GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMNFIL6 1910 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human gene for nuclear factor NF-IL6
ACCESSION X52560
KEYWORDS DNA-binding protein; NF-IL6 gene; leucine zipper; nuclear factor;
transcription factor.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1910)
AUTHORS Kishimoto,T.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1910)
AUTHORS Akira,S., Isshiki,H., Sugita,T., Tanabe,O., Kinoshita,S.,
Nishio,Y., Nakajima,T., Hirano,T. and Kishimoto,T.
TITLE A nuclear factor for IL-6 expression (NF-IL6) is a member of a
C/EBP family.
JOURNAL EMBO J. 9, 1897-1906 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17676; NFL6$HUMAN. TFD; C138; Release 2. TFD; C139;
Release 2.
*source: library=EMBL3; clone=G16; tissue=placenta;
Data kindly reviewed (23-JUL-1990) by Kishimoto T.
From EMBL entry HSNFIL6; dated 02-OCT-1990.
FEATURES Location/Qualifiers
promoter 67..73
/note="TATA box"
precursor_RNA 95..>94
/note="primary transcript"
CDS 299..1333
/note="nuclear factor NF-IL6 (AA 1-345)"
/codon_start=299
misc_feature 1895..1900
/note="polyA signal"
BASE COUNT 336 a 669 c 593 g 306 t 6 others
ORIGIN
1 gtccttcgcg tcccggcggc gcggcggagg ggccggcgtg acgcagcggt tgctacgggc
61 cgcccttata aataaccggg ctcaggagaa actttagcga gtcagagccg cgcacgggac
121 tgggaagggg acccacccga gggtccagcc accagccccc tcactaatag cggccacccc
181 ggcagcggcg gcagcagcag cagcgacgca gcggcgacag ctcagagcag ggaggccgcg
241 cacctgcggg ccggccggag cgggcagccc caggccccct ccccgggcac ccgcgttcat
301 gcaacgcctg gtggcctggg acccagcatg tctccccctg ccgccgccgc cgcctgcctt
361 taaatccatg gaagtggcca acttctacta cgaggcggac tgcttggctg ctgcgtacgg
421 cggcaaggcg gcccccgcgg cgccccccgc ggccagaccc gggccgcgcc cccccgccgg
481 cgagctgggc agcatcggcg accacgagcg cgccatcgac ttcagcccgt acctggagcc
541 gctgggcgcg ccgcaggccc cggcgcccgc cacggccacg gacaccttcg aggcggctcc
601 gcccgcgccc gcccccgcgc ccgcctcctc cgggcagcac cacgacttcc tctccgacct
661 cttctccgac gactacgggg gcaagaactg caagaagccg gccgagtacg gctacgtgag
721 cctggggcgc ctgggggctg ccaagggcgc gctgcacccc ggctgcttcg cgcccctgca
781 cccaccgccc ccgccgccgc cgccgcccgc cgagctcaag gcggagccgg gcttcgagcc
841 cgcggactgc aagcggaagg aggaggccgg ggcgccgggc ggcggcgcag gcatggcggc
901 gggcttcccg tacgcgctgc gcgcttacct cggctaccag gcggtgccga gcggcagcag
961 cgggagcctc tccacgtcct cctcgtccag cccgcccggc acgccgagcc ccgctgacgc
1021 caaggccccc ccgaccgcct gctacgcggg ggccgggccg gcgccctcgc aggtcaagag
1081 caaggccaag aagaccgtgg acaagcacag cgacgagtac aagatccggc gcgagcgcaa
1141 caacatcgcc gtgcgcaaga gccgcgacaa ggccaagatg cgcaacctgg agacgcagca
1201 caaggtcctg gagctcacgg ccgagaacga gcggctgcag aagaaggtgg agcagctgtc
1261 gcgcgagctc agcaccctgc ggaacttgtt caagcagctg cccgagcccc tgctcgcctc
1321 ctccggccac tgctagcgcg gcccccgcgg cgtccccctg gggccggccg gggctgagac
1381 tccggggagc gcccgcgccc gcgccctcgc ccccnccccc nnnnccgcaa aactttggca
1441 ctggggcact tggcagcngg ggagcccgtc ggtaatttta atattttatt atatatatat
1501 atctatattt tgccaaccaa ccgtacatgc agatggctcc cgcccgtggt gtataaagaa
1561 gaaatgtcta tgtgtacaga tgaatgataa actctctgct ctccctctgc ccctctccag
1621 gcccggcggg cggggccggt ttcgaagttg atgcaatcgg tttaaacatg gctgaacgcg
1681 tgtgtacacg ggactgacgc aacccacgtg taactgtcag ccgggccctg agtaatcgct
1741 taaagatgtt ctagggcttg ttgctgttga tgttttgttt tgttttgttt tttggtcttt
1801 ttttgtatta taaaaaataa tctatttcta tgagaaaaga ggcgtctgta tattttggga
1861 atcttttccg tttcaagcaa ttaagaacac ttttaataaa cttttttttg
//