[bionet.molbio.genbank.updates] Human gene for tyrosine aminotransferase

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT1       792 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 1.
ACCESSION   X52508
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 792)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1 + cDNA
            made by RT-PCR. **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT1;  dated 19-JUL-1990.
FEATURES             Location/Qualifiers
     promoter        623..631
                     /note="pot. CAAT box"
     promoter        669..675
                     /note="pot. TATA box"
     mRNA            701..784
                     /note="exon 1"
     intron          785..>792
                     /note="intron I"
BASE COUNT      234 a    139 c    198 g    221 t
ORIGIN
        1 taaaactgca caggtttcag ctgccttgga caccctgtgc ttttcagcta tttgttgaat
       61 ggaacttaag tgcccaattt gttctgattg gagcaaaact ttgtggactg acaaggatgg
      121 gcgtccaaga tgtaggaagt taaaaaaaaa atgttgccaa acaaggtgta gagcacgatc
      181 ctatctgtgt tttgaaatct atgaaattat gtatctatgc acctatatgt aatgtatcta
      241 tctctgaatg gagggaaaga gcctgaccat taccaccctc tacccctggg agtgagaatg
      301 aagtgtacag ggagcaggtg caaggaagaa tgctcacttc ttactttata tatttctgta
      361 ctgttaaaat tttaactggc tgttttgtaa aaaaaattta ataaaagcta tcaactgtaa
      421 ccagaagtac tttctgacag tagatgttct caaaccatct caccaagtgc ccagaaagag
      481 ttaacacagg agaattccag atgtttgaag tgagaacaaa ttcctgcttt gagggtggga
      541 ggtgggctta gggatgagag gcaatgacgg gggagaggag gaaagaagct gaggggagag
      601 ctggctgctg agttgtcatt ccaaccaatg gcatgaaagt ttcaagccca acgcccattt
      661 gtggagacta tttcaggagt taggatttgc atctgagttc attgcccctg taacctgtca
      721 aagaagagct aagggagctt tcggggttgg cttcttggag gctgctttct cctttacttg
      781 gaaggtaaaa at
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT10      106 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon
            10.
ACCESSION   X52517
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 106)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 106)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT10;  dated 19-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..15
                     /note="intron IX"
     mRNA            16..99
                     /note="exon 10"
     CDS             16..99
                     /note="tyrosine aminotransferase (AA 348-375)"
                     /codon_start=16
     intron          100..>106
                     /note="intron X"
BASE COUNT       13 a     31 c     29 g     33 t
ORIGIN
        1 tgcctcttct tgtagtccaa tgctgatctc tgttatgggg cgttggctgc catccctgga
       61 ctccggccag tccgcccttc tggggctatg tacctcatgg tgagta
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT11      122 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon
            11.
ACCESSION   X52518
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 122)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 122)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT11;  dated 18-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..15
                     /note="intron X"
     mRNA            16..114
                     /note="exon 11"
     CDS             16..114
                     /note="tyrosine aminotransferase (AA 376-408)"
                     /codon_start=16
     intron          115..>122
                     /note="intron XI"
BASE COUNT       26 a     25 c     38 g     33 t
ORIGIN
        1 ctcctgttgg tataggttgg aattgagatg gaacatttcc cagaatttga gaacgatgtg
       61 gagttcacgg agcggttagt tgctgagcag tctgtccact gcctcccagc aacggtgggt
      121 gc
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT12     1483 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon
            12.
ACCESSION   X52519
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1483)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT3a-6; **map: chromosome=16q22.1; See <X52507>-<X52520>. Data
            kindly reviewed (26-JUL-1990) by Scherer G.
            
