GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMMGSAG 1895 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human gene for melanoma growth stimulatory activity (MGSA)
ACCESSION X54489
KEYWORDS beta-thromboglobulin; beta-thromboglobulin superfamily;
growth factor; melanoma growth stimulatory activity.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1895)
AUTHORS Richmond,A.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1895)
AUTHORS Baker,N.E., Kucera,G. and Richmond,A.
TITLE Nucleotide sequence of the human melanoma growth stimulatory
activity (MGSA) gene
JOURNAL Nucleic Acids Res. 18, 6453-6453 (1990)
STANDARD full automatic
COMMENT *source: tissue=blood; library=lambda fix blood genomic;
See also X12510.
From EMBL entry HSMGSAG; dated 19-DEC-1990.
FEATURES Location/Qualifiers
mat_peptide join(330..451,565..648,1180..1195)
/product="melanoma growth stimulatory activity protein"
/gene="MGSA"
mRNA join(51..229,328..451,565..648,1180..1895)
/gene="MGSA"
CDS join(130..229,328..451,565..648,1180..1195)
/product="melanoma growth stimulatory activity preprotein"
/gene="MGSA"
/codon_start=130
TATA_signal 21..27
exon 51..229
/number=1
/gene="MGSA"
exon 51..229
/gene="MGSA"
prim_transcript 51..1895
/gene="MGSA"
sig_peptide 130..329
intron 230..327
/number=1
exon 328..451
/number=2
/gene="MGSA"
exon 328..451
/gene="MGSA"
exon 328..451
/gene="MGSA"
intron 452..564
/number=2
exon 565..648
/number=3
/gene="MGSA"
exon 565..648
/gene="MGSA"
exon 565..648
/gene="MGSA"
exon 565..648
/gene="MGSA"
intron 649..1179
/number=3
exon 1180..1895
/number=4
/gene="MGSA"
exon 1180..1895
/gene="MGSA"
BASE COUNT 466 a 501 c 450 g 478 t
ORIGIN
1 gctttccagc cccaaccatg cataaaaggg gttcgcggat ctcggagagc cacagagccc
61 gggccgcagg cacctcctcg ccagctcttc cgctcctctc acagccgcca gacccgcctg
121 ctgagcccca tggcccgcgc tgctctctcc gccgccccca gcaatccccg gctcctgcga
181 gtggcactgc tgctcctgct cctggtagcc gctggccggc gcgcagcagg tgggtaccgg
241 cgccctgggg tccccgggcc ggacgcggct ggggtaggca cccagcgccg acagcctcgc
301 tcagtcagtg agtctcttct tccctaggag cgtccgtggc cactgaactg cgctgccagt
361 gcttgcagac cctgcaggga attcacccca agaacatcca aagtgtgaac gtgaagtccc
421 ccggacccca ctgcgcccaa accgaagtca tgtaagtccc gccccgcgct gcctctgcca
481 ccgccggggt cccagaccct cctgctgccc caaccctgtc cccagcccga cctcctgcct
541 cacgagattc ccttccctct gcagagccac actcaagaat gggcggaaag cttgcctcaa
601 tcctgcatcc cccatagtta agaaaatcat cgaaaagatg ctgaacaggt gagttatggt
661 ttccatgtac acaggcgact ggagccgttg gtcagaaata ctggcatgtg ccccctaaaa
721 ataaaatcag gaaaacccag gggttagttg aaggactaga aattgggatt attgttttca
781 caattaaggt ttcctttacg ataattactg ctctggtgcc agaggatatt cccaatgcct
841 ggcgtcccca ccctggttct tccttcgttc caatgaatgt aggtaaaact gccttcattt
901 gaggcccagt aggacaaaca gcaacaggtt ctggctgttt ttaatccaat agtacagtgg
961 agaccaccgc cccaccccac ccccattcct aaaagagcat cccaagctta gaggtccctg
1021 ccacacagca cagctgtcat aggcagtagc cacttggttg ccaggctggg gaaactgcat
1081 tcggagaact ctagaggctg gaggagcagg gcaggagaag agtgttgtgc aatcagcttt
1141 cccgagcacc tactcagggc acccattttc tcattgcagt gacaaatcca actgaccaga
1201 agggaggagg aagctcactg gtggctgttc ctgaaggagg ccctgccctt ataggaacag
1261 aagaggaaag agagacacag ctgcagaggc cacctggatt gtgcctaatg tgtttgagca
1321 tcgcttagga gaagtcttct atttatttat ttattcatta gttttgaaga ttctatgtta
1381 atattttagg tgtaaaataa ttaagggtat gattaactct acctgcacac tgtcctatta
1441 tattcattct ttttgaaatg tcaaccccaa gttagttcaa tctggattca tatttaattt
1501 gaaggtagaa tgttttcaaa tgttctccag tcattatgtt aatatttctg aggagcctgc
1561 aacatgccag ccactgtgat agaggctggc ggatccaagc aaatggccaa tgagatcatt
1621 gtgaaggcag gggaatgtat gtgcacatct gttttgtaac tgtttagatg aatgtcagtt
1681 gttatttatt gaaatgattt cacagtgtgt ggtcaacatt tctcatgttg aaactttaag
1741 aactaaaatg ttctaaatat cccttggaca ttttatgtct ttcttgtaag gcatactgcc
1801 ttgtttaatg gtagttttac agtgtttctg gcttagaaca aaggggctta attattgatg
1861 ttttcataga gaatataaaa ataaagcact tatag
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