GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMMBPX45 556 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human MBP gene for myelin basic protein, exons 4 and 5
ACCESSION X17288
KEYWORDS myelin; myelin basic protein; structural protein.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 556)
AUTHORS Hofmann,K.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 1 to 556)
AUTHORS Streicher,R. and Stoffel,W.
TITLE The Organization of the Human Myelin Basic Protein Gene -
Comparison with the Mouse Gene
JOURNAL Biol. Chem. Hoppe-Seyler 370, 503-510 (1989)
STANDARD full automatic
COMMENT *source: library=pcos2 EMBL, Charon 4A; clone=MBPNterm, MBPCterm;
**map: chromosome=18; See X17286, X17287, X17290, X17288, X17369
and X17289, respectively for myelin basic protein gene exons 1-7.
Data kindly reviewed (20-JUN-1990) by Hofmann K.
From EMBL entry HSMBPX45; dated 06-JUL-1990.
FEATURES Location/Qualifiers
precursor_RNA <1..>556
/note="primary transcript"
intron <1..24
/note="intron III"
mRNA 25..60
/note="exon 4"
CDS 25..60
/note="myelin basic protein (AA 121-132)"
/codon_start=25
intron 61..406
/note="intron IV"
mRNA 407..439
/note="exon 5"
CDS 407..439
/note="myelin basic protein (AA 133-143)"
/codon_start=407
intron 440..>556
/note="intron V"
BASE COUNT 103 a 178 c 122 g 153 t
ORIGIN
1 gccagggttc tctgtgcctt tcaggtgacg cctcgcacac cacccccgtc gcagggaaag
61 gtaagacctt ggaatgtttt gattgatcat cacttttctg atagaccttc tctaaaatcc
121 cataatgtac caaagagaga gttaggctcc gagctaccag aatccatccc aaaacgtgtt
181 gccaggcagc tcccaagtag aacaggtcgg agatccatgc acccctcctg tccctcccgc
241 acctgcacag ccgctgtggc cctagctgcg gcccccctcg gagctccggg tggaacctgt
301 ttttaccacc tcagctccac tgtgctttga ctgtgtttcc tgttgattga aaggactttc
361 ccttcactga ccaccatgtc attatttctc tgtcttcctc atgcagggga gaggactgtc
421 cctgagcaga tttagctggg taggtgacga acgcacttcc atcggcttcc tcttccgtcc
481 cagtcctcac agccccgcaa cttttgtgtt ctgctctgtt tcggttgctt cctggcctcc
541 ttttctctcc tctcga
//