            From EMBL    entry HSTAT12;  dated 07-AUG-1990.
FEATURES             Location/Qualifiers
     intron          <1..20
                     /note="intron XI"
     mRNA            21..1454
                     /note="exon 12"
     CDS             21..158
                     /note="tyrosine aminotransferase (AA 409-454)"
                     /codon_start=21
     misc_feature    770..775
                     /note="minor mRNA polyadenylation signal"
     polyA_site      790..790
                     /note="minor mRNA polyadenylation site"
     repeat_region   816..830
                     /note="direct repeat flanking Alu element"
     misc_feature    complement(831..1179)
                     /note="Alu element"
     repeat_region   1180..1194
                     /note="direct repeat flanking Alu element"
     misc_feature    1438..1443
                     /note="major mRNA polyadenylation signal"
     polyA_site      1454..1454
                     /note="major mRNA polyadenylation site"
BASE COUNT      375 a    325 c    305 g    478 t
ORIGIN
        1 acagactctt ctttttgcag tgctttgagt acccgaattt catccgagtg gtcatcacag
       61 tccccgaggt gatgatgctg gaggcgtgca gccggatcca ggagttctgt gagcagcact
      121 accattgtgc tgaaggcagc caggaggagt gtgataaata ggcctgcatc cattctcctg
      181 aggatgtgtc ccatctaggg aaggctggac taggccttgc ggctcctcag ggactcaggt
      241 ggccctactg ggagaggggc ctcaaatgca ccatgtcaag ggttcaagat tgttcctgct
      301 tttccccaag tacaaccaca cccacactca gatcctcctc attcacatcg cagattactc
      361 ccttgctctg cgctgctaga gtgactcact aattcattaa tctgcctccc tctcgtaaga
      421 tttccttctt ttttttcttg aaagtaccag gtgaacaaag tttaccagaa agcagttgag
      481 acaagaaaat aagagctcag gatgagggaa aagaaaaaga ttgagagaat ttgtgccccc
      541 aaccatttcc tcagactcta agaaagaaca cgctctctcc aggcaggtct gaagctcaac
      601 tctcttattg cctcacttca ggtatacctc actttacaca atagaattat aactggaaag
      661 aagttgggga cacatgtatt tggtgattac attttaaaca cattaggaaa agttgctatt
      721 tgaacttttt attgattttt ggggggagta aagaattatt ttggatgcaa ataaatatcc
      781 tttaattgat cgacttgcca aatttagatt tgtgtgcatc aggctttctt ttttttcttt
      841 ttttagagaa gttcaatata agcttttctt ttctttgttt ctttctttct ttattttgag
      901 atggagtctt gctctgtcgc ccatgctgga gtgcagtggc gcgatctcgg ctcactgcaa
      961 cctccacctc ctgggttcaa gcgattctct tgcctcaacc tcccaagcag ttgggactac
     1021 aggcgtgagc caccatgccc ggctaatttt tgtattttta gtagagacag ggtttcacca
     1081 tgttagccag gctggtctca aactcctgac ctcaggcaat ctgcccgcct gggtctccta
     1141 aagtactggg attacaggcg tgagccacct cgcccagcgg catcaggctt tcttaaagtg
     1201 agagcacgcc tgtactagag caagcaggaa tcagagacct tccagaaata ctactgtgta
     1261 agggccagaa atatcttcac ttgtcattgt tatataatca ttattacttt tgctgtaatg
     1321 ttaatattga tttattaata tatattatct tttcatacat tttctaagaa acatttatat
     1381 tgataagatc ttttattttg caagggcata aattattgtt tttctttttt tttttttaat
     1441 aaatttcacc aagtatggct cttctgtgat gtgttttttt ctc
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT2       286 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 2.
ACCESSION   X52509
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 + cDNA made by RT-PCR. **map: chromosome=16q22.1; See
            <X52507>-<X52520>.
            
