GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMSBA1 1048 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA for SB classII histocompatibility antigen alpha-chain
ACCESSION X00457
KEYWORDS antigen; membrane protein; signal peptide.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1048)
AUTHORS Auffray,C., Lillie,J.W., Arnot,D., Grossberger,D., Kappes,D. and
Strominger,J.L.
TITLE Isotypic and allotypic variation of human class II
histocompatibility antigen alpha-chain genes
JOURNAL Nature 308, 327-333 (1984)
STANDARD full automatic
COMMENT SWISS-PROT; P01905; HA2P$HUMAN.
From EMBL entry HSSBA1; dated 06-JUL-1989.
FEATURES Location/Qualifiers
CDS 1..13
/note="signal peptide fragment"
/codon_start=1
CDS 14..265
/note="alpha 1"
/codon_start=14
CDS 266..547
/note="alpha 2"
/codon_start=266
CDS 548..586
/note="(CP) connecting peptide"
/codon_start=548
CDS 587..655
/note="(TM) transmembrane region"
/codon_start=587
CDS 656..700
/note="(CY) cytoplasmatic region"
/codon_start=656
polyA_site 1048..1048
/note="polyadenylation site"
BASE COUNT 255 a 285 c 248 g 260 t
ORIGIN
1 aggagctggg gccatcaagg cggaccatgt gtcaacttat gccgcgtttg tacagacgca
61 tagaccaaca ggggagttta tgtttgaatt tgatgaagat gagatgttct atgtggatct
121 ggacaagaag gagaccgtct ggcatctgga ggagtttggc caagcctttt cctttgaggc
181 tcagggcggg ctggctaaca ttgctatatt gaacaacaac ttgaatacct tgatccagcg
241 ttccaaccac actcaggcca ccaacgatcc ccctgaggtg accgtgtttc ccaaggagcc
301 tgtggagctg ggccagccca acaccctcat ctgccacatt gacaagttct tcccaccagt
361 gctcaacgtc acgtggctgt gcaacgggga gctggtcact gagggtgtcg ctgagagcct
421 cttcctgccc agaacagatt acagcttcca caagttccat tacctgacct ttgtgccctc
481 agcagaggac ttctatgact gcagggtgga gcactggggc ttggaccagc cgctcctcaa
541 gcactgggag gcccaagagc caatccagat gcctgagaca acggagactg tgctctgtgc
601 cctgggcctg gtgctgggcc tagtcggctt catcgtgggc accgtcctca tcataaagtc
661 tctgcgttct ggccatgacc cccgggccca ggggaccctg tgaaatactg taaaggtgac
721 aaaatatctg aacagaagag gacttaggag agatctgaac tccagctgcc ctacaaactc
781 catctcagct tttcttctca cttcatgtga aaactactcc agtggctgac tgaattgctg
841 acccttcaag ctctgtcctt atccattacc tcaaagcagt cattccttag taaagtttcc
901 aacaaataga aattaatgac actttggtag cactaatatg gagattatcc tttcattgag
961 ccttttatcc tctgttctcc tttgaagagc ccctcactgt caccttcccg agaataccct
1021 aagaccaata aatacttcag tatttcag
//