GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMP3RNA 799 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA for proteinase 3 (PR-3), Wegner's autoantigen
ACCESSION X56132
KEYWORDS Wegener's autoantigen; proteinase; signal peptide.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 799)
AUTHORS Jenne,D.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 112)
AUTHORS Jenne,D.E., Tschopp,J., Ludemann,J., Utecht,B. and Gross,W.L.
TITLE Wegener's autoantigen decoded
JOURNAL Nature 346, 520-520 (1990)
STANDARD full automatic
COMMENT From EMBL entry HSP3RNA; dated 22-OCT-1990.
FEATURES Location/Qualifiers
CDS <1..713
/note="proteinase 3 precursor (AA 238) (1 is 2nd base in
codon)"
/codon_start=1
CDS <1..20
/note="signal peptide (AA 7) (1 is 2nd base in codon)"
/codon_start=1
CDS 21..26
/note="put. propeptide (AA 2)"
/codon_start=21
CDS 27..713
/note="mat. proteinase 3 (AA 229)"
/codon_start=27
CDS 69..713
/note="alternative reading frame (AA 215)"
/codon_start=69
BASE COUNT 140 a 290 c 229 g 140 t
ORIGIN
1 tgagcggtgc tgcccgagct gcggagatcg tgggcgggca cgaggcgcag ccacactccc
61 ggccctacat ggcctccctg cagatgcggg ggaacccggg cagccacttc tgcggaggca
121 ccttgatcca ccccagcttc gtgctgacgg ccgcgcactg cctgcgggac ataccccagc
181 gcctggtgaa cgtggtgctc ggagcccaca acgtgcggac gcaggagccc acccagcagc
241 acttctcggt ggctcaggtg tttctgaaca actacgacgc ggagaacaaa ctgaacgaca
301 ttctcctcat ccagctgagc agcccagcca acctcagtgc ctccgtcacc tcagtccagc
361 tgccacagca ggaccagcca gtgccccacg gcacccagtg cctggccatg ggctggggcc
421 gcgtgggtgc ccacgacccc ccagcccagg tcctgcagga gctcaatgtc accgtggtca
481 ccttcttctg ccggccacat aacatttgca ctttcgtccc tcgccgcaag gccggcatct
541 gcttcggaga ctcaggtggc cccctgatct gtgatggcat catccaagga atagactcct
601 tcgtgatctg gggatgtgcc acccgccttt tccctgactt cttcacgcgg gtagccctct
661 acgtggactg gatccgttct acgctgcgcc gtgtggaggc caagggccgc ccctgaaccg
721 cccctcccac agcgctggcc gggaccccga gcctggctcc aaaccctcga ggcggatctt
781 tggacagaag cagctcttg
//