            From EMBL    entry HSTAT2;  dated 19-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..31
                     /note="intron I"
     mRNA            32..278
                     /note="exon 2"
     CDS             44..278
                     /note="tyrosine aminotransferase (AA 1-78) (278 is 1st
                     base in codon)"
                     /codon_start=44
     intron          279..>286
                     /note="intron II"
BASE COUNT       84 a     73 c     70 g     59 t
ORIGIN
        1 aacatcacag ggaacttctt tcccctcgca ggcttcgcta gtgatggacc catacatgat
       61 tcagatgagc agcaaaggca acctcccctc aattctggac gtgcatgtca acgttggtgg
      121 gagaagctct gtgccgggaa aaatgaaagg cagaaaggcc aggtggtctg tgaggccctc
      181 agacatggcc aagaaaactt tcaaccccat ccgagccatt gtggacaaca tgaaggtgaa
      241 accaaatcca aacaaaacca tgatttccct gtccattggt gagttg
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT3       127 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 3.
ACCESSION   X52510
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 127)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 127)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16. Data kindly reviewed (26-JUL-1990) by Scherer G. **map:
            chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT3;  dated 07-AUG-1990.
FEATURES             Location/Qualifiers
     intron          <1..14
                     /note="intron II"
     mRNA            15..119
                     /note="exon 3"
     CDS             15..119
                     /note="tyrosine aminotransferase (AA 79-113) (15 is 2nd
                     base in codon) (119 is 1st base in codon)"
                     /codon_start=15
     intron          120..>127
                     /note="intron III"
BASE COUNT       36 a     37 c     28 g     26 t
ORIGIN
        1 cctcccataa aaaggggacc ctactgtgtt tggaaacctg cctacagacc ctgaagttac
       61 ccaggcaatg aaagatgccc tggactcggg caaatataat ggctatgccc catccatcgg
      121 taagctc
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT4        92 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 4.
ACCESSION   X52511
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 92)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 92)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16. **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT4;  dated 19-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..16
                     /note="intron III"
     mRNA            17..84
                     /note="exon 4"
     CDS             17..84
                     /note="tyrosine aminotransferase (AA 114-136) (17 is 2nd
                     base in codon)"
                     /codon_start=17
     intron          85..>92
                     /note="intron IV"
BASE COUNT       18 a     26 c     20 g     28 t
ORIGIN
        1 cactcttttc tttcaggctt cctatccagt cgggaggaga ttgcttctta ttaccactgt
       61 cctgaggcac ccctagaagc taaggtgagc ct
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT5       184 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 5.
ACCESSION   X52512
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 184)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 184)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16. **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT5;  dated 19-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..17
                     /note="intron IV"
     mRNA            18..176
                     /note="exon 5"
     CDS             18..176
                     /note="tyrosine aminotransferase (AA 137-189)"
                     /codon_start=18
     intron          177..>184
                     /note="intron V"
BASE COUNT       43 a     42 c     41 g     58 t
ORIGIN
        1 ttttatttcc ttcacaggac gtcattctga caagtggctg cagccaagct attgaccttt
       61 gtttagctgt gttggccaac ccagggcaga acatcctggt tccaagacct ggtttctctc
      121 tctacaagac tctggctgag tctatgggaa ttgaggtcaa actctacaat ttgttggtaa
      181 atga
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT6       163 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 6.
ACCESSION   X52513
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 163)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 163)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 **map: chromosome=16q22.1; See <X52507>-<X52520>. Data
            kindly reviewed (26-JUL-1990) by G. Scherer
            
            From EMBL    entry HSTAT6;  dated 07-AUG-1990.
FEATURES             Location/Qualifiers
     intron          <1..16
                     /note="intron V"
     mRNA            17..155
                     /note="exon 6"
     CDS             17..155
                     /note="tyrosine aminotransferase (AA 190-236) (155 is 1st
                     base in codon)"
                     /codon_start=17
     intron          156..>163
                     /note="intron VI"
BASE COUNT       49 a     39 c     31 g     44 t
ORIGIN
        1 catcctttct ctccagccag agaaatcttg ggaaattgac ctgaaacaac tggaatatct
       61 aattgatgaa aagacagctt gtctcattgt caataatcca tcaaacccct gtgggtcagt
      121 gttcagcaaa cgtcatcttc agaagattct ggcaggtacg tcc
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT7        76 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 7.
ACCESSION   X52514
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 76)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full staff_review
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT7;  dated 18-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..16
                     /note="intron VI"
     mRNA            17..69
                     /note="exon 7"
     CDS             17..69
                     /note="tyrosine aminotransferase (AA 236-253) (17 is
                     second base in codon)"
                     /codon_start=17
     intron          70..>76
                     /note="intron VII"
BASE COUNT       15 a     15 c     21 g     25 t
ORIGIN
        1 catgttttat tttcagtggc tgcacggcag tgtgtcccca tcttagctga tgagatctat
       61 ggagacatgg tgagtc
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT8       175 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 8.
ACCESSION   X52515
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 175)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 175)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT8;  dated 18-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..15
                     /note="intron VII"
     mRNA            16..168
                     /note="exon 8"
     CDS             16..168
                     /note="tyrosine aminotransferase (AA 254-304)"
                     /codon_start=16
     intron          169..>175
                     /note="intron VIII"
BASE COUNT       34 a     46 c     49 g     46 t
ORIGIN
        1 agtccctctt ctcaggtgtt ttcggattgc aaatatgaac cactggccac cctcagcacc
       61 gatgtcccca tcctgtcctg tggagggctg gccaagcgct ggctggttcc tggctggagg
      121 ttgggctgga tcctcattca tgaccgaaga gacatttttg gcaatgaggt gataa
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTAT9       151 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon 9.
ACCESSION   X52516
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 151)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 151)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT2-16 **map: chromosome=16q22.1; See <X52507>-<X52520>.
            
