GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS RSHBCNP 3181 bp ss-mRNA VRL 30-MAY-1991
DEFINITION Human respiratory syncytial virus 1B, 1C, N, and P genes.
ACCESSION D00736 D00386 D00387 D00388 D00389 D00390 D00391 D00527
KEYWORDS 1B protein; 1C protein; N protein; P protein;
nonstructural protein; phosphoprotein.
SOURCE Human respiratory syncytial virus (strain 18537; subgroup B), cDNA
to mRNA from infected HEp-2 cells, clones C9, G15, B53, E41, R4,
F5, D35, C85, AA75, and 7N30.
ORGANISM Human respiratory syncytial virus
Viridae; ss-RNA enveloped viruses; Negative strand RNA viruses;
Paramyxoviridae; Pneumovirus.
REFERENCE 1 (bases 504 to 560; 1024 to 1089; 2253 to 2294)
AUTHORS Johnson,P.R. and Collins,P.L.
TITLE The A and B subgroups of human respiratory syncytial virus:
Comparison of intergenic and gene-overlap sequences
JOURNAL J. Gen. Virol. 69, 2901-2906 (1988)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 2330)
AUTHORS Johnson,P.R. and Collins,P.L.
TITLE The 1B(NS2), 1C(NS1) and N proteins of human respiratory syncytial
virus (RSV) of antigenic subgroups A and B: sequence conservation
and divergence within RSV genomic RNA
JOURNAL J. Gen. Virol. 70, 1539-1547 (1989)
STANDARD full staff_review
REFERENCE 3 (bases 2275 to 3181)
AUTHORS Johnson,P.R. and Collins,P.L.
TITLE Sequence comparison of the phosphoprotein mRNAs of antigenic
subgroups A and B of human respiratory syncytial virus identifies a
highly divergent domain in the predicted protein
JOURNAL J. Gen. Virol. 71, 481-485 (1990)
STANDARD full staff_review
COMMENT The nucleotide at 2271 is reported 'a' in [2], and 'aa' in [1],
although there is no comment about the difference in [2].
FEATURES Location/Qualifiers
CDS 46..465
/note="1C protein"
misc_feature 511..523
/note="1C gene end-sequence"
misc_feature 541..549
/note="1B gene start-sequence"
CDS 573..947
/note="1B protein"
misc_feature 1029..1040
/note="1B gene end-sequence"
misc_feature 1067..1075
/note="N gene start-sequence"
CDS 1085..2260
/note="N protein"
misc_feature 2261..2271
/note="N gene end-sequence"
misc_feature 2275..2283
/note="P gene start-sequence"
CDS 2292..3017
/note="P protein"
misc_feature 3176..3181
/note="P gene end-sequence"
BASE COUNT 1262 a 550 c 569 g 800 t
ORIGIN
1 aagaatttga taagtgctat ttaaatctaa ccttttcaat cagaaatggg gtgcaattca
61 ctgagcatga taaaggttag attacaaaat ttatttgaca atgacgaagt agcattgtta
121 aaaataacat gttatactga caaattaatt cttctgacca atgcattagc caaagcagta
181 atacatacaa ttaaattaaa cggcatagtt tttatacatg ttataacaag cagtgaagtg
241 tgccctgaca acaatattgt agtgaaatct aactttacaa caatgccaat attacaaaac
301 ggaggataca tatgggaatt gattgagttg acacactgct ctcaatcaaa tggtctaatg
361 gttgataatt gtgaaatcaa attttctaaa agactaagtg actcagtaat gactaattat
421 atgaatcaaa tatctgattt acttgggctt gatctcaatt catgaattat gtttagtcta
481 atttaataga catgtgttta tcaccatttt agttaatata aaacctcatc aaagggaaat
541 ggggcaaatg aactcaccta atcagtcaaa ccatgagcac tacaaatgac aacactacta
601 tgcaaagatt gatgatcaca gacatgagac ccctgtcgat ggaatcaata ataacttctc
