcttcat agaaaaagat acaggggata
781 tattttgtac aagaagcata gaccgtgagc aatatcaaga gtttccgatc tatgcctatg
841 cgaccactgc agatggttat gcacctgagt atccacttcc cctagtattc aaagttgaag
901 atgacaatga taatgcccca tattttgaaa acaaactgac cgtctttact gtgcctgaga
961 attgccgaac tggaacttca gtgggaaaag tgactgcaat agacctcgat gagcctgaca
1021 ctctacatac tcgtctgaag tacaaaatct tgcagcaaat tccaaacaat ccaagacatt
1081 tcactgtaca tccagacaca ggtgtcatca ccacaaccac acctttactg gatagagaaa
1141 aatgtgatac gtataagtta ataatggaag ttcgagacat ggggggccaa ccttttggtt
1201 tatttaacac aggaacaatt actatttctc ttgaggatga aaatgataat gcaccatatt
1261 ttacagaaac ttcttatact gtagaagtag aagaaaacag aattgatgtt gaaattttac
1321 gaatggcggt gcatgaccat gatttgccaa acacgccgca ctcgagggct gtgtaccaga
1381 tcctacaggg aaatgaaaac ggaaccttca aaattagtac agacccaaat acaaatgaag
1441 cggtcttgtg tgttgtcaag ccactgaact atgaagtcaa tcgccaagtt gttttgcaaa
1501 ttggtgtact taacgaagca caattcgcta aggcagtaaa ctcaaaaact actacgacta
1561 tgtgtactac agttgtcact gttaaagtta aagaccatga tgagggccct gagtgccagc
1621 caccagtaaa agtcattcag agtgaagact gcctccccgc aggcacagag ctccttggat
1681 acaaagcagt ggacccggaa aggggcactg gcgagggctt aaggtataag aagatacaag
1741 atgaagataa ctggtttgaa attaatgaat acactggtga cttgaaaact gtaaaagtgc
1801 tagatagaga atcaacattt gtaaaaaaca accaatacaa tgtttctgtg attgcgttcg
1861 atgcagatgg cagatcttgc actggaacgt tagtagtttt tttggaagat aaaaatgacc
1921 acccaccgca gataaaacaa gaagaactga caatttgccg gcatgataag gattatgttg
1981 tcctcgaacc tacagatcaa gatggacctg acaatgggcc accttttcaa ttcattcttg
2041 ataattctgc cagcaaactt tggacagtag agacaaggga tggtaaaact gccattcttc
2101 gggggcggca agatcttgat tatgactatt acactgttcc tatccaaata aaagacagac
2161 atggtgcttc tgcaacacac atattaccag tgagagtatg tgattgtaca attccatccg
2221 aatgtagaat gcctagtaaa ctttcgagag aggcagcact cgcaaatgta ttccttggaa
2281 aatgggcaat tcttgccatg gtgttgggtt ctgtattgtt gttatgtatt ttgttcacat
2341 gtttctgtgt tactgttaag aaaacagtaa agaagtgttt tccagaagat gtagcccagc
2401 aaaatttaat tgtatcaaat actgaaggac ctggagaaga agtgatggat gcaaatatta
2461 gactccccac acagacatcc aacgtttgtg acacaagcat atctgttggc acacttggtg
2521 gccagggagt caaaacacag caaagttttg agatggtcaa aggcggctac actttggatg
2581 ccaacaaagg aggtggacat cagaccctgg aatctgttaa gggagtgacg gacactggca
2641 gatacacgta cagtgactgg cacaacttca cccaacctcg gcttggcgaa gaatccatta
2701 gaggacacac tctggttaaa aattaaacag taaaagaagg tgtatctgtg cggacaagac
2761 gaggaacaca agctctgcga agactacgtt cgctcctata gctatgaagg caaagggtct
2821 gtggccggct cagtgggctg ctgcagcgat cggcaggaag aagaggggct tgacttccta
2881 gatcatctgg aacccaaatt taggacgcta gcgaaaacat gtgtaaagaa ataaaatgtg
2941 ccttttaata gcgtaacatc taccagcgca tattgaatgt aaaacaatag cagcatctgc
3001 taaagtattt gtttatggag gtaaacttcc agttgtgtat agataaggct cccttaaatt
3061 ctccttgtct gagataactt tagtcttctc tagacatcag tgcttccttt gttaatttcc
3121 ttttctatgc acgtacattt tcttgccctt tccaggacgg caccgtgtgc tttctcacac