            From EMBL    entry HSTAT9;  dated 18-JUL-1990.
FEATURES             Location/Qualifiers
     intron          <1..15
                     /note="intron VIII"
     mRNA            16..144
                     /note="exon 9"
     CDS             16..144
                     /note="tyrosine aminotransferase (AA 305-347)"
                     /codon_start=16
     intron          145..>151
                     /note="intron IX"
BASE COUNT       32 a     38 c     43 g     38 t
ORIGIN
        1 ctgtggtgtc tttagatccg agatgggctg gtgaagctga gtcagcgcat tttgggaccc
       61 tgtaccattg tccagggagc tctgaaaagc atcctatgtc gcaccccggg agagttttac
      121 cacaacactc tgagcttcct caaggtaggg c
//

GenBank-Updates@genbank.bio.net (05/30/91)

LOCUS       HUMTATG5     1600 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5)
            5'-flanking region
ACCESSION   X52507
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1600)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1600)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     *source: tissue=placenta; *source: library=genomic (phage); clone=
            lambda-hTAT1; **map: chromosome=16q22.1; See <X52507>-<X52520>.
            This sequence corresponds to positions -3520 to -1921 (approximate
            positions) relative to the transcription start site. Data kindly
            reviewed (26-JUL-1990) by G. Scherer.
            
            From EMBL    entry HSTATG5;  dated 07-AUG-1990.
FEATURES             Location/Qualifiers
     misc_feature    complement(628..936)
                     /note="Alu element"
     misc_feature    complement(937..1242)
                     /note="Alu element"
BASE COUNT      409 a    371 c    296 g    524 t
ORIGIN
        1 gacctgcagg tcaacggatc cagttttagc aaagaaccct gagtcatttt ggcaagattt
       61 cccaccctgc atatctgacc aggttcctca ttctttgccg tcccccaggg aatgtttggt
      121 caccatggcc tgtcttcaag caggatgaca ctgacactgg ccttctagtt cagtttagca
      181 gaatcccctt actcctgatg attcctctta ctttttccat ccttggctat aaatccacac
      241 ttgccatcac catatttgga gttgaatcca atttctcttc cccactggaa aatccattgc
      301 agtgggccgt ctagctattg gaatggtcct gaataaagtc tgccttacca tgctttaaca
      361 agtgttattg aataattttt tttaacacct ctgagtctct gtccacctga gaaccactac
      421 agtaacactc agtgaggtac ctgtgtcatc tctcaagcac agtatattgt catgacaggt
      481 agtctgaact ccaagaggtt gttcaaatta aacatatttg cattgctttc gtctttgtat
      541 agtccgtaat tgaaactatc cctcaaataa caggatatgc ataaaagttc tctatcaatc
      601 atgaatgtac aaggagattc gatatgcttt attttttatt ttatttattt atttattgag
      661 acagagtctg gctctgtcgc ccaggctgga gtgcagtggc gcgacctcag ttcactgcaa
      721 gctccgcctc ccggattcat gccattctcc tccctcagcc tcccgagtag ctgggactac
      781 aggcacccgc caccaggctg ggctaacttt tgtattttta gcggagatgg ggtttcacgg
      841 tgttagccag gatggtctcc atctcctgac ctcgtgatcc gcctgcctca gcaccccaaa
      901 gtgctgggat tataggcgtg agccaccaca ccaggctatt tatttttatt ttttattttt
      961 tgagacggag tctcactctg tcgcccagac tggagtgcag tggcacgatc tcggctcacc
     1021 acaacctcca cctcctgggt tcaagcgatt ctcctccctc agcctcctga gttgctggga
     1081 ttacaggtgt gcaccactgt gcctggctaa ttgttgtatt tttagtagag atggggtttt
     1141 gccatgttgg ccaggttggt cttgaactcc tgatctcaga tgatctgcct gccttggcct
     1201 ccaaagtgct ggggttacag gcatgagctg ccacgcccag cccacacatt attaagattt
     1261 taaaaaaagc aagctacaga acagccctgt ccaatagaca gaatgcaagc cacatagtga
     1321 cctcaaattt cctaatagaa atattttaag atataaaaac aaataggtga aattaattta
     1381 agaatgtatt ttattttact cagcacacca tgtattttat tatcatatat tttattatat
     1441 atattttatt atatatatac cggtgtactg aggaaaatac atttttatat atatatacat
     1501 atatatatat atatatatat acatatatat atatatatat atatatatat tttttttttt
     1561 tttttttttt tttctgaggc aaggtctcat tctgtcaccc
//