GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMPRB3L 4516 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human gene PRB3L for proline-rich protein G1
ACCESSION X07881
KEYWORDS PRB3L gene; proline-rich protein; proline-rich protein G1;
protein G1.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4516)
AUTHORS Lyons,K.M.
JOURNAL Unpublished (1988)
STANDARD full automatic
REFERENCE 2 (bases 1812 to 2934)
AUTHORS Lyons,K.M., Stein,J.H. and Smithies,O.
TITLE Length polymorphisms in human proline-rich protein genes generated
by intragenic unequal crossing over
JOURNAL Genetics 120, 267-278 (1988)
STANDARD full automatic
COMMENT **map: chromosomal location=chromosome 12p13.2;
From EMBL entry HSPRB3L; dated 24-JUL-1990.
FEATURES Location/Qualifiers
promoter 437..442
/note="TATA-box"
precursor_RNA 469..4184
/note="primary transcript"
mRNA 469..565
/note="Exon 1"
CDS 502..565
/note="G1 protein (AA 1 - 21) (565 is 1st base in codon)"
/codon_start=502
intron 566..1500
/note="Intron I"
mRNA 1501..1536
/note="Exon 2"
CDS 1501..1536
/note="G1 protein (AA 22 - 33) (1501 is 2nd base in codon)
(1536 is 1st base in codon)"
/codon_start=1501
intron 1537..2086
/note="Intron II"
mRNA 2087..2933
/note="Exon 3"
CDS 2087..2913
/note="G1 protein (AA 34 - 309) (2087 is 2nd base in
codon)"
/codon_start=2087
intron 2934..4081
/note="Intron III"
mRNA 4082..4184
/note="Exon 4"
misc_feature 4170..4175
/note="polyA signal"
polyA_site 4184..4184
/note="polyA site"
BASE COUNT 1316 a 1126 c 938 g 1136 t
ORIGIN
1 cctaatgtga tactctctgt acacacacat cacgagagat ggaaataggc tataaaaaca
61 gccagagata ttgatcatca tcaccgctgg ctgtagcttc actgcccaca cacacataca
121 cagaaataaa tagcaaagtt gaaagtggac aatagtctta ccaaaaagat tgaaactcta
181 atgacgtctg aagttcaatt atgacaccgt gctgattgct tggacacagt tcctttaaaa
241 cctttgttca agtcatagtt gtacctttta gaaataaggt acaaacaaca tccaacccaa
301 cctgttcctc tgggctagag tcccagacag aaataaggga tacacctgac ctgcagtaag
361 gaaagcagaa cccagtctct gggtggtgag gcccacccag tgtggagctc aaaggtgcca
421 ctgttctgct cctctttata aagggagctg ccatggttct cccagcacag agttgggagt
481 gactccagag cctccagcaa gatgctactg attctgctgt cggtggccct gctggccctg
541 agctcagctc agagcttaaa tgaaggtaag acagaaggag gagaagatgt ggtgactctg
601 cttggggctt aggaggtgat agttgtaatt atggggaaga gaggagaatg aaaacacaga
661 tggggctgca gaggtttcat gcctaggatc aggagacctg ttgtgccctc attccacacc
721 aagggcttct aatttattta atgtacaatg aaaatccaat aaagaatttg taccagggga
781 atgagaaggt aagatttgca tttatagaga gatagaactg tgctgtgaag gatgcagtgg
841 tgaatgcaag gcagattcag gaaagtccag ctgtgaagat cctaaactga tctcagtaag
901 tacacaggga tgatggtggc cttgctctac ctagtggatc agcattgatg atggagataa
961 acacacatta gagatactgc agagacagaa ctggataaaa cacttgcctg tgtctaacta
1021 cagatataga aatatcagat tcaatcattg tgatttttct ttcccctaca cacagtattt
1081 caatgtgctg ggagtggtat aggtaagatt gtattgaaac aattacttct ggttaccgaa
1141 ttgagaaagc ttgtgaatat agcaatgtat ttataggaga tggagggcat aagaatacca
1201 aaatatcaca ttgaagtacc tggcatgtgt aaactaaatt agcattaagt cttgaaggat
1261 gctagggaag aaaaaaaggg gctcttctat attgagttca tggctgttgc tctgtgtggt
1321 aacaaccctg cctcccctta caccttcctc cccttccagc agcttcacag atggtagctg
1381 acgagctaac ctaggggatg catggggtgt ggtgagaagt cccctttccc tgtagaacac
1441 ctgtgaatct tgcaaaattc gagatgtaac ctttcccatc atcctgtgct tctcttctag
1501 atgtcagcca ggaagaatct ccctccgtaa tatcaggtaa atcccaattc actctcaatc
1561 tgttttaact atcttcttct gcttatgaat ggatcagttc tccagtgtct tctcaccaac