3181 cttctgtttg aaaacttacg ttacttggta tgctctggaa gagtatgtga gggagttagg
3241 gattgtggag attaaagaaa aacacattgt tattttaaat gaaaatgaaa tattttcttc
3301 agaatcttgg gacaattatg cttttagaag tattgtcttt ggtgctacag aattgcttcc
3361 tttacctgaa tggctttgtg ctgaagaatt tcttatgcat tctctgatgc aatctttgat
3421 ttggtgaata agagctcatc tttcattgtg ttttcaccct gtggaggtgc tcccagcttg
3481 atcctgggat ctctgttgat gtggatgtgt tatcaggttc ctacaggttc tagaattgtt
3541 ggaaagatgt ggaccagaag aggctcacag aaatttgagt cattgagatt tttaaaaaaa
3601 aagcatttcc atgaaagaat tgcagcctta atgcccatgg gttgactgaa acatgcaaat
3661 ctgttttgtt ggcccatcat gatgtattat tactttttaa aaatgtaaat gccttggcaa
3721 ggacatgttc tctctagttt gacaccatcc caccatcctc aagcatttga gtaactagac
3781 cagtaggcat taggcttaca accctgatcg ccctttgaat gtgctaaaca ctgaatgact
3841 atccatactg gaatggatac tcaggctaca ttggtaatca ctttcagaaa atgttaaata
3901 agannnnnaa ggcattttaa taagatattc tattttatta ctttagaaaa aacccatata
3961 tttaaatatt ttaatatttt ttgtgccaaa ttctatagat tcataaaaca tttgcagtat
4021 atatcacaag gacattttca ttcagacaaa aaaacttttt ttcatctttt agctacttaa
4081 ccttcaaaaa aaaatgagtg actaattttc ttaaattttg tgaattattt tccttcttag
4141 tcacaggatc taaataaaga cgtttcttga aatgaaattg aatagtagag cagaataaat
4201 aagtagcttt agtaaataca gtttttattt taaacggcgc cctctatgta ttattttatg
4261 ggcattgtca gtaaaataat ttnggagagt aatgcagctt ctgaatatct gttatctgat
4321 gtacatgtta ttctgacaat gatgctagtt ttgaaatttt ataatattaa aattttggaa
4381 atatatcata ataatgttct aagttatatt tttgaacata ggtgcagaat gttgctgagc
4441 aattaaaaat aattagttga acattagcct acatgttatg tcttcgtatt tcttaaattt
4501 aaatgtgaaa aagaaaattt gtatctgaac ataaggtaca aataaagggc caaagctgat
4561 ttctcaaacc aacaagagaa gatactttaa aactatgacc agaattatta gaaagtgtag
4621 gaaatgaatt tgtattaagg aatttgacta ttttaagatg tttcaaaata tcattaaatt
4681 gttaaattgt atctcataga agaactatga tgtcttttga tttatttagg aatttcaaag
4741 ttattctcta gttaacactc aaaatcaaat gttaattgta tgattaatga aatttatgaa
4801 actctgctag actgttatga atttagttaa taaaatattg tatattaaaa aaaaaaaaaa
4861 aaaaaaaaaa
//GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS BOVDMC 4870 bp ss-mRNA MAM 30-MAY-1991
DEFINITION Bovine desmocollin mRNA, complete cds.
ACCESSION M67489 M61750
KEYWORDS cadherin; cell adhesion molecule; desmocollin.
SOURCE Bovine snout epithelial cell, cDNA to mRNA.
ORGANISM Bos taurus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE 1 (bases 1 to 4870)
AUTHORS Mechanic,S., Raynor,K., Hill,J.E. and Cowin,P.
TITLE Desmocollins form a novel subset of the cadherin family of cell
adhesion molecules
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88, 4476-4480 (1991)
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 207..2726
/function="One of four major glycoproteins in the adhesive
cores of desmosomes; they are suggested to have a role in
initiating desmosome assembly and possibly in desmosomal
adhesion."
