GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATPOMCG1 872 bp ds-DNA ROD 28-MAY-1991
DEFINITION Rat gene for proopiomelanocortin (POMC) 5' flank and exon 1
ACCESSION X03171
KEYWORDS hormone; proopiomelanocortin.
SOURCE Rattus norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 872)
AUTHORS Drouin,J., Chamberland,M., Charron,J., Jeannotte,L. and Nemer,M.
TITLE Structure of the rat pro-opiomelanocortin (POMC) gene
JOURNAL FEBS Lett. 193, 54-58 (1985)
STANDARD full automatic
COMMENT EPD; 25006; Rn POMC (ACTH,b'LPH).
Sequences homologous to SV40-type core consensus enhancer sequence
were found around pos. 354, 465, 523 and 796, also sequences
homologous to adenovirus-type core consensus enhancer sequence
around pos. 454, 645 and 725. Regions with potential Z-DNA
formation are found around positions 342, 482 and 541.
From EMBL entry RNPOMCG1; dated 28-JAN-1986.
FEATURES Location/Qualifiers
promoter 645..653
/note="CAAT-like sequence"
promoter 651..659
/note="CAAT-like sequence"
promoter 657..665
/note="CAAT-like sequence"
promoter 681..686
/note="put. TATA-box"
precursor_RNA 712..>872
/note="POMC primary transcript"
mRNA 712..808
/note="exon 1"
intron 809..>872
/note="intron I"
BASE COUNT 200 a 266 c 223 g 181 t 2 others
ORIGIN
1 gaanngcttc cacttccctc cacagagtgc tgcacctcct ggttaatagt ctgaggctgg
61 caggaccttt cccttggagt ttgggcatca aagggcacct gtcttggaat aagtattggg
121 gatggagaca gactgtacaa actcacttgc acacactccc aaaggtagcc tgccttgggc
181 tgccatgatt cttgacagcc tctgttgtct cccttctcga aacgaaacag agatcttgat
241 ttcacaagac tccatacttt cccaacactg gggaaatctg atgcgtaaca gaccccctcc
301 tcattagtga tatttacctc caaatgccag gaaggcagat ggacgcacac aggtaattcc
361 actccattct gtaagacctc agaactaggc ctgcctcaca ccaggatgct aagcctctgt
421 ccagtcctga gtggagatcc aacagcatcc ttaattaagt tcctcctgac caccggggcc
481 aggtgtgcgc ttcagcgggt ctgtgctaac gccagcctcc gcactttcca ggcacatctg
541 ctgtgcgcgc agccccgacc gggaagcccc ccctcccgcg gcccgccgcc ccccttcgcg
601 tggccgggga ttcgcttgtt gcgttgcaga agcgctgcca ggaaggtcac gtccaaggct
661 cacccaccca accctgcagg tataaaagaa gagagaagag tgacagggac caaacgggag
721 gcgacggagg agaaaagagg ttaaggagca gtgactaaga gaggccactg aacatcttcg
781 tcctcagaga gctgcctttc cgcgacaggt aagggtgtct cggctcctga cggctctcct
841 acgctgagct ctgtccccgg accctgggat cc
//GenBank-Updates@genbank.bio.net (05/29/91)
LOCUS RATPOMCG2 263 bp ds-DNA ROD 28-MAY-1991
DEFINITION Rat gene for proopiomelanocortin (POMC) exon 2
ACCESSION X03176
KEYWORDS alternate splicing; hormone; proopiomelanocortin; signal peptide.
SOURCE Rattus norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 263)
AUTHORS Drouin,J., Chamberland,M., Charron,J., Jeannotte,L. and Nemer,M.
TITLE Structure of the rat pro-opiomelanocortin (POMC) gene
JOURNAL FEBS Lett. 193, 54-58 (1985)
STANDARD full automatic
COMMENT From EMBL entry RNPOMCG2; dated 28-JAN-1986.
FEATURES Location/Qualifiers
intron <1..18
/note="intron I"
mRNA 19..199
/note="exon 2"
misc_feature 48..49
/note="alternate splice site"
CDS 68..199
/note="POMC precursor"
/codon_start=68
CDS 68..145
/note="put. signal peptide (aa -26 to -1)"
/codon_start=68
BASE COUNT 49 a 78 c 80 g 56 t
ORIGIN
1 ttgttccgct ccttgcaggg gtccctccaa tcttgtttgc ctctgcagag cctcagccac
61 ctggaagatg ccgagattct gctacagtcg ctcaggggcc ctgctgctgg ccctcctgct
121 tcagacctcc atagacgtgt ggagctggtg cctggagagc agccagtgcc aggacctcac
181 cacggaaagc aacctgctgg tatgtgggcc acggacacca ctgtggcttg ggtggaagat
241 ggcaccggga ttagaacaga tgg
//GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS RATPOMCG2 263 bp ds-DNA ROD 30-MAY-1991
DEFINITION Rat gene for proopiomelanocortin (POMC) exon 2
ACCESSION X03176
KEYWORDS alternate splicing; hormone; proopiomelanocortin; signal peptide.
SOURCE Rattus norvegicus DNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 263)
AUTHORS Drouin,J., Chamberland,M., Charron,J., Jeannotte,L. and Nemer,M.
TITLE Structure of the rat pro-opiomelanocortin (POMC) gene
JOURNAL FEBS Lett. 193, 54-58 (1985)
STANDARD full automatic
COMMENT From EMBL entry RNPOMCG2; dated 28-JAN-1986.
FEATURES Location/Qualifiers
intron <1..18
/note="intron I"
mRNA 19..199
/note="exon 2"
misc_feature 48..49
/note="alternate splice site"
CDS 68..199
/note="POMC precursor"
/codon_start=68
CDS 68..145
/note="put. signal peptide (aa -26 to -1)"
/codon_start=68
BASE COUNT 49 a 78 c 80 g 56 t
ORIGIN
1 ttgttccgct ccttgcaggg gtccctccaa tcttgtttgc ctctgcagag cctcagccac
61 ctggaagatg ccgagattct gctacagtcg ctcaggggcc ctgctgctgg ccctcctgct
121 tcagacctcc atagacgtgt ggagctggtg cctggagagc agccagtgcc aggacctcac
181 cacggaaagc aacctgctgg tatgtgggcc acggacacca ctgtggcttg ggtggaagat
241 ggcaccggga ttagaacaga tgg
//