GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMREL4 558 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA for prepro-relaxin H1
ACCESSION X00949
KEYWORDS hormone; relaxin; signal peptide.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS Hudson,P., Haley,J., John,M., Cronk,M., Crawford,R.,
Haralambidis,J., Tregear,G.W., Shine,J. and Niall,H.
TITLE Structure of a genomic clone encoding biologically active human
relaxin
JOURNAL Nature 301, 628-631 (1983)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 558)
AUTHORS Hudson,P., John,M., Crawford,R., Haralambidis,J., Scanlon,D.,
Gorman,J., Tregear,G.W., Shine,J. and Niall,H.
TITLE Relasin gene expression in human ovaries and the predicted
structure of a human preprorelaxin by analysis of cDNA clones
JOURNAL EMBO J. 3, 2333-2339 (1984)
STANDARD full automatic
COMMENT SWISS-PROT; P04808; REL1$HUMAN.
Data kindly reviewed (15-MAY-1985) by R. Crawford
From EMBL entry HSREL4; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 1..555
/note="prepro-relaxin H1"
/codon_start=1
CDS 1..75
/note="signal peptide"
/codon_start=1
CDS 76..171
/note="B-chain"
/codon_start=76
CDS 172..483
/note="C-peptide"
/codon_start=172
CDS 484..555
/note="A-chain"
/codon_start=484
BASE COUNT 170 a 125 c 117 g 146 t
ORIGIN
1 atgcctcgcc tgttcttgtt ccacctgcta gaattctgtt tactactgaa ccaattttcc
61 agagcagtcg cggccaaatg gaaggacgat gttattaaat tatgcggccg cgaattagtt
121 cgcgcgcaga ttgccatttg cggcatgagc acctggagca aaaggtctct gagccaggaa
181 gatgctcctc agacacctag accagtggca gaaattgtac catccttcat caacaaagat
241 acagaaacta taattatcat gttggaattc attgctaatt tgccaccgga gctgaaggca
301 gccctatctg agaggcaacc atcattacca gagctacagc agtatgtacc tgcattaaag
361 gattccaatc ttagctttga agaatttaag aaacttattc gcaataggca aagtgaagcc
421 gcagacagca atccttcaga attaaaatac ttaggcttgg atactcattc tcaaaaaaag
481 agacgaccct acgtggcact gtttgagaaa tgttgcctaa ttggttgtac caaaaggtct
541 cttgctaaat attgctga
//