1621 attttccttt agaaattgat taatattagt ccccctaata atgcaggcaa tcttcatgca
1681 accttgattt tggggaccat gagcagggcc accaaattga atggcagaga tgcttggctt
1741 agatgaaaac gggagtgggt tgacttccct cctgccagga gtgcctgctg ggagatgaca
1801 gacaaatggc cagtgtcctt attctgactc ctccttagac tgagagcccc tcaactgctt
1861 ccttcttctc cagcattcca ctccagagtt ctagagcttc actgaaaatg caaagaaatt
1921 agtgtctggg tcttattttt gtgcatttcc ccatttagct gcgttactgt aaaaatttgc
1981 ggcaactatt cagtgaatgc cgtgtgtccc ccacctcctc caggaaagcc agaaggacga
2041 cgcccacaag gaggaaacca gccccaacgt accccacctc ctctaggaaa gccagaagga
2101 cgacccccac aaggaggcaa ccagtcccaa ggtcccccac ctcgtccagg aaagccagaa
2161 ggaccacccc cacaaggagg aaaccagtcc caaggtcccc cacctcgtcc gggaaagcca
2221 gaaggacaac ccccacaagg aggaaaccag tcccaaggtc ccccacctcg tccgggaaag
2281 ccagaaggac cacccccaca aggaggaaac cagtcccaag gtcccccgcc tcgtccggga
2341 gagccagaag gaccaccccc acaaggagga aaccagtccc aaggtccccc gcctcatccg
2401 ggaaagccag aaggaccacc cccacaagga ggaaaccagt cccaaggtcc cccacctcgt
2461 ccgggaaagc cagaaggacc acccccacaa ggaggaaacc agtcccaagg tcccccacct
2521 cgtccgggaa agccagaagg accaccccca caaggaggaa accagtccca aggtccccca
2581 cctcgtccgg gaaagccaga aggaccaccc ccacaaggag gaaaccagtc ccaaggtccc
2641 ccacctcgtc caggaaagcc agaaggatca ccttcacaag gaggcaacaa acctcgaggt
2701 cccccacctc atccaggaaa gccacaagga ccacccccac aagaaggcaa caaacctcaa
2761 cgtccccctc ctccaagaag gccacaagga ccacccccac caggaggcaa tccccagcag
2821 cctctgccac ctcccgctgg aaagccccag ggaccacctc cacctcctca agggggcaga
2881 ccacacagac ctccccaggg acagcctccc cagtaatcaa ggttcaatga caggtatgat
2941 tccagtttat tcttcaccaa gtgctctaca gtgttacagt tctccaactt tattgtgcca
3001 atgaatcaac taaaaaccca ttgacattgt attgtcctag aacccatttc taaagatttg
3061 tattcagata ctctggaata gggtaagaag accctgtatt tctaacaaac tctttaagga
3121 actctgatgt tgagaaacaa cataccatac aatctgtctt aaattgtgtt ggcaatgagg
3181 aagtagtacc atgtccattc ttggtgctct gctttcggtc cacaaactca gagatattgc
3241 atttaaattt ttcacctgag cactgtttgc tcattcctgc ctcacgccag cctctcgagt
3301 ccagtattcc tgccaaatgg tccctgatct ttcagcagct aaatggtgtc tcatttttta
3361 catacttagt tttcagtaag tacatgatta agctaacaaa agatatctaa tggaatggaa
3421 aaatatgaag ttaattttaa aggcgtagct catcctactc accttccttc cttcaaaaag
3481 ctaccactgt tgactttatg ggatcttctc tttgaaatat ttatgtgtgc atagacatac
3541 agcattcttt taccctacca ctaataccat aacttatatg caggtatata tggtagtcat
3601 ttaaaaatac acttcttgaa aatttccaca tcagtttatg aagctaaata catctcttca
3661 gtggttttct gtttgctttt acaattttat gctactccat tgtgtggctg caccatgatt
3721 tctttaatca atccctgtca ctggatactg agggtggttt catcttatca ctattataaa
3781 ataggttctg attatcatat gtgtaaatat atccctgaac aaattcaaca gcaatgagtc
3841 ataacaacct aaggatgatc ttttctcttc atcttctcag caacaatttg gagcacattg
3901 tgtgcaaggg catcaaaaga gtgaacacag aaaaaatcag gaaagaatca caggaggttg
3961 aagggattgg ggagagagga tgggatctca tgtactctac tgcagtaaca ccagtgagga
4021 attcgacatt tcctgccatg tcaagtctgc tctatgaaat tccttgttct gtttgtttca
4081 ggaagtgaac aagaagatga cagtgattca aatgattcaa atgccatgac attggaagaa
4141 ggtggtcata gctctacctt taatatacca ataaaacaaa cagcttacaa tttctgattg
4201 tggtgtctct ttctcagtgt ttgtgaatgt ggagtgtgag gaccaagaac acattataag
4261 aacatctagg accccttctc tttgatgctt ccagggagat tccctcctct ttaatcctaa
4321 tttagccagc tgccatgaaa aatattttac tgtttatctc cttccctgac ttctattttt
4381 ttctttttct gaaatggagt cttgctctat cacctaggtt ggagtgcagt ggcataatct
4441 tggctcacta caacctgcat ctcctggatt caagctattc tcctacctca cccttcacag
4501 tagctgggat tacagg
//