/product="'Desmocollin'"
/product="desmocollin"
/gene="desmocollin"
/codon_start=207
sig_peptide 207..293
/gene="desmocollin"
/codon_start=207
mat_peptide 603..2723
/product="desmocollin"
/gene="desmocollin"
/evidence=EXPERIMENTAL
/codon_start=603
polyA_signal 3251..3256
/note="'rare ATTAAA poly-adenylation signal'"
/gene="desmocollin"
/evidence=EXPERIMENTAL
polyA_signal 4829..4834
/gene="desmocollin"
/evidence=EXPERIMENTAL
BASE COUNT 1537 a 909 c 990 g 1428 t 6 others
ORIGIN
1 ggaaagcagt tgtcccattg ctccctctcc tgtcatttct cccgtttgcc tgctgacttt
61 tctccaaaca aagttcatcc cgcgccaaag tcggcaacag gttacctgcc caggtgccgg
121 ctgtggggaa tctgccgaag ccgccctgtg tattccaagc tgccctgtta tccagtcacc
181 atccctgagc atcaggacca cttctgatgg ctgtggcctc tgccgcccca gggagcatct
241 tctggaagca gctcctattc tctctcctgg ttttaatatt attttgcgat gcttgtcaga
301 aaatttctct tcaagttcct tctcatcttc gggctgaagc acttgtaggc aaagtgaatc
361 tgaaggagtg tctccagtcg gccagcctaa tcctgtcaag tgatcctgac ttcaggattc
421 tagaagatgg ctccatttac acaacacatg accttgtttt gtcttctgga aagagttttt
481 cgattttgct ctcagacagt cagggacagg ggcagaagga gatagaaatc atactggaag
541 caggaggaaa gaaggttcct aagagacata tgaaagacgc agtcctcagg cgaacgaaga
601 ggcgatgggc gcctattccg tgttcgctga tggagaactc actaggtcca tttccacagc
661 atgtgcagca ggttcagtct gatgctgcac aaaactacac catcttttac tccataagcg
721 gaccaggggt agacaaagag cccttcaatc tgttcttcat agaaaaagat acaggggata
781 tattttgtac aagaagcata gaccgtgagc aatatcaaga gtttccgatc tatgcctatg
841 cgaccactgc agatggttat gcacctgagt atccacttcc cctagtattc aaagttgaag
901 atgacaatga taatgcccca tattttgaaa acaaactgac cgtctttact gtgcctgaga
961 attgccgaac tggaacttca gtgggaaaag tgactgcaat agacctcgat gagcctgaca
1021 ctctacatac tcgtctgaag tacaaaatct tgcagcaaat tccaaacaat ccaagacatt
1081 tcactgtaca tccagacaca ggtgtcatca ccacaaccac acctttactg gatagagaaa
1141 aatgtgatac gtataagtta ataatggaag ttcgagacat ggggggccaa ccttttggtt
1201 tatttaacac aggaacaatt actatttctc ttgaggatga aaatgataat gcaccatatt
1261 ttacagaaac ttcttatact gtagaagtag aagaaaacag aattgatgtt gaaattttac
1321 gaatggcggt gcatgaccat gatttgccaa acacgccgca ctcgagggct gtgtaccaga
1381 tcctacaggg aaatgaaaac ggaaccttca aaattagtac agacccaaat acaaatgaag
1441 cggtcttgtg tgttgtcaag ccactgaact atgaagtcaa tcgccaagtt gttttgcaaa
1501 ttggtgtact taacgaagca caattcgcta aggcagtaaa ctcaaaaact actacgacta
1561 tgtgtactac agttgtcact gttaaagtta aagaccatga tgagggccct gagtgccagc
1621 caccagtaaa agtcattcag agtgaagact gcctccccgc aggcacagag ctccttggat
1681 acaaagcagt ggacccggaa aggggcactg gcgagggctt aaggtataag aagatacaag
1741 atgaagataa ctggtttgaa attaatgaat acactggtga cttgaaaact gtaaaagtgc
1801 tagatagaga atcaacattt gtaaaaaaca accaatacaa tgtttctgtg attgcgttcg
1861 atgcagatgg cagatcttgc actggaacgt tagtagtttt tttggaagat aaaaatgacc
1921 acccaccgca gataaaacaa gaagaactga caatttgccg gcatgataag gattatgttg
1981 tcctcgaacc tacagatcaa gatggacctg acaatgggcc accttttcaa ttcattcttg
2041 ataattctgc cagcaaactt tggacagtag agacaaggga tggtaaaact gccattcttc
2101 gggggcggca agatcttgat tatgactatt acactgttcc tatccaaata aaagacagac
2161 atggtgcttc tgcaacacac atattaccag tgagagtatg tgattgtaca attccatccg
