GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMMEDUR 920 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA for medullasin (leukocyte (neutrophil) elastase
ACCESSION X05875
KEYWORDS elastase; medullasin; protease; serine protease;
unidentified reading frame.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 792)
AUTHORS Okano,K., Aoki,Y., Sakurai,T., Kajitani,M., Kanai,S., Shimazu,T.,
Shimizu,H. and Naruto,M.
TITLE Molecular Cloning of Complementary DNA for Human Medullasin: an
Inflammatory Serine Protease in Bone Marrow Cells
JOURNAL J. Biochem. 102, 13-16 (1987)
STANDARD full automatic
REFERENCE 2 (bases 1 to 920)
AUTHORS Naruto,M.
JOURNAL Unpublished (1988)
STANDARD full automatic
COMMENT SWISS-PROT; P08246; ELNE$HUMAN.
*source: cell line=ML3 (acute promyelocytic cells); see y00477 for
genomic sequence and leader sequence derived from cDNA clone
Data kindly reviewed (09-MAR-1988) by Naruto M.
From EMBL entry HSMEDUR; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 39..839
/note="open reading frame"
/codon_start=39
CDS 126..839
/note="medullasin N-term."
/codon_start=126
misc_feature 900..905
/note="pot. polyA signal"
polyA_site 920..920
/note="polyA site"
BASE COUNT 141 a 329 c 287 g 163 t
ORIGIN
1 gcacggaggg gcagagaccc cggagcccca gccccaccat gaccctcggc cgccgactcg
61 cgtgtctttt cctcgcctgt gtcctgccgg ccttgctgct ggggggcacc gcgctggcct
121 cggagattgt ggggggccgg cgagcgcggc cccacgcgtg gcccttcatg gtgtccctgc
181 agctgcgcgg aggccacttc tgcggcgcca ccctgattgc gcccaacttc gtcatgtcgg
241 ccgcgcactg cgtggcgaat gtaaacgtcc gcgcggtgcg ggtggtcctg ggagcccata
301 acctctcgcg gcgggagccc acccggcagg tgttcgccgt gcagcgcatc ttcgaaaacg
361 gctacgaccc cgtaaacttg ctcaacgaca tcgtgattct ccagctcaac gggtcggcca
421 ccatcaacgc caacgtgcag gtggcccagc tgccggctca gggacgccgc ctgggcaacg
481 gggtgcagtg cctggccatg ggctggggcc ttctgggcag gaaccgtggg atcgccagcg
541 tcctgcagga gctcaacgtg acggtggtga cgtccctctg ccgtcgcagc aacgtctgca
601 ctctcgtgag gggccggcag gccggcgtct gtttcgggga ctccggcagc cccttggtct
661 gcaacgggct aatccacgga attgcctcct tcgtccgggg aggctgcgcc tcagggctct
721 accccgatgc ctttgccccg gtggcacagt ttgtaaactg gatcgactct atcatccaac
781 gctccgagga caacccctgt ccccaccccc gggacccgga cccggccagc aggacccact
841 gagaagggct gcccgggtca cctcagctgc ccacacccac actctccagc atctggcaca
901 ataaacattc tctgttttgt
//