GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMPPAE1 813 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human preproacrosin gene exon 1 (EC 3.4.21.10)
ACCESSION X54017 X17349
KEYWORDS acrosin; preproacrosin.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 813)
AUTHORS Keime,S.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 1 to 813)
AUTHORS Keime,S., Adham,I.M. and Engel,W.
TITLE Nucleotide sequence and exon-intron organization of the human
proacrosin gene
JOURNAL Eur. J. Biochem. 190, 195-200 (1990)
STANDARD full automatic
COMMENT *source: cell type=leucocyte; See <X54017> to <X54020> for exons
1-5
Data kindly reviewed (29-AUG-1990) by Kaime A.R.S.
From EMBL entry HSPPAE1; dated 01-OCT-1990.
FEATURES Location/Qualifiers
precursor_RNA 587..>586
/note="primary transcript"
mRNA 587..737
/note="exon 1"
CDS 661..737
/note="preproacrosin (AA -19 to 7) (737 is 2nd base in
codon)"
/codon_start=661
CDS 661..717
/note="signal peptide (AA -19 to -1)"
/codon_start=661
CDS 718..737
/note="proacrosin (AA 1 - 7) (737 is 2nd base in codon)"
/codon_start=718
intron 738..>813
/note="intron I"
BASE COUNT 202 a 187 c 249 g 175 t
ORIGIN
1 cccttgagac ttaagctata ggaggaacca gacgttcctc acctaggcta ccagcaaagc
61 cgatggtcag actacttaga atctactagg aggagacgcg tcatattagg ctacggacag
121 gcaacggtgg gctttgacgc agttagccaa attcaaaatg actcttggaa aagtgtgttg
181 atagcattca cttggaagag gaaaagaaaa actttccccg aacaacaatt aaggatcaat
241 taatctgctg accctgactc ctctgatcca caaacatgtt gcaccgtctc atcactgaag
301 ggtgagccgc tcctcagtct gtgagtctgc agtggacagc acgcatgaga ggcagactct
361 gaacctgcac aaaagccaga gccttgggtg atgtggggac ctcgcaagag ttactgggaa
421 tggagatcct ggccttggga cagagggagt ggggctgcac aggagtcccc atcatcctgg
481 tggtggggga gcctatgtag gaagtcaaga agtctcttca gcacaaacca gttaaggcga
541 ggggctctta cctggcctga ctgctggggg tgggggtggg ggtcacccct gactgattgg
601 ccaggcagcc acggagcttt gtgaggtcac taggcttgca ggccaggcag tgccaggagt
661 atggttgaga tgctaccaac tgccattctg ctggtcttgg cagtgtccgt ggttgctaaa
721 gataacgcca cgtgtgagta agtgtcgggg caccttggtg ggggaaggat cttctgagga
781 gcaggtacca cacatgtgga ggcagcttgc tga
//