661 tcaccaaaga aatcataaca cacaaattca tatacttgat aaacaatgaa tgtattgtaa
721 gaaaacttga tgaaagacaa gctacattta cattcttagt caattatgag atgaagctat
781 tgcacaaagt agggagtacc atatacaaga aatacactga atataataca aaatatggca
841 ctttccccat gcctatattt atcaatcatg acgggtttct agaatgtatt ggcattaagc
901 ctacaaaaca cactcctata atatacaaat atgacctcaa cccgtaaatt ccaacaaaaa
961 actaacccat ccaaactaag ctattcctca aacaacagtg ctcaacagtt aagaaggagc
1021 taatccattt tagtaattaa aaataaaggt agagccaata acataaattg gggcaaatac
1081 aaagatggct cttagcaaag tcaagttaaa tgatacatta aataaggatc agctgctgtc
1141 atccagcaaa tacactattc aacgtagtac aggagataat attgacactc ccaattatga
1201 tgtgcaaaaa cacctaaaca aactatgtgg tatgctatta atcactgaag atgcaaatca
1261 taaattcaca ggattaatag gtatgttata tgctatgtcc aggttaggaa gggaagacac
1321 tataaagata cttaaagatg ctggatatca tgttaaagct aatggagtag atataacaac
1381 atatcgtcaa gatataaatg gaaaggaaat gaaattcgaa gtattaacat tatcaagctt
1441 gacatcagaa atacaagtca atattgagat agaatctaga aagtcctaca aaaaactgct
1501 aaaagagatg ggagaagtgg ctccagaata taggcatgat tctccagact gtgggatgat
1561 aatactgtgt atagctgcac ttgtaataac caagttagca gcaggagata gatcaggtct
1621 tacagcagta attaggaggg caaacaatgt cttaaaaaac gaaataaaac gctacaaggg
1681 cctcatacca aaggatatag ctaacagttt ttatgaagtg tttgaaaaac accctcatct
1741 tatagatgtt tttgtgcact ttggcattgc acaatcatcc acaagagggg gtagtagagt
1801 tgaaggaatc tttgcaggat tatttatgaa tgcctatggt tcagggcaag taatgctaag
1861 atggggagtt ctagccaaat ctgtaaaaaa tatcatgcta ggacatgcta gtgtccaggc
1921 agaaatggaa caagttgtgg aagtttatga gtatgcacag aagttgggag gagaagctgg
1981 attctaccat atattgaaca atccaaaagc atcattgctg tcattaactc aatttcctaa
2041 cttctcaagt gtggtcctag gcaatgcagc aggtctaggc ataatgggag agtatagagg
2101 tacaccaaga aaccaagatc tatatgatgc ggccaaagca tatgcagagc aactcaaaga
2161 aaatggagta ataaactaca gtgtattaga cttaacagca gaagaattgg aagccataaa
2221 gcatcaactc aaccccaaag aagatgatgt agagctttaa gttaacaaaa atacggggca
2281 aataagtcaa catggagaag tttgcacctg aatttcatgg agaagatgca aacaacaaag
2341 ctaccaaatt cctagaatca ataaagggca agtttgcatc atccaaagat cctaagaaga
2401 aagatagcat aatatctgtt aactcaatag atatagaagt aactaaagag agcccgataa
2461 catctggcac caacatcatc aatccaataa gtgaagctga tagtacccca gaagctaaag
2521 ccaactaccc aagaaaaccc ctagatagct tcaaagaaga tctcacccca agtgacaacc
2581 ccttttctaa gttgtacaaa gaaacaatag aaacatttga taacaatgaa gaagaatcta
2641 gctactcata tgaagaaata aatgatcaaa caaatgacaa cattacagca agactagata
2701 gaattgatga aaaattaagt gaaatattag gaatgctcca tacattagta gttgcaagtg
2761 caggacccac ctcagctcgc gatggaataa gagatgctat ggttggtcta agagaagaaa
2821 tgatagaaaa aataagagcg gaagcattaa tgaccaatga taggttagag gctatggcaa
2881 gacttaggaa tgaggaaagc gaaaaaatgg caaaagacac ctcagatgaa gtgtctctta
2941 atccaacttc caaaaaattg agtaatttgt tggaagacaa cgatagtgac aatgatctat
3001 cacttgatga tttttgatca gtgatcaact cactcagcaa tcaacaacat caatgaaaca
3061 gacatcaatc cattgaatca actgccagac tgaacacaca aacgtccatc agcagaacta
3121 ccaaccaatc aatcaaccaa ttgatcaatc agcgacctaa caaaattaac aatatagtaa
3181 c
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