2221 aatgtagaat gcctagtaaa ctttcgagag aggcagcact cgcaaatgta ttccttggaa
2281 aatgggcaat tcttgccatg gtgttgggtt ctgtattgtt gttatgtatt ttgttcacat
2341 gtttctgtgt tactgttaag aaaacagtaa agaagtgttt tccagaagat gtagcccagc
2401 aaaatttaat tgtatcaaat actgaaggac ctggagaaga agtgatggat gcaaatatta
2461 gactccccac acagacatcc aacgtttgtg acacaagcat atctgttggc acacttggtg
2521 gccagggagt caaaacacag caaagttttg agatggtcaa aggcggctac actttggatg
2581 ccaacaaagg aggtggacat cagaccctgg aatctgttaa gggagtgacg gacactggca
2641 gatacacgta cagtgactgg cacaacttca cccaacctcg gcttggcgaa gaatccatta
2701 gaggacacac tctggttaaa aattaaacag taaaagaagg tgtatctgtg cggacaagac
2761 gaggaacaca agctctgcga agactacgtt cgctcctata gctatgaagg caaagggtct
2821 gtggccggct cagtgggctg ctgcagcgat cggcaggaag aagaggggct tgacttccta
2881 gatcatctgg aacccaaatt taggacgcta gcgaaaacat gtgtaaagaa ataaaatgtg
2941 ccttttaata gcgtaacatc taccagcgca tattgaatgt aaaacaatag cagcatctgc
3001 taaagtattt gtttatggag gtaaacttcc agttgtgtat agataaggct cccttaaatt
3061 ctccttgtct gagataactt tagtcttctc tagacatcag tgcttccttt gttaatttcc
3121 ttttctatgc acgtacattt tcttgccctt tccaggacgg caccgtgtgc tttctcacac
3181 cttctgtttg aaaacttacg ttacttggta tgctctggaa gagtatgtga gggagttagg
3241 gattgtggag attaaagaaa aacacattgt tattttaaat gaaaatgaaa tattttcttc
3301 agaatcttgg gacaattatg cttttagaag tattgtcttt ggtgctacag aattgcttcc
3361 tttacctgaa tggctttgtg ctgaagaatt tcttatgcat tctctgatgc aatctttgat
3421 ttggtgaata agagctcatc tttcattgtg ttttcaccct gtggaggtgc tcccagcttg
3481 atcctgggat ctctgttgat gtggatgtgt tatcaggttc ctacaggttc tagaattgtt
3541 ggaaagatgt ggaccagaag aggctcacag aaatttgagt cattgagatt tttaaaaaaa
3601 aagcatttcc atgaaagaat tgcagcctta atgcccatgg gttgactgaa acatgcaaat
3661 ctgttttgtt ggcccatcat gatgtattat tactttttaa aaatgtaaat gccttggcaa
3721 ggacatgttc tctctagttt gacaccatcc caccatcctc aagcatttga gtaactagac
3781 cagtaggcat taggcttaca accctgatcg ccctttgaat gtgctaaaca ctgaatgact
3841 atccatactg gaatggatac tcaggctaca ttggtaatca ctttcagaaa atgttaaata
3901 agannnnnaa ggcattttaa taagatattc tattttatta ctttagaaaa aacccatata
3961 tttaaatatt ttaatatttt ttgtgccaaa ttctatagat tcataaaaca tttgcagtat
4021 atatcacaag gacattttca ttcagacaaa aaaacttttt ttcatctttt agctacttaa
4081 ccttcaaaaa aaaatgagtg actaattttc ttaaattttg tgaattattt tccttcttag
4141 tcacaggatc taaataaaga cgtttcttga aatgaaattg aatagtagag cagaataaat
4201 aagtagcttt agtaaataca gtttttattt taaacggcgc cctctatgta ttattttatg
4261 ggcattgtca gtaaaataat ttnggagagt aatgcagctt ctgaatatct gttatctgat
4321 gtacatgtta ttctgacaat gatgctagtt ttgaaatttt ataatattaa aattttggaa
4381 atatatcata ataatgttct aagttatatt tttgaacata ggtgcagaat gttgctgagc
4441 aattaaaaat aattagttga acattagcct acatgttatg tcttcgtatt tcttaaattt
4501 aaatgtgaaa aagaaaattt gtatctgaac ataaggtaca aataaagggc caaagctgat
4561 ttctcaaacc aacaagagaa gatactttaa aactatgacc agaattatta gaaagtgtag
4621 gaaatgaatt tgtattaagg aatttgacta ttttaagatg tttcaaaata tcattaaatt
4681 gttaaattgt atctcataga agaactatga tgtcttttga tttatttagg aatttcaaag
4741 ttattctcta gttaacactc aaaatcaaat gttaattgta tgattaatga aatttatgaa
4801 actctgctag actgttatga atttagttaa taaaatattg tatattaaaa aaaaaaaaaa
4861 aaaaaaaaaa
//